Works (87)

2021 journal article

Microfluidic devices fitted with "flowver" paper pumps generate steady, tunable gradients for extended observation of chemotactic cell migration

BIOMICROFLUIDICS, 7.

By: S. Baldwin, S. Van Bruggen, J. Koelbl, R. Appalabhotla, J. Bear & J. Haugh

Sources: Web Of Science, ORCID
Added: July 26, 2021

2020 journal article

Mechanistic models of PLC/PKC signaling implicate phosphatidic acid as a key amplifier of chemotactic gradient sensing

PLOS COMPUTATIONAL BIOLOGY, 16(4).

By: J. Nosbisch, A. Rahman, K. Mohan, T. Elston, J. Bear & J. Haugh

Sources: Web Of Science, ORCID
Added: May 26, 2020

2020 journal article

Optical control of MAP kinase kinase 6 (MKK6) reveals that it has divergent roles in pro-apoptotic and anti-proliferative signaling

JOURNAL OF BIOLOGICAL CHEMISTRY, 295(25), 8494–8504.

By: S. Rahman, W. Zhou, A. Deiters & J. Haugh

Sources: Web Of Science, ORCID
Added: July 27, 2020

2019 journal article

Design and evaluation of engineered protein biosensors for live-cell imaging of EGFR phosphorylation

SCIENCE SIGNALING, 12(584).

By: K. Tiruthani, A. Mischler, S. Ahmed, J. Mahinthakumar, J. Haugh & B. Rao

Sources: Web Of Science, ORCID
Added: June 24, 2019

2019 journal article

Emergent spatiotemporal dynamics of the actomyosin network in the presence of chemical gradients

INTEGRATIVE BIOLOGY, 11(6), 280–292.

By: C. Miller, P. LaFosse, S. Asokan, J. Haugh, J. Bear & T. Elston

Sources: Web Of Science, ORCID
Added: October 28, 2019

2019 journal article

Simulating Emergent Spatiotemporal Actomyosin Dynamics to Understand Spatial Regulation of Non-Muscle Myosin II

Biophysical Journal, 116(3), 251a.

By: C. Miller, P. LaFosse, S. Asokan, J. Haugh, J. Bear & T. Elston

Sources: Crossref, ORCID
Added: February 24, 2020

2018 journal article

A Computational Investigation of Asymmetric Emergent Structures in Actomyosin Dynamics During Chemotaxis

Biophysical Journal, 114(3), 381a.

By: C. Miller, S. Asokan, J. Haugh, J. Bear & T. Elston

Sources: Crossref, ORCID
Added: February 24, 2020

2017 journal article

A reaction-diffusion model explains amplification of the PLC/PKC pathway in fibroblast chemotaxis

Biophysical Journal, 113(1), 185–194.

By: K. Mohan, J. Nosbisch, T. Elston, J. Bear & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

Kinetic Modeling and Analysis of the Akt/Mechanistic Target of Rapamycin Complex 1 (mTORC1) Signaling Axis Reveals Cooperative, Feedforward Regulation

Journal of Biological Chemistry, 1(7), jbc.M116.761205.

By: A. Rahman & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Are Filopodia Privileged Signaling Structures in Migrating Cells?

Biophysical Journal, 111(9), 1827–1830.

By: H. Johnson & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Lamellipodia are crucial for haptotactic sensing and response

Journal of Cell Science, 129(12), 2329–2342.

By: S. King, S. Asokan, E. Haynes, S. Zimmerman, J. Rotty, J. Alb, A. Tagliatela, D. Blake ...

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Quantitative analysis of B-lymphocyte migration directed by CXCL13

Integr. Biol., 8(8), 894–903.

By: X. Liu, S. Asokan, J. Bear & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 article

Systems Cell Biology: An Overview

Encyclopedia of Cell Biology, pp. 1–3.

By: D. Lauffenburger, J. Haugh, H. Byrne & R. Linding

Source: ORCID
Added: July 13, 2021

2015 journal article

Development of a tandem affinity phosphoproteomic method with motif selectivity and its application in analysis of signal transduction networks

Journal of Chromatography B, 988, 166–174.

By: L. Herring, K. Grant, K. Blackburn, J. Haugh & M. Goshe

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2015 journal article

F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling

The Journal of Cell Biology, 208(4), 443–455.

By: H. Johnson, S. King, S. Asokan, J. Rotty, J. Bear & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2015 journal article

GMFβ controls branched actin content and lamellipodial retraction in fibroblasts

The Journal of Cell Biology, 209(6), 803–812.

