Works (44)

Updated: May 24th, 2023 05:03

2023 journal article

An inhaled bioadhesive hydrogel to shield non-human primates from SARS-CoV-2 infection

Nature Materials, 2.

By: X. Mei, J. Li, Z. Wang, D. Zhu, K. Huang, S. Hu, K. Popowski, K. Cheng

Sources: Web Of Science, ORCID, Crossref
Added: March 6, 2023

2023 journal article

Intrapericardial long non-coding RNA–Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair

European Heart Journal, 44(19), 1748–1760.

By: D. Zhu, S. Liu, K. Huang, J. Li, X. Mei, Z. Li, K. Cheng

author keywords: Myocardial infarction; Adverse remodelling; Mesenchymal stem cell; EVs; lncRNA; Tcf21
Sources: Web Of Science, Crossref, ORCID
Added: April 4, 2023

2022 journal article

Inhalable dry powder mRNA vaccines based on extracellular vesicles

Matter, 5(9), 2960–2974.

By: K. Popowski, A. Moatti, G. Scull, D. Silkstone, H. Lutz, B. López de Juan Abad n, A. George, E. Belcher n ...

Sources: Web Of Science, Crossref, ORCID
Added: October 17, 2022

2022 journal article

Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3

CIRCULATION RESEARCH, 131(10), E135–E150.

By: D. Zhu, S. Liu, K. Huang, Z. Wang, S. Hu, J. Li, Z. Li, K. Cheng

author keywords: exosomes; immunomodulation; mesesnchymal stem cell; myocardial infarction; regulatory T cell
Sources: Web Of Science, ORCID
Added: November 14, 2022

2022 journal article

Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem cells in myocardial infarction

CHEMICAL ENGINEERING JOURNAL, 427.

By: J. Li, Y. Lv*, D. Zhu, X. Mei, K. Huang, X. Wang n, Z. Li, S. Zhang ...

author keywords: Mesenchymal stem cells; Hydrogel; Myocardial infarction; Intrapericardial; Intramyocardial
Sources: Web Of Science, ORCID
Added: January 3, 2022

2022 journal article

Minimally invasive delivery of a hydrogel-based exosome patch to prevent heart failure

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 169, 113–121.

By: G. Cheng, D. Zhu, K. Huang & T. Caranasos*

Sources: Web Of Science, ORCID
Added: October 31, 2022

2022 journal article

Sealing the heart from the inside out

Nature Biomedical Engineering, 7(2), 87–88.

By: K. Huang & K. Cheng

Sources: Web Of Science, ORCID, Crossref
Added: February 6, 2023

2022 article

Skin-Interfaced Deep-Tissue Sensing Patch via Microneedle Waveguides

Liu, Y., Menon, R., Putcha, A., Huang, K., Bonilla, L., Vora, R., … Bai, W. (2022, June 29). ADVANCED MATERIALS TECHNOLOGIES, Vol. 6.

By: Y. Liu*, R. Menon*, A. Putcha n, K. Huang, L. Bonilla n, R. Vora n, J. Li n, L. Zhang* ...

author keywords: biosensors; microneedles; optoelectronics; waveguides; wearable devices
Sources: Web Of Science, ORCID
Added: July 5, 2022

2022 journal article

Skin‐Interfaced Deep‐Tissue Sensing Patch via Microneedle Waveguides (Adv. Mater. Technol. 9/2022)

Advanced Materials Technologies, 7(9), 2270058.

By: Y. Liu*, R. Menon*, A. Putcha n, K. Huang, L. Bonilla n, R. Vora n, J. Li n, L. Zhang* ...

Sources: Crossref, ORCID
Added: May 23, 2023

2021 journal article

3D Bioprinting Technology – One Step Closer Towards Cardiac Tissue Regeneration

Frontiers in Materials, 8.

By: M. Chingale, K. Cheng & K. Huang

author keywords: 3D bioprinting; scaffolds-based 3D bioprinting; 3D cardiac patch; cardiac regeneration; cardiac repair
Sources: Web Of Science, Crossref, ORCID
Added: March 7, 2022

2021 journal article

A Minimally Invasive Exosome Spray Repairs Heart after Myocardial Infarction

ACS NANO, 15(7), 11099–11111.

By: J. Yao*, K. Huang, D. Zhu, T. Chen*, Y. Jiang*, J. Zhang*, L. Mi*, H. Xuan* ...

author keywords: MSC; exosome; spray; myocardial infarction; heart repair
Sources: Web Of Science, ORCID
Added: August 23, 2021

2021 journal article

A fluid-powered refillable origami heart pouch for minimally invasive delivery of cell therapies in rats and pigs

MED, 2(11), 1253-+.

