Works (4)
Updated: July 5th, 2023 15:48
2011 journal article
A new model for the estimation of cell proliferation dynamics using CFSE data
JOURNAL OF IMMUNOLOGICAL METHODS, 373(1-2), 143–160.
author keywords: Cell proliferation; Cell division number; CFSE; Label structured population dynamics; Partial differential equations; Inverse problems
MeSH headings : Algorithms; Cell Division; Cell Proliferation; Flow Cytometry; Fluoresceins / metabolism; Fluorescent Dyes / metabolism; Humans; Kinetics; Leukocytes, Mononuclear / cytology; Leukocytes, Mononuclear / metabolism; Lymphocytes / cytology; Lymphocytes / metabolism; Models, Biological; Molecular Dynamics Simulation; Succinimides / metabolism
TL;DR:
A significant revision of this PDE model is presented which improves the physiological understanding of several parameters and results in a model with a strong physiological basis which is fully capable of replicating the behavior observed in the data.
(via Semantic Scholar)
open access via europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Estimation of Cell Proliferation Dynamics Using CFSE Data
BULLETIN OF MATHEMATICAL BIOLOGY, 73(1), 116–150.
author keywords: Cell proliferation; CFSE; Label structured population dynamics; Partial differential equations; Inverse problems
MeSH headings : Cell Proliferation; Flow Cytometry / methods; Flow Cytometry / statistics & numerical data; Fluoresceins; Fluorescent Dyes; Humans; In Vitro Techniques; Least-Squares Analysis; Mathematical Concepts; Models, Biological; Models, Statistical; Succinimides
TL;DR:
These investigations suggest that the new decay/label loss and time dependent effective proliferation and death rates do indeed provide improved fits of the model to data, and should prove useful in proliferation assay tracking and modeling, with numerous applications in the biomedical sciences.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
DYNAMIC SOCIAL NETWORK MODELS INCORPORATING STOCHASTICITY AND DELAYS
QUARTERLY OF APPLIED MATHEMATICS, 68(4), 783–802.
author keywords: Social networks; stochastic differential equations; delay differential equations; clustering
TL;DR:
The work in Banks, Karr, Nguyen and Samuels (2008), which demonstrated a simple dynamical system framework in which to study social network behavior, is extended to include a discrete delay, which represents the time lag that is likely required for an agent to change his/her own characteristics after interacting with an agent possessing different characteristics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Label structured cell proliferation models
APPLIED MATHEMATICS LETTERS, 23(12), 1412–1415.
author keywords: Cell proliferation; Label structured population dynamics; Partial differential equations; Moving coordinate systems
TL;DR:
A general class of cell population models that can be used to track the proliferation of cells which have been labeled with a fluorescent dye are presented and address overall label degradation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018