@article{jeong_premanandan_her_2024, title={A Retrospective Review of Morbidity and Mortality in ‘Good Samaritan’ Animals Admitted to a Tertiary Referral Veterinary Health Center From 2014 to 2022: Postmortem Examination}, url={https://doi.org/10.56771/jsmcah.v3.83}, DOI={10.56771/jsmcah.v3.83}, abstractNote={Introduction: Good Samaritan animals are frequently encountered at veterinary teaching hospitals and provide a useful indirect surveillance tool for monitoring major morbidity and mortality in unattended animals. Methods: Retrospective study. Good Samaritan animals’ medical and postmortem examination records were searched from the OSU VMC medical record database and the OSU CVM Anatomic pathology database and identified 100 cases from 2014 to 2022. Results: One hundred Good Samaritan animals that underwent postmortem examination were identified. These included 59 cats, 36 dogs, 2 raccoons, 1 squirrel, 1 bat, and 1 opossum with mean and median ages of 2.61 years and 1 year, respectively. The most predominant cause of death or major morbidity requiring euthanasia was euthanasia for rabies test (n = 19) in cats and vehicular trauma (n = 16) in dogs. Other mortality and significant morbidities include trauma (n = 15) followed by infectious disease (n = 5) in cats and infectious disease (n = 12) and neoplasia (n = 2) in dogs. Brain tissue from 51 animals was submitted to the Ohio Department of Health for rabies tests, and all had negative results. In 17 canines and felines with infectious diseases, dogs had viral (n = 6), parasitic (n = 5), and bacterial (n = 1) etiologies, while cats had bacterial (n = 2) and viral (n = 1), fungal (n = 1), and mixed (n = 1) etiologies. Conclusion: Epidemiological review of morbidity and mortality in Good Samaritan animals submitted for postmortem examination helps to characterize the types and severity of vehicular trauma and infectious diseases in stray animals. Young and intact animals were important demographic factors in Good Samaritan dogs and cats. The rabies test results tightly correlate with a trend of rabies test results in dogs and cats in Franklin County.}, journal={Journal of Shelter Medicine and Community Animal Health}, author={Jeong, Yea Ji and Premanandan, Christopher and Her, Jiwoong}, year={2024}, month={Sep} } @article{merbl_her_grandprey_bini_strahl-heldreth_hofmeister_2024, title={A retrospective case-control study evaluating systemic blood pressure and heart rate in dogs with brain herniation under general anesthesia}, url={https://doi.org/10.1016/j.vaa.2024.05.003}, DOI={10.1016/j.vaa.2024.05.003}, journal={Veterinary Anaesthesia and Analgesia}, author={Merbl, Yael and Her, Jiwoong and Grandprey, Brianna and Bini, Gianluca and Strahl-Heldreth, Danielle and Hofmeister, Erik}, year={2024}, month={Sep} } @article{seo_lim_namgoong_uhm_hong_lee_kim_heo_kang_kim_et al._2024, title={Assessment of changes in intra-abdominal pressure and cardiac output induced by liver compression in healthy anesthetized spontaneously breathing dogs}, url={http://dx.doi.org/10.1371/journal.pone.0315491}, DOI={10.1371/journal.pone.0315491}, abstractNote={Objective Liver compression (LC) has been proposed to predict fluid responsiveness in human pediatric patients. Because the evaluation of fluid responsiveness through LC depends on the mechanism of increased intra-abdominal pressure (IAP), understanding the impact of LC on IAP, cardiac output (CO), and respiratory parameters is essential. Thus, this study aimed to investigate the effects of LC on these parameters. Methods The present study used six healthy beagles. All dogs were anesthetized with isoflurane and allowed to breathe spontaneously in dorsal recumbency. After instrumentation, LC was performed at four different pressures in a sequential, non-randomized manner: (1) 10 mmHg, approximately half of the minimum value within the range; (2) 22 mmHg, a commonly used pressure within the range; (3) 44 mmHg, twice the pressure of the minimum value within the range; and (4) 60 mmHg, twice the pressure of the maximum value within the range. At each pressure, CO via transthoracic echocardiography, IAP, and cardiorespiratory parameters were measured before, during, and after LC. Results Overall, our results showed that the IAP was significantly increased at all pressures during LC (P < 0.001), yielding a linear correlation between LC pressure and IAP (P < 0.001; r² = 0.89). The maximum IAP during LC was 7 mmHg, and intra-abdominal hypertension was not induced. LC at 22 mmHg significantly increased the IAP by 1.7 mmHg, but did not significantly alter the CO or respiratory parameters. Conclusions This is the first study to evaluate the effects of LC on IAP, CO, and respiratory parameters in healthy, anesthetized, and spontaneously breathing dogs. Our findings indicate that applying LC with a commonly used pressure may have a low risk of inducing intra-abdominal hypertension and related complications. Further studies are required to explore the use of LC in various clinical settings.