Ke Huang

In vivo trafficking of cancer-derived exosomes and their role in metastasis

Wei, S.-Y., Shelton, S. E., Chen, Y.-C., & Huang, K. (2025, January 18). Extracellular Vesicle.

Minimally invasive snakebite inspired microneedle delivery system for internal organs

Mei, X., Zhu, D., Li, J., Huang, K., Hu, S., Xing, M., & Cheng, K. (2025, March 24). Bioactive Materials, Vol. 49, pp. 576–585.

An infusible biologically active adhesive for chemotherapy-related heart failure in elderly rats

Yao, J., Li, J., Zhu, D., Li, Y., Tasoudis, P., Liu, S., … Huang, K. (2024, July 26). Bioactive Materials, Vol. 40, pp. 571–581.

Inhalable Stem Cell Exosomes Promote Heart Repair After Myocardial Infarction

Li, J., Sun, S., Zhu, D., Mei, X., Lyu, Y., Huang, K., … Cheng, K. (2024, August 26). Circulation, Vol. 150, pp. 710–723.

On-demand drug delivery bioelectronics through a water-processable low dimensional highly conductive MXene layer

Kwon, H.-jin, Wu, Y., Li, Y., Yuan, G., Lopez, R., Huang, K., & Bai, W. (2024, January 1). Lab on a Chip, Vol. 6.

Orbit symmetry breaking in MXene implements enhanced soft bioelectronic implants

Wu, Y., Li, Y., Liu, Y., Zhu, D., Xing, S., Lambert, N., … Bai, W. (2024, October 2). Science Advances, Vol. 10.

Symmetry engineering in 2D bioelectronics facilitating augmented biosensing interfaces

Wu, Y., Liu, Y., Li, Y., Wei, Z., Xing, S., Wang, Y., … Bai, W. (2024, November 18). Proceedings of the National Academy of Sciences, Vol. 121.

An inhaled bioadhesive hydrogel to shield non-human primates from SARS-CoV-2 infection

Nature Materials, 2.

Intrapericardial long non-coding RNA–Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair

European Heart Journal, 44(19), 1748–1760.

Techniques for navigating postsurgical adhesions: Insights into mechanisms and future directions

Chen, J., Tang, X., Wang, Z., Perez, A., Yao, B., Huang, K., … King, M. W. (2023, June 26). Bioengineering & Translational Medicine, Vol. 6.

Wound‐triggered shape change microgels for the development of enhanced biomimetic function platelet‐like particles

Journal of Biomedical Materials Research Part A, 112(4), 613–624.

3D Bioprinting Technology – One Step Closer Towards Cardiac Tissue Regeneration

Frontiers in Materials, 8.

Inhalable dry powder mRNA vaccines based on extracellular vesicles

Matter, 5(9), 2960–2974.

Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3

Zhu, D., Liu, S., Huang, K., Wang, Z., Hu, S., Li, J., … Cheng, K. (2022, October 13). Circulation Research, Vol. 10, pp. E135–E150.

Minimally invasive delivery of a hydrogel-based exosome patch to prevent heart failure

Cheng, G., Zhu, D., Huang, K., & Caranasos, T. G. (2022, May 4). Journal of Molecular and Cellular Cardiology, Vol. 8, pp. 113–121.

Sealing the heart from the inside out

Nature Biomedical Engineering, 7(2), 87–88.

Skin‐Interfaced Deep‐Tissue Sensing Patch via Microneedle Waveguides

Liu, Y., Menon, R., Putcha, A., Huang, K., Bonilla, L., Vora, R., … Bai, W. (2022, June 29). Advanced Materials Technologies, Vol. 6.

Skin‐Interfaced Deep‐Tissue Sensing Patch via Microneedle Waveguides (Adv. Mater. Technol. 9/2022)

Advanced Materials Technologies, 7(9), 2270058.

A Minimally Invasive Exosome Spray Repairs Heart after Myocardial Infarction

Yao, J., Huang, K., Zhu, D., Chen, T., Jiang, Y., Zhang, J., … Cheng, K. (2021, June 21). ACS Nano, Vol. 7, pp. 11099–11111.

