Jennifer Pancorbo

Works (5)

Updated: November 24th, 2025 14:23

2025 article

Comparison of anion-exchange chromatography matrices for purification of linear and supercoiled plasmid in a direct lysate workflow

Stoops, M., Shastry, S., Martinez-Mata, C., Elhanafi, D., & Pancorbo, J. (2025, October 24). Journal of Chromatography A.

By: M. Stoops n, S. Shastry n, C. Martinez-Mata n, D. Elhanafi n & J. Pancorbo n

topics (OpenAlex): Protein purification and stability; Viral Infectious Diseases and Gene Expression in Insects; Monoclonal and Polyclonal Antibodies Research
Source: NC State University Libraries
Added: November 22, 2025

2024 journal article

Serotype-agnostic affinity purification of adeno-associated virus (AAV) via peptide-functionalized chromatographic resins

Journal of Chromatography A, 1734, 465320.

By: S. Shastry n, E. Barbieri n, A. Minzoni n, W. Chu n, S. Johnson n, M. Stoops n, J. Pancorbo n, G. Gilleskie n  ...

Contributors: S. Shastry n, E. Barbieri n, A. Minzoni n, W. Chu n, S. Johnson n, M. Stoops n, J. Pancorbo n, . al.

author keywords: Gene therapy; Adeno-associated virus; Peptide ligands; Affinity chromatography; Transduction activity
MeSH headings : Dependovirus / isolation & purification; Dependovirus / genetics; Dependovirus / chemistry; Chromatography, Affinity / methods; Peptides / chemistry; Peptides / isolation & purification; Serogroup; Humans; Hydrogen-Ion Concentration; Genetic Vectors; HEK293 Cells
topics (OpenAlex): Virus-based gene therapy research; RNA Interference and Gene Delivery; Viral Infectious Diseases and Gene Expression in Insects
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: September 1, 2024

2023 journal article

Peptide ligands for the affinity purification of adeno‐associated viruses from HEK 293 cell lysates

Biotechnology and Bioengineering, 120(8), 2283–2300.

By: W. Chu n, S. Shastry n, E. Barbieri n, R. Prodromou n, P. Greback‐Clarke n, W. Smith n, B. Moore n, R. Kilgore n ...

Contributors: W. Chu n, S. Shastry n, E. Barbieri n, R. Prodromou n, P. Greback-Clarke n, W. Smith n, B. Moore n, . al.

author keywords: adeno-associated virus; affinity chromatography; HEK 293 lysate; peptide ligands; virus purification
MeSH headings : Humans; Dependovirus / genetics; HEK293 Cells; Ligands; Peptides / genetics; Peptides / metabolism; Amino Acid Sequence; Genetic Vectors
topics (OpenAlex): Virus-based gene therapy research; Viral Infectious Diseases and Gene Expression in Insects; RNA Interference and Gene Delivery
TL;DR: Peptide ligands that selectively capture AAVs and release them under mild conditions are introduced, affording high recovery, high recovery of host cell proteins (HCPs), and high transduction activity of the purified viruses. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 7, 2023

2023 journal article

Rational design and experimental evaluation of peptide ligands for the purification of adeno‐associated viruses via affinity chromatography

Biotechnology Journal, 19(1).

By: S. Shastry n, W. Chu n, E. Barbieri n, P. Greback‐Clarke n, W. Smith  n, C. Cummings n, A. Minzoni n, J. Pancorbo n ...

Contributors: S. Shastry n, W. Chu n, E. Barbieri n, P. Greback-Clarke n, W. Smith  n, C. Cummings n, A. Minzoni n, . al.

author keywords: adeno-associated virus; affinity chromatography; gene therapy; peptide ligands; transduction activity
MeSH headings : Humans; Dependovirus / genetics; Capsid / chemistry; HEK293 Cells; Transduction, Genetic; Peptides / metabolism; Ligands; Chromatography, Affinity; Genetic Vectors / genetics
topics (OpenAlex): Virus-based gene therapy research; Viral Infectious Diseases and Gene Expression in Insects; CAR-T cell therapy research
TL;DR: This study introduces a cohort of peptide ligands that mimic the biorecognition activity of the AAV receptor (AAVR) and anti-AAV antibody A20, enable product elution under near-physiological conditions (pH 6.0) and grant extended reusability by withstanding multiple regenerations. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: October 10, 2023

2014 article

Comprehensive hands‐on training for influenza vaccine manufacturing: A WHO–BARDA–BTEC partnership for global workforce development

Ruiz, J., Gilleskie, G. L., Brown, P., Burnett, B., & Carbonell, R. G. (2014, August 18). Biochemistry and Molecular Biology Education, Vol. 42, pp. 414–419.

By: J. Ruiz n, G. Gilleskie n , P. Brown n, B. Burnett* & R. Carbonell n

author keywords: workforce development; developing countries vaccine manufacturers; influenza vaccine; global vaccine capacity-building; active learning; cGMP manufacturing
MeSH headings : Capacity Building / methods; Education, Continuing / methods; Humans; Influenza Vaccines / biosynthesis; Influenza Vaccines / immunology; Internet; Program Development / methods; Reproducibility of Results; Technology, Pharmaceutical / education; Technology, Pharmaceutical / methods; United States; United States Dept. of Health and Human Services; World Health Organization
topics (OpenAlex): Influenza Virus Research Studies; vaccines and immunoinformatics approaches; Vaccine Coverage and Hesitancy
TL;DR: The Biomanufacturing Training and Education Center at North Carolina State University has addressed the need for training for staff supporting operations within vaccine production facilities by developing and delivering a comprehensive training program, consisting of three courses: Fundamentals of cGMP Influenza Vaccine Manufacturing, Advanced Upstream Processes for Influenza vaccine Manufacturing, and Advanced Downstream processeses for influenza vaccine Manufacturing. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2026) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.