Kristen Messenger

Wiloch, E. E., Enomoto, H., Smith, L., Baynes, R. E., & Messenger, K. M. (2024, January 11). Pharmacokinetics of intranasal and intramuscular flunixin in healthy grower pigs. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS. https://doi.org/10.1111/jvp.13426

Colon, C., Early, P., Munana, K., Olby, N., Mariani, C., Mancini, S., … Messenger, K. (2024, March 27). Pharmacokinetics of subcutaneous ketamine administration via the Omnipod® system in dogs. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, Vol. 3. https://doi.org/10.1111/jvp.13440

Salmon, S. J., Coleman, A. E., Lynn, C. R., Sanders, J. E., & Messenger, K. M. (2024). Single- and multiple-dose pharmacokinetics of sotalol hydrochloride in healthy cats. JOURNAL OF VETERINARY CARDIOLOGY, 51, 86–96. https://doi.org/10.1016/j.jvc.2023.11.015

Wallace, A., Love, L., Gensler, C., Jacob, M., Robertson, J., & Messenger, K. (2023). Comparative growth dynamics of bacterial and fungal contaminants in bupivacaine liposomal injectable suspension, bupivacaine 0.5%, and propofol. PLOS ONE, 18(2). https://doi.org/10.1371/journal.pone.0281768

Lopez-Soriano, M., Merenda, V. R., Anderson, S., Trindade, P. H. E., Leidig, M. S., Messenger, K., … Pairis-Garcia, M. D. (2023). Efficacy of inguinal buffered lidocaine and intranasal flunixin meglumine on mitigating physiological and behavioral responses to pain in castrated piglets. FRONTIERS IN PAIN RESEARCH, 4. https://doi.org/10.3389/fpain.2023.1156873

Mercer, M. A., Davis, J. L., McKenzie, H. C., Messenger, K. M., Schaefer, E., Council-Troche, R. M. A., & Werre, S. R. (2023, February 24). Pharmacokinetics and efficacy of orally administered acetaminophen (paracetamol) in adult horses with experimentally induced endotoxemia. JOURNAL OF VETERINARY INTERNAL MEDICINE. https://doi.org/10.1111/jvim.16663

Shippy, S., Allgood, H., Messenger, K., Hernandez, J. A., Gatson, B., Bustamante, M. G. M., … Johnson, A. (2023). Pharmacokinetics and pharmacodynamics of intramuscular alfaxalone in central bearded dragons (Pogona vitticeps): effect of injection site. VETERINARY ANAESTHESIA AND ANALGESIA, 50(3), 280–288. https://doi.org/10.1016/j.vaa.2023.02.010

Papich, M. G., Madsen, M., Messenger, K., & Enomoto, H. (2022, May 6). Ceftazidime pharmacokinetics in dogs after intravenous injection and delivered with the RxActuator Mini-Infuser infusion pump. JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, Vol. 5. https://doi.org/10.1111/vec.13205

Madsen, M., Enomoto, H., Messenger, K., & Papich, M. G. (2022). Effects of housing environment on oral absorption of acetaminophen in healthy Beagles. AMERICAN JOURNAL OF VETERINARY RESEARCH, 83(1), 80–85. https://doi.org/10.2460/ajvr.21.06.0075

Koch, D. W. W., Berglund, A. K. K., Messenger, K. M. M., Gilbertie, J. M. M., Ellis, I. M. M., & Schnabel, L. V. V. (2022). Interleukin-1 beta in tendon injury enhances reparative gene and protein expression in mesenchymal stem cells. FRONTIERS IN VETERINARY SCIENCE, 9. https://doi.org/10.3389/fvets.2022.963759

Bini, G., Cohen, E. B., Chiavaccini, L., Messenger, K. M., & Bailey, K. M. (2022, January 10). Intravenous dexmedetomidine, morphine, or a combination can result in gallbladder wall thickening; with no significant association with plasma histamine concentrations. VETERINARY RADIOLOGY & ULTRASOUND, Vol. 1. https://doi.org/10.1111/vru.13056