By: E. Haynes, S. Asokan, S. King, H. Johnson, J. Haugh & J. Bear

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2015 journal article

Linking morphodynamics and directional persistence of T lymphocyte migration

Journal of the Royal Society Interface, 12(106).

By: X. Liu, E. Welf & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2015 journal article

Profilin-1 Serves as a Gatekeeper for Actin Assembly by Arp2/3-Dependent and -Independent Pathways

Developmental Cell, 32(1), 54–67.

By: J. Rotty, C. Wu, E. Haynes, C. Suarez, J. Winkelman, H. Johnson, J. Haugh, D. Kovar, J. Bear

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Bi-ligand surfaces with oriented and patterned protein for real-time tracking of cell migration

Colloids and Surfaces B: Biointerfaces, 123, 225–235.

By: V. Vernekar, C. Wallace, M. Wu, J. Chao, S. O’Connor, A. Raleigh, X. Liu, J. Haugh, W. Reichert

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Data-driven modeling reconciles kinetics of ERK phosphorylation, localization, and activity states

Molecular Systems Biology, 10(1), 718–718.

By: S. Ahmed, K. Grant, L. Edwards, A. Rahman, M. Cirit, M. Goshe, J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Deactivation of a Negative Regulator: A Distinct Signal Transduction Mechanism, Pronounced in Akt Signaling

Biophysical Journal, 107(10), L29–L32.

By: A. Rahman & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Directed migration of mesenchymal cells: where signaling and the cytoskeleton meet

Current Opinion in Cell Biology, 30, 74–82.

By: J. Bear & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Mesenchymal Chemotaxis Requires Selective Inactivation of Myosin II at the Leading Edge via a Noncanonical PLCγ/PKCα Pathway

Developmental Cell, 31(6), 747–760.

By: S. Asokan, H. Johnson, A. Rahman, S. King, J. Rotty, I. Lebedeva, J. Haugh, J. Bear

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

PI3K-dependent cross-talk interactions converge with Ras as quantifiable inputs integrated by Erk

Molecular Systems Biology, 7(1), 524–524.

By: C. Wang, M. Cirit & J. Haugh

Sources: ORCID, NC State University Libraries
Added: August 6, 2018

2013 journal article

Bidirectional coupling between integrin-mediated signaling and actomyosin mechanics explains matrix-dependent intermittency of leading-edge motility

Molecular Biology of the Cell, 24(24), 3945–3955.

By: E. Welf, H. Johnson & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2013 journal article

Fibroblast Migration Is Regulated by Myristoylated Alanine-Rich C-Kinase Substrate (MARCKS) Protein

PLoS ONE, 8(6), e66512.

By: L. Ott, E. Sung, A. Melvin, M. Sheats, J. Haugh, K. Adler, S. Jones

Ed(s): P. Aspenstrom

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2013 article

Quantitative Analysis of Phosphoinositide 3-Kinase (PI3K) Signaling Using Live-Cell Total Internal Reflection Fluorescence (TIRF) Microscopy

Current Protocols in Cell Biology.

By: H. Johnson & J. Haugh

Source: ORCID
Added: July 13, 2021

2012 journal article

Cell regulation: A time to signal, a time to respond (Comment on DOI 10.1002/bies.201100172)

BioEssays, 34(7), 528–529.

By: J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2012 journal article

Data-driven modelling of receptor tyrosine kinase signalling networks quantifies receptor-specific potencies of PI3K- and Ras-dependent ERK activation

Biochemical Journal, 441(1), 77–85.

By: M. Cirit & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2012 journal article

Erratum to: Stochastic Dynamics of Membrane Protrusion Mediated by the DOCK180/Rac Pathway in Migrating Cells

Cellular and Molecular Bioengineering, 5(4), 514–516.

By: E. Welf & J. Haugh

Sources: Crossref, ORCID
Added: February 24, 2020

2012 journal article

Live-Cell Fluorescence Microscopy with Molecular Biosensors: What Are We Really Measuring?

Biophysical Journal, 102(9), 2003–2011.

By: J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2012 journal article

Migrating fibroblasts reorient directionality by a metastable, PI3K-dependent mechanism

The Journal of Cell Biology, 197(1), 105–114.