A fluid-powered refillable origami heart pouch for minimally invasive delivery of cell therapies in rats and pigs

Mei, X., Zhu, D., Li, J., Huang, K., Hu, S., Li, Z., … Cheng, K. (2021, November 1). Med, Vol. 11, pp. 1253–1268.e4.

A stem cell-derived ovarian regenerative patch restores ovarian function and rescues fertility in rats with primary ovarian insufficiency

Zhang, S., Zhu, D., Li, Z., Huang, K., Hu, S., Lutz, H., … Cheng, K. (2021, January 1). Theranostics, Vol. 11, pp. 8894–8908.

All Roads Lead to Rome (the Heart): Cell Retention and Outcomes From Various Delivery Routes of Cell Therapy Products to the Heart

Li, J., Hu, S., Zhu, D., Huang, K., Mei, X., Juan Abad, B. L., & Cheng, K. (2021, April 20). Journal of the American Heart Association, Vol. 10.

Bioengineering Technologies for Cardiac Regenerative Medicine

Frontiers in Bioengineering and Biotechnology, 9.

Cardiac Repair: Bispecific Antibody Inhalation Therapy for Redirecting Stem Cells from the Lungs to Repair Heart Injury (Adv. Sci. 1/2021)

Advanced Science, 8(1), 2170005.

Exosome-eluting stents for vascular healing after ischaemic injury

Hu, S., Li, Z., Shen, D., Zhu, D., Huang, K., Su, T., … Cheng, K. (2021, April 5). Nature Biomedical Engineering, Vol. 4, pp. 1174–1188.

Extruded Mesenchymal Stem Cell Nanovesicles Are Equally Potent to Natural Extracellular Vesicles in Cardiac Repair

Wang, X., Hu, S., Li, J., Zhu, D., Wang, Z., Cores, J., … Huang, K. (2021, November 18). ACS Applied Materials & Interfaces, Vol. 12, pp. 55767–55779.

Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem cells in myocardial infarction

Li, J., Lv, Y., Zhu, D., Mei, X., Huang, K., Wang, X., … Wang, J. (2021, August 10). Chemical Engineering Journal, Vol. 1, p. 131581.

Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair

Zhu, D., Li, Z., Huang, K., Caranasos, T. G., Rossi, J. S., & Cheng, K. (2021, March 3). Nature Communications, Vol. 12.

Publisher Correction: Exosome-eluting stents for vascular healing after ischaemic injury

Hu, S., Li, Z., Shen, D., Zhu, D., Huang, K., Su, T., … Cheng, K. (2021, April 20). Nature Biomedical Engineering, Vol. 5, p. 1239.

Resuscitating the Field of Cardiac Regeneration: Seeking Answers from Basic Biology

Advanced Biology, 6(2), 2101133.

An off-the-shelf artificial cardiac patch improves cardiac repair after myocardial infarction in rats and pigs

Science Translational Medicine, 12(538).

Cardiac Stromal Cell Patch Integrated with Engineered Microvessels Improves Recovery from Myocardial Infarction in Rats and Pigs

ACS Biomaterials Science & Engineering, 6(11), 6309–6320.

Dermal exosomes containing miR-218-5p promote hair regeneration by regulating β-catenin signaling

Hu, S., Li, Z., Lutz, H., Huang, K., Su, T., Cores, J., … Cheng, K. (2020, July 24). Science Advances, Vol. 6.

Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

Dinh, P.-U. C., Paudel, D., Brochu, H., Popowski, K. D., Gracieux, M. C., Cores, J., … Cheng, K. (2020, February 28). Nature Communications, Vol. 11.

Targeted anti–IL-1β platelet microparticles for cardiac detoxing and repair

Li, Z., Hu, S., Huang, K., Su, T., Cores, J., & Cheng, K. (2020, February 6). Science Advances, Vol. 6.

Tumor cell-derived exosomes home to their cells of origin and can be used as Trojan horses to deliver cancer drugs

Qiao, L., Hu, S., Huang, K., Su, T., Li, Z., Vandergriff, A., … Cheng, K. (2020, January 1). Theranostics, Vol. 10, pp. 3474–3487.

