Works (20)

Updated: September 10th, 2023 05:02

2022 journal article

Triptorelin-functionalized PEG-coated biosynthesized gold nanoparticles: Effects of receptor-ligand interactions on adhesion to triple negative breast cancer cells

Biomaterials Advances, 4, 212801.

By: V. Uzonwanne*, A. Navabi*, J. Obayemi *, J. Hu* , A. Salifu*, S. Ghahremani*, N. Ndahiro*, N. Rahbar *, W. Soboyejo *

co-author countries: United States of America 🇺🇸
author keywords: Adhesion; PEG-coated gold nanoparticles; Molecular dynamic simulation; Triptorelin; AFM; Triple negative breast cancer
MeSH headings : Cell Line, Tumor; Gold / pharmacology; Humans; Ligands; Metal Nanoparticles; Triple Negative Breast Neoplasms / drug therapy; Triptorelin Pamoate / pharmacology
Source: ORCID
Added: August 10, 2022

2021 journal article

Actin cytoskeletal structure and the statistical variations of the mechanical properties of non-tumorigenic breast and triple-negative breast cancer cells

Journal of the Mechanical Behavior of Biomedical Materials, 119, 104505.

By: K. Onwudiwe *, J. Hu* , J. Obayemi *, V. Uzonwanne*, C. Ani*, C. Nwazojie*, C. Onyekanne*, T. Ezenwafor*, O. Odusanya*, W. Soboyejo *

co-author countries: Nigeria 🇳🇬 United States of America 🇺🇸
author keywords: Shear assay technique; Actin cytoskeleton; Viscoelastic properties; Statistical variations
MeSH headings : Actins; Cytoskeleton; Elastic Modulus; Humans; Triple Negative Breast Neoplasms; Viscosity
Source: ORCID
Added: August 10, 2022

2021 article

Investigation of creep properties and the cytoskeletal structures of non-tumorigenic breast cells and triple-negative breast cancer cells

Onwudiwe, K., Obayemi, J., Hu, J., Oparah, J., Onyekanne, C., Nwazojie, C., … Soboyejo, W. (2021, December 29). JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, Vol. 110.

By: K. Onwudiwe *, J. Obayemi *, J. Hu n , J. Oparah*, C. Onyekanne*, C. Nwazojie*, T. Aina*, V. Uzonwanne*, A. Salifu*, W. Soboyejo *

co-author countries: Nigeria 🇳🇬 United States of America 🇺🇸
author keywords: cancer detection; cell viscoelastic; creep properties; confocal microscopy; cytoskeletal proteins; immunofluorescence staining; relative volume density; shear assay
MeSH headings : Actins; Cytoskeleton; Elastic Modulus; Elasticity; Humans; Triple Negative Breast Neoplasms; Viscosity
Sources: ORCID, Web Of Science
Added: January 10, 2022

2021 journal article

Percutaneous liquid ablation agent for tumor treatment and drug delivery

Science Translational Medicine, 13(580).

By: H. Albadawi*, Z. Zhang*, I. Altun *, J. Hu* , L. Jamal *, K. Ibsen*, E. Tanner *, S. Mitragotri *, R. Oklu *

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Carcinoma, Hepatocellular / drug therapy; Humans; Liver Neoplasms / drug therapy; Liver Transplantation; Pharmaceutical Preparations; Rabbits; Treatment Outcome
Source: ORCID
Added: August 10, 2022

2021 journal article

Silk Embolic Material for Catheter‐Directed Endovascular Drug Delivery

Advanced Materials, 11, 2106865.

By: J. Hu* , H. Albadawi*, Z. Zhang*, M. Salomao *, S. Gunduz*, S. Rehman*, L. D’Amone *, J. Mayer*, F. Omenetto *, R. Oklu *

co-author countries: United States of America 🇺🇸
author keywords: embolization; immunotherapy; nanoclay; silk; vascular interventions
MeSH headings : Animals; Arteries; Catheters; Cattle; Drug Delivery Systems; Embolization, Therapeutic / methods; Silk; Swine
Source: ORCID
Added: August 10, 2022

2020 journal article

Bioactive‐Tissue‐Derived Nanocomposite Hydrogel for Permanent Arterial Embolization and Enhanced Vascular Healing

Advanced Materials.