By: E. Welf, S. Ahmed, H. Johnson, A. Melvin & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2012 article

Stochastic Models of Cell Protrusion Arising From Spatiotemporal Signaling and Adhesion Dynamics

Computational Methods in Cell Biology, pp. 223–241.

By: E. Welf & J. Haugh

Source: ORCID
Added: July 13, 2021

2012 article

Stochastic dynamics of membrane protrusion mediated by the DOCK180/Rac pathway in migrating cells (vol 3, pg 30, 2010)

Cellular and Molecular Bioengineering, Vol. 5, pp. 514–516.

By: E. Welf & J. Haugh

Source: NC State University Libraries
Added: August 6, 2018

2012 conference paper

Stochastic models of cell protrusion arising from spatiotemporal signaling and adhesion dynamics

Methods in cell biology, vol 110: computational methods in cell biology, 110, 223–241.

By: E. Welf & J. Haugh

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Systemic Perturbation of the ERK Signaling Pathway by the Proteasome Inhibitor, MG132

PLoS ONE, 7(11), e50975.

By: M. Cirit, K. Grant & J. Haugh

Ed(s): L. Buday

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2011 journal article

Cells see the light to bring signaling under control

Nature Methods, 8(10), 808–809.

By: J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2011 journal article

Guidelines for visualizing and annotating rule-based models

Molecular BioSystems, 7(10), 2779.

By: L. Chylek, B. Hu, M. Blinov, T. Emonet, J. Faeder, B. Goldstein, R. Gutenkunst, J. Haugh ...

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2011 journal article

In Chemotaxing Fibroblasts, Both High-Fidelity and Weakly Biased Cell Movements Track the Localization of PI3K Signaling

Biophysical Journal, 100(8), 1893–1901.

By: A. Melvin, E. Welf, Y. Wang, D. Irvine & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2011 journal article

Poly(vinylmethylsiloxane) Elastomer Networks as Functional Materials for Cell Adhesion and Migration Studies

Biomacromolecules, 12(4), 1265–1271.

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2011 journal article

Quantitative models of signal transduction networks

Communicative & Integrative Biology, 4(3), 353–356.

By: M. Cirit & J. Haugh

Source: ORCID
Added: July 13, 2021

2010 journal article

Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase

Journal of Biological Chemistry, 286(5), 3323–3331.

By: G. Buhrman, V. Kumar, M. Cirit, J. Haugh & C. Mattos

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2010 journal article

Directional Persistence of Cell Migration Coincides with Stability of Asymmetric Intracellular Signaling

Biophysical Journal, 98(1), 67–75.

By: M. Weiger, S. Ahmed, E. Welf & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2010 journal article

Signaling pathways that control cell migration: models and analysis

Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 3(2), 231–240.

By: E. Welf & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2010 journal article

Stochastic Dynamics of Membrane Protrusion Mediated by the DOCK180/Rac Pathway in Migrating Cells

Cellular and Molecular Bioengineering, 3(1), 30–39.

By: E. Welf & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2010 journal article

Stochastic Model of Integrin-Mediated Signaling and Adhesion Dynamics at the Leading Edges of Migrating Cells

PLoS Computational Biology, 6(2), e1000688.

By: M. Cirit, M. Krajcovic, C. Choi, E. Welf, A. Horwitz & J. Haugh

Ed(s): A. Asthagiri

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2010 journal article

Systematic Quantification of Negative Feedback Mechanisms in the Extracellular Signal-regulated Kinase (ERK) Signaling Network

Journal of Biological Chemistry, 285(47), 36736–36744.

By: M. Cirit, C. Wang & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2009 journal article

A Bipolar Clamp Mechanism for Activation of Jak-Family Protein Tyrosine Kinases

PLoS Computational Biology, 5(4), e1000364.

By: D. Barua, J. Faeder & J. Haugh

Ed(s): N. Kannan

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2009 journal article

Analysis of Reaction-Diffusion Systems with Anomalous Subdiffusion

Biophysical Journal, 97(2), 435–442.

By: J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2009 journal article

PI3K‐dependent cross‐talk interactions converge with Ras as quantifiable inputs integrated by Erk

Molecular Systems Biology, 5(1), 246.

By: C. Wang, M. Cirit & J. Haugh

Sources: Crossref, ORCID
Added: August 28, 2020

2009 journal article

Spontaneous phosphoinositide 3-kinase signaling dynamics drive spreading and random migration of fibroblasts

Journal of Cell Science, 122(3), 313–323.

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2008 journal article

Biophysics: Cells get in shape for a crawl

Nature, 453(7194), 461–462.