}, journal={PLOS ONE}, author={Seo, Daeyun and Lim, Seongsoo and Namgoong, Beomkwan and Uhm, Heesung and Hong, Hyeajeong and Lee, Nanju and Kim, Isong and Heo, Seunghun and Kang, Ji Hwan and Kim, Cheyoun and et al.}, year={2024}, month={Dec} } @article{seo_lim_namgoong_choe_uhm_hong_lee_kim_heo_her_et al._2024, title={Evaluation of fluid responsiveness using liver compression in dogs with experimentally induced hypovolemia}, url={https://doi.org/10.2460/ajvr.24.03.0083}, DOI={10.2460/ajvr.24.03.0083}, abstractNote={To investigate whether liver compression (LC) could increase stroke volume (SV) by more than 15% in healthy, anesthetized dogs with hypovolemia and suggest LC as a novel method to evaluate fluid responsiveness.}, journal={American Journal of Veterinary Research}, author={Seo, Daeyun and Lim, Seongsoo and Namgoong, Beomkwan and Choe, Ahreum and Uhm, Heesung and Hong, Hyeajeong and Lee, Nanju and Kim, Isong and Heo, Seunghun and Her, Jiwoong and et al.}, year={2024}, month={Oct} } @article{randolph_her_mcaloney_wellman_2024, title={Gastrointestinal colonization by Diutina (Candida) rugosa in a 6‐year‐old Siberian Husky}, url={https://doi.org/10.1111/vcp.13335}, DOI={10.1111/vcp.13335}, abstractNote={Abstract A 6‐year‐old 21.5 kg castrated male Siberian Husky was presented for acute onset of lethargy, vomiting, hemorrhagic diarrhea, and inappetence. Physical examination revealed marked discomfort upon abdominal palpation and 5%–7% dehydration. The CBC and biochemical profile revealed changes consistent with mild to moderate inflammation, dehydration, and gastrointestinal (GI) disease. Despite aggressive gastrointestinal support, anorexia persisted, and an upper GI endoscopy was performed in conjunction with esophagostomy tube placement. Endoscopy revealed abnormal gastric mucosa characterized by moderately well‐demarcated areas of blue‐black discoloration. Impression smears of a gastric biopsy revealed abundant extracellular yeasts with morphology most consistent with Candida spp. and frequent extracellular cocci. Similar yeast and bacteria, in lower numbers, were observed on cytologic analysis of a direct smear of the rectal mucosa. A rectal swab submitted for fungal culture yielded pure growth of fungal yeasts identified as Diutina (formerly Candida ) rugosa by matrix‐assisted laser desorption‐ionization time‐of‐flight mass spectrometry. The dog's clinical signs improved with fluconazole, and he was discharged. Follow‐up fungal culture of a rectal swab showed no growth of D. rugosa . To the authors' knowledge, this is the first case report that describes the clinical, hematologic, cytologic, and gross findings of enteric colonization by D. rugosa in a dog.}, journal={Veterinary Clinical Pathology}, author={Randolph, Nina K. and Her, Jiwoong and McAloney, Camille A. and Wellman, Maxey}, year={2024}, month={Jun} } @article{her_verwaerde_baker_allaouchiche_pouzot-nevoret_2024, title={High-flow nasal cannula oxygen therapy in seven cats with respiratory failure}, url={https://doi.org/10.1177/1098612X241249837}, DOI={10.1177/1098612X241249837}, abstractNote={This case series describes seven cats that were treated with high-flow nasal cannula oxygen therapy (HFNOT). Seven cats were prospectively (n = 5) or retrospectively (n = 2) included from three veterinary university referral centers between March 2020 and September 2023. Data on signalment, medical history, clinical and diagnostic findings, treatment administered, response to HFNOT and outcomes were recorded. All cats included in this case series failed to respond to oxygen cage or flow-by oxygen therapy and were subsequently transitioned to HFNOT. After this transition, these cats demonstrated a marked improvement in respiratory parameters, including respiratory rate, effort and oxygen saturation measured by pulse oximetry, within 1 h of initiating HFNOT. All cats tolerated HFNOT well without any complications.}, journal={Journal of Feline Medicine and Surgery}, author={Her, Jiwoong and Verwaerde, Patrick and Baker, Chloe E and Allaouchiche, Bernard and Pouzot-Nevoret, Céline}, year={2024}, month={Jul} } @article{lee_lee_song_evans_her_2024, title={Preliminary evaluation of ionized magnesium levels in dogs on long-term esomeprazole administration}, volume={85}, ISSN={["1943-5681"]}, url={https://doi.org/10.2460/ajvr.24.05.0157}, DOI={10.2460/ajvr.24.05.0157}, abstractNote={Abstract OBJECTIVE To investigate the level of whole-blood ionized magnesium (iMg) in dogs with long-term use of proton pump inhibitors (PPIs). METHODS The study included 10 client-owned dogs with esomeprazole administration over 6 months and 62 healthy dogs to determine de novo reference interval (RI) of iMg. Dogs that received esomeprazole for 6 