Kate Hepworth

Also known as: Kate Hepworth; Kate L. Hepworth; Kate Hepworth-Warren

Works (24)

Updated: April 4th, 2024 05:32

2024 article

Concurrent Streptococcus equi subsp. equi infection, purpura haemorrhagica and immune-mediated myositis in a Quarter Horse filly

Hepworth-Warren, K. L., Young, K. A. S., Armwood, A., Roessner, H., & Veerasammy, B. (2024, February 18). EQUINE VETERINARY EDUCATION, Vol. 2.

By: K. Hepworth-Warren  n, K. Young n, A. Armwood n , H. Roessner n  & B. Veerasammy  n

author keywords: horse; guttural pouch empyema; MYH1 mutation; Quarter Horse; strangles
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 4, 2024

2023 journal article

General anesthesia does not induce ultrasonographic changes in the pleura of healthy adult horses anesthetized for elective magnetic resonance imaging

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 261(4), 500–504.

By: K. Hepworth-Warren, N. Nelson, K. Dembek & K. Young

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 9, 2023

2023 article

Ingesta-associated choledocholithiasis in horses: 2 cases and literature review

Linn-Peirano, S. C. C., Hepworth-Warren, K., Kinsella, H., Diaz-Campos, D., Brenseke, B. M. M., Cianciolo, R. E. E., … Schreeg, M. E. E. (2023, May 26). JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, Vol. 5.

By: S. Linn-Peirano, K. Hepworth-Warren  n, H. Kinsella *, D. Diaz-Campos*, B. Brenseke n, R. Cianciolo *, E. Schroeder*, M. Schreeg n

author keywords: cholangiohepatitis; cholangitis; cholelithiasis; colic; foreign body; horses; liver; plant
MeSH headings : Horses; Animals; Female; Choledocholithiasis / veterinary; Choledocholithiasis / complications; Colic / complications; Colic / veterinary; Cholangitis / veterinary; Fibrosis; Fever / complications; Fever / veterinary; Horse Diseases / pathology
TL;DR: The clinical, gross, histologic, and microbiologic features of this condition in 2 horses and compare the features to 2 previous cases are described. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 19, 2023

2023 journal article

Risk factors associated with an outbreak of equine coronavirus at a large farm in North Carolina

FRONTIERS IN VETERINARY SCIENCE, 10.

By: K. Hepworth-Warren  n, S. Erwin  n, C. Moore, J. Talbot, K. Young n, M. Neault*, J. Haugland*, J. Robertson n , A. Blikslager n 

author keywords: ECoV; coronavirus; colic; diarrhea; small colon impaction
TL;DR: Clinical findings and risk factors for ECoV infection many of which were associated with intensive management of show horses were described, and clinicians should be aware that clinical signs vary and can include severe colic. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 4, 2023

2023 article

Utility of serum amyloid A in monitoring clinical response to antimicrobial treatment in horses with bacterial pneumonia

Hepworth-Warren, K. L., Estell, K., Cowles, B., Amodie, D., & Crisman, M. (2023, July 31). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 7.

By: K. Hepworth-Warren  n, K. Estell *, B. Cowles*, D. Amodie* & M. Crisman *

author keywords: acute phase; antimicrobials; equine; microbiology; pleuropneumonia; respiratory
TL;DR: SAA concentration decreased significantly over the course of treatment and correlated with clinical improvement of pneumonia whereas fibrinogen, neutrophil, and WBC counts did not. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 14, 2023

2022 journal article

Comparison of Fluid Analysis and Cytologic Findings of Cerebrospinal Fluid Between Three Collection Sites in Adult Equids With Neurological Disease

FRONTIERS IN VETERINARY SCIENCE, 9.

By: K. Young n, K. Hepworth-Warren  n & K. Dembek n

author keywords: equine protozoal myeloencephalitis (EPM); cytopathology; atlanto-occipital; atlantoaxial; lumbosacral
TL;DR: There were minimal differences in multiple other parameters between sites, which are likely clinically insignificant and have clinical implications due to the importance of comparative diagnostics and its potential impact on cytologic evaluation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 23, 2022

2022 journal article

Comparison of thoracic ultrasonography and thoracic radiography between healthy adult horses and horses with bacterial pneumonia using a novel, objective ultrasonographic scoring system

FRONTIERS IN VETERINARY SCIENCE, 9.

