Jessie Rene Chappel

College of Sciences

Works (3)

Updated: April 5th, 2024 17:51

2024 journal article

Guided optimization of ToxPi model weights using a Semi-Automated approach

COMPUTATIONAL TOXICOLOGY, 29.

By: J. Fleming n, J. House*, J. Chappel n, A. Motsinger-Reif* & D. Reif*

author keywords: Machine learning; Feature weighting; Exposure assessment; Chemical toxicity; Ordinal regression; Genetic algorithm
Sources: Web Of Science, NC State University Libraries
Added: January 16, 2024

2023 article

Aggregated Molecular Phenotype Scores: Enhancing Assessment and Visualization of Mass Spectrometry Imaging Data for Tissue-Based Diagnostics

Chappel, J. R., King, M. E., Fleming, J., Eberlin, L. S., Reif, D. M., & Baker, E. S. (2023, August 14). ANALYTICAL CHEMISTRY, Vol. 8.

By: J. Chappel n, M. King*, J. Fleming n, L. Eberlin*, D. Reif* & E. Baker*

TL;DR: Initial comparisons of cancerous human tissues to their normal or benign counterparts illustrated that AMP scores distinguished phenotypes with high accuracy, sensitivity, and specificity, leading to high diagnostic accuracy and interpretability. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 28, 2023

2023 article

From big data to big insights: statistical and bioinformatic approaches for exploring the lipidome

Chappel, J. R., Kirkwood-Donelson, K. I., Reif, D. M., & Baker, E. S. (2023, October 25). ANALYTICAL AND BIOANALYTICAL CHEMISTRY, Vol. 10.

By: J. Chappel n, K. Kirkwood-Donelson*, D. Reif* & E. Baker*

author keywords: Lipidomics; Univariate; Multivariate; Pathway; Enrichment
TL;DR: A framework for guiding lipidomic data analysis to promote a greater assessment of lipidomic results, while understanding potential advantages and weaknesses along the way is provided. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 20, 2023

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