Ke Cheng
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Works (134)
Updated: November 8th, 2023 05:01
2023 journal article
A SARS-CoV-2 and influenza double hit vaccine based on RBD-conjugated inactivated influenza A virus
SCIENCE ADVANCES, 9(25).
co-author countries:
United States of America 🇺🇸
MeSH headings : Cricetinae; Animals; Humans; Mice; Influenza Vaccines; SARS-CoV-2; Influenza, Human; Influenza A Virus, H1N1 Subtype; Pandemics; COVID-19 / prevention & control; COVID-19 Vaccines; Influenza A virus
www.science.org (publisher PDF)
Sources: Web Of Science, ORCID
Added: June 24, 2023
2023 journal article
An inhaled bioadhesive hydrogel to shield non-human primates from SARS-CoV-2 infection
Nature Materials, 2.
co-author countries:
United States of America 🇺🇸
Sources: Web Of Science, ORCID, Crossref
Added: March 6, 2023
2023 journal article
Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentials
NANO RESEARCH, 16(5), 7248–7259.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: nanovesicles (NVs); exosomes; cardiac repair; mesenchymal stem cells (MSCs); extracellular vesicles (EVs); myocardial infarction (Ml)
Sources: Web Of Science, ORCID
Added: August 28, 2023
2023 journal article
Intrapericardial long non-coding RNA–Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair
European Heart Journal, 44(19), 1748–1760.
co-author countries:
United States of America 🇺🇸
author keywords: Myocardial infarction; Adverse remodelling; Mesenchymal stem cell; EVs; lncRNA; Tcf21
MeSH headings : Mice; Animals; Swine; RNA, Long Noncoding / genetics; RNA, Long Noncoding / metabolism; RNA, Antisense / genetics; RNA, Antisense / metabolism; Ventricular Remodeling; Myocardial Infarction / genetics; Myocardial Infarction / therapy; Myocardial Infarction / metabolism; Fibrosis; Demethylation
Sources: Web Of Science, ORCID, Crossref
Added: April 4, 2023
2023 article
Microneedle Patch Delivery of PROTACs for Anti-Cancer Therapy
Cheng, X., Hu, S., & Cheng, K. (2023, June 9). ACS NANO, Vol. 6.
co-author countries:
United States of America 🇺🇸
author keywords: PROTAC; estrogen receptor; microneedle patch; hyaluronic acid gel; ER-positive breast cancer
MeSH headings : Humans; Female; Estrogen Receptor alpha / metabolism; Proteolysis Targeting Chimera; Breast Neoplasms / pathology; Drug Delivery Systems / methods; Proteolysis
Sources: Web Of Science, ORCID
Added: June 26, 2023
2023 article
Pericardial Delivery of SDF-1 α Puerarin Hydrogel Promotes Heart Repair and Electrical Coupling
Luo, L., Li, Y., Bao, Z., Zhu, D., Chen, G., Li, W., … Li, Z. (2023, September 15). ADVANCED MATERIALS, Vol. 9.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: cardiac arrhythmias; electrical coupling; endogenous repair; inflammation regulation; myocardial infarction; SDF-1
Sources: Web Of Science, ORCID
Added: October 23, 2023
2023 journal article
Tissue clearing and three-dimensional imaging of the whole cochlea and vestibular system from multiple large-animal models
STAR PROTOCOLS, 4(2).
co-author countries:
United States of America 🇺🇸
author keywords: imaged cochleae using open -source software.; several mm; larger animal inner; open -source software
Source: Web Of Science
Added: September 5, 2023
2023 article
Wound-triggered shape change microgels for the development of enhanced biomimetic function platelet-like particles
Chee, E., Mihalko, E., Nellenbach, K., Sollinger, J., Huang, K., Hon, M., … Brown, A. (2023, October 17). JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, Vol. 10.
co-author countries:
United States of America 🇺🇸
author keywords: fibrin; hemostasis; synthetic platelet; trauma; wound healing
Sources: Web Of Science, ORCID
Added: November 6, 2023
2022 article
Decoy Exosomes Offer Protection Against Chemotherapy-Induced Toxicity
Fan, M., Li, H., Shen, D., Wang, Z., Liu, H., Zhu, D., … Li, Z. (2022, September 4). ADVANCED SCIENCE, Vol. 9.
co-author countries:
China 🇨🇳 United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: cardio-oncology; cardiotoxicity; chemotherapy; exosome; tetrahedral DNA nanostructure
MeSH headings : Humans; Exosomes / genetics; Exosomes / metabolism; Cardiotoxicity / etiology; Cardiotoxicity / prevention & control; Cardiotoxicity / metabolism; Quality of Life; Neoplasms; Antineoplastic Agents / toxicity; Antineoplastic Agents / metabolism; Chemical and Drug Induced Liver Injury / metabolism
Sources: Web Of Science, ORCID
Added: September 12, 2022
2022 article
Detachable Microneedle Patches Deliver Mesenchymal Stromal Cell Factor-Loaded Nanoparticles for Cardiac Repair
Hu, S., Zhu, D., Li, Z., & Cheng, K. (2022, September 23). ACS NANO, Vol. 9.
co-author countries:
United States of America 🇺🇸
author keywords: mesenchymal stromal cell; secreted factors; microneedle patch; elastin-like peptide gel; hyaluronic acid gel; myocardial infarction; cardiac repair
MeSH headings : Animals; Rats; Elastin; Polylactic Acid-Polyglycolic Acid Copolymer; Hyaluronic Acid; Mesenchymal Stem Cells; Myocytes, Cardiac; Myocardium; Nanoparticles; Peptides
Sources: Web Of Science, ORCID
Added: October 11, 2022
2022 journal article
Engineering stem cell therapeutics for cardiac repair
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 171, 56–68.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Stem cell engineering; Genetic engineering; Micro; nanotechnology; Cardiovascular bioengineering
MeSH headings : Biocompatible Materials; Heart; Humans; Hydrogels; Stem Cells; Tissue Engineering / methods
Source: Web Of Science
Added: August 22, 2022
2022 article
Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine
Wang, Z., Popowski, K. D., Zhu, D., Abad, B. L. de J., Wang, X., Liu, M., … Cheng, K. (2022, July 4). NATURE BIOMEDICAL ENGINEERING, Vol. 7.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Antibodies, Neutralizing; CD8-Positive T-Lymphocytes; COVID-19 / prevention & control; COVID-19 Vaccines; Exosomes; Humans; Mice; Mice, Inbred BALB C; SARS-CoV-2; Viral Vaccines
Sources: Web Of Science, ORCID
Added: July 11, 2022
2022 journal article
Gecko-Inspired Adhesives with Asymmetrically Tilting-Oriented Micropillars
LANGMUIR, 38(29).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Adhesiveness; Adhesives; Animals; Finite Element Analysis; Lizards; Locomotion
Source: Web Of Science
Added: August 1, 2022
2022 journal article
Inhalable dry powder mRNA vaccines based on extracellular vesicles
Matter, 5(9), 2960–2974.
co-author countries:
United States of America 🇺🇸
Sources: Web Of Science, ORCID, Crossref
Added: October 17, 2022
2022 journal article
Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3
CIRCULATION RESEARCH, 131(10), E135–E150.
co-author countries:
United States of America 🇺🇸
author keywords: exosomes; immunomodulation; mesesnchymal stem cell; myocardial infarction; regulatory T cell
MeSH headings : Humans; Exosomes / metabolism; Forkhead Box Protein O3 / genetics; Forkhead Box Protein O3 / metabolism; Mesenchymal Stem Cells / metabolism; Myocardial Infarction / pathology; Proto-Oncogene Proteins c-akt / metabolism; Signal Transduction; Heart Injuries / metabolism
Sources: Web Of Science, ORCID
Added: November 14, 2022
2022 journal article
Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem cells in myocardial infarction
CHEMICAL ENGINEERING JOURNAL, 427.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Mesenchymal stem cells; Hydrogel; Myocardial infarction; Intrapericardial; Intramyocardial
Sources: Web Of Science, ORCID
Added: January 3, 2022
2022 journal article
Nanoparticles functionalized with stem cell secretome and CXCR4-overexpressing endothelial membrane for targeted osteoporosis therapy
JOURNAL OF NANOBIOTECHNOLOGY, 20(1).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
Contributors: C. Zhang n, W. Zhang *, D. Zhu n , Z. Li n, Z. Wang n, J. Li n, X. Mei n, W. Xu *, n, B. Zhong*
author keywords: Osteoporosis; CXCR4; Secretome; Mesenchymal stem cells; Bone targeting; Nanoparticles
MeSH headings : Animals; Cell Membrane / chemistry; Cell Membrane / metabolism; Disease Models, Animal; Endothelial Cells / chemistry; Endothelial Cells / metabolism; Mesenchymal Stem Cells / chemistry; Mesenchymal Stem Cells / metabolism; Nanoparticle Drug Delivery System; Nanoparticles; Osteoporosis / metabolism; Rats; Receptors, CXCR4 / metabolism; Secretome / metabolism
Sources: Web Of Science, ORCID
Added: January 24, 2022
2022 journal article
Sealing the heart from the inside out
Nature Biomedical Engineering, 7(2), 87–88.
co-author countries:
United States of America 🇺🇸
Sources: Web Of Science, ORCID, Crossref
Added: February 6, 2023
2022 article
Skin-Interfaced Deep-Tissue Sensing Patch via Microneedle Waveguides
Liu, Y., Menon, R., Putcha, A., Huang, K., Bonilla, L., Vora, R., … Bai, W. (2022, June 29). ADVANCED MATERIALS TECHNOLOGIES, Vol. 6.
co-author countries:
United States of America 🇺🇸
author keywords: biosensors; microneedles; optoelectronics; waveguides; wearable devices
Sources: Web Of Science, ORCID
Added: July 5, 2022
2021 journal article
3D Bioprinting Technology – One Step Closer Towards Cardiac Tissue Regeneration
Frontiers in Materials, 8.
co-author countries:
United States of America 🇺🇸
author keywords: 3D bioprinting; scaffolds-based 3D bioprinting; 3D cardiac patch; cardiac regeneration; cardiac repair
Sources: Web Of Science, Crossref, ORCID
Added: March 7, 2022
2021 journal article
A Minimally Invasive Exosome Spray Repairs Heart after Myocardial Infarction
ACS NANO, 15(7), 11099–11111.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
Contributors: J. Yao*, K. Huang n , D. Zhu n , T. Chen *, Y. Jiang *, J. Zhang *, L. Mi*, H. Xuan
author keywords: MSC; exosome; spray; myocardial infarction; heart repair
MeSH headings : Mice; Swine; Animals; Exosomes; Myocardial Infarction / therapy; Mesenchymal Stem Cells; Heart; Disease Models, Animal
Sources: Web Of Science, ORCID
Added: August 23, 2021
2021 journal article
A Zebrafish Model of Metastatic Colonization Pinpoints Cellular Mechanisms of Circulating Tumor Cell Extravasation
FRONTIERS IN ONCOLOGY, 11.