By: K. Hepworth-Warren  n, N. Nelson n, K. Dembek n & K. Young n

author keywords: equine pneumonia; thoracic radiography; imaging; equine pleuropneumonia; ultrasonography
TL;DR: TUS appears to be an acceptable stand-alone imaging modality for diagnosis of bacterial pneumonia in horses when radiography is not practical and to validate a novel, objective scoring system for TUS in adult horses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 7, 2022

2021 review

Revisiting the use of hydroxyethyl starch solutions in equine fluid therapy

[Review of ]. EQUINE VETERINARY EDUCATION, 33(8), 436–443.

By: K. Hepworth-Warren  n

author keywords: horse; hydroxyethyl starch; colloid osmotic pressure; oncotic pressure; colloid
TL;DR: The information presented here serves to review the physiology of oncotic pressure and the rationale behind colloid use, specifically HES solutions and the foundation of arguments against the use of HES are summarized. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 24, 2020

2017 journal article

Measured and calculated variables of global oxygenation in healthy neonatal foals

American Journal of Veterinary Research, 78(2), 230–238.

By: D. Wong, K. Hepworth-Warren, B. Sponseller, J. Howard & C. Wang

MeSH headings : Animals; Animals, Newborn / physiology; Blood Gas Analysis / veterinary; Carbon Dioxide / blood; Horses / physiology; Lactic Acid / blood; Oxygen / blood; Reference Values
TL;DR: This study provided information about several variables that reflect global oxygenation in healthy neonatal foals that may aid in treatment decisions and prognosis of clinical outcome for critically ill foals. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 20, 2019

2016 journal article

Macrophage effector responses of horses are influenced by expression of CD154

Veterinary Immunology and Immunopathology, 180, 40–44.

By: B. Sponseller*, S. Clark*, J. Gilbertie *, D. Wong *, K. Hepworth* , S. Wiechert*, P. Chandramani*, B. Sponseller * ...

author keywords: CD154; Reactive intermediates; Equine
MeSH headings : Animals; CD40 Antigens / physiology; CD40 Ligand / genetics; CD40 Ligand / physiology; CHO Cells; Coculture Techniques; Cricetinae; Cricetulus; Horses / immunology; Macrophages / immunology; Superoxides / metabolism
TL;DR: The cloned and expressed recombinant equine CD154 (reqCD154) in Chinese Hamster Ovary indicates that regulation of CD154 expression plays a role in innate host defenses. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 28, 2019

2016 journal article

Magnetic resonance imaging of presumptive neonatal encephalopathy in a foal

Equine Veterinary Education, 29(10), 534–538.

By: D. Wong *, N. Jeffery *, K. Hepworth-Warren *, S. Wiechert * & K. Miles *

author keywords: horse; MRI; hypoxic ischaemic encephalopathy; cardiopulmonary cerebral resuscitation; foal
TL;DR: Findings on MRI were consistent with the counterpart disease in infants and are the first to document MRI changes in a foal with neonatal encephalopathy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 28, 2019

2016 journal article

Septic peritonitis in a Percheron mare associated with Clostridium haemolyticum

Equine Veterinary Education, 29(11), 603–608.

By: K. Hepworth-Warren *, B. Hay Kraus*, D. Wong *, A. Krull* & G. Metcalf*

author keywords: horse; tetrastarch; hypoalbuminaemia; hypoalbuminaemia; oncotic pressure; ileus; colic
TL;DR: The mare was administered a low molecular weight/low molar substitution hydroxyethyl starch solution in conjunction with other therapies that resulted in marked improvement of clinical signs and the beneficial effects of tetrastarch administration in a clinical case with severe hypoalbuminaemia and ventral oedema. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 20, 2019

2015 journal article

Bacterial isolates, antimicrobial susceptibility patterns, and factors associated with infection and outcome in foals with septic arthritis: 83 cases (1998–2013)

Journal of the American Veterinary Medical Association, 246(7), 785–793.

By: K. Hepworth-Warren, D. Wong, C. Fulkerson, C. Wang & Y. Sun

MeSH headings : Aging; Animals; Arthritis, Infectious / microbiology; Arthritis, Infectious / mortality; Arthritis, Infectious / therapy; Arthritis, Infectious / veterinary; Bacteria / drug effects; Bacteria / isolation & purification; Bacterial Infections / microbiology; Bacterial Infections / mortality; Bacterial Infections / therapy; Bacterial Infections / veterinary; Drug Resistance, Bacterial; Horse Diseases / microbiology; Horse Diseases / mortality; Horse Diseases / pathology; Horse Diseases / therapy; Horses; Retrospective Studies
TL;DR: The frequency with which certain bacterial agents were isolated from septic joints may be beneficial for the empirical treatment of septic arthritis in foals and the positive association between survival rate and plasma fibrinogen concentration may have prognostic value in a clinical setting. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 28, 2019

2015 journal article

Effects of administration of a synthetic low molecular weight/ low molar substitution hydroxyethyl starch solution in healthy neonatal foals

Canadian Veterinary Journal, 56, 1069–1074.