Mancini, S. L., Early, P. J., Slater, B. M., Olby, N. J., Mariani, C. L., Munana, K. R., … Messenger, K. M. (2022). Novel subcutaneous cytarabine infusion with the Omnipod system in dogs with meningoencephalomyelitis of unknown etiology. AMERICAN JOURNAL OF VETERINARY RESEARCH, 83(9). https://doi.org/10.2460/ajvr.22.03.0046

Nixon, E., Chittenden, J. T., Baynes, R. E., & Messenger, K. M. (2022, July 14). Pharmacokinetic/pharmacodynamic modeling of ketoprofen and flunixin at piglet castration and tail-docking. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, Vol. 7. https://doi.org/10.1111/jvp.13083

Enomoto, H., Love, L., Madsen, M., Wallace, A., & Messenger, K. M. (2022, April 21). Pharmacokinetics of intravenous, oral transmucosal, and intranasal buprenorphine in healthy male dogs. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS. https://doi.org/10.1111/jvp.13056

Southern, B. L., Long, S. M., Barnes, D. N., Enomoto, H., & Messenger, K. M. (2022). Preliminary evaluation of the effects of grapiprant compared with carprofen on acute pain and inflammation following ovariohysterectomy in dogs. AMERICAN JOURNAL OF VETERINARY RESEARCH, 83(7). https://doi.org/10.2460/ajvr.21.10.0162

Chang, K., Barletta, M., Messenger, K. M., Sakai, D. M., Reed, R. A., & Quandt, J. E. (2022). The effect of a ketamine constant rate infusion on cardiovascular variables in sheep anesthetized at the minimum alveolar concentration of sevoflurane that blunts adrenergic responses. AMERICAN JOURNAL OF VETERINARY RESEARCH, 83(3), 205–211. https://doi.org/10.2460/ajvr.21.08.0129

Nixon, E., Carlson, A. R., Routh, P. A., Hernandez, L., Almond, G. W., Baynes, R. E., & Messenger, K. M. (2021). Comparative effects of nonsteroidal anti-inflammatory drugs at castration and tail-docking in neonatal piglets. PLOS ONE, 16(11). https://doi.org/10.1371/journal.pone.0254409

Enomoto, H., Yeatts, J., Carbajal, L., Krishnan, B. R., Madan, J. P., Laumas, S., … Messenger, K. M. (2021). In vivo assessment of a delayed release formulation of larazotide acetate indicated for celiac disease using a porcine model. PLOS ONE, 16(4). https://doi.org/10.1371/journal.pone.0249179

Slifer, Z. M., Hernandez, L., Pridgen, T. A., Carlson, A. R., Messenger, K. M., Madan, J., … Blikslager, A. T. (2021). Larazotide acetate induces recovery of ischemia-injured porcine jejunum via repair of tight junctions. PLOS ONE, 16(4). https://doi.org/10.1371/journal.pone.0250165

Belda, B., Ramos-Vara, J., Messenger, K. M., & Risselada, M. (2021, August 10). Pharmacokinetic and safety assessment of carboplatin-impregnated calcium sulfate hemihydrate beads in eight rats. VETERINARY SURGERY. https://doi.org/10.1111/vsu.13712

Tracy, A., Lynch, A., Messenger, K., Vaden, S., & Vigani, A. (2021, December 14). Use of extracorporeal therapy in a dog with heatstroke. JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, Vol. 12. https://doi.org/10.1111/vec.13169

Nixon, E., Almond, G. W., Baynes, R. E., & Messenger, K. M. (2020). Comparative Plasma and Interstitial Fluid Pharmacokinetics of Meloxicam, Flunixin, and Ketoprofen in Neonatal Piglets. FRONTIERS IN VETERINARY SCIENCE, 7. https://doi.org/10.3389/fvets.2020.00082

Barletta, M., Quandt, J. E., Reed, R. A., Hofmeister, E. H., & Messenger, K. M. (2020). Determination of the minimum alveolar concentration of sevoflurane that blunts adrenergic responses and the effect of a constant rate infusion of ketamine in sheep. RESEARCH IN VETERINARY SCIENCE, 128, 230–235. https://doi.org/10.1016/j.rvsc.2019.12.011

