Works (2)

Updated: July 5th, 2023 15:48

2011 journal article

Genetic analysis of complex traits in the emerging Collaborative Cross

GENOME RESEARCH, 21(8), 1213–1222.

By: D. Aylor*, W. Valdar*, W. Foulds-Mathes*, R. Buus*, R. Verdugo*, R. Baric*, M. Ferris*, J. Frelinger* ...

MeSH headings : Animals; Crosses, Genetic; Female; Gene Expression; Genetic Association Studies; Genome; Haplotypes; Male; Mice; Phenotype; Quantitative Trait Loci
TL;DR: It is demonstrated that the genetic diversity of the CC, which derives from random mixing of eight founder strains, results in high phenotypic diversity and enhances the ability to map causative loci underlying complex disease-related traits. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Genetic mapping and developmental timing of transmission ratio distortion in a mouse interspecific backcross


By: C. Eversley*, T. Clark*, Y. Xie*, J. Steigerwalt*, T. Bell*, F. Villena*, D. Threadgill n

MeSH headings : Alleles; Animals; Chromosome Mapping; Female; Genotype; Hybridization, Genetic; Inheritance Patterns; Male; Mice / genetics; Mice, Inbred A; Microsatellite Repeats; Models, Genetic
TL;DR: The results are consistent with the TRD mechanism being deviation from Mendelian inheritance rather than meiotic drive or segregation distortion, and the underlying causes for the interspecific TRD events are the differential post-natal survival of pups with specific genotypes. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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