By: K. Hepworth-Warren, D. Wong, B. Hay-Kraus, C. Wang & Y. Sun

Source: NC State University Libraries
Added: December 22, 2020

2015 journal article

Pathology in Practice

Journal of the American Veterinary Medical Association, 247(1), 55–57.

By: D. Wong, E. Whitley, K. Hepworth*  & B. Sponseller

MeSH headings : Abscess / microbiology; Abscess / pathology; Abscess / veterinary; Animals; Female; Horse Diseases / microbiology; Horse Diseases / pathology; Horses; Klebsiella Infections / diagnosis; Klebsiella Infections / pathology; Klebsiella Infections / veterinary; Klebsiella pneumoniae / isolation & purification; Osteomyelitis / diagnosis; Osteomyelitis / pathology; Osteomyelitis / veterinary; Spine / pathology
Sources: Crossref, NC State University Libraries
Added: August 29, 2019

2015 journal article

Use of Alprazolam to Facilitate Mare-Foal Bonding in an Aggressive Postparturient Mare

Journal of Veterinary Internal Medicine, 29(1), 414–416.

By: D. Wong *, C. Alcott*, J. Davis n, K. Hepworth* , L. Wulf* & J. Coetzee *

author keywords: Behavior; Horse; Maternal; Milk; Neonate; Nursing; Xanax
MeSH headings : Aggression / drug effects; Alprazolam / pharmacology; Animals; Animals, Newborn; Animals, Suckling; Behavior, Animal / drug effects; Female; GABA Modulators / pharmacology; Horses / physiology; Male; Maternal Behavior / drug effects; Postpartum Period
TL;DR: A healthy 11-year old, 577 kg maiden Quarter Horse mare was examined at the Lloyd Veterinary Medical Center with a 4-day old colt because the mare would bite or kick the foal when thefoal attempted to suckle, and the m Mare consistently demonstrated aggressive behavior toward the foals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

2014 journal article

Intrathoracic oesophageal perforation and secondary pleuropneumonia: Five cases

Equine Veterinary Education, 27(6), 283–290.

By: K. Hepworth-Warren *, C. Wilgenbusch*, D. Wong *, A. Fales-Williams*, S. Wiechert* & B. Sponseller*

author keywords: horse; oesophageal obstruction; choke; pleuropneumonia; oesophageal perforation; pleuritis
TL;DR: The history, clinical presentation, response to therapy and outcome of 5 cases of intrathoracic oesophageal perforation and secondary septic pleuropneumonia are described. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 20, 2019

2014 journal article

Isolation of Corynebacterium pseudotuberculosis Biovar equi from a Horse in Central Iowa

Case Reports in Veterinary Medicine, 2014, 1–3.

By: K. Hepworth-Warren *, B. Sponseller *, D. Wong * & J. Kinyon*

TL;DR: Clinical findings of two horses in Iowa that presented with pectoral abscessation are described, confirmed in one to be C. pseudotuberculosis biovar equi. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 20, 2019

2014 journal article

Metastatic Tumor in Pregnancy: Placental Germ Cell Tumor With Metastasis to the Foal

Journal of Equine Veterinary Science, 34(9), 1134–1139.

By: K. Hepworth-Warren *, D. Wong *, N. Galow-Kersh* & J. Williams*

author keywords: Germ cell tumor; Neoplasia; Metastasis; Neurologic; Placenta; Computed tomography
TL;DR: Clinical and biochemical findings were supportive of liver disease and lumbosacral injury, and Histopathologic comparison between neoplastic cells examined from the placenta and foal confirmed metastases of a germ cell tumor. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 28, 2019

2014 journal article

Pharmacokinetics and physiologic effects of alprazolam after a single oral dose in healthy mares

Journal of Veterinary Pharmacology and Therapeutics, 38(3), 301–304.