By: J. Hu* , I. Altun *, Z. Zhang*, H. Albadawi*, M. Salomao *, J. Mayer*, L. Hemachandra*, S. Rehman*, R. Oklu *

co-author countries: United States of America 🇺🇸
author keywords: decellularized extracellular matrix; embolization; hybrid nanocomposite hydrogels; transcatheter delivery; vascular remodeling
MeSH headings : Animals; Arteries / drug effects; Arteries / pathology; Arteries / physiopathology; Biocompatible Materials / chemistry; Biocompatible Materials / pharmacology; Embolization, Therapeutic / methods; Extracellular Matrix / chemistry; Hydrogels / chemistry; Nanocomposites / chemistry; Shear Strength; Swine; Vascular Remodeling / drug effects
Source: ORCID
Added: August 10, 2022

2020 journal article

Blood‐Derived Biomaterial for Catheter‐Directed Arterial Embolization

Advanced Materials.

By: I. Altun *, J. Hu* , H. Albadawi*, Z. Zhang*, M. Salomao, J. Mayer*, L. Jamal *, R. Oklu *

co-author countries: United States of America 🇺🇸
author keywords: angiography; biomaterials; embolization; platelet rich fibrin; point‐ of‐ care
MeSH headings : Animals; Arteries; Biocompatible Materials / pharmacology; Blood; Catheters; Cell Proliferation / drug effects; Embolization, Therapeutic / instrumentation; Neovascularization, Physiologic / drug effects; Swine
Source: ORCID
Added: August 10, 2022

2020 journal article

Emerging embolic agents in endovascular embolization: an overview

Progress in Biomedical Engineering, 2(1), 012003.

By: C. Wang*, J. Hu* , R. Sheth * & R. Oklu *

co-author countries: United States of America 🇺🇸
author keywords: minimally invasive procedures; embolic agents; transcatheter delivery; translational applications
Source: ORCID
Added: August 10, 2022

2020 book review

Foundations of Biomaterials Engineering by Maria Cristina Tanzi, Silvia Farè, and Gabriele Candiani

[Review of]. MRS Bulletin.

Source: ORCID
Added: August 10, 2022

2020 journal article

Luteinizing Hormone-Releasing Hormone (LHRH) Conjugated Magnetite Nanoparticles as MRI Contrast Agents for Breast Cancer Imaging

Applied Sciences, 10(15), 5175.

By: J. Hu* , J. Obayemi *, K. Malatesta*, E. Yurkow*, D. Adler* & W. Soboyejo *

co-author countries: United States of America 🇺🇸
author keywords: triple negative breast cancer (TNBC); luteinizing hormone-releasing hormone (LHRH); magnetite nanoparticles; magnetic resonance imaging (MRI); cancer detection
Source: ORCID
Added: August 10, 2022

2020 journal article

Nanocomposite Hydrogel with Tantalum Microparticles for Rapid Endovascular Hemostasis

Advanced Science, n/a(n/a), 2003327.

By: H. Albadawi*, I. Altun *, J. Hu* , Z. Zhang*, A. Panda*, H. Kim *, A. Khademhosseini *, R. Oklu *

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: August 10, 2022

2019 journal article

A shear assay study of single normal/breast cancer cell deformation and detachment from poly-di-methyl-siloxane (PDMS) surfaces

Journal of the Mechanical Behavior of Biomedical Materials, 91, 76–90.

By: C. Ani*, J. Obayemi *, V. Uzonwanne*, Y. Danyuo *, O. Odusanya, J. Hu* , K. Malatesta*, W. Soboyejo *

co-author countries: Ghana 🇬🇭 Nigeria 🇳🇬 United States of America 🇺🇸
author keywords: Cell deformation and detachment; Shear assay technique; Viscoelastic cell deformation; Vinculin pull-out; Interfacial fracture
MeSH headings : Biomechanical Phenomena; Breast / cytology; Breast / pathology; Breast Neoplasms / pathology; Cell Adhesion; Cell Line, Tumor; Cytoskeleton / metabolism; Dimethylpolysiloxanes; Elasticity; Humans; Hydrodynamics; Nylons; Shear Strength; Surface Properties; Viscosity
Source: ORCID
Added: August 10, 2022

2019 journal article

Advances in Biomaterials and Technologies for Vascular Embolization

Advanced Materials.