Fick, M. E., Messenger, K. M., & Vigani, A. (2020). Efficacy of a single session in-series hemoperfusion and hemodialysis in the management of carprofen overdose in two dogs. JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 30(2), 226–231. https://doi.org/10.1111/vec.12931

Smith, P., Tolbert, M. K., Gould, E., Taylor, A., Knych, H., & Messenger, K. (2020). Pharmacokinetics, sedation and hemodynamic changes following the administration of oral transmucosal detomidine gel in cats. JOURNAL OF FELINE MEDICINE AND SURGERY, 22(12), 1184–1190. https://doi.org/10.1177/1098612X20917305

Carlson, A. R., Nixon, E., Jacob, M. E., & Messenger, K. M. (2020). Sterility and concentration of liposomal bupivacaine single-use vial when used in a multiple-dose manner. VETERINARY SURGERY, 49(4), 772–777. https://doi.org/10.1111/vsu.13380

Bennett, K. J., Seddighi, R., Moorhead, K. A., Messenger, K., Cox, S. K., Sun, X., … Doherty, T. J. (2019). Effect of fentanyl on the induction dose and minimum infusion rate of alfaxalone preventing movement in dogs. VETERINARY ANAESTHESIA AND ANALGESIA, 46(2), 173–181. https://doi.org/10.1016/j.vaa.2018.10.006

Kruse, T. N., Messenger, K. M., Bowman, A. S., Aarnes, T. K., Wittum, T. E., & Flint, M. (2019). Pharmacokinetics and pharmacodynamics of alfaxalone after a single intramuscular or intravascular injection in mallard ducks (Anas platyrhynchos). JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 42(6), 713–721. https://doi.org/10.1111/jvp.12804

Madsen, M., Messenger, K., & Papich, M. G. (2019). Pharmacokinetics of levofloxacin following oral administration of a generic levofloxacin tablet and intravenous administration to dogs. AMERICAN JOURNAL OF VETERINARY RESEARCH, 80(10), 957–962. https://doi.org/10.2460/ajvr.80.10.957

Bennett, K., Seddighi, R., Moorhead, K., Messenger, K., Cox, S., Sun, X., … Doherty, T. (2018). Effect of fentanyl on the induction dose and minimum infusion rate of alfaxalone preventing movement in female dogs. Veterinary Anaesthesia and Analgesia, 45(6), 885.e2. https://doi.org/10.1016/J.VAA.2018.09.008

Gulledge, B. M., Messenger, K. M., Cornell, K. K., Lindell, H., & Schmiedt, C. W. (2018). Pharmacokinetic comparison of two buprenorphine formulations after buccal administration in healthy male cats. JOURNAL OF FELINE MEDICINE AND SURGERY, 20(4), 312–318. https://doi.org/10.1177/1098612x17710843

Oda, A., Messenger, K. M., Carbajal, L., Posner, L. P., Gardner, B. R., Hammer, S. H., … Bailey, K. M. (2018). Pharmacokinetics and pharmacodynamic effects in koi carp (Cyprinus carpio) following immersion in propofol. VETERINARY ANAESTHESIA AND ANALGESIA, 45(4), 529–538. https://doi.org/10.1016/j.vaa.2018.02.005

Barletta, M., Ostenkamp, S. M., Taylor, A. C., Quandt, J., Lascelles, B. D. X., & Messenger, K. M. (2018). The pharmacokinetics and analgesic effects of extended-release buprenorphine administered subcutaneously in healthy dogs. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 41(4), 502–512. https://doi.org/10.1111/jvp.12497

Pastina, B., Early, P. J., Bergman, R. L., Nettifee, J., Maller, A., Bray, K. Y., … Messenger, K. M. (2018). The pharmacokinetics of cytarabine administered subcutaneously, combined with prednisone, in dogs with meningoencephalomyelitis of unknown etiology. Journal of Veterinary Pharmacology & Therapeutics, 41(5), 638–643. https://doi.org/10.1111/jvp.12667

Barletta, M., Messenger, K., Hofmeister, E., & Quandt, J. (2017). Determination of MACBAR of sevoflurane and evaluation of the effects of a ketamine constant rate infusion on sevoflurane MACBAR in sheep. Veterinary Anaesthesia and Analgesia, 44(1), 195.e3. https://doi.org/10.1016/J.VAA.2016.12.035

