Works (67)

Updated: April 3rd, 2024 17:53

2023 journal article

Duration of exposure to epidural anesthesia at delivery, DNA methylation in umbilical cord blood and their association with offspring asthma in Non-Hispanic Black women

ENVIRONMENTAL EPIGENETICS, 9(1).

By: Y. Wang n, J. Tzeng n, Y. Huang n, R. Maguire n, C. Hoyo n & T. Allen*

author keywords: epidural anesthesia; labor analgesia; asthma; health disparities; DNA methylation; mediation analysis
Source: Web Of Science
Added: February 13, 2023

2023 journal article

The prediction of Alzheimer's disease through multi-trait genetic modeling

FRONTIERS IN AGING NEUROSCIENCE, 15.

By: K. Clark*, W. Fu*, C. Liu*, P. Ho*, H. Wang*, W. Lee*, S. Chou*, L. Wang*, J. Tzeng n

author keywords: Alzheimer's disease; statistical genetics; genetic risk; risk scores; polygenic trait
Source: Web Of Science
Added: August 21, 2023

2023 journal article

Transfer learning with false negative control improves polygenic risk prediction

PLOS GENETICS, 19(11).

By: X. Jeng n, Y. Hu n, V. Venkat n, T. Lu* & J. Tzeng n

co-author countries: Taiwan, Province of China 🇹🇼
Source: Web Of Science
Added: March 4, 2024

2022 journal article

Phylogeny-guided microbiome OTU-specific association test (POST)

MICROBIOME, 10(1).

By: C. Huang n, B. Callahan n, M. Wu*, S. Holloway n, H. Brochu n, W. Lu n, X. Peng n, J. Tzeng n

author keywords: Association test; Phylogenetic tree; Kernel machine regression
MeSH headings : Computational Biology / methods; Computer Simulation; Female; Humans; Infant, Newborn; Microbiota / genetics; Phylogeny; Premature Birth
Sources: Web Of Science, ORCID
Added: June 20, 2022

2021 journal article

An Integrative Co-localization (INCO) Analysis for SNV and CNV Genomic Features With an Application to Taiwan Biobank Data

FRONTIERS IN GENETICS, 12.

By: Q. Yu*, T. Lu*, T. Hsiao*, C. Lin*, C. Wu*, J. Tzeng n, C. Hsiao*

co-author countries: Taiwan, Province of China 🇹🇼
author keywords: co-localization; gene-level; integrative analysis; Taiwan Biobank; CNV; SNV; CNV-SNV cross-platform interaction; rare variant
Source: Web Of Science
Added: December 6, 2021

2021 journal article

Gene-set integrative analysis of multi-omics data using tensor-based association test

BIOINFORMATICS, 37(16), 2259–2265.

By: S. Chang*, M. Yang n, W. Lu n, Y. Huang*, Y. Huang n, H. Hung*, J. Miecznikowski*, T. Lu*, J. Tzeng n

co-author countries: Taiwan, Province of China 🇹🇼
Source: Web Of Science
Added: October 18, 2021

2021 journal article

SEAGLE: A Scalable Exact Algorithm for Large-Scale Set-Based Gene-Environment Interaction Tests in Biobank Data

FRONTIERS IN GENETICS, 12.

By: J. Chi*, I. Ipsen n, T. Hsiao*, C. Lin, L. Wang*, W. Lee*, T. Lu*, J. Tzeng n

co-author countries: Taiwan, Province of China 🇹🇼
author keywords: gene-based GxE test for biobank data; GxE collapsing test for biobank data; GxE test for large-scale sequencing data; scalable GEI test; gene-environment variance component test; gene-environment kernel test; regional-based gene-environment test
Sources: Web Of Science, ORCID
Added: November 29, 2021

2020 journal article

Association test using Copy Number Profile Curves (CONCUR) enhances power in rare copy number variant analysis

PLOS COMPUTATIONAL BIOLOGY, 16(5).

By: A. Brucker n, W. Lu n, R. West n, Q. Yu*, C. Hsiao*, T. Hsiao*, C. Lin*, P. Magnusson* ...

co-author countries: Sweden 🇸🇪 Taiwan, Province of China 🇹🇼

Ed(s): J. Ma n

MeSH headings : Algorithms; Area Under Curve; Computational Biology / methods; DNA Copy Number Variations / genetics; Genetic Predisposition to Disease / genetics; Genetic Variation / genetics; Genome, Human / genetics; Genome-Wide Association Study / methods; Genomics / methods; Humans; Polymorphism, Single Nucleotide / genetics; Spatial Analysis
Sources: Web Of Science, ORCID
Added: June 22, 2020

2020 journal article

Effective SNP ranking improves the performance of eQTL mapping

GENETIC EPIDEMIOLOGY, 44(6), 611–619.