By: J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2008 journal article

Cell population-based model of dermal wound invasion with heterogeneous intracellular signaling properties

Cell Adhesion & Migration, 2(2), 137–145.

By: M. Monine & J. Haugh

Source: ORCID
Added: July 13, 2021

2008 journal article

Combinatorial Signal Transduction Responses Mediated by Interleukin-2 and -4 Receptors in a Helper TH2 Cell Line

Cellular and Molecular Bioengineering, 1(2-3), 163–172.

By: K. Comfort & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2008 journal article

Computational Models of Tandem Src Homology 2 Domain Interactions and Application to Phosphoinositide 3-Kinase

Journal of Biological Chemistry, 283(12), 7338–7345.

By: D. Barua, J. Faeder & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2008 journal article

First International Conference on Biomolecular Engineering (ICBE)

Biotechnology Progress, 24(1), 1–1.

By: M. DeLisa & J. Haugh

Source: NC State University Libraries
Added: August 6, 2018

2008 article

Mathematical Modelling of Biological Signaling Networks

Haugh, J. M. (2008, May). Wiley Encyclopedia of Chemical Biology.

By: J. Haugh

Source: ORCID
Added: July 13, 2021

2008 journal article

Signal Transduction at Point-Blank Range: Analysis of a Spatial Coupling Mechanism for Pathway Crosstalk

Biophysical Journal, 95(5), 2172–2182.

By: M. Monine & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2007 journal article

Membrane-Binding/Modification Model of Signaling Protein Activation and Analysis of Its Control by Cell Morphology

Biophysical Journal, 92(11), L93–L95.

By: J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2007 journal article

Structure-Based Kinetic Models of Modular Signaling Protein Function: Focus on Shp2

Biophysical Journal, 92(7), 2290–2300.

By: D. Barua, J. Faeder & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2006 journal article

Deterministic Model of Dermal Wound Invasion Incorporating Receptor-Mediated Signal Transduction and Spatial Gradient Sensing

Biophysical Journal, 90(7), 2297–2308.

By: J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2006 journal article

Effectiveness factor for spatial gradient sensing in living cells

Chemical Engineering Science, 61(17), 5603–5611.

By: J. Haugh & I. Schneider

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2006 journal article

Fast imaging of partially conductive linear cracks using impedance data

Inverse Problems, 22(4), 1337–1358.

By: K. Bryan, J. Haugh & D. McCune

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2006 journal article

Mechanisms of Gradient Sensing and Chemotaxis: Conserved Pathways, Diverse Regulation

Cell Cycle, 5(11), 1130–1134.

By: I. Schneider & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2006 journal article

Quantitative model of Ras–phosphoinositide 3-kinase signalling cross-talk based on co-operative molecular assembly

Biochemical Journal, 393(1), 235–243.

By: H. Kaur, C. Park, J. Lewis & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2005 journal article

Quantitative elucidation of a distinct spatial gradient-sensing mechanism in fibroblasts

The Journal of Cell Biology, 171(5), 883–892.

By: I. Schneider & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2005 journal article

Reactions on cell membranes: Comparison of continuum theory and Brownian dynamics simulations

The Journal of Chemical Physics, 123(7), 074908.

By: M. Monine & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2005 journal article

Spatial Analysis of 3′ Phosphoinositide Signaling in Living Fibroblasts, III: Influence of Cell Morphology and Morphological Polarity

Biophysical Journal, 89(2), 1420–1430.

By: I. Schneider, E. Parrish & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2004 journal article

Mathematical Model of Human Growth Hormone (hGH)-Stimulated Cell Proliferation Explains the Efficacy of hGH Variants as Receptor Agonists or Antagonists

Biotechnology Progress, 20(5), 1337–1344.

By: J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2004 journal article

On the cross-regulation of protein tyrosine phosphatases and receptor tyrosine kinases in intracellular signaling

Journal of Theoretical Biology, 230(1), 119–132.

By: J. Haugh, I. Schneider & J. Lewis

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2004 journal article

Spatial Analysis of 3′ Phosphoinositide Signaling in Living Fibroblasts: I. Uniform Stimulation Model and Bounds on Dimensionless Groups

Biophysical Journal, 86(1), 589–598.

By: J. Haugh & I. Schneider

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2004 journal article

Spatial Analysis of 3′ Phosphoinositide Signaling in Living Fibroblasts: II. Parameter Estimates for Individual Cells from Experiments

Biophysical Journal, 86(1), 599–608.

