Kari D. Loomis

Works (1)

Updated: July 5th, 2023 15:54

2007 article

Genetic Ablation of CCAAT/Enhancer Binding Protein α in Epidermis Reveals Its Role in Suppression of Epithelial Tumorigenesis

Loomis, K. D., Zhu, S., Yoon, K., Johnson, P. F., & Smart, R. C. (2007, July 15). Cancer Research, Vol. 67, pp. 6768–6776.

By: K. Loomis n, S. Zhu*, K. Yoon*, P. Johnson * & R. Smart n 

MeSH headings : Animals; Apoptosis; CCAAT-Enhancer-Binding Protein-alpha / genetics; Cell Differentiation; Cell Proliferation; Epidermis / metabolism; Epithelial Cells / metabolism; Gene Expression Regulation, Neoplastic; Keratinocytes / cytology; Mice; Mice, Inbred BALB C; Mice, Knockout; Mutation; NIH 3T3 Cells; ras Proteins / metabolism
topics (OpenAlex): Genomics and Chromatin Dynamics; Retinoids in leukemia and cellular processes; Cancer-related Molecular Pathways
TL;DR: C/EBPalpha is dispensable for epidermal homeostasis and provides genetic evidence that C/EB Palpha is a suppressor of epithelial tumorigenesis, as well as proposed to block cell cycle progression through inhibition of E2F activity. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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