@article{suyemoto_hamrick_spears_horton_washington_havell_borst_orndorff_2013, title={Extrauterine Listeriosis in the gravid mouse influences embryonic growth and development}, volume={8}, number={8}, journal={PLoS One}, author={Suyemoto, M. M. and Hamrick, T. S. and Spears, P. A. and Horton, J. R. and Washington, I. M. and Havell, E. A. and Borst, L. B. and Orndorff, P. E.}, year={2013} }
 @article{temple_miyamoto_mehta_capitini_von stetina_barnes_christensen_horton_spears_orndorff_2010, title={Identification and Characterization of Two Bordetella avium Gene Products Required for Hemagglutination}, volume={78}, ISSN={["1098-5522"]}, DOI={10.1128/iai.00140-10}, abstractNote={ABSTRACT}, number={6}, journal={INFECTION AND IMMUNITY}, author={Temple, Louise M. and Miyamoto, David M. and Mehta, Manju and Capitini, Christian M. and Von Stetina, Stephen and Barnes, H. John and Christensen, Vern L. and Horton, John R. and Spears, Patricia A. and Orndorff, Paul E.}, year={2010}, month={Jun}, pages={2370–2376} }
 @article{spears_suyemoto_palermo_horton_hamrick_havell_orndorff_2008, title={A Listeria monocytogenes mutant defective in bacteriophage attachment is attenuated in orally inoculated mice and impaired in enterocyte intracellular growth}, volume={76}, ISSN={["0019-9567"]}, DOI={10.1128/IAI.00283-08}, abstractNote={ABSTRACT}, number={9}, journal={INFECTION AND IMMUNITY}, author={Spears, Patricia A. and Suyemoto, M. Mitsu and Palermo, Angela M. and Horton, John R. and Hamrick, Terri S. and Havell, Edward A. and Orndorff, Paul E.}, year={2008}, month={Sep}, pages={4046–4054} }
 @article{hanson_calkins_horton_2006, title={The effect of preharvest calcium loading on tenderness of beef longissimus, supraspinatus and semitendinosus muscle}, volume={17}, ISSN={["1046-0756"]}, DOI={10.1111/j.1745-4573.2006.00038.x}, abstractNote={ABSTRACT}, number={2}, journal={JOURNAL OF MUSCLE FOODS}, author={Hanson, DJ and Calkins, CR and Horton, J}, year={2006}, month={Apr}, pages={155–164} }
 @article{spears_engle_platter_lloyd_belk_horton_2003, title={Effects of high dietary calcium propionate and dietary cation-anion balance on calcium metabolism and longissimus muscle tenderness in finishing steers}, volume={19}, ISBN={1080-7446}, DOI={10.15232/s1080-7446(15)31461-3}, abstractNote={Abstract Forty-eight Angus and Angus-cross steers (initial BW = 657 ± 5.7 kg) were used in a 2 × 2 factorial design to determine whether feeding an anionic diet or high dietary concentrations of a soluble calcium (Ca propionate) source or both would alter Ca metabolism and subsequently longissimus tenderness. Treatments consisted of 1) control, 2) 4% Ca propionate (CaProp), 3) 2% NH 4 Cl (anionic diet), and 4) CaProp plus 2% NH 4 Cl. Experimental diets were fed for 7 d prior to slaughter. Steers were individually fed using electronic Calan gate feeders. Blood samples were obtained on d 3 and 7 at 2 h post feeding for plasma Ca determination. A striploin steak was obtained from each carcass at 48 h post harvest for muscle Ca analysis and Warner-Bratzler shear force (WBSF) determination. Addition of CaProp or NH 4 Cl to the high concentrate finishing diet reduced (P 4 Cl and CaProp, indicating that their effects were additive. Carcass characteristics were not affected by CaProp, but the anionic diet tended to reduce hot carcass weights (P=0.13) and longissimus areas (P=0.09). Plasma Ca concentrations were slightly greater in steers fed CaProp on d 3 (P}, number={6}, journal={Professional Animal Scientists}, author={Spears, J. W. and Engle, T. E. and Platter, W. R. and Lloyd, K. E. and Belk, K. E. and Horton, J.}, year={2003}, pages={424} }
 @article{hamrick_diaz_havell_horton_orndorff_2003, title={Influence of extracellular bactericidal agents on bacteria within macrophages}, volume={71}, ISSN={["0019-9567"]}, DOI={10.1128/IAI.71.2.1016-1019.2003}, abstractNote={ABSTRACT}, number={2}, journal={INFECTION AND IMMUNITY}, author={Hamrick, TS and Diaz, AH and Havell, EA and Horton, JR and Orndorff, PE}, year={2003}, month={Feb}, pages={1016–1019} }
 @article{hamrick_horton_spears_havell_smoak_orndorff_2003, title={Influence of pregnancy on the pathogenesis of listeriosis in mice inoculated intragastrically}, volume={71}, ISSN={["1098-5522"]}, DOI={10.1128/IAI.71.9.5202-5209.2003}, abstractNote={ABSTRACT}, number={9}, journal={INFECTION AND IMMUNITY}, author={Hamrick, TS and Horton, JR and Spears, PA and Havell, EA and Smoak, IW and Orndorff, PE}, year={2003}, month={Sep}, pages={5202–5209} }