co-author countries:
United States of America 🇺🇸
author keywords: angiopellosis; circulating tumor cell cluster; tumor cell extravasation; cancer exodus hypothesis; metastasis; osteosarcoma
Sources: Web Of Science, ORCID
Added: October 26, 2021
2021 journal article
A fluid-powered refillable origami heart pouch for minimally invasive delivery of cell therapies in rats and pigs
MED, 2(11), 1253-+.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Cell- and Tissue-Based Therapy; Heart; Mesenchymal Stem Cell Transplantation / methods; Mesenchymal Stem Cells; Myocardial Infarction / surgery; Rats; Swine
Sources: Web Of Science, ORCID
Added: November 3, 2021
2021 journal article
A stem cell-derived ovarian regenerative patch restores ovarian function and rescues fertility in rats with primary ovarian insufficiency
THERANOSTICS, 11(18), 8894–8908.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: primary ovarian insufficiency; ovarian regenerative patch; regenerative medicine; mesenchymal stem cells; acellular therapy; fertility
MeSH headings : Animals; Apoptosis; Cell-Derived Microparticles / metabolism; Disease Models, Animal; Female; Hydrogels / pharmacology; Infertility, Female / therapy; Mesenchymal Stem Cell Transplantation / methods; Mesenchymal Stem Cells / metabolism; Ovary / pathology; Primary Ovarian Insufficiency / therapy; Rats; Rats, Sprague-Dawley; Regenerative Medicine / methods; Secretome; Stem Cells / metabolism; Tissue Scaffolds
Sources: Web Of Science, ORCID
Added: October 12, 2021
2021 journal article
A trifunctional contraceptive gel enhances the safety and quality of sexual intercourse
BIOACTIVE MATERIALS, 6(6), 1777–1788.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Contraceptive; Hydrogel; Anti-viral; Libido; Erectile function
Sources: Web Of Science, ORCID
Added: March 6, 2021
2021 review
Advances in biomaterials and regenerative medicine for primary ovarian insufficiency therapy
[Review of ]. BIOACTIVE MATERIALS, 6(7), 1957–1972.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Stem cells; Primary ovarian insufficiency; Cell therapy; Biomaterials
Sources: Web Of Science, ORCID
Added: March 6, 2021
2021 review
All Roads Lead to Rome (the Heart): Cell Retention and Outcomes From Various Delivery Routes of Cell Therapy Products to the Heart
[Review of ]. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(8).
co-author countries:
United States of America 🇺🇸
author keywords: cardiac repair; cell delivery; intracoronary; intramyocardial; intrapericardial; intravenous; retention rate
MeSH headings : Animals; Cell- and Tissue-Based Therapy / methods; Heart Diseases / therapy; Humans; Injections
Sources: Web Of Science, ORCID
Added: June 10, 2021
2021 journal article
Bioengineering Technologies for Cardiac Regenerative Medicine
Frontiers in Bioengineering and Biotechnology, 9.
co-author countries:
United States of America 🇺🇸
Contributors: M. Chingale n, D. Zhu n , n & K. Huang
author keywords: bioengineering; cardiac repair; cell reprogramming; exosome; cardiac patch; targeting
Sources: Web Of Science, ORCID, Crossref
Added: June 28, 2021
2021 review
Cardiac Cell Therapy for Heart Repair: Should the Cells Be Left Out?
[Review of ]. CELLS, 10(3).
co-author countries:
United States of America 🇺🇸
Contributors: D. Zhu n & n
author keywords: stem cell; myocardial infarction; cardiovascular diseases; acellular therapy; exosomes; paracrine effects; biomedical engineering; biomaterials
MeSH headings : Cell- and Tissue-Based Therapy / methods; Heart Failure / pathology; Heart Failure / therapy; Humans; Myocardium / pathology; Myocytes, Cardiac / metabolism; Tissue Engineering / methods
Sources: Web Of Science, ORCID
Added: March 15, 2021
2021 review
Cardiac fibrosis: Myofibroblast-mediated pathological regulation and drug delivery strategies
[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 173, 504–519.
co-author countries:
United States of America 🇺🇸
author keywords: Cardiac fibrosis; Cardiac fibroblast; Myofibroblasts; Myocardial remodeling; Reprogramming; Drug delivery systems
MeSH headings : Animals; Drug Delivery Systems; Extracellular Matrix / metabolism; Extracellular Matrix / pathology; Fibrosis / metabolism; Fibrosis / pathology; Humans; Myocardium / metabolism; Myocardium / pathology; Myofibroblasts / metabolism; Myofibroblasts / pathology; Pharmaceutical Preparations / chemistry
Source: Web Of Science
Added: June 28, 2021
2021 article
Enhancement of Bone Regeneration Through the Converse Piezoelectric Effect, A Novel Approach for Applying Mechanical Stimulation
Carter, A., Popowski, K., Cheng, K., Greenbaum, A., Ligler, F. S., & Moatti, A. (2021, September 24). BIOELECTRICITY, Vol. 9.
co-author countries:
United States of America 🇺🇸
author keywords: converse piezoelectric effect; mechanical stimulation; bone regeneration
Sources: Web Of Science, ORCID
Added: September 25, 2021
2021 review
Exosome therapeutics for COVID-19 and respiratory viruses
[Review of ]. VIEW, 2(3).
co-author countries:
United States of America 🇺🇸
author keywords: COVID-19; exosomes; respiratory viruses; SARS-CoV-2
Sources: Web Of Science, ORCID
Added: July 19, 2021
2021 journal article
Exosome-eluting stents for vascular healing after ischaemic injury
NATURE BIOMEDICAL ENGINEERING, 5(10), 1174–1188.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Drug-Eluting Stents; Endothelial Cells; Endothelium, Vascular; Exosomes; Ischemia; Rats; Stents
Sources: Web Of Science, ORCID
Added: April 6, 2021
2021 journal article
Extruded Mesenchymal Stem Cell Nanovesicles Are Equally Potent to Natural Extracellular Vesicles in Cardiac Repair
ACS APPLIED MATERIALS & INTERFACES, 13(47), 55767–55779.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: extrusion; nanovesicles; extracellular vesicles; mesenchymal stem cell; ischemia reperfusion injury
MeSH headings : Animals; Disease Models, Animal; Endothelial Cells / drug effects; Endothelial Cells / pathology; Extracellular Vesicles / chemistry; Fibroblasts / drug effects; Fibroblasts / pathology; Mesenchymal Stem Cells / chemistry; Mesenchymal Stem Cells / cytology; Mice; Myocardial Infarction / drug therapy; Myocardial Infarction / pathology; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / pathology; Nanoparticles / chemistry; Particle Size; Surface Properties
Sources: Web Of Science, ORCID
Added: February 21, 2022
2021 article
Generation and Manipulation of Exosomes
CARDIAC REGENERATION, Vol. 2158, pp. 295–305.
co-author countries:
United States of America 🇺🇸
author keywords: Exosome generation; Exosome manipulation; Myocardial infarction; Cardiac homing peptide; Platelet membrane; Intravenous injection
MeSH headings : Animals; Blood Platelets / chemistry; Cell Culture Techniques / methods; Cell Fractionation / methods; Cell Membrane / chemistry; Cell Membrane / metabolism; Exosomes / ultrastructure; Humans; Mice; Molecular Targeted Therapy; Myocardium / cytology; Peptides / analysis; Peptides / metabolism; Rats; Technology, Pharmaceutical / methods; Ultracentrifugation; Ultrasonic Waves
Sources: Web Of Science, ORCID
Added: August 30, 2021
2021 article
Imaging and Isolation of Extravasation-Participating Endothelial and Melanoma Cells During Angiopellosis
MELANOMA, Vol. 2265, pp. 417–425.
co-author countries:
United States of America 🇺🇸
author keywords: Circulating tumor cells; Metastasis; Intravital microscopy; Cancer Exodus Hypothesis; Extravasation; Angiopellosis; Zebrafish; Tumor infusion; Light sheet microscopy; Tumor cell isolation
MeSH headings : Animals; Animals, Genetically Modified; Cell Line, Tumor; Endothelial Cells / metabolism; Endothelial Cells / pathology; Intravital Microscopy; Melanoma, Experimental / metabolism; Melanoma, Experimental / pathology; Neoplasm Metastasis; Neoplastic Cells, Circulating / metabolism; Neoplastic Cells, Circulating / pathology; Zebrafish
Source: Web Of Science
Added: August 30, 2021
2021 journal article
Injection of ROS-Responsive Hydrogel Loaded with Basic Fibroblast Growth Factor into the Pericardial Cavity for Heart Repair
ADVANCED FUNCTIONAL MATERIALS, 31(15).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: bFGF; heart repair; intrapericardial delivery; pericardial cavity; ROS responsive hydrogels
Sources: Web Of Science, ORCID
Added: February 22, 2021
2021 journal article
Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair
NATURE COMMUNICATIONS, 12(1).
co-author countries:
United States of America 🇺🇸
Contributors: D. Zhu n , Z. Li n, K. Huang n , T. Caranasos *, J. Rossi * & n
MeSH headings : Animals; Cardiac Surgical Procedures; Cardiovascular Agents / administration & dosage; Cell Differentiation / physiology; Drug Delivery Systems / methods; Exosomes / metabolism; Extracellular Matrix / chemistry; Hydrogels / administration & dosage; Hydrogels / chemistry; Induced Pluripotent Stem Cells / transplantation; Male; Materials Testing; Mesenchymal Stem Cells / cytology; Mice; Minimally Invasive Surgical Procedures / methods; Myocardial Infarction / drug therapy; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Myocytes, Cardiac / physiology; Pericardium; Rats; Swine
Sources: Web Of Science, ORCID
Added: March 6, 2021
2021 journal article
Platelet membrane and stem cell exosome hybrids enhance cellular uptake and targeting to heart injury
NANO TODAY, 39.
co-author countries:
United States of America 🇺🇸
author keywords: Exosomes; Targeting; Myocardial infarction; Platelet membrane; Stem cells
Sources: Web Of Science, ORCID
Added: September 7, 2021
2021 journal article
Resuscitating the Field of Cardiac Regeneration: Seeking Answers from Basic Biology
Advanced Biology, 6(2), 2101133.