Antibody-Armed Platelets for the Regenerative Targeting of Endogenous Stem Cells

Shen, D., Li, Z., Hu, S., Huang, K., Su, T., Liang, H., … Cheng, K. (2019, February 18). Nano Letters, Vol. 19, pp. 1883–1891.

Bispecific Antibody Therapy for Effective Cardiac Repair through Redirection of Endogenous Stem Cells

Huang, K., Li, Z., Su, T., Shen, D., Hu, S., & Cheng, K. (2019, May 31). Advanced Therapeutics, Vol. 2.

Hyaluronic Acid Hydrogel Integrated with Mesenchymal Stem Cell‐Secretome to Treat Endometrial Injury in a Rat Model of Asherman's Syndrome

Liu, F., Hu, S., Yang, H., Li, Z., Huang, K., Su, T., … Cheng, K. (2019, May 30). Advanced Healthcare Materials, Vol. 8.

Inhalation of Lung Spheroid Cell-Secretome and Exosomes Promotes Therapeutic Lung Repair in Rodent Models of Pulmonary Fibrosis

In A29 Emerging Concepts in Lung Fibrosis (Vol. 199, pp. 1225–1225).

Needle-Free Injection of Exosomes Derived from Human Dermal Fibroblast Spheroids Ameliorates Skin Photoaging

Hu, S., Li, Z., Cores, J., Huang, K., Su, T., Dinh, P.-U., & Cheng, K. (2019, August 26). ACS Nano, Vol. 13, pp. 11273–11282.

microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential

Qiao, L., Hu, S., Liu, S., Zhang, H., Ma, H., Huang, K., … Cheng, K. (2019, April 28). Journal of Clinical Investigation, Vol. 129, pp. 2237–2250.

A New Era of Cardiac Cell Therapy: Opportunities and Challenges

Advanced Healthcare Materials, 8(2), 1801011.

Cardiac Stem Cell Patch Integrated with Microengineered Blood Vessels Promotes Cardiomyocyte Proliferation and Neovascularization after Acute Myocardial Infarction

ACS Applied Materials & Interfaces, 10(39), 33088–33096.

Cardiac cell–integrated microneedle patch for treating myocardial infarction

Tang, J., Wang, J., Huang, K., Ye, Y., Su, T., Qiao, L., … Cheng, K. (2018, November 2). Science Advances, Vol. 4.

Concise Review: Is Cardiac Cell Therapy Dead? Embarrassing Trial Outcomes and New Directions for the Future

Stem Cells Translational Medicine, 7(4), 354–359.

Mesenchymal Stem Cell/Red Blood Cell-Inspired Nanoparticle Therapy in Mice with Carbon Tetrachloride-Induced Acute Liver Failure

ACS Nano, 12(7), 6536–6544.

Platelet‐Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury

Su, T., Huang, K., Ma, H., Liang, H., Dinh, P. U., Chen, J., … Cheng, K. (2018, November 13). Advanced Functional Materials, Vol. 29.

Pretargeting and Bioorthogonal Click Chemistry-Mediated Endogenous Stem Cell Homing for Heart Repair

Li, Z., Shen, D., Hu, S., Su, T., Huang, K., Liu, F., … Cheng, K. (2018, December 4). ACS Nano, Vol. 12, pp. 12193–12200.

Targeted Treatment of Ischemic and Fibrotic Complications of Myocardial Infarction Using a Dual-Delivery Microgel Therapeutic

ACS Nano, 12(8), 7826–7837.

Targeted repair of heart injury by stem cells fused with platelet nanovesicles

Nature Biomedical Engineering, 2(1), 17–26.

Targeting regenerative exosomes to myocardial infarction using cardiac homing peptide

Vandergriff, A., Huang, K., Shen, D., Hu, S., Hensley, M. T., Caranasos, T. G., … Cheng, K. (2018, January 1). Theranostics, Vol. 8, pp. 1869–1878.

Hydrodynamically Controlled Fabrication of Three-dimensional Microvasculature for Engineering Thick Vascularized Cardiac Tissues

Tissue Engineering Part A, 23(S1), 134–134.