Katherine Ellen Simon

College of Veterinary Medicine

Works (4)

Updated: December 13th, 2024 05:01

2024 journal article

A randomized, controlled clinical trial demonstrates improved owner-assessed cognitive function in senior dogs receiving a senolytic and NAD plus precursor combination

SCIENTIFIC REPORTS, 14(1).

By: K. Simon n, K. Russell n, A. Mondino  n, C. Yang n, B. Case n, Z. Anderson n, C. Whitley n, E. Griffith n , M. Gruen n , N. Olby n 

author keywords: Aging; Senolytic; NAD plus; Canine cognitive dysfunction syndrome; Cognitive impairment; Longevity
topics (OpenAlex): Human-Animal Interaction Studies; Gut microbiota and health; Dementia and Cognitive Impairment Research
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Sources: Web Of Science, NC State University Libraries
Added: June 24, 2024

2024 journal article

Cross-sectional and longitudinal analysis of health-related quality of life (HRQoL) in senior and geriatric dogs

PLOS ONE, 19(9).

By: A. Mondino  n, C. Yang n, K. Simon n, G. Fefer n, J. Robertson n , M. Gruen n , N. Olby n 

Ed(s): J. Suchodolski

topics (OpenAlex): Human-Animal Interaction Studies; Veterinary Orthopedics and Neurology; Veterinary Oncology Research
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3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 8, 2024

2023 journal article

Development and validation of a sleep questionnaire, SNoRE 3.0, to evaluate sleep in companion dogs

SCIENTIFIC REPORTS, 13(1).

By: A. Mondino  n, C. Ludwig n, C. Menchaca n, K. Russell n, K. Simon n, E. Griffith n , A. Kis *, B. Lascelles  n, M. Gruen n , N. Olby n 

topics (OpenAlex): Human-Animal Interaction Studies; Neuroscience of respiration and sleep; Infant Health and Development
TL;DR: A valid and reliable questionnaire tool is described, that can be used as a cost-effective way to monitor dog sleep in clinical settings. (via Semantic Scholar)
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8. Decent Work and Economic Growth (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 23, 2023

2022 journal article

Cross-species evolution of a highly potent AAV variant for therapeutic gene transfer and genome editing

NATURE COMMUNICATIONS, 13(1).

By: T. Gonzalez *, K. Simon*, L. Blondel *, M. Fanous*, A. Roger *, M. Maysonet, G. Devlin*, T. Smith * ...

MeSH headings : Animals; Dependovirus / metabolism; Gene Editing; Genetic Therapy; Genetic Vectors / genetics; Humans; Macaca / genetics; Mice; Swine; Transduction, Genetic
topics (OpenAlex): CRISPR and Genetic Engineering; Virus-based gene therapy research; Neurogenetic and Muscular Disorders Research
TL;DR: A highly potent new variant of AAV, AAV.cc47, is described with enhanced transduction efficiency over AAV serotype 9 and its efficacy is shown in different mouse models, pigs and non-human primates. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: October 17, 2022

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