co-author countries:
United States of America 🇺🇸
author keywords: cardiac hypertrophy; cardiomyogenesis; heart failure; regeneration
MeSH headings : Biology; Heart Failure / therapy; Humans; Prognosis; Regeneration; Stroke Volume; Ventricular Function, Left
Sources: Web Of Science, ORCID, Crossref
Added: January 3, 2022
2021 journal article
Self-Propelled and Near-Infrared-Phototaxic Photosynthetic Bacteria as Photothermal Agents for Hypoxia-Targeted Cancer Therapy
ACS NANO, 15(1), 1100–1110.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Drug Delivery Systems; Humans; Hyperthermia, Induced; Hypoxia; Neoplasms / drug therapy; Phototherapy
Sources: Web Of Science, ORCID
Added: March 29, 2021
2021 review
Visualizing cancer extravasation: from mechanistic studies to drug development
[Review of ]. CANCER AND METASTASIS REVIEWS, 40(1), 71–88.
co-author countries:
United States of America 🇺🇸
author keywords: Cancer metastasis; Cancer cell extravasation; Cancer models; Cancer therapies
MeSH headings : Drug Development; Humans; Neoplasm Metastasis; Neoplastic Cells, Circulating / pathology; Transendothelial and Transepithelial Migration
Source: Web Of Science
Added: November 24, 2020
2020 review
Advances of exosome isolation techniques in lung cancer
[Review of ]. MOLECULAR BIOLOGY REPORTS, 47(9), 7229–7251.
co-author countries:
Iran (Islamic Republic of) 🇮🇷 Qatar 🇶🇦 United States of America 🇺🇸
author keywords: Lung cancer; Exosome; Multi-vesicular bodies; Extracellular vesicles; MicroRNAs
MeSH headings : Biomarkers, Tumor / blood; Biomarkers, Tumor / isolation & purification; Cell-Free Nucleic Acids / blood; Cell-Free Nucleic Acids / isolation & purification; Circulating Tumor DNA / blood; Circulating Tumor DNA / isolation & purification; Exosomes / metabolism; Exosomes / pathology; Humans; Lung Neoplasms / blood; Lung Neoplasms / diagnosis; Lung Neoplasms / pathology
Source: Web Of Science
Added: August 31, 2020
2020 journal article
Atorvastatin enhances the therapeutic efficacy of mesenchymal stem cells-derived exosomes in acute myocardial infarction via up-regulating long non-coding RNA H19
CARDIOVASCULAR RESEARCH, 116(2), 353–367.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Exosomes; Atorvastatin; MSCs; lncRNA H19; Myocardial infarction
MeSH headings : Angiogenic Proteins / metabolism; Animals; Apoptosis; Atorvastatin / pharmacology; Cells, Cultured; Coculture Techniques; Disease Models, Animal; Endothelial Cells / metabolism; Endothelial Cells / pathology; Exosomes / drug effects; Exosomes / metabolism; Exosomes / transplantation; Female; Humans; Inflammation Mediators / metabolism; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / metabolism; Myocardial Infarction / genetics; Myocardial Infarction / metabolism; Myocardial Infarction / physiopathology; Myocardial Infarction / surgery; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / pathology; Neovascularization, Physiologic; RNA, Long Noncoding / genetics; RNA, Long Noncoding / metabolism; Rats, Sprague-Dawley; Recovery of Function; Up-Regulation; Ventricular Function, Left
Source: Web Of Science
Added: March 10, 2020
2020 journal article
Cardiac Stromal Cell Patch Integrated with Engineered Microvessels Improves Recovery from Myocardial Infarction in Rats and Pigs
ACS BIOMATERIALS SCIENCE & ENGINEERING, 6(11), 6309–6320.
co-author countries:
United States of America 🇺🇸
author keywords: microfluidics; cardiac patch; cardiac stromal cells; myocardial infarction; porcine model
MeSH headings : Animals; Microvessels; Myocardial Infarction / therapy; Myocytes, Cardiac; Neovascularization, Physiologic; Rats; Stromal Cells; Swine
Sources: Web Of Science, ORCID
Added: December 11, 2020
2020 journal article
Dermal exosomes containing miR-218-5p promote hair regeneration by regulating beta-catenin signaling
SCIENCE ADVANCES, 6(30).
co-author countries:
United States of America 🇺🇸
MeSH headings : Cells, Cultured; Exosomes; Hair; Hair Follicle; MicroRNAs / genetics; Regeneration; beta Catenin / genetics
Sources: Web Of Science, ORCID
Added: August 10, 2020
2020 review
Engineering better stem cell therapies for treating heart diseases
[Review of ]. ANNALS OF TRANSLATIONAL MEDICINE, 8(8).
author keywords: Stem cell therapy; ischemic heart diseases; bioengineering strategies; clinical translation
Sources: Web Of Science, ORCID
Added: May 26, 2020
2020 review
Exosome therapeutics for lung regenerative medicine
[Review of ]. JOURNAL OF EXTRACELLULAR VESICLES, 9(1).
co-author countries:
United States of America 🇺🇸
author keywords: Exosome; regenerative medicine; lung spheroid cell; stem cell
Sources: Web Of Science, ORCID
Added: July 20, 2020
2020 journal article
Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
NATURE COMMUNICATIONS, 11(1).
co-author countries:
United States of America 🇺🇸
MeSH headings : Administration, Inhalation; Alveolar Epithelial Cells / drug effects; Alveolar Epithelial Cells / metabolism; Alveolar Epithelial Cells / pathology; Animals; Apoptosis / drug effects; Bleomycin / toxicity; Cell Proliferation; Disease Models, Animal; Exosomes / metabolism; Exosomes / transplantation; Humans; Idiopathic Pulmonary Fibrosis / chemically induced; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Idiopathic Pulmonary Fibrosis / therapy; Lung / cytology; Lung / metabolism; Lung Injury / chemically induced; Lung Injury / metabolism; Lung Injury / pathology; Lung Injury / therapy; Mesenchymal Stem Cells / metabolism; Mice; Myofibroblasts / cytology; Proteomics; Silicon Dioxide / toxicity; Spheroids, Cellular / metabolism
Sources: Web Of Science, ORCID
Added: March 23, 2020
2020 journal article
Light-triggered NO-releasing nanoparticles for treating mice with liver fibrosis
NANO RESEARCH, 13(8), 2197–2202.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: liver fibrosis; nitric oxide (NO); hepatic stellate cells (HSC); nanoparticles; near infrared light (NIR)-controlled release
Sources: Web Of Science, ORCID
Added: June 29, 2020
2020 review
Recent Development in Therapeutic Cardiac Patches
[Review of ]. FRONTIERS IN CARDIOVASCULAR MEDICINE, 7.
co-author countries:
United States of America 🇺🇸
author keywords: biomaterials; cardiac patch; myocardial infarction; cell therapy; cardiac tissue regeneration
Source: Web Of Science
Added: January 4, 2021
2020 journal article
Targeted anti-IL-1 beta platelet microparticles for cardiac detoxing and repair
SCIENCE ADVANCES, 6(6).
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Apoptosis; Blood Platelets / metabolism; Cell-Derived Microparticles / metabolism; Cytokines / metabolism; Disease Models, Animal; Humans; Immunohistochemistry; Inflammation Mediators / metabolism; Interleukin-1beta / antagonists & inhibitors; Mice; Models, Biological; Myocardial Infarction / etiology; Myocardial Infarction / metabolism; Myocardial Infarction / pathology; Myocytes, Cardiac / metabolism; Protein Binding; Ventricular Remodeling
Sources: Web Of Science, ORCID
Added: March 2, 2020
2020 journal article
Tumor cell-derived exosomes home to their cells of origin and can be used as Trojan horses to deliver cancer drugs
THERANOSTICS, 10(8), 3474–3487.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: exosome; homing; integrin; doxorubicin; cancer therapy
MeSH headings : Animals; Antibiotics, Antineoplastic / administration & dosage; Antineoplastic Agents / administration & dosage; Cell Line, Tumor; Doxorubicin / administration & dosage; Doxorubicin / analogs & derivatives; Drug Delivery Systems; Exosomes / metabolism; HeLa Cells; Humans; Mice; Mice, Nude; Polyethylene Glycols / administration & dosage
Sources: Web Of Science, ORCID
Added: March 30, 2020
2019 journal article
Antibody-Armed Platelets for the Regenerative Targeting of Endogenous Stem Cells
NANO LETTERS, 19(3), 1883–1891.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Myocardium infarction; platelets; endogenous stem cells; antibodies
MeSH headings : Animals; Antigens, CD34 / immunology; Blood Platelets / chemistry; Blood Platelets / immunology; Cell- and Tissue-Based Therapy; Disease Models, Animal; Heart Injuries / genetics; Heart Injuries / pathology; Heart Injuries / therapy; Humans; Mice; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocardium / immunology; Myocardium / pathology; Stem Cells / immunology; Stem Cells / metabolism
Sources: Web Of Science, ORCID
Added: April 2, 2019
2019 journal article
Biomimetics: Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury (Adv. Funct. Mater. 4/2019)
Advanced Functional Materials, 29(4), 1970019.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 21, 2020
2019 journal article
Bispecific Antibody Therapy for Effective Cardiac Repair through Redirection of Endogenous Stem Cells
ADVANCED THERAPEUTICS, 2(10).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: bispecific antibodies; immunotherapy; myocardial infarction; stem cells
Sources: Web Of Science, ORCID
Added: January 27, 2020
2019 review
Cell and biomaterial-based approaches to uterus regeneration
[Review of ]. REGENERATIVE BIOMATERIALS, 6(3), 141–148.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Asherman's syndrome; intrauterine adhesions; endometrium; stem cells
Sources: Web Of Science, ORCID
Added: September 16, 2019
2019 review
Chemical Engineering of Cell Therapy for Heart Diseases
[Review of ]. ACCOUNTS OF CHEMICAL RESEARCH, 52(6), 1687–1696.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Biocompatible Materials / chemistry; Biomimetics / methods; Cardiomyopathy, Dilated / therapy; Cell- and Tissue-Based Therapy / methods; Chemical Engineering / methods; Exosomes; Humans; Hydrogels / chemistry; Myocardial Infarction / therapy; Stem Cells / chemistry; Stem Cells / metabolism
Sources: Web Of Science, ORCID
Added: July 15, 2019
2019 review
Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure
[Review of ]. CIRCULATION RESEARCH, 124(1), 161–169.