months or longer were retrospectively reviewed to determine the incidence of hypo- or hypermagnesemia based on the de novo RI. Additionally, the iMg levels from the study group were compared with those of 20 age-, sex-, and body weight–matched controls from the 62 dogs. RESULTS The median (range) duration of esomeprazole usage was 26 months (6 to 94). The de novo RI for iMg was determined as 0.73 (90% CI, 0.58 to 0.87) to 1.43 mg/dL (90% CI, 1.33 to 1.46). Based on the RI, none of the dogs with long-term esomeprazole developed hypo- or hypermagnesemia. The iMg from the matched control group was 1.17 mg/dL (90% CI, 0.83 to 1.46). The lowest iMg after 6 months of esomeprazole administration (90% CI, 0.96 mg/dL, 0.87 to 1.41) was significantly lower than the control group ( P = .031). The iMg measured at the end of long-term esomeprazole treatment was 1.03 mg/dL (90% CI, 0.87 to 1.41) and not significantly different from the control group ( P = .179). CONCLUSIONS Ionized hypomagnesemia was not observed after long-term use of esomeprazole in the small number of dogs included in this study. Robust RI needs to be determined in future studies to investigate the incidence of hypomagnesemia in dogs with long-term use of PPIs. CLINICAL RELEVANCE Future studies in a larger number of dogs are warranted to confirm the findings from the present study and to determine whether the long-term use of esomeprazole in dogs is at risk of developing ionized hypomagnesemia.}, number={12}, journal={AMERICAN JOURNAL OF VETERINARY RESEARCH}, author={Lee, Jeongmin and Lee, Seungkeun and Song, Kunho and Evans, Samantha and Her, Jiwoong}, year={2024}, month={Dec} } @article{eicher_young_hoover_kuo_her_2024, title={Retrospective evaluation of the respiratory rate–oxygenation index to predict the outcome of high‐flow nasal cannula oxygen therapy in dogs (2018–2021): 81 cases}, url={https://doi.org/10.1111/vec.13373}, DOI={10.1111/vec.13373}, abstractNote={Abstract Objective To evaluate the respiratory rate–oxygenation index (ROX), modified ROX index (ROX‐HR), and the ratio of pulse oximetry saturation (Sp o 2 ) to Fi o 2 (SF) to determine if these indices over time are predictive of outcome in dogs treated with high‐flow nasal cannula oxygen therapy (HFNC). Design Retrospective study. Setting Two university teaching hospitals. Animals Eighty‐one client‐owned dogs treated with HFNC for hypoxemic respiratory failure. Interventions None. Measurements and Main Results The ROX was defined as the SF divided by the respiratory rate (RR), and the ROX‐HR was defined as the ROX divided by the heart rate multiplied by 100. The overall success rate of HFNC was 44% ( n = 36/81). Dogs weaned from HFNC had a significantly higher ROX ( P < 0.0001) at 1–3, 5–10, 12, and 15 hours than dogs that failed HFNC. Both the ROX and SF showed excellent discriminatory power in predicting HFNC failure at 6 hours, with an area under receiver operating curve of 0.85 (95% confidence interval: 0.72–0.99; P < 0.002) and 0.86 (95% confidence interval: 0.73–0.99; P < 0.001), respectively. The optimal cutoff values for predicting HFNC failure at 6 hours were a ROX ≤3.68 (sensitivity 72%, specificity 92%) and an SF ≤143 (sensitivity 79%, specificity 93%). Conclusions These results suggest that similar to people, the ROX and SF are useful predictors of HFNC failure. These indices are easy to measure at the bedside and may have clinical use. Future prospective studies are warranted to confirm the findings and to optimize cutoff values in a larger population of dogs undergoing HFNC.}, journal={Journal of Veterinary Emergency and Critical Care}, author={Eicher, Logan and Young, Anda A. and Hoover, Leanna and Kuo, Kendon W. and Her, Jiwoong}, year={2024}, month={May} } @article{pinnell_her_gordon_kinsella_langston_toribio_2024, title={Successful hemodialysis treatment of a Quarter Horse mare with silver maple leaf toxicity and acute kidney injury}, url={https://doi.org/10.1111/jvim.17094}, DOI={10.1111/jvim.17094}, abstractNote={Abstract An adult American Quarter Horse mare presented for pigmenturia and lethargy of 12 hours' duration and was diagnosed with silver maple leaf toxicity. The mare had intravascular hemolysis and azotemia. The mare was treated with a transfusion of whole blood, fluids administered IV, antibiotics, oxygen insufflation, and supportive care. The azotemia persisted despite conventional medical management and hemodialysis was elected. After 2 intermittent hemodialysis treatments over 3 days, the azotemia almost resolved, clinical signs improved, and the mare was discharged. The blood urea nitrogen, creatinine, and electrolyte concentrations remained normal 6 months later after examination by the referring veterinarian. Hemodialysis treatment can be feasible in horses if equipment and expertise are available and should be considered as a treatment option if indicated.