 @article{valenski_harris_spears_horton_orndorff_2003, title={The product of the fimI gene is necessary for Escherichia coli type 1 pilus biosynthesis}, volume={185}, ISSN={["0021-9193"]}, DOI={10.1128/JB.185.16.5007-5011.2003}, abstractNote={ABSTRACT}, number={16}, journal={JOURNAL OF BACTERIOLOGY}, author={Valenski, ML and Harris, SL and Spears, PA and Horton, JR and Orndorff, PE}, year={2003}, month={Aug}, pages={5007–5011} }
 @article{harris_spears_havell_hamrick_horton_orndorff_2001, title={Characterization of Escherichia coli type 1 pilus mutants with altered binding specificities}, volume={183}, ISSN={["0021-9193"]}, DOI={10.1128/JB.183.13.4099-4102.2001}, abstractNote={ABSTRACT}, number={13}, journal={JOURNAL OF BACTERIOLOGY}, author={Harris, SL and Spears, PA and Havell, EA and Hamrick, TS and Horton, JR and Orndorff, PE}, year={2001}, month={Jul}, pages={4099–4102} }
 @article{lu_hill_hood_greeson_horton_orndorff_herndon_tonelli_2001, title={Formation of antibiotic, biodegradable polymers by processing with Irgasan DP300R (Triclosan) and its inclusion compound with beta-cyclodextrin}, volume={82}, DOI={10.1002/app.1852.abs}, abstractNote={The inclusion compound (IC) between the FDA-approved antibacterial Irgasan DP300 (Trichlosan), and β-cyclodextrin (CD) has been formed. When the Irgasan–β-CD–IC is embedded in biodegradeable/bioabsorbable films of poly(ϵ-caprolactone) (PCL) at low levels (a few wt %), they are rendered resistant to the growth of E. coli bacteria. When these same PCL films embedded with Irgasan–β-CD–IC are used as the adhesive for laminating cotton fabrics, we observe the resulting cotton laminates to also be resistant to the growth of E. coli bacteria. These results hold promise for the fabrication of bacteria-resistant polymer films and fibers, as well as antibacterial fabrics, by means of simple melt processing with Irgasan–β-CD–IC. © 2001 John Wiley & Sons, Inc. J Appl Polym Sci 82: 300–309, 2001}, number={2}, journal={Journal of Applied Polymer Science}, author={Lu, J. and Hill, M. A. and Hood, M. and Greeson, D. F. and Horton, J. R. and Orndorff, P. E. and Herndon, A. S. and Tonelli, A. E.}, year={2001}, pages={300–309} }
 @article{williams_dunnick_horton_greenwell_eldridge_elwell_sills_2001, title={p-nitrobenzoic acid alpha(2u) nephropathy in 13-week studies is not associated with renal carcinogenesis in 2-year feed studies}, volume={29}, DOI={10.1080/019262301317226302}, abstractNote={ The objective of this study was to characterize the renal toxicity and carcinogenicity of p-nitrobenzoi c acid in F344 rats. Dose levels in 13-week and 2-year studies ranged from 630—10,000 ppm and 1,250—5,000 ppm, respectively. At 13 weeks, renal lesions included minimal to mild hyaline droplet accumulation in male rats and karyomegaly in male and female rats. At 2 years, renal lesions included proximal tubule epithelial cell hyperplasia in male rats and oncocytic hyperplasia in high-dose male and female rats, and a decreased severity of nephropathy in males and females. The hyaline droplets in renal tubular epithelial cells of male rats at 13 weeks were morphologically similar to those described in α2u-globulin nephropathy. Using immunohistochemica l methods, α2u-globulin accumulation was associated with the hyaline droplets. In addition, at 13 weeks, cell proliferation as detected by PCNA immunohistochemistry was signifi cantly increased in males exposed to 5,000 and 10,000 ppm when compared to controls. Cytotoxicity associated with α2u-globulin nephropathy such as single-cell necrosis of the P2 segment epithelium or accumulation of granular casts in the outer medulla did not occur in the 13-week study. In addition, chronic treatment related nephrotoxic lesions attributed to accumulation of α 2u-globulin such as linear foci of mineralization within the renal papilla, hyperplasia of the renal pelvis urothelium and kidney tumors were not observed. Although there was histologic evidence of α2u-globulin accumulation in male rats at 13 weeks, the minimal severity of nephropathy suggests that the degree of cytotoxicity was below the threshold, which would contribute to the development of renal tumors at 2 years. }, number={5}, journal={Toxicologic Pathology}, author={Williams, K. D. and Dunnick, J. and Horton, J. and Greenwell, A. and Eldridge, S. R. and Elwell, M. and Sills, R. C.}, year={2001}, pages={507–513} }
