Works (15)

Updated: July 5th, 2023 21:22

2012 journal article

Evaluation of the toxicity of 2-aminoimidazole antibiofilm agents using both cellular and model organism systems

DRUG AND CHEMICAL TOXICOLOGY, 35(3), 310โ€“315.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: 2-aminoimidazole; adjuvant; biofilm; Caenorhabditis elegans; toxicity; Toxicity of 2-aminoimidazole; antibiofilm agents
MeSH headings : Adjuvants, Pharmaceutic / toxicity; Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / toxicity; Biofilms / drug effects; Caenorhabditis elegans; Cell Line; Dose-Response Relationship, Drug; Environmental Exposure; Fertility / drug effects; Humans; Imidazoles / pharmacology; Imidazoles / toxicity; Keratinocytes / metabolism; Tetrazolium Salts; Thiazoles; Toxicity Tests
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Small molecule control of bacterial biofilms

Organic & Biomolecular Chemistry, 10(37), 7457โ€“7474.

By: R. Worthington, J. Richards & C. Melander

Source: NC State University Libraries
Added: August 6, 2018

2011 review

Anti-biofilm compounds derived from marine sponges

[Review of ]. Marine Drugs, 9(10), 2010โ€“2035.

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Identification of aryl 2-aminoimidazoles as biofilm inhibitors in Gram-negative bacteria

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 20(12), 3797โ€“3800.

By: C. Bunders n, J. Richards n & C. Melander n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: 2-Aminoimidazoles; Bacterial biofilms
MeSH headings : Acinetobacter baumannii / drug effects; Anti-Bacterial Agents / chemistry; Biofilms / drug effects; Escherichia coli / drug effects; Gram-Negative Bacteria / drug effects; Imidazoles / chemistry; Imidazoles / pharmacology; Plankton / drug effects; Pseudomonas aeruginosa / drug effects; Small Molecule Libraries / chemical synthesis
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Amide Isosteres of Oroidin: Assessment of Antibiofilm Activity and C. elegans Toxicity

JOURNAL OF MEDICINAL CHEMISTRY, 52(15), 4582โ€“4585.

By: J. Richards n, S. Reyes n, S. Stowe n, A. Tucker n, T. Ballard n, L. Mathies n, J. Cavanagh n, C. Melander n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Amides / chemical synthesis; Amides / pharmacology; Amides / toxicity; Animals; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Caenorhabditis elegans / drug effects; Pseudomonas aeruginosa / drug effects; Pseudomonas aeruginosa / physiology; Pyrroles / chemical synthesis; Pyrroles / pharmacology; Pyrroles / toxicity; Structure-Activity Relationship; Sulfonamides / chemical synthesis; Sulfonamides / pharmacology; Thiourea / chemical synthesis; Thiourea / pharmacology; Urea / chemical synthesis; Urea / pharmacology
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Antibiofilm Activity of a Diverse Oroidin Library Generated through Reductive Acylation

JOURNAL OF ORGANIC CHEMISTRY, 74(4), 1755โ€“1758.

By: T. Ballard n, J. Richards n, A. Aquino n, C. Reed n & C. Melander n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Acylation; Biofilms / drug effects; Oxidation-Reduction; Proteobacteria / drug effects; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / pharmacology; Small Molecule Libraries / chemical synthesis; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology
Source: Web Of Science
Added: August 6, 2018

2009 review

Controlling Bacterial Biofilms

[Review of ]. CHEMBIOCHEM, 10(14), 2287โ€“2294.

By: J. Richards n & C. Melander n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: bacteriophages; biofilms; drug discovery; natural products; quorum sensing
MeSH headings : Anti-Bacterial Agents / pharmacology; Bacteria / growth & development; Bacterial Physiological Phenomena; Bacteriophages / growth & development; Biofilms / growth & development; Biological Products / pharmacology; Drug Design; Quorum Sensing / physiology; Small Molecule Libraries
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Evaluation of dihydrooroidin as an antifouling additive in marine paint

INTERNATIONAL BIODETERIORATION & BIODEGRADATION, 63(4), 529โ€“532.

By: C. Melander n, P. Moeller*, T. Ballard n, J. Richards n, R. Huigens n & J. Cavanagh n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Antifouling; Biofilms; Natural products
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Effects of N-pyrrole substitution on the anti-biofilm activities of oroidin derivatives against Acinetobacter baumannii

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 18(15), 4325โ€“4327.

By: J. Richards n, C. Reed n & C. Melander n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: biofilm; inhibition; dispersion; marine natural products; oroidin
MeSH headings : Acinetobacter baumannii / drug effects; Acinetobacter baumannii / growth & development; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Biofilms / growth & development; Humans; Imidazoles / chemistry; Microbial Sensitivity Tests; Molecular Structure; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / pharmacology; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Inhibition and dispersion of Pseudomonas aeruginosa biofilms with reverse amide 2-aminoimidazole oroidin analogues

ORGANIC & BIOMOLECULAR CHEMISTRY, 6(8), 1356โ€“1363.

By: J. Richards n, T. Ballard n & C. Melander n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Biofilms / growth & development; Humans; Imidazoles / chemistry; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa / drug effects; Pseudomonas aeruginosa / growth & development; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / pharmacology; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Inhibition and dispersion of proteobacterial biofilms

Chemical Communications (Cambridge, England), (14), 1698โ€“1700.

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Synthesis and Antibiofilm Activity of a Second-Generation Reverse-Amide Oroidin Library: A Structure-Activity Relationship Study

CHEMISTRY-A EUROPEAN JOURNAL, 14(34), 10745โ€“10761.

By: T. Ballard n, J. Richards n, A. Wolfe n & C. Melander n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: amino acids; biological activity; drug design; medicinal chemistry; structure-activity relationships
MeSH headings : Acinetobacter baumannii / drug effects; Acinetobacter baumannii / growth & development; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Biofilms / growth & development; Drug Design; Imidazoles / chemistry; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa / drug effects; Pseudomonas aeruginosa / growth & development; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / pharmacology; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Synthesis and screening of an oroidin library against Pseudomonas aeruginosa biofilms

CHEMBIOCHEM, 9(8), 1267โ€“1279.

By: J. Richards n, T. Ballard n, R. Huigens n & C. Melander n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: biological activity; drug design; medicinal chemistry; natural products; structure-activity relationships
MeSH headings : Biofilms; Cross-Linking Reagents / chemistry; Databases, Factual; Drug Design; Drug Evaluation, Preclinical; Molecular Structure; Pseudomonas aeruginosa / drug effects; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / pharmacology; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Synthesis of a 2-aminoimidazole library for antibiofilm screening utilizing the Sonogashira reaction

JOURNAL OF ORGANIC CHEMISTRY, 73(13), 5191โ€“5193.

By: J. Richards n & C. Melander n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Bacteria / drug effects; Biofilms / drug effects; Combinatorial Chemistry Techniques; Imidazoles / chemical synthesis; Molecular Structure
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Inhibition of Pseudomonas aeruginosa biofilm formation with bromoageliferin analogues

Journal of the American Chemical Society, 129(22), 6966-.

By: R. Huigens, J. Richards, G. Parise, T. Ballard, W. Zeng, R. Deora, C. Melander

Source: NC State University Libraries
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Scienceยฉ and InCitesยฉ (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.