co-author countries:
China 🇨🇳 France 🇫🇷 Japan 🇯🇵 Singapore 🇸🇬 United States of America 🇺🇸
author keywords: bioengineering; heart failure; myocardium; stem cells; tissue engineering
MeSH headings : Animals; Biological Science Disciplines; Biomedical Engineering; Biomedical Research; Cooperative Behavior; Diffusion of Innovation; Heart / physiopathology; Heart Failure / metabolism; Heart Failure / pathology; Heart Failure / physiopathology; Heart Failure / therapy; Humans; Interdisciplinary Communication; Myocardium / metabolism; Myocardium / pathology; Recovery of Function; Regeneration
Source: Web Of Science
Added: February 4, 2019
2019 journal article
Hyaluronic Acid Hydrogel Integrated with Mesenchymal Stem Cell-Secretome to Treat Endometrial Injury in a Rat Model of Asherman's Syndrome
ADVANCED HEALTHCARE MATERIALS, 8(14).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Asherman's syndrome; endometrial injury; hyaluronic acid; mesenchymal stem cells; secretome
MeSH headings : Animals; Disease Models, Animal; Electrocoagulation; Endometrium / injuries; Female; Gynatresia / therapy; Human Umbilical Vein Endothelial Cells / metabolism; Humans; Hyaluronic Acid / chemistry; Hydrogels / chemistry; Mesenchymal Stem Cells / metabolism; Pregnancy; Rats, Sprague-Dawley
Sources: Web Of Science, ORCID
Added: August 12, 2019
2019 journal article
Needle-Free Injection of Exosomes Derived from Human Dermal Fibroblast Spheroids Ameliorates Skin Photoaging
ACS NANO, 13(10), 11273–11282.
co-author countries:
United States of America 🇺🇸
author keywords: needle free injection; dermal fibroblasts; spheroids; exosomes; skin aging; microRNA
MeSH headings : Animals; Biopolymers / metabolism; Cell Proliferation / radiation effects; Cells, Cultured; Enzyme-Linked Immunosorbent Assay; Exosomes / metabolism; Fibroblasts / metabolism; Humans; Mice; Mice, Nude; Skin / cytology; Skin / radiation effects; Skin Aging / radiation effects; Spheroids, Cellular / cytology; Spheroids, Cellular / radiation effects; Tissue Inhibitor of Metalloproteinase-1 / metabolism; Transforming Growth Factor beta / metabolism; Tumor Necrosis Factor-alpha / metabolism; Ultraviolet Rays; Wound Healing / radiation effects
Sources: Web Of Science, ORCID
Added: November 11, 2019
2019 journal article
Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury
ADVANCED FUNCTIONAL MATERIALS, 29(4).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: biomimetics; drug delivery; ischemic injury; platelets; stromal cell secretome
Sources: Web Of Science, ORCID
Added: February 4, 2019
2019 journal article
Porous Organic Polymer-Coated Band-Aids for Phototherapy of Bacteria-Induced Wound Infection
ACS Applied Bio Materials, 2(2), 613–618.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: wound infection; porous organic polymers; Band-Aids; white light
Source: Crossref
Added: February 21, 2020
2019 journal article
microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential
JOURNAL OF CLINICAL INVESTIGATION, 129(6), 2237–2250.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Exosomes / genetics; Exosomes / metabolism; Exosomes / pathology; Female; Heart / physiology; Heart Failure / genetics; Heart Failure / metabolism; Heart Failure / pathology; Human Umbilical Vein Endothelial Cells / metabolism; Human Umbilical Vein Endothelial Cells / pathology; Humans; Male; Mice; MicroRNAs / genetics; MicroRNAs / metabolism; Myocardium / metabolism; Myocardium / pathology; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / pathology; Neovascularization, Physiologic; Proto-Oncogene Proteins c-akt / genetics; Proto-Oncogene Proteins c-akt / metabolism; Regeneration; Signal Transduction; Stromal Cells / metabolism; Stromal Cells / pathology
Sources: Web Of Science, ORCID
Added: June 24, 2019
2018 journal article
A New Era of Cardiac Cell Therapy: Opportunities and Challenges
Advanced Healthcare Materials, 8(2), 1801011.
co-author countries:
United States of America 🇺🇸
author keywords: cardiac patches; cell therapy; exosomes; injury targeting; microRNA; myocardial infarction; synthetic stem cells
MeSH headings : Animals; Biocompatible Materials / metabolism; Cell- and Tissue-Based Therapy / methods; Endocarditis / metabolism; Endocarditis / therapy; Heart Diseases / metabolism; Heart Diseases / therapy; Humans; Induced Pluripotent Stem Cells / cytology; Induced Pluripotent Stem Cells / physiology; Myocarditis / metabolism; Myocarditis / therapy; Myocardium / cytology; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Nanomedicine / methods; Paracrine Communication; Tissue Engineering / methods
Sources: Web Of Science, ORCID, Crossref
Added: February 11, 2019
2018 review
Body builder: from synthetic cells to engineered tissues
[Review of ]. CURRENT OPINION IN CELL BIOLOGY, 54, 37–42.
co-author countries:
United States of America 🇺🇸
MeSH headings : Artificial Cells / metabolism; Humans; Models, Biological; Regenerative Medicine; Tissue Engineering / methods
Sources: Web Of Science, ORCID
Added: November 12, 2018
2018 journal article
Cardiac Stem Cell Patch Integrated with Microengineered Blood Vessels Promotes Cardiomyocyte Proliferation and Neovascularization after Acute Myocardial Infarction
ACS APPLIED MATERIALS & INTERFACES, 10(39), 33088–33096.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: microvessels; hydrodynamic focusing; cardiac stem cells; cardiomyocyte proliferation; angiogenesis; myocardial infarction
MeSH headings : Animals; Cells, Cultured; Female; Human Umbilical Vein Endothelial Cells; Humans; Microfluidic Analytical Techniques; Myocardial Infarction / therapy; Myocardium / cytology; Myocytes, Cardiac / cytology; Myocytes, Cardiac / physiology; Neovascularization, Physiologic / physiology; Rats; Rats, Nude; Stem Cells / cytology; Stem Cells / physiology
Sources: Web Of Science, ORCID
Added: October 29, 2018
2018 journal article
Cardiac cell-integrated microneedle patch for treating myocardial infarction
SCIENCE ADVANCES, 4(11).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Cells, Cultured; Microtechnology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Needles; Rats; Rats, Inbred WKY; Regeneration; Stromal Cells / cytology; Stromal Cells / transplantation; Swine; Tissue Engineering / instrumentation
Sources: Web Of Science, ORCID
Added: December 31, 2018
2018 journal article
Concise Review: Is Cardiac Cell Therapy Dead? Embarrassing Trial Outcomes and New Directions for the Future
Stem Cells Translational Medicine, 7(4), 354–359.
co-author countries:
China 🇨🇳 Japan 🇯🇵 New Zealand 🇳🇿 United States of America 🇺🇸
author keywords: Myocardial injury; Stem cell therapy; Synthetic stem cells; Biomaterials
MeSH headings : Animals; Cell- and Tissue-Based Therapy / methods; Heart / physiology; Heart Diseases / therapy; Humans; Regeneration / physiology; Stem Cell Transplantation / methods; Stem Cells / cytology
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2018 journal article
Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy
NATURE BIOMEDICAL ENGINEERING, 2(11), 831–840.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Antibodies / chemistry; Antibodies / immunology; Blood Platelets / chemistry; Blood Platelets / cytology; Blood Platelets / metabolism; Cell Line, Tumor; Chemokines / metabolism; Cytokines / metabolism; Disease Models, Animal; Female; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells / chemistry; Hematopoietic Stem Cells / cytology; Hematopoietic Stem Cells / metabolism; Leukemia / therapy; Mice; Mice, Inbred C57BL; Mice, Knockout; Programmed Cell Death 1 Receptor / deficiency; Programmed Cell Death 1 Receptor / genetics; Programmed Cell Death 1 Receptor / immunology; T-Lymphocytes / cytology; T-Lymphocytes / immunology; T-Lymphocytes / metabolism
Source: Web Of Science
Added: November 26, 2018
2018 journal article
Mesenchymal Stem Cell/Red Blood Cell-Inspired Nanoparticle Therapy in Mice with Carbon Tetrachloride-Induced Acute Liver Failure
ACS Nano, 12(7), 6536–6544.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: mesenchymal stem cells; red blood cells; biomimetic; nanoparticles; membrane cloaking; liver failure
MeSH headings : Animals; Apoptosis; Biomimetic Materials / chemistry; Biomimetic Materials / therapeutic use; Carbon Tetrachloride; Cell Line; Cell Proliferation; Disease Models, Animal; Erythrocyte Membrane / chemistry; Humans; Liver Failure, Acute / chemically induced; Liver Failure, Acute / pathology; Liver Failure, Acute / physiopathology; Liver Failure, Acute / therapy; Liver Regeneration; Male; Mesenchymal Stem Cells / chemistry; Mice; Mice, Inbred C57BL; Nanoparticles / chemistry; Nanoparticles / therapeutic use
Sources: Crossref, ORCID
Added: September 10, 2019
2018 article
Metastatic melanoma and cervical tumor cell clusters can exit blood vessels through angiopellosis augmenting tumor formation ability
Allen, T., Amu, E., Asad, D., & Cheng, K. (2018, July). CANCER RESEARCH, Vol. 78.
co-author countries:
United States of America 🇺🇸
Source: Web Of Science
Added: June 17, 2019
2018 journal article
NIPAM-based Microgel Microenvironment Regulates the Therapeutic Function of Cardiac Stromal Cells
ACS APPLIED MATERIALS & INTERFACES, 10(44), 37783–37796.
co-author countries:
Australia 🇦🇺 China 🇨🇳 United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: injectable hydrogels; NIPAM microgel; thermo-responsive microgel; cardiac stromal cells; multicellular spheroids; heart repair
MeSH headings : Acrylamides / administration & dosage; Acrylamides / chemistry; Animals; Cellular Microenvironment / drug effects; Chemokine CXCL12 / genetics; Gene Expression Regulation / drug effects; Humans; Hydrogels / administration & dosage; Hydrogels / chemistry; Hydrophobic and Hydrophilic Interactions / drug effects; Insulin-Like Growth Factor I / genetics; Mice; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / pathology; Polymers / administration & dosage; Polymers / chemistry; Rats; Stromal Cells / drug effects; Stromal Cells / pathology; Succinates / chemistry; T-Lymphocytes / drug effects; Vascular Endothelial Growth Factor A / genetics
Source: Web Of Science
Added: December 3, 2018
2018 review
Platelets and their biomimetics for regenerative medicine and cancer therapies
[Review of ]. JOURNAL OF MATERIALS CHEMISTRY B, 6(45), 7354–7365.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Antineoplastic Agents / pharmacology; Biomimetic Materials / chemistry; Biomimetic Materials / metabolism; Blood Platelets / chemistry; Blood Platelets / metabolism; Cell Line, Tumor; Cell Membrane / metabolism; Drug Carriers / chemistry; Humans; Nanoparticles / chemistry; Regenerative Medicine / methods
Sources: Web Of Science, ORCID
Added: December 10, 2018
2018 journal article
Pretargeting and Bioorthogonal Click Chemistry-Mediated Endogenous Stem Cell Homing for Heart Repair
ACS NANO, 12(12), 12193–12200.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: pretargeting; bioorthogonal click chemistry; heart repair; endogenous stem cells; engineered antibodies
MeSH headings : Animals; Antibodies / administration & dosage; Antibodies / metabolism; Blood Vessels / metabolism; Blood Vessels / pathology; Cells, Cultured; Click Chemistry; Collagen / chemistry; Collagen / metabolism; Disease Models, Animal; Endothelial Progenitor Cells / cytology; Endothelial Progenitor Cells / metabolism; Heart Diseases / metabolism; Heart Diseases / therapy; Humans; Mice; Mice, Inbred C57BL; Molecular Structure; Stem Cell Transplantation; Stem Cells / cytology; Stem Cells / metabolism
Sources: Web Of Science, ORCID
Added: January 14, 2019
2018 journal article
Targeted Treatment of Ischemic and Fibrotic Complications of Myocardial Infarction Using a Dual-Delivery Microgel Therapeutic
ACS Nano, 12(8), 7826–7837.
