Kathlyne Bautista

College of Engineering

Works (5)

Updated: April 23rd, 2025 20:22

2024 article

Low-boiling-point perfluorocarbon nanodroplets for adaptable ultrasound-induced blood-brain barrier opening

Dauba, A., Spitzlei, C., Bautista, K. J. B., Jourdain, L., Selingue, E., VanTreeck, K. E., … Novell, A. (2024, October 23). Journal of Controlled Release.

By: A. Dauba *, C. Spitzlei*, K. Bautista n, L. Jourdain*, E. Selingue *, K. VanTreeck n, J. Mattern n, C. Denis* ...

author keywords: USA; Blood-brain barrier; Focused ultrasound; Nanodroplets; Perfluorocarbon; Drug delivery
MeSH headings : Blood-Brain Barrier / metabolism; Fluorocarbons / chemistry; Animals; Microbubbles; Nanoparticles / chemistry; Ultrasonic Waves; Mice; Male; Contrast Media / chemistry; Phospholipids / chemistry
topics (OpenAlex): Ultrasound and Hyperthermia Applications; Photoacoustic and Ultrasonic Imaging; Ultrasound Imaging and Elastography
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6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: November 12, 2024

2024 journal article

Rotational Intravascular Multidirectional Ultrasound Catheter for Sonothrombolysis of Retracted Clots: An in Vitro and in Vivo Study

Engineering, 42, 235–243.

By: H. Wu n, J. Kim*, B. Zhang n , G. Owens *, G. Stocker *, M. Chen n, B. Kreager n, A. Cornett * ...

author keywords: Intravascular ultrasound catheter; Sonothrombolysis in vivo; Retracted clots thrombolysis
topics (OpenAlex): Venous Thromboembolism Diagnosis and Management; Diagnosis and Treatment of Venous Diseases; Pain Management and Treatment
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Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: September 15, 2024

2023 article

Current Status of Sub-micron Cavitation-Enhancing Agents for Sonothrombolysis

Bautista, K. J. B., Kim, J., Xu, Z., Jiang, X., & Dayton, P. A. (2023, March 1). Ultrasound in Medicine & Biology, Vol. 49, pp. 1049–1057.

By: K. Bautista n, J. Kim n, Z. Xu *, X. Jiang n  & P. Dayton n

author keywords: Thrombosis; Sonothrombolysis; Cavitation; Phase-change nanodroplets; Nanoparticles; Nanoemulsions; Contrast agents
MeSH headings : Humans; Ultrasonography; Thrombosis / drug therapy; Ultrasonic Therapy; Fibrinolytic Agents / therapeutic use; High-Intensity Focused Ultrasound Ablation; Mechanical Thrombolysis; Microbubbles; Thrombolytic Therapy
topics (OpenAlex): Ultrasound and Hyperthermia Applications; Ultrasound and Cavitation Phenomena; Photoacoustic and Ultrasonic Imaging
TL;DR: In this article, the applications of different sub-micron particles for sonothrombolysis are discussed and in vitro and in vivo studies that apply these particles as cavitation agents and as adjuvants to thrombotic drugs are reviewed. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 24, 2023

2022 article

Performance Assessment of Ultra-Wideband and Dual-Mode 1D CMUT Arrays for Acoustic Angiography

Belekov, E., Bautista, K. J., Annayev, M., Adelegan, O. J., Biliroglu, A. O., Kierski, T. M., … Oralkan, O. (2022, October 10). 2022 IEEE International Ultrasonics Symposium (IUS).

By: E. Belekov n, K. Bautista*, M. Annayev n, O. Adelegan n, A. Biliroglu n, T. Kierski*, J. Sanders n, R. Kemal n ...

author keywords: capacitive micromachined ultrasonic transducer; ultra-wideband; dual-mode; acoustic angiography; ultrasound handheld probe; contrast agent
topics (OpenAlex): Photoacoustic and Ultrasonic Imaging; Ultrasound and Hyperthermia Applications; Ultrasound Imaging and Elastography
TL;DR: A custom 256-channel imaging probe with integrated low-noise amplifiers and supporting power circuitry is designed with a strong use case for the UWB and dual-mode CMUT arrays in acoustic angiography applications. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: February 6, 2023

2021 journal article

An Analysis of Sonothrombolysis and Cavitation for Retracted and Unretracted Clots Using Microbubbles Versus Low-Boiling-Point Nanodroplets

IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 69(2), 711–719.

By: J. Kim*, K. Bautista*, R. Deruiter*, L. Goel*, X. Jiang n , Z. Xu *, P. Dayton*

author keywords: Ultrasonic imaging; Acoustics; Medical treatment; Frequency control; Coagulation; Transducers; Surface treatment; Cavitation; microbubble (MB); nanodroplet (ND); retracted clot; sonothrombolysis; thrombosis
MeSH headings : Aged; Blood Coagulation; Humans; Microbubbles; Thrombosis / diagnostic imaging; Thrombosis / therapy; Ultrasonic Therapy / methods
topics (OpenAlex): Ultrasound and Hyperthermia Applications; Ultrasound and Cavitation Phenomena; Photoacoustic and Ultrasonic Imaging
TL;DR: It is concluded that ND-mediated sonothrombolysis outperforms MB-mediated therapy regardless of clot retraction, and this advantage of ND- mediated cavitation is emphasized for retracted clots. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: February 14, 2022

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