Works (30)

2022 journal article

Scattered seeding of CAR T cells in solid tumors augments anticancer efficacy

NATIONAL SCIENCE REVIEW, 9(3).

By: H. Li*, Z. Wang*, E. Archibong, Q. Wu*, G. Chen, Q. Hu, T. Ci*, Z. Chen ...

author keywords: drug delivery; CAR T therapy; microneedle patch; solid tumor treatment; cell delivery
Source: Web Of Science
Added: March 28, 2022

2021 article

Bioorthogonal catalytic patch

Chen, Z., Li, H., Bian, Y., Wang, Z., Chen, G., Zhang, X., … Gu, Z. (2021, May 10). NATURE NANOTECHNOLOGY.

By: Z. Chen, H. Li*, Y. Bian*, Z. Wang*, G. Chen, X. Zhang, Y. Miao*, D. Wen ...

Source: Web Of Science
Added: June 10, 2021

2020 journal article

CRISPR-Cas12a delivery by DNA-mediated bioresponsive editing for cholesterol regulation

SCIENCE ADVANCES, 6(21).

By: W. Sun, J. Wang, Q. Hu, X. Zhou*, A. Khademhosseini* & Z. Gu

Source: Web Of Science
Added: June 22, 2020

2020 journal article

Engineered PD-L1-Expressing Platelets Reverse New-Onset Type 1 Diabetes

ADVANCED MATERIALS, 32(26).

By: X. Zhang, Y. Kang*, J. Wang, J. Yan n, Q. Chen*, H. Cheng, P. Huang*, Z. Gu

author keywords: drug delivery; immune tolerance; platelets; programmed death-ligand 1 (PD-L1); type 1 diabetes (T1D)
Source: Web Of Science
Added: June 8, 2020

2020 journal article

Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs

NATURE BIOMEDICAL ENGINEERING, 4(5), 499–506.

Source: Web Of Science
Added: February 17, 2020

2019 journal article

A Dual-Bioresponsive Drug-Delivery Depot for Combination of Epigenetic Modulation and Immune Checkpoint Blockade

ADVANCED MATERIALS, 31(17).

By: H. Ruan*, Q. Hu, D. Wen, Q. Chen, G. Chen, Y. Lu*, J. Wang, H. Cheng, W. Lu*, Z. Gu

author keywords: bioresponsive materials; drug delivery; epigenetic modulation; immune checkpoint blockade; immunotherapy
Source: Web Of Science
Added: May 13, 2019

2019 journal article

A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth

ACS NANO, 13(4), 4354–4360.

By: G. Yang*, Q. Chen, D. Wen, Z. Chen, J. Wang, G. Chen, Z. Wang*, X. Zhang ...

author keywords: drug delivery; microneedle; exosome; keratin; hair regrowth; transdermal drug delivery
Source: Web Of Science
Added: June 4, 2019

2019 journal article

A forskolin-conjugated insulin analog targeting endogenous glucose-transporter for glucose-responsive insulin delivery

BIOMATERIALS SCIENCE, 7(11), 4508–4513.

Source: Web Of Science
Added: December 16, 2019

2019 journal article

Adipocytes as Anticancer Drug Delivery Depot

MATTER, 1(5), 1203–1214.

By: D. Wen, J. Wang, G. Van Den Driessche, Q. Chen*, Y. Zhang, G. Chen, H. Li*, J. Soto* ...

Source: Web Of Science
Added: April 6, 2020

2019 review

Advances in transdermal insulin delivery

[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 139, 51–70.

author keywords: Drug delivery; Transdermal delivery; Insulin; Diabetes; Iontophoresis; Electroporation; Ultrasound; Jet injection; Microneedle
Source: Web Of Science
Added: September 9, 2019

2019 journal article

Bioresponsive Protein Complex of aPD1 and aCD47 Antibodies for Enhanced Immunotherapy

NANO LETTERS, 19(8), 4879–4889.

By: Q. Chen, G. Chen, J. Chen*, J. Shen*, X. Zhang, J. Wang, A. Chan, Z. Gu

author keywords: Drug delivery; immunotherapy; immune checkpoint blockade; bioresponsive; nanomedicine
Source: Web Of Science
Added: September 3, 2019

2019 journal article

Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs

SCIENCE ADVANCES, 5(7).

By: J. Wang, J. Yu, Y. Zhang, X. Zhang, A. Kahkoska*, G. Chen, Z. Wang*, W. Sun ...

Source: Web Of Science
Added: August 19, 2019

2019 journal article

Glucose transporter inhibitor-conjugated insulin mitigates hypoglycemia

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(22), 10744–10748.

author keywords: drug delivery; diabetes; glucose-responsive; insulin; insulin analog
Source: Web Of Science
Added: June 17, 2019

2019 journal article

In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment

NATURE NANOTECHNOLOGY, 14(1), 89-+.

By: Q. Chen, C. Wang n, X. Zhang, G. Chen, Q. Hu, H. Li*, J. Wang, D. Wen ...

Source: Web Of Science
Added: January 21, 2019

2019 journal article

Shape-controlled synthesis of liquid metal nanodroplets for photothermal therapy

NANO RESEARCH, 12(6), 1313–1320.

