Jieping Zhao

Works (2)

Updated: July 5th, 2023 15:57

2007 journal article

Molecular architecture of the DNA-binding region and its relationship to classification of basic helix-loop-helix proteins

MOLECULAR BIOLOGY AND EVOLUTION, 24(1), 192–202.

By: W. Atchley n & J. Zhao n

author keywords: computational biology; bHLH proteins; molecular architecture; multivariate statistics; DNA-binding specificity; molecular evolution
MeSH headings : Animals; Basic Helix-Loop-Helix Transcription Factors / chemistry; Basic Helix-Loop-Helix Transcription Factors / classification; Basic Helix-Loop-Helix Transcription Factors / genetics; Basic Helix-Loop-Helix Transcription Factors / metabolism; Binding Sites; Codon / genetics; DNA / metabolism; Dimerization; Humans; Hydrophobic and Hydrophilic Interactions; Protein Structure, Secondary; Protein Structure, Tertiary; Static Electricity
TL;DR: Using multivariate statistical analyses, discriminant analyses describe the multidimensional aspects of physiochemical variation and clarify the structural basis of the prevailing evolutionary classification of basic helix-loop-helix proteins. (via Semantic Scholar)
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10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Solving the protein sequence metric problem

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(18), 6395–6400.

By: W. Atchley n, J. Zhao n, A. Fernandes n & T. Druke n

author keywords: basic helix-loop-helix; molecular evolution; multivariate statistics; amino acid attributes; factor analysis
MeSH headings : Amino Acid Sequence / genetics; Analysis of Variance; Cluster Analysis; Codon / genetics; Computational Biology / methods; Discriminant Analysis; Genetic Variation; Models, Genetic; Multivariate Analysis; Phylogeny; Protein Conformation; Static Electricity; Statistics as Topic / methods
TL;DR: Multivariate statistical analyses on almost 500 amino acid attributes are used to produce a small set of highly interpretable numeric patterns of amino acid variability that reflect polarity, secondary structure, molecular volume, codon diversity, and electrostatic charge. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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