Jenna Nicole Meanor

Graduate School

Works (1)

Updated: June 17th, 2023 21:49

2022 journal article

Modified Histone Peptides Linked to Magnetic Beads Reduce Binding Specificity

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(3).

By: J. Meanor n, A. Keung n  & B. Rao n 

Contributors: J. Meanor n, A. Keung n  & B. Rao n 

author keywords: yeast surface display; histone post-translational modifications; affinity reagents; protein engineering; chromodomain; binder; reader; antibody; epigenome engineering; synthetic biology
MeSH headings : HEK293 Cells; Histone Code; Histones / metabolism; Humans; Jurkat Cells; K562 Cells; Protein Array Analysis; Protein Binding; Protein Engineering; Protein Processing, Post-Translational; Saccharomyces cerevisiae
TL;DR: Specific experimental conditions that affect binding specificities of post-translationally modified histones in classic protein engineering platforms are described and likely explain the relative difficulty with histone targets in these platforms. (via Semantic Scholar)
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Added: February 21, 2022

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