co-author countries:
United States of America 🇺🇸
author keywords: microgels; myocardial infarction; fibrin; fibrinolytic; fibrosis; ischemia reperfusion; drug delivery
MeSH headings : Acrylic Resins / chemical synthesis; Acrylic Resins / chemistry; Acrylic Resins / therapeutic use; Animals; Fibrosis / complications; Fibrosis / drug therapy; Fibrosis / metabolism; Ischemia / complications; Ischemia / drug therapy; Ischemia / metabolism; Myocardial Infarction / drug therapy; Myocardial Infarction / metabolism; Myocardial Infarction / pathology; Nanogels; Polyethylene Glycols / chemical synthesis; Polyethylene Glycols / chemistry; Polyethylene Glycols / therapeutic use; Polyethyleneimine / chemical synthesis; Polyethyleneimine / chemistry; Polyethyleneimine / therapeutic use; Rats
Sources: Crossref, ORCID
Added: February 21, 2020
2018 journal article
Targeted repair of heart injury by stem cells fused with platelet nanovesicles
NATURE BIOMEDICAL ENGINEERING, 2(1), 17–26.
co-author countries:
China 🇨🇳 Japan 🇯🇵 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 6, 2018
2018 journal article
Targeting regenerative exosomes to myocardial infarction using cardiac homing peptide
THERANOSTICS, 8(7), 1869–1878.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Targeting; exosomes; cardiac regeneration; heart disease; myocardial infarction
MeSH headings : Administration, Intravenous; Animals; Biological Products / administration & dosage; Biological Products / pharmacokinetics; Biological Therapy / methods; Cell Survival; Disease Models, Animal; Echocardiography; Exosomes; Molecular Targeted Therapy / methods; Myocardial Infarction / therapy; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / physiology; Peptides / administration & dosage; Peptides / pharmacokinetics; Rats; Treatment Outcome
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
A Regenerative Cardiac Patch Formed by Spray Painting of Biomaterials onto the Heart
Tissue Engineering Part C: Methods, 23(3), 146–155.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: cardiac patch; platelet fibrin gel; myocardial infarction; regeneration
MeSH headings : Animals; Biocompatible Materials / chemistry; Blood Platelets / metabolism; Fibrin / metabolism; Heart / physiology; Male; Mice; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Paintings; Rats; Rats, Sprague-Dawley; Regeneration / physiology
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Derivation of therapeutic lung spheroid cells from minimally invasive transbronchial pulmonary biopsies
Respiratory Research, 18(1).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Pulmonary progenitor cells; Lung spheroid; Stem cell
MeSH headings : Adolescent; Aged; Animals; Biopsy; Bronchi / cytology; Bronchi / physiology; Cell Culture Techniques / methods; Female; Human Umbilical Vein Endothelial Cells / physiology; Humans; Infusions, Intravenous; Lung / cytology; Lung / physiology; Male; Mice; Mice, Nude; Middle Aged; Spheroids, Cellular / physiology; Stem Cell Transplantation / methods; Stem Cells / physiology
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Fabrication of Synthetic Mesenchymal Stem Cells for the Treatment of Acute Myocardial Infarction in Mice
Circulation Research, 120(11), 1768–1775.
co-author countries:
China 🇨🇳 Japan 🇯🇵 United States of America 🇺🇸
author keywords: artificial cells; mesenchymal stem cells; myocardial infarction; regeneration; stem cells; tissue engineering
MeSH headings : Animals; Cells, Cultured; Humans; Lactic Acid / administration & dosage; Male; Mesenchymal Stem Cell Transplantation / methods; Mesenchymal Stem Cells / metabolism; Mice; Mice, Inbred C57BL; Myocardial Infarction / diagnostic imaging; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Polyglycolic Acid / administration & dosage; Polylactic Acid-Polyglycolic Acid Copolymer; Positron-Emission Tomography / methods; Treatment Outcome
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Heart Repair Using Nanogel-Encapsulated Human Cardiac Stem Cells in Mice and Pigs with Myocardial Infarction
ACS NANO, 11(10), 9738–9749.
co-author countries:
Australia 🇦🇺 China 🇨🇳 United States of America 🇺🇸
author keywords: cardiac stem cells; nanogel; myocardial infarction; biomaterials; mouse model; pig model
MeSH headings : Acrylamides / chemistry; Acrylates / chemistry; Animals; Disease Models, Animal; Female; Humans; Mice; Myocardial Infarction / metabolism; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Nanogels; Particle Size; Polyethylene Glycols / chemistry; Polyethyleneimine / chemistry; Surface Properties; Swine; Temperature
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Intracoronary allogeneic cardiosphere-derived stem cells are safe for use in dogs with dilated cardiomyopathy
Journal of Cellular and Molecular Medicine, 21(8), 1503–1512.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: cardiosphere-derived cells; dogs; dilated cardiomyopathy; stem cell therapy; allogeneic
MeSH headings : Animals; Biomarkers / metabolism; Cardiomyopathy, Dilated / diagnostic imaging; Cardiomyopathy, Dilated / immunology; Cardiomyopathy, Dilated / pathology; Cardiomyopathy, Dilated / therapy; Coronary Vessels / cytology; Coronary Vessels / immunology; Dogs; Echocardiography; Endoglin / genetics; Endoglin / immunology; Female; Gene Expression; Humans; Male; Myocardium / immunology; Myocardium / pathology; Proto-Oncogene Proteins c-kit / genetics; Proto-Oncogene Proteins c-kit / immunology; Spheroids, Cellular / cytology; Spheroids, Cellular / immunology; Spheroids, Cellular / transplantation; Stem Cell Transplantation; Stem Cells / cytology; Stem Cells / immunology; Thy-1 Antigens / genetics; Thy-1 Antigens / immunology; Transplantation, Homologous
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2017 journal article
Magnetic Targeting of Stem Cell Derivatives Enhances Hepatic Engraftment into Structurally Normal Liver
Cell Transplantation, 26(12), 1868–1877.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Cell Differentiation / physiology; Cell Proliferation / physiology; Cell Survival / physiology; Hepatocytes / cytology; Hepatocytes / physiology; Liver / cytology; Liver Regeneration / physiology; Mice; Mice, Inbred BALB C; Stem Cells / cytology; Stem Cells / physiology
Source: Crossref
Added: July 28, 2019
2017 journal article
Safety and Efficacy of Allogeneic Lung Spheroid Cells in a Mismatched Rat Model of Pulmonary Fibrosis
STEM CELLS Translational Medicine, 6(10), 1905–1916.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Fibrosis; Pulmonary; Syngeneic; Allogeneic; Stem cells
MeSH headings : Animals; Bleomycin / toxicity; Cells, Cultured; Female; Lung / cytology; Pulmonary Fibrosis / etiology; Pulmonary Fibrosis / therapy; Rats; Rats, Wistar; Spheroids, Cellular / transplantation; Stem Cell Transplantation / adverse effects; Stem Cell Transplantation / methods; Transplantation, Homologous / adverse effects; Transplantation, Homologous / methods
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome
Nature Communications, 8(1).
co-author countries:
China 🇨🇳 Japan 🇯🇵 United States of America 🇺🇸
MeSH headings : Animals; Biomimetic Materials / chemistry; Biomimetic Materials / metabolism; Biomimetic Materials / pharmacology; Cell Fractionation; Cell Membrane / chemistry; Cell Membrane / metabolism; Cell Membrane / transplantation; Cell-Derived Microparticles / chemistry; Cell-Derived Microparticles / metabolism; Cell-Derived Microparticles / transplantation; Culture Media, Conditioned / chemistry; Culture Media, Conditioned / isolation & purification; Disease Models, Animal; Gene Expression; Hepatocyte Growth Factor / genetics; Hepatocyte Growth Factor / metabolism; Humans; Injections, Intralesional; Insulin-Like Growth Factor I / genetics; Insulin-Like Growth Factor I / metabolism; Intercellular Signaling Peptides and Proteins / pharmacology; Male; Mice; Myocardial Infarction / metabolism; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocardium / metabolism; Myocardium / pathology; Paracrine Communication; Recovery of Function / drug effects; Stem Cells / cytology; Stem Cells / metabolism; Vascular Endothelial Growth Factor A / genetics; Vascular Endothelial Growth Factor A / metabolism
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Transplantation of human villous trophoblasts preserves cardiac function in mice with acute myocardial infarction
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 21(10), 2432–2440.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Human villous trophoblasts; myocardial infarction; cell therapy; paracrine effects
MeSH headings : Animals; Animals, Newborn; Cells, Cultured; Chorionic Villi / transplantation; Collagen; Drug Combinations; Heart / physiopathology; Human Umbilical Vein Endothelial Cells / physiology; Humans; Laminin; Male; Mice, Inbred C57BL; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocytes, Cardiac / physiology; Neovascularization, Physiologic; Proteoglycans; Rats; Regeneration; Transplantation, Heterologous; Trophoblasts / transplantation
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Angiopellosis as an Alternative Mechanism of Cell Extravasation
STEM CELLS, 35(1), 170–180.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Extravasation; Angiopellosis; Transmigration; Stem cell infusion; Diapedesis
MeSH headings : Animals; Blood Vessels / physiology; CD11 Antigens / metabolism; Cell Aggregation; Cell Membrane / metabolism; Cell Shape; Dogs; Extravasation of Diagnostic and Therapeutic Materials / pathology; Female; Humans; Injections; Intravital Microscopy; Male; Mesenchymal Stem Cells; Microspheres; Myocytes, Cardiac / cytology; Polymers / chemistry; Rats; Time Factors; Transendothelial and Transepithelial Migration; Zebrafish / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2016 journal article
Effects of Matrix Metalloproteinases on the Performance of Platelet Fibrin Gel Spiked With Cardiac Stem Cells in Heart Repair
STEM CELLS TRANSLATIONAL MEDICINE, 5(6), 793–803.