By: X. Mei, D. Zhu, J. Li, K. Huang, S. Hu, Z. Li, B. Abad n, K. Cheng

Sources: Web Of Science, ORCID
Added: November 3, 2021

2021 journal article

A stem cell-derived ovarian regenerative patch restores ovarian function and rescues fertility in rats with primary ovarian insufficiency

THERANOSTICS, 11(18), 8894–8908.

By: S. Zhang, D. Zhu, Z. Li, K. Huang, S. Hu, H. Lutz, M. Xie, X. Mei ...

author keywords: primary ovarian insufficiency; ovarian regenerative patch; regenerative medicine; mesenchymal stem cells; acellular therapy; fertility
Sources: Web Of Science, ORCID
Added: October 12, 2021

2021 review

All Roads Lead to Rome (the Heart): Cell Retention and Outcomes From Various Delivery Routes of Cell Therapy Products to the Heart

[Review of ]. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(8).

By: J. Li, S. Hu, D. Zhu, K. Huang, X. Mei, B. Abad n, K. Cheng

author keywords: cardiac repair; cell delivery; intracoronary; intramyocardial; intrapericardial; intravenous; retention rate
Sources: Web Of Science, ORCID
Added: June 10, 2021

2021 journal article

Bioengineering Technologies for Cardiac Regenerative Medicine

Frontiers in Bioengineering and Biotechnology, 9.

By: M. Chingale, D. Zhu, K. Cheng & K. Huang

author keywords: bioengineering; cardiac repair; cell reprogramming; exosome; cardiac patch; targeting
Sources: Web Of Science, Crossref, ORCID
Added: June 28, 2021

2021 journal article

Cardiac Repair: Bispecific Antibody Inhalation Therapy for Redirecting Stem Cells from the Lungs to Repair Heart Injury (Adv. Sci. 1/2021)

Advanced Science, 8(1), 2170005.

By: M. Liu, H. Lutz, D. Zhu, K. Huang, Z. Li, P. Dinh, J. Gao, Y. Zhang, K. Cheng

Sources: Crossref, ORCID
Added: May 23, 2023

2021 journal article

Exosome-eluting stents for vascular healing after ischaemic injury

NATURE BIOMEDICAL ENGINEERING, 5(10), 1174–1188.

By: S. Hu, Z. Li, D. Shen, D. Zhu, K. Huang, T. Su, P. Dinh, J. Cores, K. Cheng

Sources: Web Of Science, ORCID
Added: April 6, 2021

2021 journal article

Extruded Mesenchymal Stem Cell Nanovesicles Are Equally Potent to Natural Extracellular Vesicles in Cardiac Repair

ACS APPLIED MATERIALS & INTERFACES, 13(47), 55767–55779.

By: X. Wang*, S. Hu, J. Li, D. Zhu, Z. Wang, J. Cores, K. Cheng, G. Liu*, K. Huang

author keywords: extrusion; nanovesicles; extracellular vesicles; mesenchymal stem cell; ischemia reperfusion injury
Sources: Web Of Science, ORCID
Added: February 21, 2022

2021 journal article

Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair

NATURE COMMUNICATIONS, 12(1).

By: D. Zhu, Z. Li, K. Huang, T. Caranasos*, J. Rossi* & K. Cheng

Sources: Web Of Science, ORCID
Added: March 6, 2021

2021 journal article

Publisher Correction: Exosome-eluting stents for vascular healing after ischaemic injury

Nature Biomedical Engineering, 5(10), 1239.

By: S. Hu n, Z. Li n, D. Shen n, D. Zhu, K. Huang, T. Su n, P. Dinh n, J. Cores n, K. Cheng n

Source: ORCID
Added: April 21, 2021

2021 journal article

Resuscitating the Field of Cardiac Regeneration: Seeking Answers from Basic Biology

Advanced Biology, 6(2), 2101133.

By: Y. Hsu n, K. Huang & K. Cheng

author keywords: cardiac hypertrophy; cardiomyogenesis; heart failure; regeneration
Sources: ORCID, Web Of Science, Crossref
Added: January 3, 2022

2020 journal article

An off-the-shelf artificial cardiac patch improves cardiac repair after myocardial infarction in rats and pigs

Science Translational Medicine, 12(538).

By: K. Huang, E. Ozpinar, T. Su n, J. Tang, D. Shen n, L. Qiao n, S. Hu n, Z. Li n ...

Source: ORCID
Added: April 9, 2020

2020 journal article

Cardiac Stromal Cell Patch Integrated with Engineered Microvessels Improves Recovery from Myocardial Infarction in Rats and Pigs

ACS BIOMATERIALS SCIENCE & ENGINEERING, 6(11), 6309–6320.

By: T. Su, K. Huang, K. Mathews, V. Scharf, S. Hu, Z. Li, B. Frame*, J. Cores ...

author keywords: microfluidics; cardiac patch; cardiac stromal cells; myocardial infarction; porcine model
Sources: Web Of Science, ORCID
Added: December 11, 2020

2020 journal article

Dermal exosomes containing miR-218-5p promote hair regeneration by regulating beta-catenin signaling

SCIENCE ADVANCES, 6(30).