By: X. Jeng n, J. Rhyne n, T. Zhang n & J. Tzeng n

co-author countries: Taiwan, Province of China 🇹🇼
author keywords: HC ranking; hotspot; multivariate response; penalized regression; trans-eQTL
MeSH headings : Computer Simulation; Data Analysis; Gene Expression Regulation; Genome-Wide Association Study; Humans; Models, Genetic; Polymorphism, Single Nucleotide / genetics; Quantitative Trait Loci / genetics
Source: Web Of Science
Added: April 14, 2020

2020 journal article

FastLORS: Joint modelling for expression quantitative trait loci mapping in R

STAT, 9(1).

By: J. Rhyne n, X. Jeng n, E. Chi & J. Tzeng n

author keywords: block coordinate descent; eQTL mapping; low-rank approximation; proximal gradient descent; sparse regression
Sources: Web Of Science, ORCID
Added: May 7, 2020

2020 journal article

Robust kernel association testing (RobKAT)

GENETIC EPIDEMIOLOGY, 44(3), 272–282.

co-author countries: Taiwan, Province of China 🇹🇼
author keywords: kernel association test; multimarker hypothesis test; robust regression; schizophrenia; semiparametric
MeSH headings : Algorithms; Computer Simulation; Genetic Association Studies; Humans; Models, Genetic; Polymorphism, Single Nucleotide / genetics; Selection, Genetic
Sources: Web Of Science, ORCID
Added: March 23, 2020

2020 journal article

The association between neuraxial anesthesia and the development of childhood asthma - a secondary analysis of the newborn epigenetics study cohort

CURRENT MEDICAL RESEARCH AND OPINION, 36(6), 1025–1032.

By: Y. Huang n, J. Tzeng n, R. Maguire n, C. Hoyo n & T. Allen*

author keywords: Anesthesia; opioid analgesics; asthma; children; sex-specific
MeSH headings : Adult; Anesthesia, Epidural / adverse effects; Anesthesia, Obstetrical / adverse effects; Asthma / etiology; Cesarean Section / adverse effects; Child; Child, Preschool; Epigenesis, Genetic; Female; Humans; Infant, Newborn; Logistic Models; Male; Pregnancy; Retrospective Studies
Source: Web Of Science
Added: June 22, 2020

2019 personal communication

Genetic loci determining total immunoglobulin E levels from birth through adulthood

Yao, T.-C., Chung, R.-H., Lin, C.-Y., Tsai, P.-C., Chang, W.-C., Yeh, K.-W., … Huang, J.-L. (2019, March).

By: T. Yao*, R. Chung*, C. Lin*, P. Tsai*, W. Chang*, K. Yeh*, M. Tsai*, S. Liao* ...

co-author countries: Taiwan, Province of China 🇹🇼
MeSH headings : Age Factors; Female; Genetic Loci; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Immunoglobulin E / blood; Immunoglobulin E / immunology; Pregnancy
Source: Web Of Science
Added: March 11, 2019

2019 journal article

Identifying individual risk rare variants using protein structure guided local tests (POINT)

PLOS COMPUTATIONAL BIOLOGY, 15(2).

By: R. West n, W. Lu n, D. Rotroff*, M. Kuenemann n, S. Chang*, M. Wu*, M. Wagner*, J. Buse* ...

co-author countries: Taiwan, Province of China 🇹🇼
MeSH headings : Angiopoietin-Like Protein 4 / genetics; Cholesterol Ester Transfer Proteins / genetics; Computational Biology / methods; Computer Simulation; Genetic Association Studies / methods; Genetic Predisposition to Disease / genetics; Genetic Variation / genetics; Humans; Models, Genetic; Proprotein Convertase 9 / genetics; Protein Structure, Tertiary; Risk Factors; Sequence Analysis, DNA / methods
Source: Web Of Science
Added: March 25, 2019

2019 journal article

Reference equations for spirometry in healthy Asian children aged 5 to 18 years in Taiwan

WORLD ALLERGY ORGANIZATION JOURNAL, 12(11).

By: S. Chang*, H. Tsai*, J. Tzeng n, K. Yeh*, L. Chen*, S. Lai*, S. Liao*, M. Hua* ...

co-author countries: Taiwan, Province of China 🇹🇼
author keywords: Asian; Children; Prediction equations; Pulmonary function; Reference values; Spirometry
Source: Web Of Science
Added: January 13, 2020

2019 article

VARIANCE COMPONENT TEST FOR CROSS-DISORDER PATHWAY ANALYSIS

EUROPEAN NEUROPSYCHOPHARMACOLOGY, Vol. 29, pp. 1204–1205.