By: J. Hu* , H. Albadawi*, B. Chong*, A. Deipolyi *, R. Sheth *, A. Khademhosseini *, R. Oklu *

co-author countries: United States of America 🇺🇸
author keywords: catheter-based delivery; embolic agents; interventional radiology; minimally invasive surgery; vascular embolization
MeSH headings : Animals; Biocompatible Materials / chemistry; Embolization, Therapeutic / instrumentation; Embolization, Therapeutic / methods; Endovascular Procedures; Humans; Metals / chemistry; Microspheres; Polymers / chemistry
Source: ORCID
Added: August 10, 2022

2019 journal article

Compressive Deformation and Failure of Trabecular Structures in A Turtle Shell

Acta Biomaterialia.

author keywords: Turtle shell; Trabecular bone; Compressive deformation; Failure; Foam structure
MeSH headings : Animal Shells / chemistry; Animal Shells / diagnostic imaging; Animals; Porosity; Stress, Mechanical; Turtles / anatomy & histology; X-Ray Microtomography
Source: ORCID
Added: August 10, 2022

2018 journal article

An investigation of the viscoelastic properties and the actin cytoskeletal structure of triple negative breast cancer cells

Journal of the Mechanical Behavior of Biomedical Materials, 86, 1–13.

co-author countries: United States of America 🇺🇸
author keywords: Shear assay method; Digital image correlation; Cell viscoelasticity; Actin cytoskeletal structure; Cancer diagnosis
MeSH headings : Actin Cytoskeleton / metabolism; Biomechanical Phenomena; Cell Line, Tumor; Elasticity; Humans; Neoplasm Metastasis; Triple Negative Breast Neoplasms / pathology; Viscosity
Source: ORCID
Added: August 10, 2022

2018 journal article

Enhanced cellular uptake of LHRH-conjugated PEG-coated magnetite nanoparticles for specific targeting of triple negative breast cancer cells

Materials Science and Engineering C, 88, 32–45.

By: J. Hu* , J. Obayemi *, K. Malatesta*, A. Ko?mrlj & W. Soboyejo *

co-author countries: United States of America 🇺🇸

Contributors: J. Hu* , J. Obayemi *, K. Malatesta*, A. Košmrlj * & W. Soboyejo *

author keywords: Luteinizing hormone releasing hormone (LHRH); LHRH-conjugated PEG-coated magnetite anoparticles (LHRH-MNPs); Triple negative breast cancer (TNBC); Specific targeting
MeSH headings : Cell Line, Tumor; Coated Materials, Biocompatible / chemistry; Coated Materials, Biocompatible / pharmacokinetics; Coated Materials, Biocompatible / pharmacology; Drug Delivery Systems / methods; Female; Gonadotropin-Releasing Hormone / chemistry; Gonadotropin-Releasing Hormone / pharmacokinetics; Gonadotropin-Releasing Hormone / pharmacology; Humans; Magnetite Nanoparticles / chemistry; Magnetite Nanoparticles / therapeutic use; Polyethylene Glycols / chemistry; Polyethylene Glycols / pharmacokinetics; Polyethylene Glycols / pharmacology; Triple Negative Breast Neoplasms / drug therapy; Triple Negative Breast Neoplasms / metabolism
Source: ORCID
Added: August 10, 2022

2018 journal article

Investigation of adhesive interactions in the specific targeting of Triptorelin-conjugated PEG-coated magnetite nanoparticles to breast cancer cells

Acta Biomaterialia, 71, 363–378.