Barletta, M., Messenger, K., Smith, M., Thoresen, M., Peroni, J., & Quandt, J. (2017). Evaluation of cardiovascular variables in sheep anesthetized with sevoflurane in combination with ketamine CRI. Veterinary Anaesthesia and Analgesia, 44(5), 1262.e11–1262.e12. https://doi.org/10.1016/J.VAA.2017.09.024

Gruen, M. E., Messenger, K. M., Thomson, A. E., Griffith, E. H., Aldrich, L. A., Vaden, S., & Lascelles, B. D. X. (2017). Evaluation of serum cytokines in cats with and without degenerative joint disease and associated pain. Veterinary Immunology and Immunopathology, 183, 49–59. https://doi.org/10.1016/J.VETIMM.2016.12.007

Papich, M. G., & Messenger, K. (2017). Non-Steroidal Anti-Inflammatory Drugs. In Veterinary Anesthesia and Analgesia (pp. 227–243). https://doi.org/10.1002/9781119421375.ch12

Williams, M. D., Long, C. T., Durrant, J. R., McKeon, G. P., Shive, H. R., Griffith, E. H., … Fish, R. E. (2017). Oral transmucosal detomidine gel in New Zealand white rabbits (Oryctolagus cuniculus). Journal of the American Association for Laboratory Animal Science, 56(4), 436–442.

Ostenkamp, S., Barletta, M., Quandt, J., Lascelles, D., & Messenger, K. (2017). Pharmacokinetics and pharmacodynamics of an extended-release buprenorphine formulation in dogs. Veterinary Anaesthesia and Analgesia, 44(1), 195.e6. https://doi.org/10.1016/J.VAA.2016.12.042

Smith, P., Messenger, K., Gould, E., Knych, H., & Tolbert, M. (2017). Pharmacokinetics, sedation, and hemodynamic changes following administration of oral transmucosal detomidine gel in cats. Veterinary Anaesthesia and Analgesia, 44(1), 195.e5–195.e6. https://doi.org/10.1016/J.VAA.2016.12.040

Early, P. J., Crook, K. I., Williams, L. M., Davis, E. G., Munana, K. R., Papich, M. G., & Messenger, K. M. (2017). Plasma and serum concentrations of cytarabine administered via continuous intravenous infusion to dogs with meningoencephalomyelitis of unknown etiology. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 40(4), 411–414. https://doi.org/10.1111/jvp.12360

Oda, A., Messenger, K., Carbajal, L., Gardner, B., Hammer, S., Cerreta, A., … Bailey, K. (2017). Plasma propofol concentrations and pharmacodynamic effects in koi carp ( Cyprinus carpio ) following exposure via immersion. Veterinary Anaesthesia and Analgesia, 44(5), 1262.e4–1262.e5. https://doi.org/10.1016/J.VAA.2017.09.009

Gruen, M. E., Messenger, K. M., Thomson, A. E., Griffith, E. H., Paradise, H., Vaden, S., & Lascelles, B. D. X. (2016). A comparison of serum and plasma cytokine values using a multiplexed assay in cats. Veterinary Immunology and Immunopathology, 182, 69–73. https://doi.org/10.1016/J.VETIMM.2016.10.003

Risselada, M., Marcellin-Little, D. J., Messenger, K. M., Griffith, E., Davidson, G. S., & Papich, M. G. (2016). Assessment of in vitro release of carboplatin from six carrier media. AMERICAN JOURNAL OF VETERINARY RESEARCH, 77(12), 1381–1386. https://doi.org/10.2460/ajvr.77.12.1381

Messenger, K. M., Wofford, J. A., & Papich, M. G. (2016). Carprofen pharmacokinetics in plasma and in control and inflamed canine tissue fluid using in vivo ultrafiltration. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 39(1), 32–39. https://doi.org/10.1111/jvp.12233

Curto, E., Messenger, K. M., Salmon, J. H., & Gilger, B. C. (2016). Cytokine and chemokine profiles of aqueous humor and serum in horses with uveitis measured using multiplex bead immunoassay analysis. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 182, 43–51. https://doi.org/10.1016/j.vetimm.2016.09.008