co-author countries:
China 🇨🇳 Japan 🇯🇵 United States of America 🇺🇸
author keywords: Cardiac stem cells; Platelet fibrin gel; Matrix metalloproteinases; Heart repair
MeSH headings : Animals; Blood Platelets / metabolism; Dipeptides / administration & dosage; Disease Models, Animal; Echocardiography; Fibrin / administration & dosage; Humans; Matrix Metalloproteinase Inhibitors / administration & dosage; Matrix Metalloproteinases / metabolism; Myocardial Infarction / enzymology; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / metabolism; Rats; Regeneration / drug effects; Stem Cell Transplantation
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Adult Lung Spheroid Cells Contain Progenitor Cells and Mediate Regeneration in Rodents With Bleomycin-Induced Pulmonary Fibrosis
STEM CELLS TRANSLATIONAL MEDICINE, 4(11), 1265–1274.
co-author countries:
United States of America 🇺🇸
author keywords: Adult lung stem cells; Mesenchymal stem cells; Pulmonary fibrosis; Spheroid cell culture
MeSH headings : Adult; Animals; Antibiotics, Antineoplastic / adverse effects; Antibiotics, Antineoplastic / pharmacology; Bleomycin / adverse effects; Bleomycin / pharmacology; Female; Heterografts; Humans; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells / metabolism; Mesenchymal Stem Cells / pathology; Mice; Mice, SCID; Pulmonary Fibrosis / chemically induced; Pulmonary Fibrosis / metabolism; Pulmonary Fibrosis / pathology; Pulmonary Fibrosis / therapy; Regeneration; Spheroids, Cellular / metabolism; Spheroids, Cellular / transplantation
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Cardiac regenerative potential of cardiosphere-derived cells from adult dog hearts
Journal of Cellular and Molecular Medicine, 19(8), 1805–1813.
co-author countries:
China 🇨🇳 Japan 🇯🇵 United States of America 🇺🇸
author keywords: cardiosphere-derived cells; dogs; dilated cardiomyopathy; stem cell therapy
MeSH headings : Aging; Animals; Apoptosis; Cell Differentiation; Cells, Cultured; Dogs; Female; Fibrosis; Heart / physiology; Heart Function Tests; Mice, SCID; Myocardium / pathology; Myocytes, Cardiac / cytology; Neovascularization, Physiologic; Paracrine Communication; Regeneration; Spheroids, Cellular / cytology
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2015 journal article
Cellular Postconditioning Allogeneic Cardiosphere-Derived Cells Reduce Infarct Size and Attenuate Microvascular Obstruction When Administered After Reperfusion in Pigs With Acute Myocardial Infarction
CIRCULATION-HEART FAILURE, 8(2), 322–332.
co-author countries:
Japan 🇯🇵 United States of America 🇺🇸
author keywords: acute myocardial infarction; animal models; coronary interventions; ischemic postconditioning
MeSH headings : Animals; Coronary Vessels; Disease Models, Animal; Heart Failure / surgery; Injections, Intra-Arterial; Ischemic Postconditioning / methods; Myocardial Infarction / complications; Myocardial Infarction / therapy; Myocardial Reperfusion; Stem Cell Transplantation / methods; Swine; Swine, Miniature; Transplantation, Homologous; Ventricular Remodeling / physiology
Source: Web Of Science
Added: August 6, 2018
2015 chapter
Cryopreservation of Neonatal Cardiomyocytes
In Methods in Molecular Biology (Vol. 1299, pp. 153–160).
co-author countries:
United States of America 🇺🇸
author keywords: Cardiomyocytes; Cryopreservation; Cardiac research
MeSH headings : Animals; Animals, Newborn; Cell Culture Techniques; Cells, Cultured; Cryopreservation / methods; Myocytes, Cardiac / cytology; Rats
Sources: Web Of Science, Crossref
Added: August 6, 2018
2015 journal article
Intravenous Cardiac Stem Cell-Derived Exosomes Ameliorate Cardiac Dysfunction in Doxorubicin Induced Dilated Cardiomyopathy
Stem Cells International, 2015, 1–8.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
Sources: Web Of Science, Crossref
Added: August 6, 2018
2015 journal article
Isolation and Cryopreservation of Neonatal Rat Cardiomyocytes
Journal of Visualized Experiments, (98).
co-author countries:
Taiwan, Province of China 🇹🇼 United States of America 🇺🇸
author keywords: Developmental Biology; Issue 98; Cryopreservation; Cardiomyocytes; Cell-based Assay; Cell Culture; Cardiac Research; In Vitro Assay
MeSH headings : Actinin / analysis; Actinin / metabolism; Animals; Animals, Newborn; Cell Culture Techniques; Cell Separation / methods; Cell Survival / physiology; Cryopreservation / methods; Cryoprotective Agents / chemistry; Dimethyl Sulfoxide / chemistry; Freezing; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Rats; Sarcomeres / chemistry; Sarcomeres / metabolism
Sources: Web Of Science, Crossref
Added: August 6, 2018
2015 journal article
Rapid and Efficient Production of Coronary Artery Ligation and Myocardial Infarction in Mice Using Surgical Clips
PLOS ONE, 10(11).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Coronary Vessels / surgery; Disease Models, Animal; Ligation; Mice; Myocardial Infarction / etiology; Myocardial Infarction / mortality; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Surgical Instruments; Suture Techniques; Vascular Surgical Procedures
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Allogeneic Cardiospheres Delivered via Percutaneous Transendocardial Injection Increase Viable Myocardium, Decrease Scar Size, and Attenuate Cardiac Dilatation in Porcine Ischemic Cardiomyopathy
PLOS ONE, 9(12).
co-author countries:
Japan 🇯🇵 United States of America 🇺🇸
MeSH headings : Administration, Cutaneous; Animals; Cardiomyopathies / complications; Cardiomyopathies / immunology; Cardiomyopathies / pathology; Cardiomyopathies / therapy; Catheters; Cicatrix / complications; Cicatrix / pathology; Dilatation; Endocardium / pathology; Female; Injections; Magnetic Resonance Imaging; Male; Myocardial Ischemia / complications; Myocardial Ischemia / immunology; Myocardial Ischemia / pathology; Myocardial Ischemia / therapy; Myocytes, Cardiac / cytology; Myocytes, Cardiac / transplantation; Regeneration; Spheroids, Cellular / cytology; Spheroids, Cellular / transplantation; Survival Analysis; Sus scrofa; Transplantation, Homologous / adverse effects
Source: Web Of Science
Added: August 6, 2018
2014 journal article
CD90/Thy-1-negative cardiosphere-derived cells exhibit augmented regenerative potency in humans and mice with myocardial infarction
Journal of the American Heart Association, 3(5), 001260.
Source: NC State University Libraries
Added: April 24, 2021
2014 journal article
Cardiosphere-derived Cells Stimulate Cardiomyocyte Proliferation via β1 Integrin Signaling
Stem Cells, 32, 2397–2406.
Source: NC State University Libraries
Added: July 28, 2019
2014 journal article
Engineered Electrical Conduction Tract Restores Conduction in Complete Heart Block
Journal of the American College of Cardiology, 64(24), 2575–2585.
co-author countries:
Italy 🇮🇹
author keywords: arrhythmias; cardiac tissue engineering; gap junctions; heart conduction system
MeSH headings : Animals; Atrioventricular Block / pathology; Atrioventricular Block / physiopathology; Atrioventricular Block / surgery; Cell Transplantation / methods; Cells, Cultured; Electromagnetic Fields; Heart Conduction System / pathology; Heart Conduction System / physiopathology; Heart Conduction System / surgery; Heart Ventricles / pathology; Immunoconjugates / pharmacology; In Vitro Techniques; Magnets; Models, Cardiovascular; Myocytes, Cardiac / pathology; Rats; Rats, Sprague-Dawley; Sarcoglycans / immunology; Sarcoglycans / pharmacology; Tissue Engineering
Source: Crossref
Added: July 21, 2019
2014 journal article
Exosomes as Critical Agents of Cardiac Regeneration Triggered by Cell Therapy
Stem Cell Reports, 2(5), 606–619.
co-author countries:
United States of America 🇺🇸
MeSH headings : Albumins / pharmacology; Aniline Compounds / pharmacology; Animals; Benzylidene Compounds / pharmacology; Cell Differentiation; Cell Proliferation; Cell- and Tissue-Based Therapy; Cells, Cultured; Disease Models, Animal; Exosomes / metabolism; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / metabolism; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Knockout; Mice, SCID; MicroRNAs / genetics; MicroRNAs / metabolism; Myocardial Infarction / therapy; Myocardial Infarction / veterinary; Myocytes, Cardiac / cytology; Myocytes, Cardiac / transplantation; Neovascularization, Physiologic; Polyesters / pharmacology; Rats; Rats, Sprague-Dawley; Regeneration
Source: Crossref
Added: July 21, 2019
2014 journal article
Human Cardiosphere-Derived Cells From Advanced Heart Failure Patients Exhibit Augmented Functional Potency in Myocardial Repair
JACC: Heart Failure, 2(1), 49–61.
co-author countries:
China 🇨🇳 Japan 🇯🇵 United States of America 🇺🇸
author keywords: cardiosphere-derived cells; heart failure; myocardial infarction; patient characteristics; stromal cell-derived factor 1
MeSH headings : Adult; Aged; Animals; Cardiomyopathies / physiopathology; Extracellular Matrix; Female; Graft Survival / physiology; Heart / physiology; Heart Failure / physiopathology; Humans; Intercellular Signaling Peptides and Proteins / metabolism; Male; Mice, SCID; Middle Aged; Myocardial Infarction / physiopathology; Myocytes, Cardiac / physiology; Neovascularization, Physiologic / physiology; Oxidative Stress / physiology; Regeneration / physiology; Stem Cell Transplantation / methods; Stem Cells / physiology; Transplantation, Autologous
Source: Crossref
Added: July 21, 2019
2014 journal article
Importance of Cell-Cell Contact in the Therapeutic Benefits of Cardiosphere-Derived Cells
STEM CELLS, 32(9), 2397–2406.
co-author countries:
China 🇨🇳
author keywords: Cardiosphere-derived cells; Cardiomyocyte; Proliferation; Paracrine factors; Cell-cell communication; beta 1 integrin
MeSH headings : Animals; Cell Communication / physiology; Cell Differentiation / physiology; Cells, Cultured; Humans; Integrin beta1 / metabolism; Male; Mice; Mice, SCID; Myocardium / cytology; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Rats
Source: Crossref
Added: August 28, 2020
2014 journal article
Intracoronary Cardiosphere-Derived Cells After Myocardial Infarction
Journal of the American College of Cardiology, 63(2), 110–122.
