Karen Anna Von Dollen

Works (5)

Updated: July 5th, 2023 15:32

2020 journal article

Metabolomic Profile of Allantoic and Amniotic Fluid in Late-term Gestational Mares Characterized by H-1-nuclear Magnetic Resonance Spectroscopy

JOURNAL OF EQUINE VETERINARY SCIENCE, 94.

By: T. Beachler n, C. Bailey n, H. Gracz n, D. Morgan n, K. Von Dollen n, K. Ellis n, J. Gadsby n , S. Lyle n

author keywords: Equine; Metabolomics; Allantoic; Amniotic; Nuclear magnetic resonance spectroscopy
MeSH headings : Allantois; Amniotic Fluid; Animals; Body Fluids; Female; Horses; Magnetic Resonance Spectroscopy; Pregnancy; Protons
TL;DR: The goal of this study was to characterize the global metabolomic profile of equine allantoic and amniotic fluid through nuclear magnetic resonance spectroscopy offetal fluids from 12 pregnancies through ultrasound-guided transabdominal puncture. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 24, 2020

2020 journal article

Plasma metabolomic profiling of healthy pregnant mares and mares with experimentally induced placentitis

Equine Veterinary Journal, 53(1), 85–93.

By: T. Beachler n, H. Gracz n, D. Morgan n, S. Bembenek Bailey  n, L. Borst n , K. Ellis n, K. Von Dollen n, S. Lyle n ...

author keywords: horse; placentitis; diagnosis; plasma; NMR spectroscopy; metabolomics
MeSH headings : Animals; Female; Horse Diseases; Horses; Metabolomics; Placenta Diseases / veterinary; Plasma; Pregnancy; Streptococcus equi
TL;DR: Two phases of metabolite changes were noted after experimental infection: An immediate rise in metabolite concentration involved in energy, nitrogen, hydrogen, and oxygen metabolism within 4 hours after inoculation that was followed by a decrease in metabolites involved inenergy and nitrogen metabolism at 4 days, coinciding with ultrasonographic diagnosis of placentitis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: April 27, 2020

2019 journal article

Antimicrobial Activity of Ceftiofur and Penicillin With Gentamicin Against Escherichia coli and Streptococcus equi Subspecies zooepidemicus in an Ex Vivo Model of Equine Postpartum Uterine Disease

JOURNAL OF EQUINE VETERINARY SCIENCE, 79, 121–126.

By: K. Von Dollen n, M. Jones n, T. Beachler n, T. Harris n, M. Papich n , S. Lyle n, C. Bailey n

author keywords: E. coli; S. zooepidemicus; Postpartum mare; Antibiotic use
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Cephalosporins; Drug Resistance, Bacterial; Escherichia coli; Female; Gentamicins; Horse Diseases / drug therapy; Horses; Humans; Penicillins; Postpartum Period; Streptococcus equi; Uterine Diseases / drug therapy; Uterine Diseases / veterinary
TL;DR: The intrauterine infusion of procaine penicillin G with gentamicin in cases of postpartum uterine disease caused by E. coli or S. zooepidemicus is supported by the results of this work. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 26, 2019

2018 journal article

Allantoic Metabolites, Progesterone, and Estradiol-17 beta Remain Unchanged After Infection in an Experimental Model of Equine Ascending Placentitis

JOURNAL OF EQUINE VETERINARY SCIENCE, 73, 95–105.

By: T. Beachler n, H. Gracz n, N. Long *, L. Borst n , D. Morgan n, A. Nebel n, N. Andrews n, J. Koipillai n ...

author keywords: Equine; Ascending placentitis; Metabolomics; Allantoic fluid
TL;DR: The results of this study established a database of equine allantoic fluid metabolites and confirmed the utility of uteroplacental ultrasound for detection of placentitis before the onset of hematologic changes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: February 11, 2019

2018 journal article

Pharmacokinetics of Intrarectal Altrenogest in Horses

JOURNAL OF EQUINE VETERINARY SCIENCE, 72, 41–46.

By: K. Ellis n, R. Council-Troche *, K. Von Dollen n, T. Beachler n, C. Bailey n, J. Davis*, S. Lyle n

author keywords: Horse; Altrenogest; Pharmacokinetics; Intrarectal administration
MeSH headings : Administration, Rectal; Animals; Cross-Over Studies; Female; Horses / metabolism; Pregnancy; Pregnancy Maintenance / drug effects; Trenbolone Acetate / analogs & derivatives; Trenbolone Acetate / pharmacokinetics
TL;DR: Altrenogest is rapidly absorbed following PR administration in the horse and reaches therapeutic concentrations, making this a viable method of treatment in NPO mares, and the decreased bioavailability and shorter detection time suggest 0.088 mg/kg PR q 4–8 hours would be necessary to maintain therapeutic concentrations over a 24‐hour period. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: January 7, 2019

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