Johanna Stephens Dutton

Works (1)

Updated: June 15th, 2023 22:54

2021 article

Hyperglycemia minimally alters primary self-renewing human colonic epithelial cells while TNFα-promotes severe intestinal epithelial dysfunction

Dutton, J. S., Hinman, S. S., Kim, R., Attayek, P. J., Maurer, M., Sims, C. S., & Allbritton, N. L. (2021, May 14). Integrative Biology.

By: J. Dutton n, S. Hinman *, R. Kim *, P. Attayek n, M. Maurer n, C. Sims*, N. Allbritton*

author keywords: hyperglycemia; glucose; TNF alpha; colon; large intestine; intestinal epithelium; primary tissue
MeSH headings : Colon; Epithelial Cells; Humans; Hyperglycemia; Intestinal Mucosa; Tumor Necrosis Factor-alpha
topics (OpenAlex): Pancreatic and Hepatic Oncology Research; Hyperglycemia and glycemic control in critically ill and hospitalized patients; Cancer Cells and Metastasis; Gut microbiota and health; Diet and metabolism studies; Immune cells in cancer
TL;DR: Results suggest that TNFα acted as the dominant modulator of the epithelium relative to glucose, and that control of inflammation rather than glucose may be key to maintaining intestinal homeostasis. (via Semantic Scholar)
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Source: Web Of Science
Added: July 26, 2021

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