By: D. Wong *, J. Davis n, C. Alcott*, K. Hepworth-Warren *, N. Galow-Kersh*, S. Rice*, J. Coetzee *

MeSH headings : Administration, Oral; Alprazolam / administration & dosage; Alprazolam / analogs & derivatives; Alprazolam / blood; Alprazolam / pharmacokinetics; Alprazolam / pharmacology; Animals; Ataxia / chemically induced; Ataxia / veterinary; Conscious Sedation / methods; Conscious Sedation / veterinary; Female; Horses / metabolism; Hypnotics and Sedatives / administration & dosage; Hypnotics and Sedatives / blood; Hypnotics and Sedatives / pharmacokinetics; Hypnotics and Sedatives / pharmacology
TL;DR: Oral alprazolam tablets were absorbed in adult horses and no clinically relevant adverse events were observed, and further evaluation of repeated dosing and safety of administration of alpazolam to horses is warranted. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

2013 journal article

Imaging Diagnosis - Hypoglycemia Associated with Cholangiocarcinoma and Peritoneal Carcinomatosis in a Horse

Veterinary Radiology & Ultrasound, 56(1), E9–E12.

By: D. Wong *, K. Hepworth* , M. Yaeger *, K. Miles* & C. Wilgenbusch*

author keywords: abdominal; equine; hypoglycemia; neoplasia; seizures
MeSH headings : Animals; Bile Duct Neoplasms / blood; Bile Duct Neoplasms / diagnostic imaging; Bile Duct Neoplasms / veterinary; Cholangiocarcinoma / diagnostic imaging; Cholangiocarcinoma / secondary; Cholangiocarcinoma / veterinary; Female; Horse Diseases / diagnosis; Horse Diseases / diagnostic imaging; Horses; Hypoglycemia / veterinary; Lung Diseases, Interstitial / veterinary; Lymphatic Metastasis; Paraneoplastic Syndromes / veterinary; Peritoneal Neoplasms / diagnostic imaging; Peritoneal Neoplasms / secondary; Peritoneal Neoplasms / veterinary; Radiography, Thoracic / veterinary; Ultrasonography
TL;DR: An 8-year-old Thoroughbred mare presented for decreased appetite, ataxia, and weakness that was attributed to a paraneoplastic syndrome of tumor-associated hypoglycemia that has been infrequently reported in horses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: December 16, 2019

2013 journal article

Renal Replacement Therapy in Healthy Adult Horses

Journal of Veterinary Internal Medicine, 27(2), 308–316.

By: D. Wong *, D. Witty, C. Alcott*, B. Sponseller*, C. Wang * & K. Hepworth* 

author keywords: Creatinine clearance; Dialysis; Effluent; Heparin; Renal failure
MeSH headings : Acute Kidney Injury / therapy; Acute Kidney Injury / veterinary; Animals; Blood Pressure / physiology; Body Temperature / physiology; Creatinine / blood; Creatinine / urine; Female; Heart Rate / physiology; Horse Diseases / blood; Horse Diseases / physiopathology; Horse Diseases / therapy; Horse Diseases / urine; Horses; Partial Thromboplastin Time / veterinary; Platelet Count / veterinary; Prospective Studies; Prothrombin Time / veterinary; Renal Replacement Therapy / methods; Renal Replacement Therapy / veterinary; Respiratory Rate / physiology
TL;DR: Renal replacement therapy can safely and effectively be used in adult horses, and no adverse effects were detected. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 28, 2019

2013 journal article

Survival of an adult Quarter Horse gelding following bacterial meningitis caused by Escherichia coli

Equine Veterinary Education, 26(10), 507–512.

By: K. Hepworth* , D. Wong *, B. Sponseller*, C. Alcott*, B. Sponseller*, G. Ben-Shlomo *, R. Whitley*

author keywords: horse; haematogenous; nasal abscess; post traumatic blindness; skull trauma
TL;DR: This case is unique as there were multiple pathways through which bacteria may have entered the central nervous system including haematogenous spread from a nasal abscess, local extension of periocular infection or an undetected skull fracture. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 20, 2019

2013 journal article

Treatment and resolution of zilpaterol hydrochloride toxicity in a Quarter Horse gelding

Equine Veterinary Education, 26(2), 81–85.

By: K. Hepworth‐Warren * & C. Alcott*

author keywords: horse; zilpaterol; agonist; toxicity; propranolol; clenbuterol
TL;DR: This is the first documented clinical case of equine zilpaterol toxicity, and the horse presented with marked tachycardia, profuse sweating and generalised muscle fasciculations. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 20, 2019

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