By: S. Hu, Z. Li, H. Lutz, K. Huang, T. Su, J. Cores, P. Dinh, K. Cheng

Sources: Web Of Science, ORCID
Added: August 10, 2020

2020 journal article

Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

NATURE COMMUNICATIONS, 11(1).

By: P. Dinh, D. Paudel n, H. Brochu, K. Popowski, M. Gracieux n, J. Cores, K. Huang, M. Hensley n ...

Sources: Web Of Science, ORCID
Added: March 23, 2020

2020 journal article

Targeted anti-IL-1 beta platelet microparticles for cardiac detoxing and repair

SCIENCE ADVANCES, 6(6).

By: Z. Li, S. Hu, K. Huang, T. Su, J. Cores & K. Cheng

Sources: Web Of Science, ORCID
Added: March 2, 2020

2020 journal article

Tumor cell-derived exosomes home to their cells of origin and can be used as Trojan horses to deliver cancer drugs

THERANOSTICS, 10(8), 3474–3487.

By: L. Qiao n, S. Hu, K. Huang, T. Su, Z. Li, A. Vandergriff, J. Cores, P. Dinh ...

author keywords: exosome; homing; integrin; doxorubicin; cancer therapy
Sources: Web Of Science, ORCID
Added: March 30, 2020

2019 journal article

Antibody-Armed Platelets for the Regenerative Targeting of Endogenous Stem Cells

NANO LETTERS, 19(3), 1883–1891.

By: D. Shen, Z. Li, S. Hu, K. Huang, T. Su, H. Liang, F. Liu n, K. Cheng

author keywords: Myocardium infarction; platelets; endogenous stem cells; antibodies
Sources: Web Of Science, ORCID
Added: April 2, 2019

2019 journal article

Bispecific Antibody Therapy for Effective Cardiac Repair through Redirection of Endogenous Stem Cells

ADVANCED THERAPEUTICS, 2(10).

By: K. Huang, Z. Li, T. Su, D. Shen, S. Hu & K. Cheng

author keywords: bispecific antibodies; immunotherapy; myocardial infarction; stem cells
Sources: Web Of Science, ORCID
Added: January 27, 2020

2019 journal article

Hyaluronic Acid Hydrogel Integrated with Mesenchymal Stem Cell-Secretome to Treat Endometrial Injury in a Rat Model of Asherman's Syndrome

ADVANCED HEALTHCARE MATERIALS, 8(14).

By: F. Liu*, S. Hu, H. Yang n, Z. Li, K. Huang, T. Su, S. Wang*, K. Cheng

author keywords: Asherman's syndrome; endometrial injury; hyaluronic acid; mesenchymal stem cells; secretome
Sources: Web Of Science, ORCID
Added: August 12, 2019

2019 chapter

Inhalation of Lung Spheroid Cell-Secretome and Exosomes Promotes Therapeutic Lung Repair in Rodent Models of Pulmonary Fibrosis

In A29 Emerging Concepts in Lung Fibrosis (Vol. 199, pp. 1225–1225).

By: P. Dinh n, D. Paudel n, H. Brochu n, J. Cores n, K. Huang, M. Hensley n, E. Harrell n, A. Vandergriff n ...

Event: American Thoracic Society International Conference

Sources: NC State University Libraries, ORCID
Added: May 23, 2023

2019 journal article

Needle-Free Injection of Exosomes Derived from Human Dermal Fibroblast Spheroids Ameliorates Skin Photoaging

ACS NANO, 13(10), 11273–11282.

By: S. Hu, Z. Li, J. Cores, K. Huang, T. Su, P. Dinh, K. Cheng

author keywords: needle free injection; dermal fibroblasts; spheroids; exosomes; skin aging; microRNA
Sources: Web Of Science, ORCID
Added: November 11, 2019

2019 journal article

Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury

ADVANCED FUNCTIONAL MATERIALS, 29(4).

By: T. Su, K. Huang, H. Ma*, H. Liang, P. Dinh, J. Chen, D. Shen, T. Allen n ...

author keywords: biomimetics; drug delivery; ischemic injury; platelets; stromal cell secretome
Sources: Web Of Science, ORCID
Added: February 4, 2019

2019 journal article

microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential

JOURNAL OF CLINICAL INVESTIGATION, 129(6), 2237–2250.

By: L. Qiao*, S. Hu, S. Liu*, H. Zhang*, H. Ma, K. Huang, Z. Li, T. Su ...

Sources: Web Of Science, ORCID
Added: June 24, 2019

2018 journal article

A New Era of Cardiac Cell Therapy: Opportunities and Challenges

Advanced Healthcare Materials, 8(2), 1801011.

