Works (5)

Updated: April 5th, 2024 06:51

2023 journal article

Global gene expression analysis of the turkey hen hypothalamo-pituitary-gonadal axis during the preovulatory hormonal surge


By: K. Brady*, H. Liu n, J. Hicks n, J. Long* & T. Porter*

author keywords: hypothalamo-pituitary-gonadal axis; preovulatory surge; turkey; RNA sequencing; pathway analysis
MeSH headings : Female; Animals; Progesterone / metabolism; Chickens / metabolism; Ovarian Follicle / physiology; Luteinizing Hormone / metabolism; Ovulation; Gene Expression Profiling / veterinary; Granulosa Cells / metabolism
TL;DR: Gene Ontology (GO) analysis revealed key roles for metabolic processes, steroid hormone feedback, and hypoxia induced gene expression changes in the hypothalamus, pituitary, F1G, and F5G respectively, and upstream analysis identified potential regulators of downstream gene expression. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (Web of Science)
Source: Web Of Science
Added: April 11, 2023

2021 journal article

TGF-beta 2 Reduces the Cell-Mediated Immunogenicity of Equine MHC-Mismatched Bone Marrow-Derived Mesenchymal Stem Cells Without Altering Immunomodulatory Properties


By: A. Berglund n, J. Long n, J. Robertson n & L. Schnabel n

author keywords: mesenchymal stem cell; TGF-β 2; cytotoxicity; immunogenicity; major histocompatibility complex; allogeneic
TL;DR: It is indicated that treating MSCs with TGF-β2 is a promising strategy to reduce the cell-mediated immunogenicity of MHC-mismatched M SCs and facilitate allogeneic MSC therapy. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 8, 2021

2019 journal article

Ultra-long-acting tunable biodegradable and removable controlled release implants for drug delivery


By: S. Benhabbour n, M. Kovarova*, C. Jones*, D. Copeland*, R. Shrivastava n, M. Swanson*, C. Sykes*, P. Ho* ...

MeSH headings : Anti-Retroviral Agents / pharmacokinetics; Biodegradable Plastics / chemistry; Chemistry, Pharmaceutical; Delayed-Action Preparations / chemistry; Delayed-Action Preparations / pharmacology; Drug Delivery Systems / methods; Drug Liberation; HIV Infections / drug therapy; Humans; Kinetics; Materials Testing; Polymers / metabolism; Pyrrolidinones; Rheology; Solubility
TL;DR: An ultra-long-acting tunable, biodegradable, and removable polymer-based delivery system that offers sustained drug delivery for up to one year for HIV treatment or prophylaxis and optimize and demonstrate the release of 6 different drugs over a period of up to a year. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: October 7, 2019

2018 journal article

Pooled Platelet-Rich Plasma Lysate Therapy Increases Synoviocyte Proliferation and Hyaluronic Acid Production While Protecting Chondrocytes From Synoviocyte-Derived Inflammatory Mediators


By: J. Gilbertie n, J. Long n, A. Schubert n, A. Berglund n, T. Schaer* & L. Schnabel n

author keywords: platelet-rich plasma lysate; osteoarthritis; IL-1 beta; LPS; HA; collagen type II; aggrecan; MMP-13
TL;DR: The results of this study support continued investigation into the use of pooled PRP-L for the treatment of osteoarthritis and warrant further in-vitro studies to discern the mechanisms of action of PRp-L. (via Semantic Scholar)
Source: Web Of Science
Added: December 17, 2018

2012 journal article

Construction and Immunological Evaluation of Dual Cell Surface Display of HIV-1 Gag and Salmonella enterica Serovar Typhimurium FliC in Lactobacillus acidophilus for Vaccine Delivery


By: A. Kajikawa*, L. Zhang*, J. Long n, S. Nordone n, L. Stoeker n, A. LaVoy*, S. Bumgardner n, T. Klaenhammer n, G. Dean*

MeSH headings : AIDS Vaccines / administration & dosage; AIDS Vaccines / genetics; AIDS Vaccines / immunology; Administration, Oral; Animals; Bacterial Vaccines / administration & dosage; Bacterial Vaccines / genetics; Bacterial Vaccines / immunology; Cell Surface Display Techniques / methods; Cells, Cultured; Dendritic Cells / immunology; Female; Flagellin / genetics; Flagellin / immunology; HIV-1 / genetics; HIV-1 / immunology; Humans; Intestinal Mucosa / immunology; Lactobacillus acidophilus / genetics; Leukocytes, Mononuclear / immunology; Mice; Mice, Inbred BALB C; Salmonella typhimurium / genetics; Salmonella typhimurium / immunology; Vaccines, Synthetic / administration & dosage; Vaccines, Synthetic / genetics; Vaccines, Synthetic / immunology; gag Gene Products, Human Immunodeficiency Virus / genetics; gag Gene Products, Human Immunodeficiency Virus / immunology
TL;DR: Results suggested that the Gag-displaying L. acidophilus elicited specific immune responses and the coexistence of FliC conferred an adjuvant effect on local IgA production. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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