By: J. Szatkiewicz*, R. Marceau n, Z. Yilmaz*, C. Bulik*, J. Crowley*, M. Mattheisen*, P. Sullivan*, W. Lu n ...

co-author countries: Germany 🇩🇪
Sources: Web Of Science, ORCID
Added: August 12, 2019

2018 journal article

Cadmium exposure increases the risk of juvenile obesity: a human and zebrafish comparative study

International Journal of Obesity, 42(7), 1285–1295.

Contributors: A. Green n, C. Hoyo n, C. Mattingly n, Y. Luo n, J. Tzeng n, S. Murphy*, D. Buchwalter n, A. Planchart n

MeSH headings : Adipogenesis / drug effects; Animals; Cadmium / adverse effects; Cadmium / analysis; Cadmium / blood; Disease Models, Animal; Environmental Exposure / adverse effects; Environmental Exposure / analysis; Female; Humans; Infant, Newborn; Male; Maternal Exposure / adverse effects; Metals, Heavy / adverse effects; Metals, Heavy / analysis; Pediatric Obesity / blood; Pediatric Obesity / chemically induced; Pediatric Obesity / epidemiology; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects / blood; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / epidemiology; Prospective Studies; Socioeconomic Factors; United States / epidemiology; Zebrafish / metabolism
Sources: Crossref, ORCID
Added: August 7, 2019

2018 journal article

Efficient Signal Inclusion With Genomic Applications

Journal of the American Statistical Association, 1–23.

By: X. Jeng n, T. Zhang n & J. Tzeng n

co-author countries: Taiwan, Province of China 🇹🇼
author keywords: Dimension reduction; False-negative control; False-positive control; Ultrahigh dimension; Variable screening
Source: Crossref
Added: February 21, 2020

2018 journal article

Inference on phenotype-specific effects of genes using multivariate kernel machine regression

GENETIC EPIDEMIOLOGY, 42(1), 64–79.

By: A. Maity n, J. Zhao n, P. Sullivan* & J. Tzeng n

co-author countries: Taiwan, Province of China 🇹🇼

Contributors: A. Maity n, J. Zhao n, P. Sullivan* & J. Tzeng n

author keywords: kernel machine; multivariate regression; mixed models; restricted maximum likelihood; variance components
MeSH headings : Age Factors; Antipsychotic Agents / therapeutic use; Computer Simulation; Genetic Markers / genetics; Humans; Likelihood Functions; Models, Genetic; Phenotype; Sex Factors
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

On the substructure controls in rare variant analysis: Principal components or variance components?

GENETIC EPIDEMIOLOGY, 42(3), 276–287.

co-author countries: Taiwan, Province of China 🇹🇼

Contributors: Y. Luo n, A. Maity n, M. Wu*, C. Smith n, Q. Duan*, Y. Li*, J. Tzeng n

author keywords: population substructure; principal components analysis; rare variant association tests; variance components
MeSH headings : Computer Simulation; Confounding Factors, Epidemiologic; Genetic Association Studies; Genetic Variation; Humans; Models, Genetic; Principal Component Analysis
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Reexamining Dis/Similarity-Based Tests for Rare-Variant Association with Case-Control Samples

GENETICS, 209(1), 105–113.

co-author countries: Switzerland 🇨🇭 Taiwan, Province of China 🇹🇼
author keywords: cross-sample comparison; within-sample comparison; U-statistics
MeSH headings : Algorithms; Case-Control Studies; Computer Simulation; Genetic Association Studies / methods; Genetic Variation; Humans; Models, Genetic; Models, Statistical; Phenotype; Sample Size
Source: Web Of Science
Added: August 6, 2018

2018 personal communication

Rejoinder to "A note on testing and estimation in marker-set association study using semiparametric quantile regression kernel machine"

Kong, D., Maity, A., Hsu, F.-C., & Tzeng, J.-Y. (2018, June).

By: D. Kong*, A. Maity n, F. Hsu* & J. Tzeng n

co-author countries: Canada 🇨🇦 Taiwan, Province of China 🇹🇼

Contributors: D. Kong*, A. Maity n, F. Hsu* & J. Tzeng n

MeSH headings : Biomarkers; Models, Genetic; Models, Statistical
Sources: Web Of Science, ORCID
Added: October 16, 2018

2017 journal article

A Powerful Test for SNP Effects on Multivariate Binary Outcomes Using Kernel Machine Regression

Statistics in Biosciences, 10(1), 117–138.