By: I. Schneider & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2003 journal article

Kinetic Analysis of Platelet-derived Growth Factor Receptor/Phosphoinositide 3-Kinase/Akt Signaling in Fibroblasts

Journal of Biological Chemistry, 278(39), 37064–37072.

By: C. Park, I. Schneider & J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2002 journal article

A Unified Model for Signal Transduction Reactions in Cellular Membranes

Biophysical Journal, 82(2), 591–604.

By: J. Haugh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2002 journal article

Active EGF receptors have limited access to PtdIns(4,5)P2 in endosomes: implications for phospholipase C and PI 3-kinase signaling

Journal of Cell Science.

Source: ORCID
Added: July 13, 2021

2002 journal article

Active EGF receptors have limited access to Ptdlns(4,5)P-2 in endosomes: implications for phospholipase C and PI 3-kinase signaling

Journal of Cell Science, 115(2), 303–310.

By: J. Haugh & T. Meyer

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Localization of Receptor-Mediated Signal Transduction Pathways: The Inside Story

Molecular Interventions, 2(5), 292–307.

By: J. Haugh

Source: ORCID
Added: July 13, 2021

2000 journal article

Mathematical modeling of epidermal growth factor receptor signaling through the phospholipase C pathway: Mechanistic insights and predictions for molecular interventions

Biotechnology and Bioengineering, 70(2), 225–238.

By: J. Haugh, A. Wells & D. Lauffenburger

Source: ORCID
Added: July 13, 2021

2000 journal article

Mathematical modeling of epidermal growth factor receptor signaling through the phospholipase C pathway: mechanistic insights and predictions for molecular interventions

Biotechnology and Bioengineering, 70(2), 225–238.

By: J. Haugh, A. Wells & D. Lauffenburger

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2000 journal article

Spatial Sensing in Fibroblasts Mediated by 3′ Phosphoinositides

The Journal of Cell Biology, 151(6), 1269–1280.

By: J. Haugh, F. Codazzi, M. Teruel & T. Meyer

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1999 journal article

Effect of Epidermal Growth Factor Receptor Internalization on Regulation of the Phospholipase C- 1 Signaling Pathway

Journal of Biological Chemistry, 274(13), 8958–8965.

By: J. Haugh, K. Schooler, A. Wells, H. Wiley & D. Lauffenburger

Source: ORCID
Added: July 13, 2021

1999 journal article

Internalized Epidermal Growth Factor Receptors Participate in the Activation of p21ras in Fibroblasts

Journal of Biological Chemistry, 274(48), 34350–34360.

By: J. Haugh, A. Huang, H. Wiley, A. Wells & D. Lauffenburger

Source: ORCID
Added: July 13, 2021

1998 journal article

Analysis of Receptor Internalization as a Mechanism for Modulating Signal Transduction

Journal of Theoretical Biology, 195(2), 187–218.

By: J. Haugh & D. Lauffenburger

Source: ORCID
Added: July 13, 2021

1998 journal article

Scratching the (cell) surface: cytokine engineering for improved ligand/receptor trafficking dynamics

Chemistry & Biology, 5(10), R257–R263.

By: D. Lauffenburger, E. Fallon & J. Haugh

Source: ORCID
Added: July 13, 2021

1997 journal article

Physical modulation of intracellular signaling processes by locational regulation

Biophysical Journal, 72(5), 2014–2031.

By: J. Haugh & D. Lauffenburger

Source: ORCID
Added: July 13, 2021

article

Modeling Intracellular Signal Transduction Processes

Haugh, J. M., & Weiger, M. C. Chemical Biology, pp. 1061–1081.

By: J. Haugh & M. Weiger

Source: ORCID
Added: July 13, 2021

dataset

PI3K's Pivotal Role in Cell Migration

Welf, E., Ahmed, S., Johnson, H. E., Melvin, A. T., & Haugh, J. M. SciVee.

By: E. Welf, S. Ahmed, H. Johnson, A. Melvin & J. Haugh

Source: ORCID
Added: July 13, 2021

Employment

2000 - present

North Carolina State University Raleigh, NC, US
Professor Chemical & Biomolecular Engineering

Education

1995 - 1999

Massachusetts Institute of Technology Cambridge, MA, US
PhD Chemical Engineering

1990 - 1994

North Carolina State University Raleigh, NC, US
BS Chemical Engineering