By: K. Huang, S. Hu & K. Cheng

author keywords: cardiac patches; cell therapy; exosomes; injury targeting; microRNA; myocardial infarction; synthetic stem cells
Sources: Web Of Science, ORCID, Crossref
Added: February 11, 2019

2018 journal article

Cardiac Stem Cell Patch Integrated with Microengineered Blood Vessels Promotes Cardiomyocyte Proliferation and Neovascularization after Acute Myocardial Infarction

ACS APPLIED MATERIALS & INTERFACES, 10(39), 33088–33096.

By: T. Su, K. Huang, M. Daniele, M. Hensley n, A. Young, J. Tang, T. Allen, A. Vandergriff n ...

author keywords: microvessels; hydrodynamic focusing; cardiac stem cells; cardiomyocyte proliferation; angiogenesis; myocardial infarction
Sources: Web Of Science, ORCID
Added: October 29, 2018

2018 journal article

Cardiac cell-integrated microneedle patch for treating myocardial infarction

SCIENCE ADVANCES, 4(11).

By: J. Tang, J. Wang, K. Huang, Y. Ye, T. Su, L. Qiao n, M. Hensley, T. Caranasos* ...

Sources: Web Of Science, ORCID
Added: December 31, 2018

2018 journal article

Concise Review: Is Cardiac Cell Therapy Dead? Embarrassing Trial Outcomes and New Directions for the Future

Stem Cells Translational Medicine, 7(4), 354–359.

By: J. Tang, J. Cores, K. Huang, X. Cui*, L. Luo*, J. Zhang n, T. Li*, L. Qian*, K. Cheng

author keywords: Myocardial injury; Stem cell therapy; Synthetic stem cells; Biomaterials
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2018 journal article

Mesenchymal Stem Cell/Red Blood Cell-Inspired Nanoparticle Therapy in Mice with Carbon Tetrachloride-Induced Acute Liver Failure

ACS Nano, 12(7), 6536–6544.

By: H. Liang n, K. Huang, T. Su n, Z. Li n, S. Hu n, P. Dinh n, E. Wrona*, C. Shao* ...

author keywords: mesenchymal stem cells; red blood cells; biomimetic; nanoparticles; membrane cloaking; liver failure
Sources: Crossref, ORCID
Added: September 10, 2019

2018 journal article

Pretargeting and Bioorthogonal Click Chemistry-Mediated Endogenous Stem Cell Homing for Heart Repair

ACS NANO, 12(12), 12193–12200.

By: Z. Li, D. Shen, S. Hu, T. Su, K. Huang, F. Liu n, L. Hou*, K. Cheng

author keywords: pretargeting; bioorthogonal click chemistry; heart repair; endogenous stem cells; engineered antibodies
Sources: Web Of Science, ORCID
Added: January 14, 2019

2018 journal article

Targeted Treatment of Ischemic and Fibrotic Complications of Myocardial Infarction Using a Dual-Delivery Microgel Therapeutic

ACS Nano, 12(8), 7826–7837.

By: E. Mihalko, K. Huang, E. Sproul, K. Cheng & A. Brown

author keywords: microgels; myocardial infarction; fibrin; fibrinolytic; fibrosis; ischemia reperfusion; drug delivery
Sources: Crossref, ORCID
Added: February 21, 2020

2018 journal article

Targeted repair of heart injury by stem cells fused with platelet nanovesicles

NATURE BIOMEDICAL ENGINEERING, 2(1), 17–26.

By: J. Tang, T. Su, K. Huang, P. Dinh, Z. Wang*, A. Vandergriff, M. Hensley, J. Cores ...

Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Targeting regenerative exosomes to myocardial infarction using cardiac homing peptide

THERANOSTICS, 8(7), 1869–1878.

By: A. Vandergriff, K. Huang, D. Shen*, S. Hu, M. Hensley, T. Caranasos*, L. Qian*, K. Cheng

author keywords: Targeting; exosomes; cardiac regeneration; heart disease; myocardial infarction
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Hydrodynamically Controlled Fabrication of Three-dimensional Microvasculature for Engineering Thick Vascularized Cardiac Tissues

Tissue Engineering Part A, 23(S1), 134–134.

By: T. Su, M. Daniele, P. Erb, K. Huang, M. Hensley, A. Young, T. Allen, A. Vandergriff ...

Event: 2017 TERMIS at Charlotte, NC on December 3-6, 2017

Source: NC State University Libraries
Added: May 23, 2023

Funding History

Funding history based on the linked ORCID record. Updated: November 18th, 2022 16:38

grant July 1, 2021 - June 30, 2024
A Minimal-Invasively Injectable SynCSC Adhesive (MISA) for Aging Rats with Heart Failure
American Heart Association