By: C. Davenport*, A. Maity n, P. Sullivan* & J. Tzeng n

co-author countries: Taiwan, Province of China 🇹🇼

Contributors: C. Davenport*, A. Maity n, P. Sullivan* & J. Tzeng n

author keywords: Correlated binary responses; Generalized estimating equations; IBS kernel; Kernel machine; Non-parametric regression
Sources: Crossref, ORCID
Added: September 4, 2019

2017 journal article

A new method for detecting associations with rare copy-number variants

European Neuropsychopharmacology, 27, S165–166.

By: J. Szatkiewicz, J. Tzeng, P. Magnusson & P. Sullivan

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Fast Bayesian variable screenings for binary response regressions with small sample size

JOURNAL OF STATISTICAL COMPUTATION AND SIMULATION, 87(14), 2708–2723.

By: S. Chang*, J. Tzeng n & R. Chen*

co-author countries: Taiwan, Province of China 🇹🇼
author keywords: g-prior; logistic regression; probit regression; sure independence screening
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Maternal blood cadmium, lead and arsenic levels, nutrient combinations, and offspring birthweight

BMC Public Health, 17.

By: Y. Luo, L. McCullough, J. Tzeng, T. Darrah, A. Vengosh, R. Maguire, A. Maity, C. Samuel-Hodge ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Across-Platform Imputation of DNA Methylation Levels Incorporating Nonlocal Information Using Penalized Functional Regression

GENETIC EPIDEMIOLOGY, 40(4), 333–340.

author keywords: DNA methylation; imputation; penalized functional regression; epigenome-wide association study
MeSH headings : CpG Islands / genetics; DNA Methylation; Epigenesis, Genetic; Genetic Association Studies / methods; Humans; Leukemia, Myeloid, Acute / genetics; Linear Models; Models, Genetic
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Detection of Gene-Gene Interactions Using Multistage Sparse and Low-Rank Regression

BIOMETRICS, 72(1), 85–94.

By: H. Hung*, Y. Lin*, P. Chen*, C. Wang*, S. Huang* & J. Tzeng n

co-author countries: Taiwan, Province of China 🇹🇼
author keywords: Asymptotic normality; Gene-gene interactions; Low-rank approximation; Over-parametrization; Screen-and-Clean; Sparsity
MeSH headings : Algorithms; Computer Simulation; Data Interpretation, Statistical; High-Throughput Screening Assays / methods; Models, Statistical; Pattern Recognition, Automated / methods; Protein Interaction Mapping / methods; Regression Analysis; Reproducibility of Results; Sensitivity and Specificity
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Rare variants association analysis in large-scale sequencing studies at the single locus level

PLoS Computational Biology, 12(6).

By: X. Jeng, Z. Daye, W. Lu & J. Tzeng

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Testing and estimation in marker-set association study using semiparametric quantile regression kernel machine

BIOMETRICS, 72(2), 364–371.

By: D. Kong*, A. Maity n, F. Hsu*, J. Tzeng n & Biometrics

co-author countries: Taiwan, Province of China 🇹🇼

Contributors: D. Kong*, A. Maity n, F. Hsu* & J. Tzeng n

author keywords: Bootstrap; Genetic marker-set association; Kernel machines; Permutation; Quantile regression; Semiparametric; Smoothing parameter; Testing
MeSH headings : Algorithms; Biomarkers; Biometry / methods; Clinical Trials as Topic; Computer Simulation; Genetic Association Studies; Homocysteine / blood; Humans; Linear Models; Models, Genetic; Models, Statistical; Polymorphism, Single Nucleotide; Regression Analysis
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

A Fast Multiple-Kernel Method With Applications to Detect Gene-Environment Interaction

GENETIC EPIDEMIOLOGY, 39(6), 456–468.

By: R. Marceau n, W. Lu n, S. Holloway n, M. Sale*, B. Worrall*, S. Williams*, F. Hsu*, J. Tzeng n

co-author countries: Taiwan, Province of China 🇹🇼
author keywords: multiple-kernel analysis; kernel machine regression; exon level association test; gene-environment interaction; gene-gene interactions
MeSH headings : Algorithms; Gene-Environment Interaction; Genetic Variation; Homocysteine / metabolism; Humans; Models, Genetic; Quantitative Trait Loci; Regression Analysis; Risk Factors; Software; Stroke / etiology; Vitamins / metabolism
Source: Web Of Science
Added: August 6, 2018

2015 journal article

A new method for detecting associations with rare copy-number variants

PLoS Genetics, 11(10).