}, journal={Journal of Veterinary Internal Medicine}, author={Pinnell, Erin F. and Her, Jiwoong and Gordon, Daniel and Kinsella, Hannah M. and Langston, Catherine E. and Toribio, Ramiro E.}, year={2024}, month={Jul} } @article{thyen_riggs_her_yaxley_2024, title={Successful resolution of a continuous pneumothorax using canine xeno-blood patch pleurodesis in a cat}, url={https://doi.org/10.1177/20551169241265227}, DOI={10.1177/20551169241265227}, abstractNote={Case summary An 11-year-old male neutered cat was referred to The Ohio State University’s Veterinary Teaching Hospital after being diagnosed with pleural effusion by a referral veterinarian. After thoracocentesis, analysis of the effusion was consistent with chyle. Echocardiography, radiographs and bloodwork were used to diagnose hypertrophic cardiomyopathy phenotype and left-sided congestive heart failure, suspected to be secondary to uncontrolled hyperthyroidism. While initiating medical therapy, repeated thoracocenteses were required. A severe pneumothorax developed, necessitating placement of bilateral thoracostomy tubes. A thoracic CT scan did not reveal a cause for the pneumothorax; therefore, it was suspected to have occurred secondarily to an iatrogenic laceration of the parenchyma during thoracocentesis. An autologous blood patch pleurodesis was considered contraindicated so instead the cat was administered a blood patch using blood from a canine blood donor. The cat’s respiratory status remained stable without additional intervention. At 30 h after blood patch pleurodesis, the thoracostomy tubes were removed and thoracic radiographs revealed near resolution of the pleural effusion and pneumothorax. The cat remained subclinical and was discharged from the hospital 48 h after the blood patch pleurodesis. Upon follow-up at 4 and 8 weeks after discharge, the cat was alive and had no complications or adverse reactions from the blood patch pleurodesis. Relevance and novel information This case documents the first report of a xeno-blood patch pleurodesis performed in a cat using blood from a canine donor. The cat had a successful discharge from the hospital with no adverse reactions from the xeno-blood patch pleurodesis.}, journal={Journal of Feline Medicine and Surgery Open Reports}, author={Thyen, Anna K and Riggs, Alexandra H and Her, Jiwoong and Yaxley, Page E}, year={2024}, month={Jul} } @article{her_gordon_riggs_venner_cooper_langston_2024, title={Successful treatment of a severe 5‐hydroxytrytophan intoxication using carbon hemoperfusion, hemodiafiltration, and mechanical ventilation in a dog}, url={https://doi.org/10.1111/vec.13368}, DOI={10.1111/vec.13368}, abstractNote={Abstract Objective To describe the successful use of carbon hemoperfusion and hemodiafiltration in combination with mechanical ventilation (MV) to treat a severe intoxication of 5‐hydroxytryptophan (5‐HTP) in a dog. Case Summary A dog ingested a minimum of 550 mg/kg of extended‐release 5‐HTP, resulting in serotonin syndrome that progressed to a comatose state and severe hypoventilation requiring MV. Extracorporeal carbon hemoperfusion coupled with hemodiafiltration was performed to remove 5‐HTP from this patient. A carbon hemoperfusion cartridge was placed in series upstream in the extracorporeal circuit from the hemodialyzer. A total of 46.5 L of blood (4.89 L/kg) was processed during a 4.85‐hour treatment. Serial plasma samples were obtained at 0, 60, 90, and 150 minutes during the session and 14 hours after the session. These samples were later analyzed for 5‐HTP and serotonin concentrations. The extraction ratio of 5‐HTP was 93.6%–98.9% through the carbon filter. The dog was weaned from MV within 8 hours after extracorporeal therapy and, after a full recovery, was successfully discharged. New or Unique Information Provided Despite an extensive review of the available literature, this appears to be the first reported case of using a carbon hemoperfusion, hemodiafiltration, and MV to treat severe serotonin syndrome secondary to 5‐HTP intoxication in a dog. The combination of carbon hemoperfusion and hemodiafiltration can significantly reduce plasma 5‐HTP concentrations after acute intoxication and may serve to decrease morbidity and mortality in patients with severe intoxication.