Justin J. Richards
Works (15)
Updated: July 5th, 2023 21:22
2012 journal article
Evaluation of the toxicity of 2-aminoimidazole antibiofilm agents using both cellular and model organism systems
DRUG AND CHEMICAL TOXICOLOGY, 35(3), 310–315.
author keywords: 2-aminoimidazole; adjuvant; biofilm; Caenorhabditis elegans; toxicity; Toxicity of 2-aminoimidazole; antibiofilm agents
MeSH headings : Adjuvants, Pharmaceutic / toxicity; Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / toxicity; Biofilms / drug effects; Caenorhabditis elegans; Cell Line; Dose-Response Relationship, Drug; Environmental Exposure; Fertility / drug effects; Humans; Imidazoles / pharmacology; Imidazoles / toxicity; Keratinocytes / metabolism; Tetrazolium Salts; Thiazoles; Toxicity Tests
europepmc.org (repository)
Source: Web Of Science
Added: August 6, 2018
2012 journal article
Small molecule control of bacterial biofilms
Organic & Biomolecular Chemistry, 10(37), 7457–7474.
Source: NC State University Libraries
Added: August 6, 2018
2011 review
Anti-biofilm compounds derived from marine sponges
[Review of ]. Marine Drugs, 9(10), 2010–2035.
Source: NC State University Libraries
Added: August 6, 2018
2010 journal article
Identification of aryl 2-aminoimidazoles as biofilm inhibitors in Gram-negative bacteria
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 20(12), 3797–3800.
author keywords: 2-Aminoimidazoles; Bacterial biofilms
MeSH headings : Acinetobacter baumannii / drug effects; Anti-Bacterial Agents / chemistry; Biofilms / drug effects; Escherichia coli / drug effects; Gram-Negative Bacteria / drug effects; Imidazoles / chemistry; Imidazoles / pharmacology; Plankton / drug effects; Pseudomonas aeruginosa / drug effects; Small Molecule Libraries / chemical synthesis
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Amide Isosteres of Oroidin: Assessment of Antibiofilm Activity and C. elegans Toxicity
JOURNAL OF MEDICINAL CHEMISTRY, 52(15), 4582–4585.
MeSH headings : Amides / chemical synthesis; Amides / pharmacology; Amides / toxicity; Animals; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Caenorhabditis elegans / drug effects; Pseudomonas aeruginosa / drug effects; Pseudomonas aeruginosa / physiology; Pyrroles / chemical synthesis; Pyrroles / pharmacology; Pyrroles / toxicity; Structure-Activity Relationship; Sulfonamides / chemical synthesis; Sulfonamides / pharmacology; Thiourea / chemical synthesis; Thiourea / pharmacology; Urea / chemical synthesis; Urea / pharmacology
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Antibiofilm Activity of a Diverse Oroidin Library Generated through Reductive Acylation
JOURNAL OF ORGANIC CHEMISTRY, 74(4), 1755–1758.
MeSH headings : Acylation; Biofilms / drug effects; Oxidation-Reduction; Proteobacteria / drug effects; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / pharmacology; Small Molecule Libraries / chemical synthesis; Small Molecule Libraries / chemistry; Small Molecule Libraries / pharmacology
Source: Web Of Science
Added: August 6, 2018
2009 review
Controlling Bacterial Biofilms
[Review of ]. CHEMBIOCHEM, 10(14), 2287–2294.
author keywords: bacteriophages; biofilms; drug discovery; natural products; quorum sensing
MeSH headings : Anti-Bacterial Agents / pharmacology; Bacteria / growth & development; Bacterial Physiological Phenomena; Bacteriophages / growth & development; Biofilms / growth & development; Biological Products / pharmacology; Drug Design; Quorum Sensing / physiology; Small Molecule Libraries
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Evaluation of dihydrooroidin as an antifouling additive in marine paint
INTERNATIONAL BIODETERIORATION & BIODEGRADATION, 63(4), 529–532.
author keywords: Antifouling; Biofilms; Natural products
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Effects of N-pyrrole substitution on the anti-biofilm activities of oroidin derivatives against Acinetobacter baumannii
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 18(15), 4325–4327.
author keywords: biofilm; inhibition; dispersion; marine natural products; oroidin
MeSH headings : Acinetobacter baumannii / drug effects; Acinetobacter baumannii / growth & development; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Biofilms / growth & development; Humans; Imidazoles / chemistry; Microbial Sensitivity Tests; Molecular Structure; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / pharmacology; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Inhibition and dispersion of Pseudomonas aeruginosa biofilms with reverse amide 2-aminoimidazole oroidin analogues
ORGANIC & BIOMOLECULAR CHEMISTRY, 6(8), 1356–1363.
MeSH headings : Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Biofilms / growth & development; Humans; Imidazoles / chemistry; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa / drug effects; Pseudomonas aeruginosa / growth & development; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / pharmacology; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Inhibition and dispersion of proteobacterial biofilms
Chemical Communications (Cambridge, England), (14), 1698–1700.
Source: NC State University Libraries
Added: August 6, 2018
2008 journal article
Synthesis and Antibiofilm Activity of a Second-Generation Reverse-Amide Oroidin Library: A Structure-Activity Relationship Study
CHEMISTRY-A EUROPEAN JOURNAL, 14(34), 10745–10761.
author keywords: amino acids; biological activity; drug design; medicinal chemistry; structure-activity relationships
MeSH headings : Acinetobacter baumannii / drug effects; Acinetobacter baumannii / growth & development; Anti-Bacterial Agents / chemical synthesis; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Biofilms / drug effects; Biofilms / growth & development; Drug Design; Imidazoles / chemistry; Microbial Sensitivity Tests; Molecular Structure; Pseudomonas aeruginosa / drug effects; Pseudomonas aeruginosa / growth & development; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / pharmacology; Small Molecule Libraries; Stereoisomerism; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Synthesis and screening of an oroidin library against Pseudomonas aeruginosa biofilms
CHEMBIOCHEM, 9(8), 1267–1279.
author keywords: biological activity; drug design; medicinal chemistry; natural products; structure-activity relationships
MeSH headings : Biofilms; Cross-Linking Reagents / chemistry; Databases, Factual; Drug Design; Drug Evaluation, Preclinical; Molecular Structure; Pseudomonas aeruginosa / drug effects; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / pharmacology; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018
2008 journal article
Synthesis of a 2-aminoimidazole library for antibiofilm screening utilizing the Sonogashira reaction
JOURNAL OF ORGANIC CHEMISTRY, 73(13), 5191–5193.
MeSH headings : Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacology; Bacteria / drug effects; Biofilms / drug effects; Combinatorial Chemistry Techniques; Imidazoles / chemical synthesis; Molecular Structure
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Inhibition of Pseudomonas aeruginosa biofilm formation with bromoageliferin analogues
Journal of the American Chemical Society, 129(22), 6966-.
Source: NC State University Libraries
Added: August 6, 2018