By: J. Tzeng, P. Magnusson, P. Sullivan & J. Szatkiewicz

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

A penalized likelihood approach for investigating gene-drug interactions in pharmacogenetic studies

BIOMETRICS, 71(2), 529–537.

By: M. Neely*, H. Bondell n & J. Tzeng n

author keywords: Association analysis; Haplotype; Individualized medicine; Multiple comparisons; Penalized regression; Pharmacogenetics
MeSH headings : Antineoplastic Agents / adverse effects; Biometry; Computer Simulation; Female; Genes, bcl-2; Haplotypes; Humans; Likelihood Functions; Models, Statistical; Ovarian Neoplasms / drug therapy; Ovarian Neoplasms / genetics; Pharmacogenetics / statistics & numerical data; Regression Analysis
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Assessing gene-environment interactions for common and rare variants with binary traits using gene-trait similarity regression

Genetics, 199(3), 695-.

By: G. Zhao, R. Marceau, D. Zhang & J. Tzeng

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Complete Effect-Profile Assessment in Association Studies With Multiple Genetic and Multiple Environmental Factors

GENETIC EPIDEMIOLOGY, 39(2), 122–133.

By: Z. Wang n, A. Maity n, Y. Luo n, M. Neely* & J. Tzeng n

Contributors: Z. Wang n, A. Maity n, Y. Luo n, M. Neely* & J. Tzeng n

author keywords: factor-set association analysis; kernel machine regression; genetic-environmental interactions; joint and conditional tests
MeSH headings : Computer Simulation; Environment; Gene-Environment Interaction; Genetic Predisposition to Disease; Genome-Wide Association Study / methods; Humans; Models, Genetic; Software
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

The American Journal of Human Genetics, 96(2), 283–294.

By: R. Maier*, G. Moser*, G. Chen*, S. Ripke*, W. Coryell*, J. Potash*, W. Scheftner*, J. Shi* ...

co-author countries: Australia 🇦🇺 Sweden 🇸🇪
MeSH headings : Bipolar Disorder / genetics; Depressive Disorder, Major / genetics; Genetic Testing / methods; Genetics, Medical / methods; Humans; Linear Models; Mental Disorders / genetics; Multifactorial Inheritance / genetics; Multivariate Analysis; Polymorphism, Single Nucleotide / genetics; Risk Assessment / methods; Schizophrenia / genetics
Source: Crossref
Added: February 24, 2020

2015 journal article

Module-based association analysis for omics data with network structure

PLoS One, 10(3).

By: Z. Wang, A. Maity, C. Hsiao, D. Voora, R. Kaddurah-Daouk & J. Tzeng

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Proper Use of Allele-Specific Expression Improves Statistical Power for cis-eQTL Mapping with RNA-Seq Data

JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 110(511), 962–974.

By: Y. Hu, W. Sun, J. Tzeng* & C. Perou

author keywords: ASE; eQTL study; Gene expression; Haplotype; Maximum likelihood
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Nature Neuroscience, 18(2), 199–209.

By: J. Tzeng*

MeSH headings : Brain / immunology; Brain / metabolism; Databases, Genetic; Genetic Predisposition to Disease / genetics; Genome-Wide Association Study / methods; Histones / genetics; Histones / metabolism; Humans; Mental Disorders / etiology; Mental Disorders / genetics; Signal Transduction / genetics
Source: Crossref
Added: December 29, 2020

2015 journal article

Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Nature Neuroscience, 18(2), 199–209.

By: C. O'Dushlaine, L. Rossin, P. Lee, L. Duncan, N. Parikshak, S. Newhouse, S. Ripke, B. Neale ...

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Analysis of Gene-Gene Interactions Using Gene-Trait Similarity Regression

HUMAN HEREDITY, 78(1), 17–26.

By: X. Wang n, M. Epstein* & J. Tzeng n

co-author countries: Japan 🇯🇵 Taiwan, Province of China 🇹🇼
author keywords: Gene-gene interactions; Gene-trait similarity; Similarity regression
MeSH headings : Algorithms; Computer Simulation; Epistasis, Genetic; Genotype; Humans; Models, Genetic; Polymorphism, Single Nucleotide; Principal Component Analysis; Regression Analysis
Source: Web Of Science
Added: August 6, 2018

2014 journal article

GENE-LEVEL PHARMACOGENETIC ANALYSIS ON SURVIVAL OUTCOMES USING GENE-TRAIT SIMILARITY REGRESSION

ANNALS OF APPLIED STATISTICS, 8(2), 1232–1255.

