Joanne L Tuohy

Works (3)

Updated: July 5th, 2023 15:41

2020 journal article

Local Administration of Carboplatin in Poloxamer 407 After an Ulnar Osteosarcoma Removal in a Dog

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 56(6), 325–330.

By: M. Risselada*, J. Tuohy*, M. Law*, M. James* & B. Lascelles *

MeSH headings : Amputation, Surgical / veterinary; Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / therapeutic use; Bone Neoplasms / therapy; Bone Neoplasms / veterinary; Carboplatin / administration & dosage; Carboplatin / therapeutic use; Dog Diseases / drug therapy; Dogs; Forelimb / pathology; Forelimb / surgery; Male; Neoplasm Recurrence, Local / surgery; Neoplasm Recurrence, Local / veterinary; Osteosarcoma / therapy; Osteosarcoma / veterinary; Poloxamer / chemistry
TL;DR: This is the first report in the veterinary literature of using poloxamer 407 as a carrier for local delivery of chemotherapeutic drugs in a clinical patient. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 22, 2021

2016 journal article

Association of Canine Osteosarcoma and Monocyte Phenotype and Chemotactic Function

Journal of Veterinary Internal Medicine, 30(4), 1167–1178.

By: J. Tuohy n, B. Lascelles  n, E. Griffith n  & J. Fogle n

author keywords: Bone tumor; Chemoreceptors; Chemotaxis; Immunoregulation
MeSH headings : Animals; Bone Neoplasms / blood; Bone Neoplasms / veterinary; Case-Control Studies; Chemotaxis; Cytokines / metabolism; Disease-Free Survival; Dog Diseases / blood; Dogs; Female; Flow Cytometry / veterinary; Gene Expression Regulation; Male; Monocytes / metabolism; Monocytes / physiology; Osteosarcoma / blood; Osteosarcoma / veterinary; RNA, Messenger / analysis
TL;DR: Dogs with OSA have decreased monocyte chemokine receptor expression and monocytes chemotaxis, potential mechanisms by which OSA might evade the immune response, and reversal of monocyte dysfunction using immunotherapy could improve survival in dogs with Osa. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Durations of Bone Consolidation and External Fixation After Distraction Osteogenesis in Dogs

VETERINARY SURGERY, 43(8), 903–911.

By: J. Tuohy n, D. Marcellin-Little n & E. Griffith n 

MeSH headings : Animals; Cohort Studies; Dogs; External Fixators / veterinary; Female; Fracture Fixation / instrumentation; Fracture Fixation / veterinary; Male; Osteogenesis, Distraction / methods; Osteogenesis, Distraction / veterinary; Osteotomy / instrumentation; Osteotomy / veterinary; Postoperative Complications; Radiography; Radius / diagnostic imaging; Radius / surgery; Recovery of Function; Retrospective Studies; Tibia / diagnostic imaging; Tibia / surgery; Treatment Outcome
TL;DR: Wearing frames with low or moderate stiffness, the absence of mechanical complications, a larger distraction distance, and a larger bone size accelerated bone consolidation, and Optimizing these factors should accelerate bone consolidation and reduce the duration of external fixation. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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