Justin Michael Bradshaw

Works (3)

Updated: July 5th, 2023 15:50

2022 article

Efficacy of an alcohol-based surface disinfectant formulation against human norovirus

Escudero-Abarca, B. I., Goulter, R. M., Bradshaw, J., Faircloth, J., Leslie, R. A., Manuel, C. S., … Jaykus, L.-A. (2022, February 9). Journal of Applied Microbiology.

By: B. Escudero-Abarca n, R. Goulter n, J. Bradshaw n, J. Faircloth n, R. Leslie *, C. Manuel*, J. Arbogast *, L. Jaykus n

author keywords: food safety; food virology; human intestinal enteroids; human norovirus; surface disinfection; surface sanitizing; Tulane virus
MeSH headings : Disinfectants / pharmacology; Disinfection / methods; Ethanol; Humans; Norovirus / genetics; Sodium Hypochlorite / pharmacology; Soil; Stainless Steel
topics (OpenAlex): Viral gastroenteritis research and epidemiology; Viral Infections and Immunology Research; Infection Control and Ventilation
TL;DR: To evaluate the anti‐noroviral efficacy of PURELL® surface sanitizer and disinfectant spray (PSS, an alcohol‐based formulation) using human norovirus GII.4 Sydney and its cultivable surrogate, Tulane virus (TuV, infectivity assay), compared to sodium hypochlorite (NaOCl) solutions. (via Semantic Scholar)
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Source: Web Of Science
Added: March 14, 2022

2010 article

The Center of Accessibility: Dβ Control of V(D)J Recombination

Sikes, M. L., McMillan, R. E., & Bradshaw, J. M. (2010, October 1). Archivum Immunologiae Et Therapiae Experimentalis, Vol. 58, pp. 427–433.

By: M. Sikes n , R. McMillan n & J. Bradshaw n

author keywords: T cell receptor; Tcrb; Transcription; V(D)J recombination; Thymocytes; Double negative
MeSH headings : Acetylation; Animals; Chromatin Assembly and Disassembly; Epigenesis, Genetic; Gene Rearrangement, T-Lymphocyte; Genes, T-Cell Receptor beta; Histones / metabolism; Humans; Protein Processing, Post-Translational; Thymus Gland / enzymology; Thymus Gland / immunology; Transcription, Genetic; VDJ Recombinases / metabolism
topics (OpenAlex): T-cell and B-cell Immunology; Immune Cell Function and Interaction; Immunotherapy and Immune Responses
TL;DR: Examining Tcrb assembly in developing thymocytes, the central roles of RSS elements and germline promoters as foci for epigenetic reorganization of recombinationally accessible gene segments are reviewed in light of recent findings and persistent questions. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 article

A streamlined method for rapid and sensitive chromatin immunoprecipitation

Sikes, M. L., Bradshaw, J. M., Ivory, W. T., Lunsford, J. L., McMillan, R. E., & Morrison, C. R. (2009, March 27). Journal of Immunological Methods, Vol. 344, pp. 58–63.

By: M. Sikes n , J. Bradshaw n, W. Ivory n, J. Lunsford n, R. McMillan n & C. Morrison n

author keywords: Chromatin immunoprecipitation; Histone; Epigenetics; cad; TEA; Thymocyte; Rag
MeSH headings : Animals; Aspartate Carbamoyltransferase / genetics; Aspartate Carbamoyltransferase / metabolism; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) / genetics; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing) / metabolism; Cell Line; Chromatin / genetics; Chromatin / isolation & purification; Chromatin / metabolism; Chromatin Immunoprecipitation / methods; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Dihydroorotase / genetics; Dihydroorotase / metabolism; Gene Knockdown Techniques; Histones / genetics; Histones / metabolism; Mice; Mice, Knockout; RNA Polymerase II / genetics; RNA Polymerase II / metabolism; T-Lymphocytes / metabolism
topics (OpenAlex): Genomics and Chromatin Dynamics; Epigenetics and DNA Methylation; RNA Interference and Gene Delivery
TL;DR: A streamlined ChIP is reported to efficiently carry samples from chromatin to qPCR-compatible DNA in as little as 4 h and it is shown that the protocol readily quantified histone modifications in chromatin from 10(4) Rag-deficient DN thymocytes. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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