}, journal={Journal of Veterinary Emergency and Critical Care}, author={Her, Jiwoong and Gordon, Daniel and Riggs, Alexandra and Venner, Laura and Cooper, Edward and Langston, Catherine}, year={2024}, month={Mar} } @article{duble_her_preteseille_lee_allaouchiche_pouzot-nevoret_2024, title={The utility of the respiratory rate-oxygenation index as a predictor of treatment response in dogs receiving high-flow nasal cannula oxygen therapy}, url={http://dx.doi.org/10.3389/fvets.2024.1404195}, DOI={10.3389/fvets.2024.1404195}, abstractNote={Objective This study aims to evaluate the respiratory rate-oxygenation index (ROX) and the ratio of pulse oximetry saturation (SpO 2 ) to the fraction of inspired oxygen (FiO 2 ) (SpO 2 /FiO 2 , [SF]) to determine whether these indices are predictive of outcome in dogs receiving high-flow nasal cannula oxygen therapy (HFNOT). Design This is a prospective observational study. Setting This study was carried out at two university teaching hospitals. Animals In total, 88 dogs treated with HFNOT for hypoxemic respiratory failure due to various pulmonary diseases were selected. Measurements and main results The ROX index was defined as the SF divided by the respiratory rate (RR). ROX and SF were calculated at baseline and for each hour of HFNOT. The overall success rate of HFNOT was 38% ( N = 33/88). Variables predicting HFNOT success were determined using logistic regression, and the predictive power of each variable was assessed using the area under the receiver operating curve (AUC). ROX and SF were adequately predictive of HFNOT success when averaged over 0–16 h of treatment, with similar AUCs of 0.72 (95% confidence interval [CI] 0.60–0.83) and 0.77 (95% CI 0.66–0.87), respectively ( p < 0.05). SF showed acceptable discriminatory power in predicting HFNOT outcome at 7 h, with an AUC of 0.77 (95% CI 0.61–0.93, p = 0.013), and the optimal cutoff for predicting HFNC failure at 7 h was SF ≤ 191 (sensitivity 83% and specificity 76%). Conclusion These indices were easily obtained in dogs undergoing HFNOT. The results suggest that ROX and SF may have clinical utility in predicting the outcomes of dogs on HFNOT. Future studies are warranted to confirm these findings in a larger number of dogs in specific disease populations.}, journal={Frontiers in Veterinary Science}, author={Duble, Erin and Her, Jiwoong and Preteseille, Ingrid and Lee, Jeongmin and Allaouchiche, Bernard and Pouzot-Nevoret, Céline}, year={2024}, month={May} } @article{her_roh_keys_2024, title={Validation of Noninvasive Methemoglobin and Carboxyhemoglobin Measurements Using Pulse Co-Oximeter in Healthy Dogs}, volume={15}, ISSN={["2230-2034"]}, url={https://doi.org/10.2147/VMRR.S465945}, DOI={10.2147/VMRR.S465945}, abstractNote={To assess the agreement between pulse co-oximeter and blood co-oximeter in measuring methemoglobin (MetHb) and carboxyhemoglobin (COHb) in healthy, awake dogs.}, journal={VETERINARY MEDICINE-RESEARCH AND REPORTS}, author={Her, Jiwoong and Roh, Justin and Keys, Deborah A.}, year={2024}, pages={197–203} } @article{edmonds_her_langston_jennings_diaz_2024, title={Efficacy of therapeutic plasma exchange in a case of severe, generalised canine pemphigus foliaceus}, url={https://doi.org/10.1111/vde.13218}, DOI={10.1111/vde.13218}, abstractNote={Abstract Successful treatment of pemphigus foliaceus (PF) often requires a multimodal therapeutic approach. The dog described herein underwent four therapeutic plasma exchange treatments for severe, refractory PF, resulting in a 50% reduction of lesional body surface area. This treatment option should be considered for the management of canine PF.}, journal={Veterinary Dermatology}, author={Edmonds, Kaitlyn Bello and Her, Jiwoong and Langston, Catherine and Jennings, Ryan and Diaz, Sandra}, year={2024}, month={Apr} } @article{finstad_cooper_cate_yaxley_her_guillaumin_2023, title={Infrared thermography is a novel tool to assess small intestinal surface temperature in dogs undergoing laparotomy for foreign body obstruction}, url={http://dx.doi.org/10.2460/ajvr.23.04.0082}, DOI={10.2460/ajvr.23.04.0082}, abstractNote={To evaluate local temperature differences directly over and adjacent to small intestinal foreign body obstruction (FBO) using infrared thermography (IRT) in dogs.49 client-owned dogs were initially enrolled.In a prospective, clinical observational study, IRT was utilized to compare median small intestinal (SI) surface temperature differences at the site of FBO and segments oral and aboral before and after surgical resolution from April 24, 2019, to July 19, 2020. These differences were evaluated for correlation with canine acute patient physiologic and laboratory evaluation fast (APPLEfast) scoring, lactate, foreign body material (hard vs soft), and blood pressure.There was not a significant surface temperature difference between SI segments at the site of FBO, oral or aboral. After resolution of obstruction, there was a significant decrease in median temperature directly over the FBO (2.4 °C; IQR, -2.55 to 10.6 °C; P = .0043). A decrease in surface temperature of the oral SI segment was appreciated with FBO due to hard material (-1.7 °C; IQR, -5.2 to 3.4 °C), whereas soft material had an increase in SI surface temperature oral to the FBO (+1.1 °C; IQR, 0.3 to 3.2 °C). This difference did not achieve significance (P = .08; Z = 1.75). No correlation was found between APPLEfast, lactate, or blood pressure and SI segment temperatures.IRT may be useful diagnostic modality to identify changes in small intestinal surface temperature relating to FBO. Further evaluation is warranted to determine if IRT may be a clinically useful to evaluate intestinal perfusion.