 @article{metcalf_almond_routh_horton_dillman_orndorff_2000, title={Experimental Salmonella typhi infection in the domestic pig, Sus scrofa domestica}, volume={29}, ISSN={["0882-4010"]}, DOI={10.1006/mpat.2000.0367}, abstractNote={The domestic pig, Sus scrofa domestica, was examined as a model for typhoid fever, a severe and systemic disease of humans caused by Salmonella typhi. Six pigs were inoculated 1 week post-weaning with approximately 10(10)colony forming units (cfu) of wild type Salmonella typhi strain ISP1820 intranasally and observed for 3 weeks. S. typhi was cultured from the tonsils of 50% of the pigs at necropsy. Cultures from all other organs analysed (ileum, colon, spleen and liver) were negative. No clinical or histopathological signs of disease were observed. Pigs inoculated in parallel with swine-virulent S. choleraesuis all exhibited signs of systemic salmonellosis indicating that the parameters of the experimental infection with S. typhi (e.g. route) were appropriate. Whereas the pig has a gastrointestinal tract that is very similar to humans, our results indicated that the unique features of host and microbe interaction needed to produce typhoid fever were not mimicked in swine. Nevertheless, our observation of tonsillar involvement was consistent with former observations of S. choleraesuis and S. typhimurium infections in swine and supports a role for the tonsil in all porcine salmonella infections.}, number={2}, journal={MICROBIAL PATHOGENESIS}, author={Metcalf, ES and Almond, GW and Routh, PA and Horton, JR and Dillman, RC and Orndorff, PE}, year={2000}, month={Aug}, pages={121–126} }
 @article{hamrick_harris_spears_havell_horton_russell_orndorff_2000, title={Genetic characterization of Escherichia coli type 1 pilus adhesin mutants and identification of a novel binding phenotype}, volume={182}, ISSN={["0021-9193"]}, DOI={10.1128/JB.182.14.4012-4021.2000}, abstractNote={ABSTRACT}, number={14}, journal={JOURNAL OF BACTERIOLOGY}, author={Hamrick, TS and Harris, SL and Spears, PA and Havell, EA and Horton, JR and Russell, PW and Orndorff, PE}, year={2000}, month={Jul}, pages={4012–4021} }
 @article{hamrick_havell_horton_orndorff_2000, title={Host and bacterial factors involved in the innate ability of mouse macrophages to eliminate internalized unopsonized Escherichia coli}, volume={68}, ISSN={["0019-9567"]}, DOI={10.1128/IAI.68.1.125-132.2000}, abstractNote={ABSTRACT}, number={1}, journal={INFECTION AND IMMUNITY}, author={Hamrick, TS and Havell, EA and Horton, JR and Orndorff, PE}, year={2000}, month={Jan}, pages={125–132} }
 @article{huang_taylor_gerber_orndorff_horton_tonelli_1999, title={Formation of antibiotic, biodegradable/bioabsorbable polymers by processing with neomycin sulfate and its inclusion compound with beta-cyclodextrin}, volume={74}, ISSN={["0021-8995"]}, DOI={10.1002/(SICI)1097-4628(19991024)74:4<937::AID-APP20>3.0.CO;2-K}, abstractNote={Samples of pure neomycin sulfate and its inclusion compound (IC) with β-cyclodextrin were implanted into films of poly(L-lactic acid) (PLLA) and poly(e-caprolactone) (PCL). Both polymers have been widely used commercially to make sutures. The antibacterial activity of these films against Escherichia coli was tested. Films made by either solution casting or melt pressing were divided into the following three groups: (1) plain polymer films, (2) those embedded with pure neomycin sulfate, and (3) those embedded with neomycin sulfate-β-cyclodextrin IC. Filter paper treated with 1.5 μL of 10 mg/μL Kanamycin and neomycin were used as controls and resulted in 11- and 8-mm zones of inhibition/or antibacterial activity, respectively. Small discs (ca. 2% of total area) cut from solution-cast films of PLLA and PCL containing 50 wt % neomycin sulfate IC had 17- and 16-mm zones of inhibition, and PLLA and PCL containing 50 wt % pure neomycin sulfate deterred bacterial growth, resulting in 19-mm zones of inhibition. Melt-pressed films containing 10 wt % pure neomycin sulfate or its IC, showed 17- and 11-mm zones of inhibition for PLLA films, respectively, while PCL films showed 13- and 9-mm zones of inhibition, respectively. For melt-pressed films that contain 0.01 wt % pure neomycin sulfate or its IC, PLLA films showed 11- and 9.5-mm zones of inhibition, respectively, while PCL films showed 11- and 10-mm zones of inhibition, respectively. Since an antibiotic, bioabsorbable suture does not require surgical removal, implanting an inclusion compound in the suture might allow the slow release of antibiotic, thereby guarding against postsurgical infection and also protecting the antibiotic from degradation during the melt-spinning process used to make the suture. © 1999 John Wiley & Sons, Inc. J Appl Polym Sci 74: 937–947, 1999}, number={4}, journal={JOURNAL OF APPLIED POLYMER SCIENCE}, author={Huang, L and Taylor, H and Gerber, M and Orndorff, PE and Horton, JR and Tonelli, A}, year={1999}, month={Oct}, pages={937–947} }