@article{adoteye_banks_cross_eytcheson_flores_leblanc_nguyen_ross_smith_stemkovski_et al._2015, title={Statistical validation of structured population models for Daphnia magna}, volume={266}, ISSN={0025-5564}, url={http://dx.doi.org/10.1016/j.mbs.2015.06.003}, DOI={10.1016/j.mbs.2015.06.003}, abstractNote={In this study we use statistical validation techniques to verify density-dependent mechanisms hypothesized for populations of Daphnia magna. We develop structured population models that exemplify specific mechanisms and use multi-scale experimental data in order to test their importance. We show that fecundity and survival rates are affected by both time-varying density-independent factors, such as age, and density-dependent factors, such as competition. We perform uncertainty analysis and show that our parameters are estimated with a high degree of confidence. Furthermore, we perform a sensitivity analysis to understand how changes in fecundity and survival rates affect population size and age-structure.}, journal={Mathematical Biosciences}, publisher={Elsevier BV}, author={Adoteye, Kaska and Banks, H.T. and Cross, Karissa and Eytcheson, Stephanie and Flores, Kevin B. and LeBlanc, Gerald A. and Nguyen, Timothy and Ross, Chelsea and Smith, Emmaline and Stemkovski, Michael and et al.}, year={2015}, month={Aug}, pages={73–84} } @article{banks_baraldi_cross_flores_mcchesney_poag_thorpe_2015, title={UNCERTAINTY QUANTIFICATION IN MODELING HIV VIRAL MECHANICS}, volume={12}, ISSN={["1551-0018"]}, DOI={10.3934/mbe.2015.12.937}, abstractNote={We consider an in-host model for HIV-1 infection dynamics developed and validated with patient data in earlier work [7]. We revisit the earlier model in light of progress over the last several years in understanding HIV-1 progression in humans. We then consider statistical models to describe the data and use these with residual plots in generalized least squares problems to develop accurate descriptions of the proper weights for the data. We use recent parameter subset selection techniques [5,6] to investigate the impact of estimated parameters on the corresponding selection scores. Bootstrapping and asymptotic theory are compared in the context of confidence intervals for the resulting parameter estimates.}, number={5}, journal={MATHEMATICAL BIOSCIENCES AND ENGINEERING}, author={Banks, H. T. and Baraldi, Robert and Cross, Karissa and Flores, Kevin and Mcchesney, Christina and Poag, Laura and Thorpe, Emma}, year={2015}, month={Oct}, pages={937–964} } @inproceedings{baraldi_cross_mcchesney_poag_thorpe_flores_banks_2014, title={Uncertainty quantification for a model of HIV-1 patient response to antiretroviral therapy interruptions}, booktitle={2014 american control conference (acc)}, author={Baraldi, R. and Cross, K. and McChesney, C. and Poag, L. and Thorpe, E. and Flores, K. B. and Banks, H. T.}, year={2014}, pages={2753–2758} }