}, journal={American Journal of Veterinary Research}, author={Finstad, Joanna B. and Cooper, Edward and Cate, Soscha C. Ten and Yaxley, Page and Her, Jiwoong and Guillaumin, Julien}, year={2023}, month={Aug} } @article{pouzot-nevoret_hocine_allaouchiche_her_2023, title={Use of high-flow oxygen therapy in a cat with cardiogenic pulmonary edema}, url={https://doi.org/10.1177/20551169231195767}, DOI={10.1177/20551169231195767}, abstractNote={A 7-month-old female spayed domestic shorthair cat was presented for respiratory distress due to cardiogenic pulmonary edema. Despite initial treatment and oxygen delivery in an oxygen tent, the cat still showed signs of severe respiratory effort and oxygen saturation measured via pulse oximetry was below 85%. Because the owners declined mechanical ventilation, the cat was transitioned to high-flow oxygen therapy (HFOT). HFOT allowed significant improvement of the respiration parameters within 15 mins without causing clinical complications. The cat was briefly anaesthetised for the placement of the nasal cannula on initiation of HFOT, and the interface was well tolerated thereafter. The cat was transitioned to an oxygen cage after 16 h, weaned from oxygen 4 h later and was discharged after 3 days of hospitalisation. Long-term follow-up showed no abnormalities, and the leading hypothesis was transient myocardial thickening.The first use of HFOT in a dyspneic cat is described in this study. HFOT could be a life-saving option for cats with severe hypoxemia or do-not-intubate orders that fail to respond to conventional oxygen therapies.}, journal={Journal of Feline Medicine and Surgery Open Reports}, author={Pouzot-Nevoret, Céline and Hocine, Leïla and Allaouchiche, Bernard and Her, Jiwoong}, year={2023}, month={Jul} } @inbook{her_2022, title={Anesthesia/Perioperative Fluid Considerations}, DOI={10.1079/9781789243406.0008e}, booktitle={Small Animal Fluid Therapy}, publisher={CABI}, author={Her, Jiwoong}, year={2022}, month={Dec}, pages={115–118} } @inbook{her_2022, title={Impact of Heart Disease on Fluid Therapy}, DOI={10.1079/9781789243406.0008c}, booktitle={Small Animal Fluid Therapy}, publisher={CABI}, author={Her, Jiwoong}, year={2022}, month={Dec}, pages={107–109} } @inbook{her_2022, title={Maintenance Fluid Therapy}, DOI={10.1079/9781789243406.0006c}, booktitle={Small Animal Fluid Therapy}, publisher={CABI}, author={Her, Jiwoong}, year={2022}, month={Dec}, pages={63–67} } @book{cooper_guillaumin_yaxley_her_young_2022, title={Small Animal Fluid Therapy}, DOI={10.1079/9781789243406.0000}, publisher={CABI}, author={Cooper, Edward and Guillaumin, Julien and Yaxley, Page and Her, Jiwoong and Young, Anda}, year={2022}, month={Dec} } @article{her_merbl_gerken_kim_hofmeister_bacek_kuo_yanke_2022, title={Relationship between admission vitals and brain herniation in 32 cats: a retrospective study}, url={https://doi.org/10.1177/1098612X211048639}, DOI={10.1177/1098612X211048639}, abstractNote={Objectives The aim of the study was to evaluate whether any admission vitals correlated with the presence of brain herniation diagnosed via MRI in cats presenting with neurologic signs. Methods Medical records at two veterinary university referral centers were reviewed to identify cats that underwent brain MRI between 2010 and 2019. A control group of cats with intracranial lesions without concurrent brain herniation was analyzed for comparison. Data relating to signalment, vitals on admission, abnormalities observed on initial neurologic examination, underlying etiology, advanced imaging findings and outcome were reviewed. A Modified Glasgow Coma Scale (MGCS) score was determined retrospectively based on initial neurologic examination. Logistic regressions were performed to investigate the relationship between each risk factor and the odds of brain herniation as diagnosed on MRI. Results Thirty-two cats with brain herniation and 44 cats with abnormal brain MRI without evidence of herniation (as a control group) based on MRI findings were included. Cats with intracranial neoplasia vs other diagnoses were found to be at increased risk of herniation (odds ratio [OR] 4.8, 95% confidence interval [CI] 1.8–13.8; P = 0.001). The odds of herniation increased with age (OR 1.1, 95% CI 1.01–1.2; P = 0.031). Cats with herniation had a significantly lower level of consciousness in their MGCS score ( P <0.0001) than cats without herniation. There was no significant difference in either motor activity or brainstem reflexes between the groups ( P >0.05). Conclusions and relevance Admission heart rate and blood pressure were not associated with brain herniation. Cats with herniation were presented with a significantly lower level of consciousness in their MGCS score; however, this clinical feature cannot be directly attributable to and predictive of herniation. Older cats with intracranial neoplasia are more likely to have brain herniation.