co-author countries:
United States of America 🇺🇸
author keywords: cardiosphere-derived cells; myocardial infarction; myocardial regeneration
MeSH headings : Aged; Biopsy; Coronary Vessels; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Heart Ventricles / pathology; Heart Ventricles / physiopathology; Humans; Injections, Intra-Arterial; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Myocardial Infarction / complications; Myocardial Infarction / physiopathology; Myocardial Infarction / surgery; Myocytes, Cardiac / cytology; Myocytes, Cardiac / transplantation; Recovery of Function; Stem Cell Transplantation / methods; Time Factors; Transplantation, Autologous; Treatment Outcome; Ventricular Dysfunction, Left / etiology; Ventricular Dysfunction, Left / physiopathology; Ventricular Dysfunction, Left / surgery; Ventricular Function, Left / physiology
Source: Crossref
Added: July 21, 2019
2014 journal article
Magnetic antibody-linked nanomatchmakers for therapeutic cell targeting
Nature Communications, 5(1).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Antibodies; Bone Marrow Cells / metabolism; Bone Marrow Transplantation / methods; Cell Movement; Ferrosoferric Oxide / therapeutic use; Iron; Leukocytes, Mononuclear / metabolism; Magnets; Myocardial Infarction / therapy; Myocytes, Cardiac / metabolism; Nanotechnology / methods; Rats; Regeneration; Stem Cells
Sources: Web Of Science, Crossref
Added: August 6, 2018
2014 journal article
Magnetic targeting of cardiosphere-derived stem cells with ferumoxytol nanoparticles for treating rats with myocardial infarction
BIOMATERIALS, 35(30), 8528–8539.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Cardiac stem cells; Magnetic targeting; Myocardial infarction; Ferumoxytol; MRI; Superparamagnetic iron oxide nanoparticles
MeSH headings : Animals; Apoptosis / drug effects; Cell Movement / drug effects; Cell Proliferation / drug effects; Cell Survival / drug effects; Female; Ferrosoferric Oxide / pharmacology; Ferrosoferric Oxide / therapeutic use; Finite Element Analysis; Heart Function Tests; Heparin / pharmacology; Humans; Inflammation / pathology; Iron Overload / pathology; Magnetic Phenomena; Male; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocardium / pathology; Nanoparticles / therapeutic use; Nanoparticles / ultrastructure; Neovascularization, Physiologic / drug effects; Protamines / pharmacology; Rats; Rats, Inbred WKY; Spheroids, Cellular / drug effects; Spheroids, Cellular / pathology
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Relative Roles of CD90 and c-Kit to the Regenerative Efficacy of Cardiosphere-Derived Cells in Humans and in a Mouse Model of Myocardial Infarction
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 3(5).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: cardiosphere-derived cells; CD90; ckit; myocardial infarction
MeSH headings : Analysis of Variance; Animals; Apoptosis / physiology; Biomarkers / analysis; Cell Differentiation / physiology; Cell Transplantation / methods; Cells, Cultured; Disease Models, Animal; Heart Function Tests; Humans; Male; Mice; Mice, SCID; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / transplantation; Prospective Studies; Proto-Oncogene Proteins c-kit / metabolism; Regeneration / physiology; Role; Sensitivity and Specificity; Thy-1 Antigens / metabolism; Treatment Outcome
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Therapeutic efficacy of cardiosphere-derived cells in a transgenic mouse model of non-ischaemic dilated cardiomyopathy
European Heart Journal, 36(12), 751–762.
co-author countries:
United States of America 🇺🇸
author keywords: Cardiomyopathy; Heart failure; Cell transplantation
MeSH headings : Animals; Apoptosis / physiology; CREB-Binding Protein / metabolism; Cardiomyopathy, Dilated / pathology; Cardiomyopathy, Dilated / physiopathology; Cardiomyopathy, Dilated / therapy; Cell Differentiation; Cell Lineage; Disease Models, Animal; Doxorubicin / pharmacology; Fibrosis; Graft Survival; Heart Failure / pathology; Heart Failure / physiopathology; Heart Failure / therapy; Injections, Intralesional; Male; Mice, Transgenic; Myocarditis / physiopathology; Myocardium / pathology; Myocytes, Cardiac / transplantation; Oxidative Stress / physiology; Protein Kinase C / metabolism; Signal Transduction; Stem Cell Transplantation / methods; Ventricular Remodeling / physiology
Source: Crossref
Added: July 21, 2019
2013 journal article
Cardiomyocyte proliferation and progenitor cell recruitment underlie therapeutic regeneration after myocardial infarction in the adult mouse heart
EMBO Molecular Medicine, 5(2), 191–209.
author keywords: cardiac regeneration; cardiomyogenesis; cell therapy; fate mapping; myocardial infarction
MeSH headings : Animals; Cell Proliferation; Cell- and Tissue-Based Therapy; Cells, Cultured; Female; Humans; Male; Mice; Mice, 129 Strain; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Myocytes, Cardiac / transplantation; Regeneration; Stem Cells / cytology
Source: Crossref
Added: July 21, 2019
2013 journal article
INTRACORONARY CARDIOSPHERE-DERIVED CELLS AFTER MYOCARDIAL INFARCTION: MAGNETIC RESONANCE IMAGING ANALYSIS OF REGENERATION AND DETERMINANTS OF EFFICACY IN THE FINAL 1-YEAR RESULTS OF THE CADUCEUS TRIAL
Journal of the American College of Cardiology, 61(10), E104.
co-author countries:
United States of America 🇺🇸
Source: Crossref
Added: January 21, 2021
2013 journal article
Validation of Contrast-Enhanced Magnetic Resonance Imaging to Monitor Regenerative Efficacy After Cell Therapy in a Porcine Model of Convalescent Myocardial Infarction
Circulation, 128(25), 2764–2775.
co-author countries:
United States of America 🇺🇸
author keywords: adult stem cells; allogeneic transplantation; cell transplantation; magnetic resonance imaging; myocardial infarction; regeneration
MeSH headings : Animals; Cell- and Tissue-Based Therapy; Cicatrix / pathology; Disease Models, Animal; Gadolinium; Heart / physiopathology; Immune System / physiopathology; Magnetic Resonance Imaging / methods; Male; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocardium / pathology; Regeneration / physiology; Swine; Swine, Miniature; Time Factors; Treatment Outcome
Source: Crossref
Added: July 21, 2019
2012 journal article
Brief Report: Mechanism of Extravasation of Infused Stem Cells
STEM CELLS, 30(12), 2835–2842.
co-author countries:
China 🇨🇳
author keywords: Cell migration; Extravasation; Vasculature; Cell adhesion molecules; Metalloproteinases
MeSH headings : Animals; Cell Movement / physiology; Endothelium, Vascular / cytology; Endothelium, Vascular / metabolism; Female; Humans; Integrins / metabolism; MCF-7 Cells; Matrix Metalloproteinases / metabolism; Myocardium / cytology; Myocardium / metabolism; Peripheral Blood Stem Cell Transplantation / methods; Rats; Rats, Inbred WKY; Spheroids, Cellular; Stem Cells / cytology; Stem Cells / metabolism; Transplantation, Autologous
Source: Crossref
Added: July 21, 2019
2012 journal article
Direct Comparison of Different Stem Cell Types and Subpopulations Reveals Superior Paracrine Potency and Myocardial Repair Efficacy With Cardiosphere-Derived Cells
Journal of the American College of Cardiology, 59(10), 942–953.
co-author countries:
Greece 🇬🇷 Japan 🇯🇵 United States of America 🇺🇸
author keywords: cardiac stem cells; mesenchymal stem cells; myocardial regeneration; paracrine effects
MeSH headings : Albumins / pharmacology; Animals; Apoptosis; Bone Marrow Cells / cytology; Cell Differentiation; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; In Situ Nick-End Labeling; Male; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / metabolism; Mice; Mice, SCID; Myocardial Infarction / metabolism; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocardium / cytology; Myocytes, Cardiac / cytology; Myocytes, Cardiac / transplantation; Paracrine Communication / physiology; Polyesters / pharmacology; Rats; Rats, Inbred WKY; Stem Cell Transplantation; Wound Healing
Source: Crossref
Added: July 21, 2019
2012 journal article
Dose-dependent functional benefit of human cardiosphere transplantation in mice with acute myocardial infarction
Journal of Cellular and Molecular Medicine, 16(9), 2112–2116.
co-author countries:
China 🇨🇳
author keywords: cell transplantation; stem cells; cardiospheres; myocardial infarction; dose effects
MeSH headings : Acute Disease; Animals; Humans; Male; Mice; Mice, SCID; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocardium / metabolism; Myocardium / pathology; Myocytes, Cardiac / cytology; Myocytes, Cardiac / pathology; Myocytes, Cardiac / transplantation; Neovascularization, Physiologic; Spheroids, Cellular; Stem Cell Transplantation / methods; Stem Cells / cytology; Stem Cells / metabolism; Ventricular Remodeling
Source: Crossref
Added: July 28, 2019
2012 journal article
Functional performance of human cardiosphere-derived cells delivered in an in situ polymerizable hyaluronan-gelatin hydrogel
Biomaterials, 33(21), 5317–5324.
co-author countries:
China 🇨🇳 Japan 🇯🇵 United States of America 🇺🇸
author keywords: Acute myocardial infarction; Biodegradable polymers; Hyaluronan; Cardiac stem cells
MeSH headings : Animals; Apoptosis / drug effects; Cell Differentiation / drug effects; Cell Movement / drug effects; Cell Survival / drug effects; Gelatin / pharmacology; Humans; Hyaluronic Acid / pharmacology; Hydrogel, Polyethylene Glycol Dimethacrylate / pharmacology; Male; Mice; Microscopy, Fluorescence; Myocardium / cytology; Neovascularization, Physiologic / drug effects; Polymerization / drug effects; Spheroids, Cellular / cytology; Spheroids, Cellular / drug effects; Spheroids, Cellular / transplantation; Tissue Preservation
Source: Crossref
Added: July 28, 2019
2012 journal article
Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial
The Lancet, 379(9819), 895–904.
co-author countries:
United States of America 🇺🇸
MeSH headings : Cicatrix / etiology; Cicatrix / pathology; Coronary Vessels; Female; Heart / physiopathology; Humans; Infusions, Intra-Arterial; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocardium / cytology; Myocardium / pathology; Regeneration; Stem Cell Transplantation; Stroke Volume; Transplantation, Autologous; Ventricular Dysfunction, Left / etiology; Ventricular Dysfunction, Left / therapy
Source: Crossref
Added: July 28, 2019
2012 journal article
Intramyocardial Injection of Platelet Gel Promotes Endogenous Repair and Augments Cardiac Function in Rats With Myocardial Infarction
Journal of the American College of Cardiology, 59(3), 256–264.
co-author countries:
China 🇨🇳
author keywords: biomaterials; endogenous recruitment; myocardial infarction
MeSH headings : Animals; Blood Platelets; Female; Gels; Heart Function Tests / methods; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocardium / pathology; Random Allocation; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Regeneration / physiology
Source: Crossref
Added: July 28, 2019
2012 journal article
Safety and Efficacy of Allogeneic Cell Therapy in Infarcted Rats Transplanted With Mismatched Cardiosphere-Derived Cells
Circulation, 125(1), 100–112.
