Joseph M DeSimone

Impact of Frictional Interactions on Conductivity, Diffusion, and Transference Number in Ether- and Perfluoroether-Based Electrolytes

JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 167(12).

Lithium Salt Distribution and Thermodynamics in Electrolytes Based on Short Perfluoropolyether-block-Poly(ethylene oxide) Copolymers

MACROMOLECULES, 53(4), 1142–1153.

Pulmonary Delivery of Nanoparticle-Bound Toll-like Receptor 9 Agonist for the Treatment of Metastatic Lung Cancer

ACS NANO, 14(6), 7200–7215.

3D Printed Absorber for Capturing Chemotherapy Drugs before They Spread through the Body

ACS CENTRAL SCIENCE, 5(3), 419–427.

Difference between approximate and rigorously measured transference numbers in fluorinated electrolytes

PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 21(15), 7857–7866.

Role of Linker Length and Antigen Density in Nanoparticle Peptide Vaccine

ACS OMEGA, 4(3), 5547–5555.

Controlling release from 3D printed medical devices using CLIP and drug-loaded liquid resins

JOURNAL OF CONTROLLED RELEASE, 278, 9–23.

Formulation of High-Performance Dry Powder Aerosols for Pulmonary Protein Delivery

PHARMACEUTICAL RESEARCH, 35(10).

Impact of formulation on the iontophoretic delivery of the FOLFIRINOX regimen for the treatment of pancreatic cancer

CANCER CHEMOTHERAPY AND PHARMACOLOGY, 81(6), 991–998.

Optimization of Surface Display of DENV2 E Protein on a Nanoparticle to Induce Virus Specific Neutralizing Antibody Responses

BIOCONJUGATE CHEMISTRY, 29(5), 1544–1552.

Spatially controlled coating of continuous liquid interface production microneedles for transdermal protein delivery

JOURNAL OF CONTROLLED RELEASE, 284, 122–132.

Use of iontophoresis for the treatment of cancer

[Review of ]. JOURNAL OF CONTROLLED RELEASE, 284, 144–151.

Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy

NATURE NANOTECHNOLOGY, 12(9), 877-+.

Crosslinked perfluoropolyether solid electrolytes for lithium ion transport

SOLID STATE IONICS, 310, 71–80.

Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer

NANO LETTERS, 17(1), 242–248.

Effect of Anion Size on Conductivity and Transference Number of Perfluoroether Electrolytes with Lithium Salts

JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 164(14), A3511–A3517.

Incipient microphase separation in short chain perfluoropolyether-block-poly(ethylene oxide) copolymers

SOFT MATTER, 13(22), 4047–4056.

Mechanism of ion transport in perfluoropolyether electrolytes with a lithium salt

SOFT MATTER, 13(32), 5389–5396.

Mediating Passive Tumor Accumulation through Particle Size, Tumor Type, and Location

NANO LETTERS, 17(5), 2879–2886.

Co-opting Moore's law: Therapeutics, vaccines and interfacially active particles manufactured via PRINT®

Journal of Controlled Release, 240, 541–543.

Compliant glass-polymer hybrid single ion-conducting electrolytes for lithium batteries

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(1), 52–57.

Conductivity of carbonate- and perfluoropolyether-based electrolytes in porous separators

JOURNAL OF POWER SOURCES, 323, 158–165.

Efficacy and pharmacokinetics of a modified acid-labile docetaxel-PRINT® nanoparticle formulation against non-small-cell lung cancer brain metastases

Nanomedicine, 11(15), 1947–1955.

Iontophoretic device delivery for the localized treatment of pancreatic ductal adenocarcinoma

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(8), 2200–2205.

Layerless fabrication with continuous liquid interface production

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(42), 11703–11708.

Liquid perfluoropolyether electrolytes with enhanced ionic conductivity for lithium battery applications

POLYMER, 100, 126–133.

Nanoparticle surface charge impacts distribution, uptake and lymph node trafficking by pulmonary antigen-presenting cells

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 12(3), 677–687.

Novel materials

Proceedings of the National Academy of Sciences, 113(42), 11667–11669.

Organic Polymer Chemistry in the Context of Novel Processes

ACS CENTRAL SCIENCE, 2(9), 588–597.

Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody Responses

PLOS NEGLECTED TROPICAL DISEASES, 10(10).

Pulmonary Delivery of Butyrylcholinesterase as a Model Protein to the Lung

MOLECULAR PHARMACEUTICS, 13(5), 1626–1635.

Reduction Sensitive PEG Hydrogels for Codelivery of Antigen and Adjuvant To Induce Potent CTLs

Molecular Pharmaceutics, 13(10), 3381–3394.