}, journal={Journal of Feline Medicine and Surgery}, author={Her, Jiwoong and Merbl, Yael and Gerken, Katherine and Kim, Minjeong and Hofmeister, Erik and Bacek, Lenore M and Kuo, Kendon W and Yanke, Amy B}, year={2022}, month={Aug} } @article{her_yanke_gerken_yoon_peters_hofmeister_bacek_kuo_2022, title={Retrospective evaluation of the relationship between admission variables and brain herniation in dogs (2010–2019): 54 cases}, volume={32}, url={https://doi.org/10.1111/vec.13147}, DOI={10.1111/vec.13147}, abstractNote={To document the admission systolic blood pressure (SBP), heart rate (HR), and modified Glasgow coma scale (MGCS) score in dogs with and without brain herniation and to determine their relationship with brain herniation.Retrospective study between 2010 and 2019.University veterinary teaching hospital.Fifty-four client-owned dogs with brain herniation and 40 client-owned dogs as a control group, as determined on magnetic resonance imaging.None.SBP, HR, MGCS score, and outcome were extracted from medical records. MGCS score was retrospectively calculated based on initial neurological examination in dogs with adequate available information. Dogs with brain herniation had a significantly higher SBP (P = 0.0078), greater SBP-HR difference (P = 0.0006), and lower MGCS score (P < 0.0001) compared to control dogs. A cutoff value of an SBP ≥ 178 mm Hg, SBP-HR ≥ 60, and MGCS score ≤ 14 each provides a specificity of 90%-98%. A combination of an SBP > 140 mm Hg and HR < 80/min provided 24% sensitivity and 100% specificity to diagnose dogs with brain herniation (P < 0.0001).A high SBP, a greater difference between SBP and HR, a combination of higher SBP and lower HR, and a low MGCS score were associated with brain herniation in dogs presenting with neurological signs upon admission. Early recognition of these abnormalities may help veterinarians to suspect brain herniation and determine timely treatment.}, number={1}, journal={Journal of Veterinary Emergency and Critical Care}, publisher={Wiley}, author={Her, Jiwoong and Yanke, Amy B. and Gerken, Katherine and Yoon, Jin and Peters, Ashley Antonia and Hofmeister, Erik and Bacek, Lenore M. and Kuo, Kendon W.}, year={2022}, month={Jan}, pages={50–57} } @article{her_kuo_winter_cruz-espindola_bacek_boothe_2020, title={Pharmacokinetics of Pimobendan and Its Metabolite O-Desmethyl-Pimobendan Following Rectal Administration to Healthy Dogs}, url={http://dx.doi.org/10.3389/fvets.2020.00423}, DOI={10.3389/fvets.2020.00423}, abstractNote={Objective: To describe the pharmacokinetics of parent pimobendan (PIM) and its active metabolite, o-desmethyl-pimobendan (ODMP), after oral and rectal administration of pimobendan to healthy dogs. Animals: 8 healthy privately-owned dogs. Procedures: Dogs received a single dose (0.5 mg/kg) of a commercially available pimobendan tablet per os (PO). Twelve blood samples were collected over a 12-hour period for pharmacokinetic analysis. After 24 hours washout period, dogs received the same dose of a pimobendan solution per rectum (PR), and samples were obtained at the same times for analysis. Results: For PIM, PO vs PR, respectively, mean maximum plasma concentration (Cmax, ng/mL) 49.1 ± 28.7 vs 10.1 ± 2, time to reach the maximum concentration (Tmax, h) 2.1 ± 0.9 vs 1 ± 0.4, disappearance half-life (t1/2, h) 1.8 ± 0.8 vs 2.2 ± 0.6, and area under the concentration-time curve (AUC, ng*h/mL), 148.4 ± 71.6 vs 31.1 ± 11.9, with a relative bioavailability (F, %) of 25 ± 8. For ODMP, PO vs PR, respectively, Cmax was 30.9 ± 10.4 vs 8.8 ± 4.8, Tmax 3.2 ± 1.6 vs 1.7 ± 1.1, t1/2 5.0 ± 2.7 vs 8.3 ± 4.8, with AUC 167.8 ± 36.2 vs 50.1 ± 19.2, with F of 28 ± 6. Differences between PO and PR were significant (P < 0.03) for AUC and Cmax for both PIM and ODMP. Conclusions and Clinical Relevance: Pharmacokinetics of PIM and ODMP were described following PO and PR administration. Findings suggest that pimobendan PR might achieve effective concentrations and as such warrant future studies of clinical effectiveness in treating dogs with congestive heart failure who are unable to receive medication PO.}, journal={Frontiers in Veterinary Science}, author={Her, Jiwoong and Kuo, Kendon W. and Winter, Randolph L. and Cruz-Espindola, Crisanta and Bacek, Lenore M. and Boothe, Dawn M.