Works (5)
Updated: July 5th, 2023 15:39
2018 journal article
A novel integrated strategy for the detection and quantification of the neurotoxin beta-N-methylamino-l-alanine in environmental samples
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 410(10), 2597–2605.
author keywords: BMAA; CZE; Isomer separation; Quantification; HRAM MS/MS; Seafood
MeSH headings : Amino Acids, Diamino / analysis; Animals; Cyanobacteria Toxins; Environmental Monitoring / methods; Environmental Pollutants / analysis; Fishes / metabolism; Food Analysis / methods; Humans; Limit of Detection; Neurotoxins / analysis; Seafood / analysis; Tandem Mass Spectrometry / methods
TL;DR:
Interestingly, BMAA was not identified in the free protein fraction but only detected after protein hydrolysis which suggests that BMAA is tightly bound by and/or incorporated into proteins.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2018 journal article
Machine Learning Reveals Protein Signatures in CSF and Plasma Fluids of Clinical Value for ALS
SCIENTIFIC REPORTS, 8(1).
Contributors: M. Bereman n, n, J. Enders n & T. Nash n
MeSH headings : Amyotrophic Lateral Sclerosis / blood; Amyotrophic Lateral Sclerosis / cerebrospinal fluid; Amyotrophic Lateral Sclerosis / metabolism; Humans; Machine Learning; Multivariate Analysis; Proteomics
TL;DR:
The potential of a panel of targeted proteins for objective measurements of clinical value in ALS is demonstrated, and three proteins composed a prognostic model that explained 49% of the variation in the ALS-FRS scores.
(via Semantic Scholar)
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
10. Reduced Inequalities
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 19, 2018
2017 journal article
Exposure to BMAA mirrors molecular processes linked to neurodegenerative disease
Proteomics, 17(17-18).
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
An Automated Pipeline to Monitor System Performance in Liquid Chromatography-Tandem Mass Spectrometry Proteomic Experiments
JOURNAL OF PROTEOME RESEARCH, 15(12), 4763–4769.
author keywords: system suitability; process control; proteomics; tandem mass spectrometry; control charts
MeSH headings : Automation; Chromatography, Liquid / methods; Chromatography, Liquid / standards; Information Dissemination; Internet; Proteomics / methods; Tandem Mass Spectrometry / methods; Tandem Mass Spectrometry / standards; Workflow
TL;DR:
The development of a completely automated pipeline to monitor system suitability in bottom-up proteomic experiments, termed Panorama AutoQC, is reported, to evaluate LC-MS/MS performance in a range of scenarios including identification of suboptimal instrument performance, evaluation of ultrahigh pressure chromatography, and identification of the major sources of variation throughout years of peptide data collection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Reagent for Evaluating Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Performance in Bottom-Up Proteomic Experiments
ANALYTICAL CHEMISTRY, 87(23), 11635–11640.
MeSH headings : Amino Acids / chemistry; Chromatography, Liquid / methods; HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Indicators and Reagents / chemistry; Peptides / chemical synthesis; Peptides / chemistry; Proteomics / methods; Tandem Mass Spectrometry / methods
TL;DR:
A novel proteomic standard for assessing liquid chromatography-tandem mass spectrometry (LC-MS/MS) instrument performance, in terms of chromatographic reproducibility and dynamic range within a single LC- MS/MS injection, is presented.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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