Relationship between Conductivity, Ion Diffusion, and Transference Number in Perfluoropolyether Electrolytes

MACROMOLECULES, 49(9), 3508–3515.

Single-Step Fabrication of Computationally Designed Microneedles by Continuous Liquid Interface Production

PLOS ONE, 11(9).

Subtumoral analysis of PRINT nanoparticle distribution reveals targeting variation based on cellular and particle properties

Nanomedicine: Nanotechnology, Biology and Medicine, 12(4), 1053–1062.

Tumor Presence Induces Global Immune Changes and Enhances Nanoparticle Clearance

ACS NANO, 10(1), 861–870.

Analysis of human innate immune responses to PRINT fabricated nanoparticles with cross validation using a humanized mouse model

Nanomedicine: Nanotechnology, Biology and Medicine, 11(3), 589–599.

Biodistribution and Toxicity Studies of PRINT Hydrogel Nanoparticles in Mosquito Larvae and Cells

PLOS NEGLECTED TROPICAL DISEASES, 9(5).

Biodistribution and Trafficking of Hydrogel Nanoparticles in Adult Mosquitoes

PLOS NEGLECTED TROPICAL DISEASES, 9(5).

Calibration-Quality Cancer Nanotherapeutics

In Cancer Treatment and Research (pp. 275–291).

Continuous liquid interface production of 3D objects

SCIENCE, 347(6228), 1349–1352.

Controlled analysis of nanoparticle charge on mucosal and systemic antibody responses following pulmonary immunization

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(2), 488–493.

Distribution and Cellular Uptake of PEGylated Polymeric Particles in the Lung Towards Cell-Specific Targeted Delivery

Pharmaceutical Research, 32(10), 3248–3260.

Evaluation of drug loading, pharmacokinetic behavior, and toxicity of a cisplatin-containing hydrogel nanoparticle

JOURNAL OF CONTROLLED RELEASE, 204, 70–77.

Local iontophoretic administration of cytotoxic therapies to solid tumors

SCIENCE TRANSLATIONAL MEDICINE, 7(273).

Nanoparticulate immunotherapy for cancer

JOURNAL OF CONTROLLED RELEASE, 219, 167–180.

Phase Behavior and Electrochemical Characterization of Blends of Perfluoropolyether, Poly(ethylene glycol), and a Lithium Salt

CHEMISTRY OF MATERIALS, 27(2), 597–603.

Preparation and biological evaluation of synthetic and polymer-encapsulated congeners of the antitumor agent pactamycin: Insight into functional group effects and biological activity

BIOORGANIC & MEDICINAL CHEMISTRY, 23(8), 1849–1857.

Rapid and Persistent Delivery of Antigen by Lymph Node Targeting PRINT Nanoparticle Vaccine Carrier To Promote Humoral Immunity

MOLECULAR PHARMACEUTICS, 12(5), 1356–1365.

Reductively Responsive Hydrogel Nanoparticles with Uniform Size, Shape, and Tunable Composition for Systemic siRNA Delivery in Vivo

MOLECULAR PHARMACEUTICS, 12(10), 3518–3526.

Targeted PRINT Hydrogels: The Role of Nanoparticle Size and Ligand Density on Cell Association, Biodistribution, and Tumor Accumulation

NANO LETTERS, 15(10), 6371–6378.

Towards programming immune tolerance through geometric manipulation of phosphatidylserine

BIOMATERIALS, 72, 1–10.

A versatile acid-labile linker for antibody-drug conjugates

MEDCHEMCOMM, 5(9), 1355–1358.

Design of Asymmetric Particles Containing a Charged Interior and a Neutral Surface Charge: Comparative Study on in Vivo Circulation of Polyelectrolyte Microgels

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(28), 9947–9952.

Driving Convergence with Human Diversity

DeSimone, J. M., & Farrell, C. L. (2014, May 28). SCIENCE TRANSLATIONAL MEDICINE, Vol. 6.

Metronomic docetaxel in PRINT® nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer

Molecular Cancer Therapeutics, 13(7), 1750–1757.

Nonflammable perfluoropolyether-based electrolytes for lithium batteries

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(9), 3327–3331.

Particle Replication in Nonwetting Templates Nanoparticles with Tumor Selective Alkyl Silyl Ether Docetaxel Prodrug Reduces Toxicity

Nano Letters, 14(3), 1472–1476.

Analysis of the Murine Immune Response to Pulmonary Delivery of Precisely Fabricated Nano- and Microscale Particles

PLOS ONE, 8(4).

Development of a nanoparticle-based influenza vaccine using the PRINT® technology

Nanomedicine: Nanotechnology, Biology and Medicine, 9(4), 523–531.

Future of the Particle Replication in Nonwetting Templates (PRINT) Technology

[Review of ]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 52(26), 6580–6589.