}, year={2020}, month={Aug} } @article{lee_jung_kim_kim_park_kang_her_jeong_so_yoon_2017, title={Porcine ear necrosis syndrome by coinfection of porcine reproductive and respiratory syndrome virus and Staphylococcus hyicus}, volume={57}, DOI={10.14405/kjvr.2017.57.2.143}, abstractNote={Porcine ear necrosis syndrome is characterized by erosive and ulcerative lesions at the margin or tip of the pinna.Three growing pigs of different ages exhibited retarded growth accompanied by reddening and necrosis of ear prior to death.Gross examination showed reddening, swelling, black discoloration, scaling, and variable-sized yellowish materials and edema in ear cross section.Microscopically, thrombosis, abscess, ulceration, epidermal hyperplasia, and dermal pyogranulomatous inflammation with an intralesional bacterial colony were observed.Staphylococcus hyicus was isolated in all pigs' ears and porcine reproductive and respiratory syndrome virus was detected by PCR and immunohistochemistry.}, number={2}, journal={Korean Journal of Veterinary Research}, publisher={The Korean Society of Veterinary Science (KJVR)}, author={Lee, Seunghee and Jung, Ji-Youl and Kim, Seong-Hee and Kim, Jong-Wan and Park, Jung-Won and Kang, Dae-Young and Her, Ji-Woong and Jeong, Yea-Ji and So, Byung Jae and Yoon, Soon-Seek}, year={2017}, month={Jun}, pages={143–146} } @article{jung_her_jeong_ku_choi_so_yoon_2015, title={A case of malignant dysgerminoma in a slaughtered dairy cow}, volume={55}, DOI={10.14405/kjvr.2015.55.2.149}, number={2}, journal={Korean Journal of Veterinary Research}, publisher={The Korean Society of Veterinary Science (KJVR)}, author={Jung, Ji-Youl and Her, Ji-Woong and Jeong, Yea-Ji and Ku, Kyung-Nyer and Choi, Kwon-Rac and So, Byung-Jae and Yoon, Soon-Seek}, year={2015}, month={Jun}, pages={149–152} } @article{jeong_jung_her_baek_lee_lee_yoon_2015, title={Congenital systemic melanosis in a black mongrel pig}, volume={55}, url={http://dx.doi.org/10.14405/kjvr.2015.55.2.145}, DOI={10.14405/kjvr.2015.55.2.145}, abstractNote={(Received: January 9, 2015; Revised: May 4, 2015; Accepted: May 11, 2015)Abstract : Four 3-day-old piglets with retarded growth were submitted to the Animal and Plant Quarantine Agencyfor diagnosis. Necropsy showed that one piglet had black spots ranging from 2 mm to 1 cm in diameter in thecerebellum, lungs, regional lymph nodes, and cecum. Histological findings were consistent with the gross appearancein which melanin pigmentation was observed in the organs mentioned above. Based on Fontana-Masson staining, wediagnosed this animal with systemic melanosis. To the best of our knowledge, this is the first case of systemic melanosisin black breeds of swine in Korea. Keywords: black pig, Fontana-Masson staining, melanosis, melanin}, number={2}, journal={Korean Journal of Veterinary Research}, publisher={The Korean Society of Veterinary Science (KJVR)}, author={Jeong, Yea-Ji and Jung, Ji-Youl and Her, Ji-Woong and Baek, Kang-Hyun and Lee, Jong-Hyeong and Lee, Myoung-Heon and Yoon, Soon-Seek}, year={2015}, month={Jun}, pages={145–148} } @article{rhyoo_jung_her_lee_ku_choi_yoon_2014, title={Epitheliogenesis imperfecta in a bovine fetus of Korean native cattle}, volume={54}, DOI={10.14405/kjvr.2014.54.4.253}, number={4}, journal={Korean Journal of Veterinary Research}, publisher={The Korean Society of Veterinary Science (KJVR)}, author={Rhyoo, Moon-Young and Jung, Ji-Youl and Her, Ji-Woong and Lee, Myoung-Heon and Ku, Kyung-Nyer and Choi, Kwon-Rac and Yoon, Soon-Seek}, year={2014}, month={Dec}, pages={253–256} } @article{baek_lee_lee_kim_park_lee_her_lee_bae_2014, title={Fatal cryptosporidiosis in a calf}, volume={54}, DOI={10.14405/kjvr.2014.54.4.257}, number={4}, journal={Korean Journal of Veterinary Research}, publisher={The Korean Society of Veterinary Science (KJVR)}, author={Baek, Kang-Hyun and Lee, Hyun-Kyoung and Lee, Kyung-Hyun and Kim, Ha-Young and Park, Jung-Won and Lee, Bo-Ram and Her, Ji-Woong and Lee, Myoung-Heon and Bae, You-Chan}, year={2014}, month={Dec}, pages={257–260} } @article{rhyoo_jung_lee_her_bae_lee_baek_lee_jean_kim_et al._2013, title={Case report of Johne's disease in Korean black goat (Capra hircus aegagrus)}, volume={53}, DOI={10.14405/kjvr.2013.53.4.273}, abstractNote={Two Korean black goat (approx. 2 and 3 years old) showing diarrhea and chronic weight loss were submitted to Animal and Plant Quarantine Agency.At necropsy, there were thickening of small intestine and enlargement of mesenteric lymph nodes.Microscopically, they had granulomatous enteritis in the small and large intestine and granulomatous lymphadenitis.By polymerase chain reaction (PCR) and acid fast stain, strong positive reaction and acid-fast rod bacteria were detected.According to the result of histopathology and PCR, we confirmed this case as Johne's disease.As far as we know, this is the first report of Johne's disease in Korean black goat.}, number={4}, journal={Korean Journal of Veterinary Science}, publisher={The Korean Society of Veterinary Science (KJVR)}, author={Rhyoo, Moon-Young and Jung, Ji-Youl and Lee, Kyung-Hyun and Her, Ji-Woong and Bae, You-Chan and Lee, Hyun-Kyoung and Baek, Kang-Hyun and Lee, Bo-Ram and Jean, Young-Hwa and Kim, Jae-Myung and et al.}, year={2013}, month={Dec}, pages={273–276} }