By: J. Tzeng n, W. Lu n & F. Hsu*

author keywords: Association study; gene/pathway; pharmacogenetics; similarity regression; survival data; proportional odds model; proportional hazards model
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Heritability and genomics of gene expression in peripheral blood

Nature Genetics, 46(5), 430–437.

By: F. Wright n, P. Sullivan*, A. Brooks*, F. Zou*, W. Sun*, K. Xia*, V. Madar*, R. Jansen* ...

co-author countries: Netherlands 🇳🇱
MeSH headings : Blood / metabolism; Gene Expression Profiling; Gene Expression Regulation / genetics; Genotype; Humans; Inheritance Patterns / genetics; Likelihood Functions; Netherlands; Polymorphism, Single Nucleotide / genetics; Quantitative Trait Loci / genetics
Source: Crossref
Added: February 5, 2020

2014 journal article

Heritability and genomics of gene expression in peripheral blood

Nature Genetics, 46(5), 430–437.

By: F. Wright, P. Sullivan, A. Brooks, F. Zou, W. Sun, K. Xia, V. Madar, R. Jansen ...

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Integrative gene set analysis of multi-platform data with sample heterogeneity

BIOINFORMATICS, 30(11), 1501–1507.

By: J. Hu n & J. Tzeng n

co-author countries: Taiwan, Province of China 🇹🇼
MeSH headings : Breast Neoplasms / genetics; DNA Copy Number Variations; DNA Methylation; Female; Gene Expression Profiling; Genes; Genomics / methods; Humans; Sequence Analysis, RNA; Statistics, Nonparametric
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Pathway-Guided Identification of Gene-Gene Interactions

ANNALS OF HUMAN GENETICS, 78(6), 478–491.

By: X. Wang n, D. Zhang n & J. Tzeng n

co-author countries: Taiwan, Province of China 🇹🇼
author keywords: Pathway analysis; gene-gene interactions; bio-knowledge-guided
MeSH headings : Computer Simulation; Epistasis, Genetic; Genotype; Humans; Linear Models; Models, Genetic; Polymorphism, Single Nucleotide; Principal Component Analysis; Regression Analysis
Source: Web Of Science
Added: August 6, 2018

2013 journal article

A mega-analysis of genome-wide association studies for major depressive disorder

Molecular Psychiatry, 18(4), 497–511.

By: P. Sullivan, M. Daly, S. Ripke, C. Lewis, D. Lin, N. Wray, B. Neale, D. Levinson ...

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Nature Genetics, 45(9), 984–994.

By: J. Tzeng*

MeSH headings : Adult; Attention Deficit Disorder with Hyperactivity / genetics; Bipolar Disorder / genetics; Child; Child Development Disorders, Pervasive / genetics; Crohn Disease / genetics; Depressive Disorder, Major / genetics; Genetic Heterogeneity; Genetic Predisposition to Disease; Genome, Human; Genome-Wide Association Study; Humans; Inheritance Patterns; Mental Disorders / genetics; Polymorphism, Single Nucleotide; Schizophrenia / genetics
Source: Crossref
Added: December 29, 2020

2013 journal article

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Nature Genetics, 45(9), 984-.

By: S. Lee, S. Ripke, B. Neale, S. Faraone, S. Purcell, R. Perlis, B. Mowry, A. Thapar ...

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Multivariate Phenotype Association Analysis by Marker-Set Kernel Machine Regression

GENETIC EPIDEMIOLOGY, 36(7), 686–695.

By: A. Maity n, P. Sullivan* & J. Tzeng n

Contributors: A. Maity n, P. Sullivan* & J. Tzeng n

author keywords: kernel machine regression; multivariate regression; multivariate phenotypes; score-based test
MeSH headings : Antipsychotic Agents / therapeutic use; Chromosomes, Human, Pair 6; Computer Simulation; Genetic Markers; Genome-Wide Association Study; Herpesviridae Infections / genetics; Herpesviridae Infections / immunology; Herpesviridae Infections / virology; Humans; Models, Genetic; Models, Statistical; Multivariate Analysis; Phenotype; Polymorphism, Single Nucleotide; Regression Analysis; Schizophrenia / drug therapy; Schizophrenia / genetics; Schizophrenia / virology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Combining an evolution-guided clustering algorithm and haplotype-based LRT in family association studies

BMC Genetics, 12.