Generating Better Medicines for Cancer

ACS MACRO LETTERS, 2(5), 393–397.

Nanoparticle clearance is governed by Th1/Th2 immunity and strain background

JOURNAL OF CLINICAL INVESTIGATION, 123(7), 3061–3073.

Nanoparticle drug loading as a design parameter to improve docetaxel pharmacokinetics and efficacy

BIOMATERIALS, 34(33), 8424–8429.

Nanotechnology: An Enduring Bridge Between Engineering and Medicine

The Bridge: Linking Engineering and Society, 7–15.

PRINT Technology: A Versatile Platform for Novel Applications in Nanomedicine

In S. Yin & A. Wei (Eds.), Nanomaterials for Pharmaceutical Scientists. New York: Wiley.

Plasma, tumor and tissue pharmacokinetics of Docetaxel delivered via nanoparticles of different sizes and shapes in mice bearing SKOV-3 human ovarian carcinoma xenograft

Nanomedicine: Nanotechnology, Biology and Medicine, 9(5), 686–693.

RNA Replicon Delivery via Lipid-Complexed PRINT Protein Particles

MOLECULAR PHARMACEUTICS, 10(9), 3366–3374.

Rapidly-Dissolvable Microneedle Patches Via a Highly Scalable and Reproducible Soft Lithography Approach

ADVANCED MATERIALS, 25(36), 5060–5066.

Scalable Manufacture of Built-to-Order Nanomedicine: Spray-Assisted Layer-by-Layer Functionalization of PRINT Nanoparticles

ADVANCED MATERIALS, 25(34), 4707–4713.

Synthesis and characterization of monodisperse uniformly shaped respirable aerosols

AICHE JOURNAL, 59(9), 3184–3194.

Chevreul Medal for Uwe T. Bornscheuer

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Vol. 51, pp. 6563–6563.

Delivery of Multiple siRNAs Using Lipid-Coated PLGA Nanoparticles for Treatment of Prostate Cancer

NANO LETTERS, 12(1), 287–292.

Effect of Aspect Ratio and Deformability on Nanoparticle Extravasation through Nanopores

LANGMUIR, 28(23), 8773–8781.

Engineering nanomedicines using stimuli-responsive biomaterials

[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 64(11), 1021–1030.

In vitro and in vivo assessment of targeting lipid-based nanoparticles to the epidermal growth factor-receptor (EGFR) using a novel Heptameric ZEGFR domain

Journal of Controlled Release, 158(1), 63–71.

Incorporation and Controlled Release of Silyl Ether Prodrugs from PRINT Nanoparticles

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134(18), 7978–7982.

Interview: From traditional polymer science to nanomedicine: the interplay between disciplines to drive innovation

Nanomedicine, 7(8), 1125–1128.

Low Modulus Biomimetic Microgel Particles with High Loading of Hemoglobin

BIOMACROMOLECULES, 13(9), 2748–2759.

PEGylated PRINT Nanoparticles: The Impact of PEG Density on Protein Binding, Macrophage Association, Biodistribution, and Pharmacokinetics

NANO LETTERS, 12(10), 5304–5310.

Reductively Responsive siRNA-Conjugated Hydrogel Nanoparticles for Gene Silencing

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134(17), 7423–7430.

Rendering Protein-Based Particles Transiently Insoluble for Therapeutic Applications

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134(21), 8774–8777.

The effect of particle size on the biodistribution of low-modulus hydrogel PRINT particles

Journal of Controlled Release, 162(1), 37–44.

Tuning Multiphase Amphiphilic Rods to Direct Self-Assembly

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 134(13), 5801–5806.

Amphiphilic Co-networks with Moisture-Induced Surface Segregation for High-Performance Nonfouling Coatings

LANGMUIR, 27(17), 10365–10369.

Biomimetic microlens array with antireflective “moth-eye” surface

Soft Matter, 7(14), 6404.

Dodging Drug-Resistant Cancer with Diamonds

SCIENCE TRANSLATIONAL MEDICINE, 3(73).

Generation of a Library of Particles Having Controlled Sizes and Shapes via the Mechanical Elongation of Master Templates

LANGMUIR, 27(2), 524–528.

Influence of the Fluid-to-Film Transition on Photophysical Properties of MLCT Excited States in a Polymerizable Dimethacrylate Fluid

The Journal of Physical Chemistry B, 115(1), 64–70.

Institutional Profile: The Carolina Center of Cancer Nanotechnology Excellence: past accomplishments and future perspectives

Nanomedicine, 6(1), 19–24.

Investigation of the role of hydrophilic chain length in amphiphilic perfluoropolyether/poly(ethylene glycol) networks: towards high-performance antifouling coatings

Biofouling, 27(10), 1139–1150.

