Jared Hopkins

College of Engineering

Works (1)

Updated: July 5th, 2023 15:21

2019 journal article

ULTRASOUND-STIMULATED PHASE-CHANGE CONTRAST AGENTS FOR TRANSEPITHELIAL DELIVERY OF MACROMOLECULES, TOWARD GASTROINTESTINAL DRUG DELIVERY

ULTRASOUND IN MEDICINE AND BIOLOGY, 45(7), 1762–1776.

By: S. Fix *, B. Koppolu n, A. Novell *, J. Hopkins n, T. Kierski  n, D. Zaharoff n, P. Dayton n, V. Papadopoulou  n

author keywords: Ultrasound; Transepithelial delivery; Acoustic droplet vaporization; Phase-change contrast agents; Nanodroplet
MeSH headings : Cells, Cultured; Contrast Media; Dextrans / administration & dosage; Drug Delivery Systems / methods; Fluorescein-5-isothiocyanate / administration & dosage; Fluorescein-5-isothiocyanate / analogs & derivatives; Gastrointestinal Agents / administration & dosage; Humans; Image Enhancement / methods; In Vitro Techniques; Ultrasonography / methods
TL;DR: It is demonstrated that ultrasound-stimulated phase change contrast agents (PCCAs) can transiently disrupt confluent colorectal adenocarcinoma monolayers and improve the transepithelial transport of a macromolecular model drug. (via Semantic Scholar)
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Source: Web Of Science
Added: June 24, 2019

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