co-author countries:
United States of America 🇺🇸
author keywords: allogeneic transplantation; paracrine communication; regeneration; stem cells
MeSH headings : Animals; Cell Survival / physiology; Cells, Cultured; Female; Graft Survival / genetics; Graft Survival / physiology; Humans; Male; Myocardial Infarction / pathology; Myocardial Infarction / surgery; Myocytes, Cardiac / pathology; Myocytes, Cardiac / physiology; Myocytes, Cardiac / transplantation; Rats; Rats, Inbred BN; Rats, Inbred WKY; Spheroids, Cellular / pathology; Spheroids, Cellular / physiology; Spheroids, Cellular / transplantation; Transplantation, Homologous; Treatment Outcome
Source: Crossref
Added: July 28, 2019
2012 journal article
Three Dimensional Neuronal Cell Cultures More Accurately Model Voltage Gated Calcium Channel Functionality in Freshly Dissected Nerve Tissue
PLoS ONE, 7(9), e45074.
co-author countries:
Georgia 🇬🇪
Ed(s): G. Cymbalyuk
MeSH headings : Animals; Calcium / metabolism; Calcium Channels / metabolism; Caveolae / physiology; Caveolin 1 / genetics; Caveolin 1 / metabolism; Cell Culture Techniques; Coated Materials, Biocompatible / chemistry; DNA-Directed RNA Polymerases / genetics; DNA-Directed RNA Polymerases / metabolism; Gene Expression; Ion Channel Gating / physiology; Lactic Acid / chemistry; Mice; Molecular Imaging; Polyesters; Polymers / chemistry; Polystyrenes / chemistry; Superior Cervical Ganglion / cytology; Superior Cervical Ganglion / metabolism; Tissue Scaffolds
Source: Crossref
Added: July 21, 2019
2012 journal article
Transplantation of platelet gel spiked with cardiosphere-derived cells boosts structural and functional benefits relative to gel transplantation alone in rats with myocardial infarction
Biomaterials, 33(10), 2872–2879.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Cardiac stem cells; Platelet gel; Myocardial infarction; Cardiac regeneration
MeSH headings : Animals; Blood Platelets / cytology; Blood Platelets / ultrastructure; Cell Shape; Cells, Cultured; Endothelial Cells / cytology; Gels / pharmacology; Heart Function Tests; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocardium / pathology; Myocytes, Cardiac / cytology; Myocytes, Cardiac / transplantation; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Regeneration; Stem Cell Transplantation
Source: Crossref
Added: July 28, 2019
2011 journal article
Neural Cell 3D Microtissue Formation Is Marked by Cytokines' Up-Regulation
PLoS ONE, 6(10), e26821.
co-author countries:
Georgia 🇬🇪
Ed(s): M. Wanunu
MeSH headings : Biomarkers; Cytokines / biosynthesis; Humans; Neural Stem Cells / cytology; Primary Cell Culture / methods; Tissue Engineering / methods; Up-Regulation
Source: Crossref
Added: July 28, 2019
2011 journal article
The CADUCEUS (CArdiosphere-Derived aUtologous Stem CElls to Reverse ventricUlar dySfunction) Trial
Circulation, 124, 2365–2374.
Source: NC State University Libraries
Added: April 24, 2021
2011 journal article
The amelioration of cardiac dysfunction after myocardial infarction by the injection of keratin biomaterials derived from human hair
Biomaterials, 32(35), 9290–9299.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Heart; Keratin; Scaffold; Angiogenesis; Cardiac tissue engineering
MeSH headings : Animals; Biocompatible Materials / administration & dosage; Biocompatible Materials / pharmacology; Blotting, Western; Disease Models, Animal; Female; Hair / chemistry; Heart / drug effects; Heart / physiopathology; Heart Function Tests / drug effects; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate / pharmacology; Inflammation / complications; Inflammation / pathology; Injections; Keratins / administration & dosage; Keratins / pharmacology; Mechanical Phenomena / drug effects; Myocardial Infarction / complications; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Myocardium / metabolism; Myocardium / pathology; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / pathology; Neovascularization, Pathologic / complications; Neovascularization, Pathologic / pathology; Paracrine Communication / drug effects; Rats; Rats, Sprague-Dawley; Tissue Scaffolds / chemistry; Ventricular Remodeling / drug effects
Source: Crossref
Added: July 28, 2019
2010 journal article
Cardiospheres Recapitulate a Niche-Like Microenvironment Rich in Stemness and Cell-Matrix Interactions, Rationalizing Their Enhanced Functional Potency for Myocardial Repair
STEM CELLS, 28(11), 2088–2098.
author keywords: Cardiac stem cells; Stem cell niche; Extracellular-matrix molecules; Adhesion molecule
MeSH headings : Animals; Blotting, Western; Cells, Cultured; Echocardiography; Extracellular Matrix / metabolism; Flow Cytometry; Histone Deacetylase 2 / metabolism; Humans; Insulin-Like Growth Factor I / metabolism; Integrin alpha2 / metabolism; Laminin / metabolism; Mice; Mice, SCID; Myocardial Infarction / metabolism; Myocardial Infarction / therapy; Myocardium / cytology; Myocardium / metabolism; Oxidative Stress / physiology; Polymerase Chain Reaction; Stem Cell Transplantation; Stem Cells / cytology; Stem Cells / metabolism; Telomerase / metabolism
Source: Crossref
Added: July 28, 2019
2010 journal article
Dedifferentiation and Proliferation of Mammalian Cardiomyocytes
PLoS ONE, 5(9), e12559.
co-author countries:
United States of America 🇺🇸
Ed(s): A. Kowaltowski
MeSH headings : Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; GATA4 Transcription Factor / genetics; GATA4 Transcription Factor / metabolism; Homeobox Protein Nkx-2.5; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Male; Mice; Mice, Transgenic; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Rats; Rats, Inbred WKY; Transcription Factors / genetics; Transcription Factors / metabolism
Source: Crossref
Added: July 28, 2019
2010 journal article
Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair
Cardiovascular Research, 89(1), 157–165.
co-author countries:
United States of America 🇺🇸
author keywords: Physiological oxygen; Ex vivo expansion; Cardiac stem cells
MeSH headings : Adult; Adult Stem Cells / cytology; Adult Stem Cells / physiology; Adult Stem Cells / transplantation; Aneuploidy; Animals; Cell Differentiation; Cell Proliferation; Cellular Senescence; DNA Damage; Humans; In Vitro Techniques; Male; Mice; Mice, SCID; Muscle Development / physiology; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocardium / cytology; Oxidative Stress; Oxygen / physiology; Reactive Oxygen Species / metabolism; Regeneration / physiology; Transplantation, Heterologous
Source: Crossref
Added: July 28, 2019
2010 journal article
Exploring cellular adhesion and differentiation in a micro-/nano-hybrid polymer scaffold
Biotechnology Progress, 26(3), 838–846.
co-author countries:
United States of America 🇺🇸
author keywords: tissue engineering; scaffold; stem cell; micro-/nano-fabrication; adhesion
MeSH headings : Cell Adhesion; Cell Differentiation; Cells, Cultured; Fibroblasts / cytology; Humans; Materials Testing; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Nanostructures / chemistry; Nanostructures / ultrastructure; Neurons / cytology; Porosity; Shear Strength; Stem Cells / cytology; Tissue Engineering / methods; Tissue Scaffolds / chemistry
Source: Crossref
Added: July 28, 2019
2010 journal article
Heart to Heart
Circulation, 121(18), 1981–1984.
author keywords: Editorials; heart; regenerative medicine; stem cells
MeSH headings : Bone Marrow Cells / cytology; Hematopoietic Stem Cell Transplantation; Humans; Myocardial Ischemia / therapy; Myocytes, Cardiac / cytology; Regeneration
Source: Crossref
Added: July 28, 2019
2010 journal article
Magnetic Targeting Enhances Engraftment and Functional Benefit of Iron-Labeled Cardiosphere-Derived Cells in Myocardial Infarction
Circulation Research, 106(10), 1570–1581.
co-author countries:
United States of America 🇺🇸
author keywords: cardiac progenitor cells; cell transplantation; myocardial infarction; targeted cell delivery
MeSH headings : Animals; Cell Differentiation; Cell Survival; Echocardiography; Female; Genes, sry; In Situ Nick-End Labeling; Inflammation / physiopathology; Iron; Male; Mesenchymal Stem Cell Transplantation / methods; Myocardial Infarction / diagnostic imaging; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Myocardial Infarction / surgery; Polymerase Chain Reaction; Rats; Rats, Inbred WKY
Source: Crossref
Added: July 28, 2019
2009 journal article
Validation of the Cardiosphere Method to Culture Cardiac Progenitor Cells from Myocardial Tissue
PLoS ONE, 4(9), e7195.
co-author countries:
United States of America 🇺🇸
Ed(s): A. Leri
MeSH headings : Adult; Animals; Cell Culture Techniques / methods; Cell Lineage; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, SCID; Mice, Transgenic; Middle Aged; Myocardium / metabolism; Myocardium / pathology; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Rats; Rats, Inbred WKY; Stem Cells / cytology
Source: Crossref
Added: July 28, 2019
2008 journal article
ENStem-A human neural progenitors cultured in 3D polystyrene scaffolds for high physiological relevance
Cellutions, 3, 4–6.
Source: NC State University Libraries
Added: April 24, 2021
2008 journal article
Taking Cell Culture in Drug Discovery to the Third Dimension - A Patent Review
Recent Patents on Biomedical Engineeringe, 1(2), 103–115.
co-author countries:
United States of America 🇺🇸
Source: Crossref
Added: July 28, 2019
2008 journal article
Three-dimensional polymer scaffolds for high throughput cell-based assay systems
Biomaterials, 29(18), 2802–2812.
co-author countries:
United States of America 🇺🇸
author keywords: biomimetic material; ECM; cell culture; scaffold; stem cell
MeSH headings : Biocompatible Materials / chemistry; Biological Assay / methods; Blotting, Western; Cell Culture Techniques / instrumentation; Cell Culture Techniques / methods; Cell Line; Humans; Microscopy, Electron, Scanning; Neurons / cytology; Neurons / metabolism; Neurons / ultrastructure; Oligonucleotide Array Sequence Analysis; Polymers / chemistry; Porosity; Stem Cells / cytology; Stem Cells / metabolism; Stem Cells / ultrastructure; Tissue Scaffolds
Source: Crossref
Added: July 28, 2019
2003 journal article
Application potentials of on-line near infrared spectroscopy technology in manufacturing of traditional chinese medicine
China Journal of Chinese Materia Medica, 28, 1117–1119.
Source: NC State University Libraries
Added: April 24, 2021