More Effective Nanomedicines through Particle Design

[Review of ]. SMALL, 7(14), 1919–1931.

Novel Platforms for Vascular Carriers with Controlled Geometry

[Review of ]. IUBMB LIFE, 63(8), 596–606.

PRINT: A Novel Platform Toward Shape and Size Specific Nanoparticle Theranostics

Accounts of Chemical Research, 44(10), 990–998.

Photocurable Amphiphilic Perfluoropolyether/Poly(ethylene glycol) Networks for Fouling-Release Coatings

MACROMOLECULES, 44(4), 878–885.

Potent Engineered PLGA Nanoparticles by Virtue of Exceptionally High Chemotherapeutic Loadings

NANO LETTERS, 11(2), 808–813.

Relieving PEGylation

Nature Chemistry, 4(1), 13–14.

Shear thickening and jamming in densely packed suspensions of different particle shapes

Physical Review E, 84(3).

Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 108(2), 586–591.

Challenging nature's monopoly on the creation of well-defined nanoparticles

[Review of ]. NANOMEDICINE, 5(4), 633–639.

Continuous precipitation polymerization of vinylidene fluoride in supercritical carbon dioxide: A model for understanding the molecular-weight distribution

CHEMICAL ENGINEERING SCIENCE, 65(2), 651–659.

Direct Patterning of CdSe Quantum Dots into Sub-100 nm Structures

LANGMUIR, 26(5), 3012–3015.

Generality of shear thickening in dense suspensions

Nature Materials, 9(3), 220–224.

Hierarchical Control of Polymer Composite Nano- and Micro-Structure with Lithography

CHEMISTRY OF MATERIALS, 22(13), 4069–4075.

High Modulus, Low Surface Energy, Photochemically Cured Materials from Liquid Precursors

MACROMOLECULES, 43(24), 10397–10405.

High-Resolution PFPE-based Molding Techniques for Nanofabrication of High-Pattern Density, Sub-20 nm Features: A Fundamental Materials Approach

NANO LETTERS, 10(4), 1421–1428.

Micromolding for the Fabrication of Biological Microarrays

In Methods in Molecular Biology (pp. 249–260).

Multifunctional Shape and Size Specific Magneto-Polymer Composite Particles

NANO LETTERS, 10(4), 1113–1119.

Nano-and micro-cellular foamed thin-walled material, and processes and apparatuses for making the same

Scalable, Shape-Specific, Top-Down Fabrication Methods for the Synthesis of Engineered Colloidal Particles

LANGMUIR, 26(16), 13086–13096.

Shear thickening in densely packed suspensions of spheres and rods confined to few layers

Journal of Rheology, 54(5), 1023–1046.

Strategies in the design of nanoparticles for therapeutic applications

[Review of ]. NATURE REVIEWS DRUG DISCOVERY, 9(8), 615–627.

The Complex Role of Multivalency in Nanoparticles Targeting the Transferrin Receptor for Cancer Therapies

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(32), 11306–11313.

Tunable Bifunctional Silyl Ether Cross-Linkers for the Design of Acid-Sensitive Biomaterials

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(50), 17928–17932.

Ultrathin Cross-Linked Perfluoropolyether Film Coatings from Liquid CO2 and Subsequent UV Curing

CHEMISTRY OF MATERIALS, 22(8), 2411–2413.

Deposition of Copper Particles and Films by the Displacement of Two Immiscible Supercritical Phases and Subsequent Reaction

Chemistry of Materials, 21(5), 913–924.

Fabrication of multiphasic and regio-specifically functionalized PRINT (R) particles of controlled size and shape

NEW JOURNAL OF PHYSICS, 11.

Fluoropolymer synthesis in supercritical carbon dioxide

[Review of ]. JOURNAL OF SUPERCRITICAL FLUIDS, 47(3), 447–457.

Green Chemistry and Engineering with Gas Expanded Liquids and Near-Critical Media

In K. W. Hutchenson, A. M. Scurto, & B. Subramaniam (Eds.), ACS Symposium Series (Vol. 90, pp. 259–273).

Kinetics of the Homopolymerization of Vinylidene Fluoride and Its Copolymerization with Hexafluoropropylene in Supercritical Carbon Dioxide: The Locus of Polymerization

Macromolecules, 42(1), 148–155.

Photochemically Cross-Linked Perfluoropolyether-Based Elastomers: Synthesis, Physical Characterization, and Biofouling Evaluation

MACROMOLECULES, 42(18), 6999–7007.

Photonic Crystal Geometry for Organic Solar Cells

Nano Letters, 9(7), 2742–2746.

Top-down particle fabrication: control of size and shape for diagnostic imaging and drug delivery

[Review of ]. WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 1(4), 391–404.