By: M. Lee, J. Tzeng, S. Huang & C. Hsiao

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Studying Gene and Gene-Environment Effects of Uncommon and Common Variants on Continuous Traits: A Marker-Set Approach Using Gene-Trait Similarity Regression

AMERICAN JOURNAL OF HUMAN GENETICS, 89(2), 277–288.

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
MeSH headings : Chromosomes, Human, Pair 21 / genetics; Computer Simulation; Databases, Genetic; Environment; Genes / genetics; Genetic Markers; Humans; Models, Genetic; Mutation / genetics; Quantitative Trait, Heritable; Regression Analysis
Source: Web Of Science
Added: August 6, 2018

2010 journal article

A quality control algorithm for filtering SNPs in genome-wide association studies

BIOINFORMATICS, 26(14), 1731–1737.

By: M. Pongpanich n, P. Sullivan n & J. Tzeng n

MeSH headings : Algorithms; Genome; Genome-Wide Association Study / methods; Genome-Wide Association Study / standards; Polymorphism, Single Nucleotide; Quality Control
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Evaluating Haplotype Effects in Case-Control Studies via Penalized-Likelihood Approaches: Prospective or Retrospective Analysis?

GENETIC EPIDEMIOLOGY, 34(8), 892–911.

By: M. Koehler n, H. Bondell n & J. Tzeng n

author keywords: haplotype-based association analysis; variable selection; regularized regression; prospective likelihood; retrospective likelihood
MeSH headings : Algorithms; Case-Control Studies; Computer Simulation; Genes, Dominant; Genes, Recessive; Genotype; Haplotypes / genetics; Humans; Likelihood Functions; Models, Genetic; Prospective Studies; Regression Analysis; Retrospective Studies
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Haplotype-Based Pharmacogenetic Analysis for Longitudinal Quantitative Traits in the Presence of Dropout

JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 20(2), 334–350.

By: J. Tzeng n, W. Lu n, M. Farmen*, Y. Liu* & P. Sullivan*

author keywords: Adaptive LASSO; Haplotype-based association analysis; Haplotype-treatment interaction; Missing data; Repeated outcome; Variable selection
MeSH headings : Antipsychotic Agents / therapeutic use; Computer Simulation; Data Interpretation, Statistical; Genetic Predisposition to Disease; Haplotypes; Humans; Likelihood Functions; Longitudinal Studies; Models, Statistical; Patient Dropouts / statistics & numerical data; Pharmacogenetics / statistics & numerical data; Phenotype; Quantitative Trait, Heritable; Randomized Controlled Trials as Topic / statistics & numerical data; Reproducibility of Results; Schizophrenia / drug therapy; Schizophrenia / genetics; Treatment Outcome
Source: Web Of Science
Added: August 6, 2018

2009 journal article

A Regression-based Association Test for Case-control Studies that Uses Inferred Ancestral Haplotype Similarity

ANNALS OF HUMAN GENETICS, 73, 520–526.

By: Y. Liu n, Y. Li*, G. Satten*, A. Allen* & J. Tzeng n

author keywords: Case-control studies; haplotype similarity; haplotype sharing; haplotype-based association test; covariates; regression-based association analysis
MeSH headings : Case-Control Studies; Computer Simulation; Gene Frequency; Genetic Techniques; Genome, Human; Haplotypes; Humans; Linkage Disequilibrium; Models, Genetic; Polymorphism, Single Nucleotide; Regression Analysis
Source: Web Of Science
Added: August 6, 2018

2009 journal article

A comprehensive approach to haplotype-specific analysis by penalized likelihood

European Journal of Human Genetics, 18(1), 95–103.

By: J. Tzeng n & H. Bondell n

MeSH headings : Computer Simulation; Haplotypes / genetics; Humans; Likelihood Functions; Models, Statistical; Quantitative Trait, Heritable
Source: Crossref
Added: August 28, 2020

2009 journal article

Erratum: Genomewide association for schizophrenia in the CATIE study: results of stage 1

Molecular Psychiatry, 14(12), 1144–1144.

By: P. Sullivan, D. Lin, J. Tzeng*, E. van den Oord, D. Perkins, T. Stroup, M. Wagner, S. Lee ...

Source: Crossref
Added: February 24, 2020

2009 journal article

Gene-Trait Similarity Regression for Multimarker-Based Association Analysis

Biometrics, 65(3), 822–832.

By: J. Tzeng n, D. Zhang n, S. Chang*, D. Thomas* & M. Davidian n

co-author countries: Taiwan, Province of China 🇹🇼
MeSH headings : Chromosome Mapping / methods; Computer Simulation; Genetic Linkage / genetics; Genetic Markers / genetics; Haplotypes / genetics; Humans; Models, Genetic; Models, Statistical; Quantitative Trait Loci / genetics; Regression Analysis
Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2009 review

Genome-wide association for major depressive disorder: A possible role for the presynaptic protein piccolo

[Review of ]. Molecular Psychiatry, 14(4), 359–375.