co-author countries: United States of America 🇺🇸
author keywords: Triptorelin-conjugated PEG-coated; magnetite nanoparticles; Adhesive interaction; Atomic force microscopy; Molecular dynamics simulations; Breast cancer targeting
MeSH headings : Breast Neoplasms / drug therapy; Breast Neoplasms / metabolism; Breast Neoplasms / pathology; Coated Materials, Biocompatible / chemistry; Coated Materials, Biocompatible / pharmacokinetics; Coated Materials, Biocompatible / pharmacology; Drug Delivery Systems; Female; Humans; Magnetite Nanoparticles / chemistry; Magnetite Nanoparticles / therapeutic use; Polyethylene Glycols / chemistry; Polyethylene Glycols / pharmacokinetics; Polyethylene Glycols / pharmacology; Triptorelin Pamoate / chemistry; Triptorelin Pamoate / pharmacokinetics; Triptorelin Pamoate / pharmacology
Source: ORCID
Added: August 10, 2022

2017 journal article

Adhesion of ligand-conjugated biosynthesized magnetite nanoparticles to triple negative breast cancer cells

Journal of the Mechanical Behavior of Biomedical Materials, 68, 276–286.

By: J. Obayemi *, J. Hu* , V. Uzonwanne*, O. Odusanya*, K. Malatesta*, N. Anuku*, W. Soboyejo *

co-author countries: Nigeria 🇳🇬 United States of America 🇺🇸

Contributors: J. Obayemi *, J. Hu* , V. Uzonwanne*, O. Odusanya*, K. Malatesta*, N. Anuku*, W. Soboyejo *

author keywords: Chemically synthesized magnetite nanoparticles (CMNPs); Biosynthesized magnetite nanoparticles (BMNPs); Luteinizing hormone-releasing hormone (LHRH); Breast specific antibody (BSA); Ephrin type-A receptor 2 (EphA2)
MeSH headings : Adhesiveness; Cell Line, Tumor; Drug Delivery Systems; Gonadotropin-Releasing Hormone / chemistry; Humans; Magnetite Nanoparticles / chemistry; Nanoconjugates / chemistry; Receptor, EphA2 / chemistry; Triple Negative Breast Neoplasms / metabolism
Source: ORCID
Added: August 10, 2022

2017 journal article

Biosynthesis of Gold Nanoparticles and Gold/Prodigiosin Nanoparticles with Serratia marcescens Bacteria

Waste and Biomass Valorization, 8(6), 2045–2059.

By: S. Dozie-Nwachukwu*, J. Obayemi *, Y. Danyuo *, G. Etuk-Udo, Y. Chi, J. Hu* , N. Anuku, O. Odusanya*, K. Malatesta, W. Soboyejo *

co-author countries: Nigeria 🇳🇬

Contributors: S. Dozie-Nwachukwu*, J. Obayemi *, Y. Danyuo *, G. Etuk-Udo, Y. Chi, J. Hu* , N. Anuku, O. Odusanya*, K. Malatesta, W. Soboyejo *

author keywords: Serratia marcescens; Gold nanoparticles; Cell-free extract; Biomass; Dynamic light scattering; Prodigiosin
Source: ORCID
Added: August 10, 2022

2017 conference paper

Precision control of nanoparticle monolayer assembly: Optimizing rate and crystal quality

2017 IEEE 17th International Conference on Nanotechnology, NANO 2017, 286–289.

By: M. Bedewy *, J. Hu*  & A. Hart *

co-author countries: United States of America 🇺🇸

Contributors: M. Bedewy *, J. Hu*  & A. Hart *

Source: ORCID
Added: August 10, 2022

Employment

Updated: August 30th, 2021 16:15

2021 - present

North Carolina State University Raleigh, North Carolina, US
Assistant Professor Mechanical and Aerospace Engineering

2018 - present

Mayo Clinic Arizona Scottsdale, AZ, US
Postdoctoral Research Fellow Department of Radiology

Education

Updated: June 21st, 2018 11:34

2013 - 2018

Princeton University Princeton, NJ, US
Ph.D. Mechanical and Aerospace Engineering

2009 - 2013

University of Michigan Ann Arbor, MI, US
B.S.E Mechanical Engineering