By: J. Yan n, X. Zhang, Y. Liu, Y. Ye, J. Yu, Q. Chen, J. Wang, Y. Zhang ...

author keywords: liquid metal; melanin nanoparticles; nanomedicine; shape-controlled synthesis; photothermal therapy
Source: Web Of Science
Added: June 17, 2019

2019 article

Topical and Transdermal Nanomedicines for Cancer Therapy

NANOTHERANOSTICS FOR CANCER APPLICATIONS, Vol. 5, pp. 231–251.

By: Y. Ye, J. Wang, W. Sun, H. Bomba & Z. Gu

Source: Web Of Science
Added: October 26, 2020

2018 journal article

Bioresponsive Microneedles with a Sheath Structure for H2O2 and pH Cascade-Triggered Insulin Delivery

SMALL, 14(14).

author keywords: diabetes; drug delivery; insulin; microneedles; stimuli-responsive
Source: Web Of Science
Added: August 6, 2018

2018 journal article

Cardiac cell-integrated microneedle patch for treating myocardial infarction

SCIENCE ADVANCES, 4(11).

By: J. Tang, J. Wang, K. Huang, Y. Ye, T. Su, L. Qiao n, M. Hensley, T. Caranasos* ...

Source: Web Of Science
Added: December 31, 2018

2018 journal article

Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy

NATURE BIOMEDICAL ENGINEERING, 2(11), 831–840.

By: Q. Hu, W. Sun, J. Wang, H. Ruan*, X. Zhang, Y. Ye, S. Shen*, C. Wang n ...

Source: Web Of Science
Added: November 26, 2018

2018 journal article

Engineering PD-1-Presenting Platelets for Cancer Immunotherapy

NANO LETTERS, 18(9), 5716–5725.

author keywords: Drug delivery; platelet; immune checkpoint blockade; immunotherapy; nanomedicine
Source: Web Of Science
Added: October 16, 2018

2018 journal article

In situ formed reactive oxygen species-responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy

SCIENCE TRANSLATIONAL MEDICINE, 10(429).

By: C. Wang*, J. Wang, X. Zhang, S. Yu*, D. Wen, Q. Hu, Y. Ye, H. Bomba* ...

Source: Web Of Science
Added: August 6, 2018

2018 journal article

PD-1 Blockade Cellular Vesicles for Cancer Immunotherapy

ADVANCED MATERIALS, 30(22).

By: X. Zhang, C. Wang n, J. Wang, Q. Hu, B. Langworthy*, Y. Ye n, W. Sun n, J. Lin* ...

author keywords: cancer immunotherapy; cell therapy; drug delivery; immune checkpoint blockade; nanomedicine
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Enhanced Cisplatin Chemotherapy by Iron Oxide Nanocarrier-Mediated Generation of Highly Toxic Reactive Oxygen Species

NANO LETTERS, 17(2), 928–937.

By: P. Ma*, H. Xiao*, C. Yu*, J. Liu*, Z. Cheng*, H. Song*, X. Zhang*, C. Li* ...

author keywords: Drug delivery; cisplatin; iron oxide; Fenton's reaction; reactive oxygen species
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Insulin-responsive glucagon delivery for prevention of hypoglycemia

Small (Weinheim An Der Bergstrasse, Germany), 13(19).

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Locally Induced Adipose Tissue Browning by Microneedle Patch for Obesity Treatment

ACS NANO, 11(9), 9223–9230.

By: Y. Zhang, Q. Liu*, J. Yu, S. Yu n, J. Wang, L. Qiang*, Z. Gu

author keywords: drug delivery; microneedle patch; obesity; browning agent; adipose tissue
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Red Blood Cells for Glucose-Responsive Insulin Delivery

ADVANCED MATERIALS, 29(18).

Source: Web Of Science
Added: August 6, 2018

2017 journal article

Synthetic beta cells for fusion-mediated dynamic insulin secretion

Nature Chemical Biology, 14(1), 86–93.

Sources: Web Of Science, Crossref
Added: August 6, 2018

2016 journal article

Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus

ADVANCED MATERIALS, 28(43), 9573-+.

By: Q. Hu, C. Qian, W. Sun, J. Wang, Z. Chen, H. Bomba, H. Xin, Q. Shen, Z. Gu

Source: Web Of Science
Added: August 6, 2018

2016 journal article

Synergistic Transcutaneous Immunotherapy Enhances Antitumor Immune Responses through Delivery of Checkpoint Inhibitors

ACS NANO, 10(9), 8956–8963.

By: Y. Ye, J. Wang, Q. Hu*, G. Hochu, H. Xin, C. Wang, Z. Gu

author keywords: drug delivery; immunotherapy; anti-PD1; IDO; microneedle
Source: Web Of Science
Added: August 6, 2018

journal article

Core-Shell Microneedle Gel for Self-Regulated Insulin Delivery

Wang, J. Q., Ye, Y. Q., Yu, J. C., Kahkoska, A. R., Zhang, X. D., Wang, C., … Gu, Z. ACS Nano, 12(3), 2466–2473.

By: J. Wang, Y. Ye, J. Yu, A. Kahkoska, X. Zhang, C. Wang, W. Sun, R. Corder ...

Source: NC State University Libraries
Added: August 6, 2018