By: P. Sullivan, E. Geus, G. Willemsen, M. James, J. Smit, T. Zandbelt, V. Arolt, B. Baune ...

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

Molecular Psychiatry, 14(4), 359–375.

By: P. Sullivan*, E. de Geus, G. Willemsen, M. James*, J. Smit*, T. Zandbelt*, V. Arolt*, B. Baune* ...

co-author countries: Australia 🇦🇺 Germany 🇩🇪 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Netherlands 🇳🇱
author keywords: major depressive disorder; genome-wide association; Netherlands study of depression and anxiety; Netherlands twin registry
MeSH headings : Adult; Case-Control Studies; Cohort Studies; Cytoskeletal Proteins / genetics; Depressive Disorder, Major / genetics; Female; Genetic Linkage; Genetic Predisposition to Disease; Genome-Wide Association Study / methods; Humans; Male; Middle Aged; Neuropeptides / genetics; Polymorphism, Single Nucleotide / genetics
Source: Crossref
Added: August 28, 2020

2008 journal article

Genomewide association for schizophrenia in the CATIE study: results of stage 1

Molecular Psychiatry, 13(6), 570–584.

By: P. Sullivan*, D. Lin*, J. Tzeng n, E. van den Oord*, D. Perkins*, T. Stroup*, M. Wagner*, S. Lee* ...

author keywords: schizophrenia; genomewide association; CATIE
MeSH headings : Antipsychotic Agents / therapeutic use; Case-Control Studies; Computational Biology; DNA / genetics; DNA / isolation & purification; Genetic Markers; Genetic Variation; Genome, Human; Genotype; Humans; National Institute of Mental Health (U.S.); Polymorphism, Single Nucleotide; Schizophrenia / drug therapy; Schizophrenia / genetics; United States
Sources: Web Of Science, Crossref
Added: August 6, 2018

2007 journal article

Haplotype-based association analysis via variance-components score test

AMERICAN JOURNAL OF HUMAN GENETICS, 81(5), 927–938.

By: J. Tzeng n & D. Zhang n

MeSH headings : Amyotrophic Lateral Sclerosis / genetics; Computer Simulation; Databases, Genetic; Genetic Predisposition to Disease; Haplotypes; Humans; Likelihood Functions; Models, Genetic; Polymorphism, Single Nucleotide / genetics; Quantitative Trait, Heritable
Source: Web Of Science
Added: August 6, 2018

2006 journal article

A two-stage design for multiple testing in large-scale association studies

JOURNAL OF HUMAN GENETICS, 51(6), 523–532.

By: S. Wen*, J. Tzeng n, J. Kao* & C. Hsiao*

co-author countries: Taiwan, Province of China 🇹🇼
author keywords: association studies; cost-effectiveness; false positive rate; multiple testing; two-stage design
MeSH headings : Cost-Benefit Analysis; Data Interpretation, Statistical; False Positive Reactions; Genetic Markers; Genetic Techniques; Genotype; Humans; Hyperlipoproteinemia Type IV / genetics; Models, Genetic; Polymorphism, Single Nucleotide
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Likelihood-based inference on haplotype effects in genetic association studies - Comment

Journal of the American Statistical Association, 101(473), 111–114.

By: J. Tzeng & K. Roeder

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Regression-based association analysis with clustered haplotypes through use of genotypes

AMERICAN JOURNAL OF HUMAN GENETICS, 78(2), 231–242.

By: J. Tzeng n, C. Wang*, J. Kao* & C. Hsiao*

co-author countries: Taiwan, Province of China 🇹🇼
MeSH headings : Apolipoprotein A-V; Apolipoproteins A / genetics; Cluster Analysis; Computer Simulation; Genetic Linkage; Genotype; Haplotypes / genetics; Humans; Hypertriglyceridemia / genetics; Regression Analysis
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Evolutionary-based grouping of haplotypes in association analysis

GENETIC EPIDEMIOLOGY, 28(3), 220–231.

By: J. Tzeng n

author keywords: evolutionary-based clustering; dimension reduction of haplotypes; haplotype tests for association
MeSH headings : Algorithms; Genetic Predisposition to Disease / genetics; Genotype; Haplotypes / genetics; Humans; Models, Genetic; Polymorphism, Single Nucleotide / genetics
Source: Web Of Science
Added: August 6, 2018

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