Messenger, K. M., Hopfensperger, M., Knych, H. K., & Papich, M. G. (2016). Pharmacokinetics of detomidine following intravenous or oral-transmucosal administration and sedative effects of the oral-transmucosal treatment in dogs. AMERICAN JOURNAL OF VETERINARY RESEARCH, 77(4), 413–420. https://doi.org/10.2460/ajvr.77.4.413

Jarrett, M. A., Bailey, K. M., Messenger, K. M., Prange, T., Gaines, B., & Posner, L. P. (2016). Recovery of horses from general anesthesia following induction with either propofol or midazolam followed by ketamine. In Journal of the American Veterinary Medical Association (Vol. 253, pp. 101–107). https://doi.org/10.2460/javma.253.1.101

Parkinson, S., Tolbert, K., Messenger, K., Odunayo, A., Brand, M., Davidson, G., … Papich, M. G. (2015). Evaluation of the Effect of Orally Administered Acid Suppressants on Intragastric pH in Cats. JOURNAL OF VETERINARY INTERNAL MEDICINE, 29(1), 104–112. https://doi.org/10.1111/jvim.12493

Phillips, B. E., Harms, C. A., & Messenger, K. M. (2015). Oral Transmucosal Detomidine Gel for the Sedation of the Domestic Ferret (Mustela putorius furo). Journal of Exotic Pet Medicine, 24(4), 446–454. https://doi.org/10.1053/j.jepm.2015.08.012

Chinnadurai, S. K., Messenger, K. M., Papich, M. G., & Harms, C. A. (2014). Meloxicam pharmacokinetics using nonlinear mixed-effects modeling in ferrets after single subcutaneous administration. Journal of Veterinary Pharmacology and Therapeutics, 37(4), 382–387. https://doi.org/10.1111/jvp.12099

Hutchins, R. G., Messenger, K. M., & Vaden, S. L. (2013). Suspected carprofen toxicosis caused by coprophagia in a dog. JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 243(5), 709–711. https://doi.org/10.2460/javma.243.5.709

Crook, K. I., Early, P. J., Messenger, K. M., Munana, K. R., Gallagher, R., & Papich, M. G. (2013). The pharmacokinetics of cytarabine in dogs when administered via subcutaneous and continuous intravenous infusion routes. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 36(4), 408–411. https://doi.org/10.1111/jvp.12008

Schwartz, M., Munana, K. R., Nettifee-Osborne, J. A., Messenger, K. M., & Papich, M. G. (2013). The pharmacokinetics of midazolam after intravenous, intramuscular, and rectal administration in healthy dogs. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 36(5), 471–477. https://doi.org/10.1111/jvp.12032

Hopfensperger, M. J., Messenger, K. M., Papich, M. G., & Sherman, B. L. (2013). The use of oral transmucosal detomidine hydrochloride gel to facilitate handling in dogs. JOURNAL OF VETERINARY BEHAVIOR-CLINICAL APPLICATIONS AND RESEARCH, 8(3), 114–123. https://doi.org/10.1016/j.jveb.2012.10.004

Da Cunha, A. F., Messenger, K. M., Stout, R. W., Barker, S. A., Nevarez, J. G., Queiroz-Williams, P., & Tully, T. N., Jr. (2012). Pharmacokinetics of lidocaine and its active metabolite monoethylglycinexylidide after a single intravenous administration in chickens (Gallus domesticus) anesthetized with isoflurane. JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 35(6), 604–607. https://doi.org/10.1111/j.1365-2885.2011.01358.x

Messenger, K. M., Papich, M. G., & Blikslager, A. T. (2011). Distribution of enrofloxacin and its active metabolite, using an in vivo ultrafiltration sampling technique after the injection of enrofloxacin to pigs. Journal of Veterinary Pharmacology and Therapeutics, 35(5), 452–459. https://doi.org/10.1111/j.1365-2885.2011.01338.x

Messenger, K. M., Davis, J. L., Lafevers, D. H., Barlow, B. M., & Posner, L. P. (2011). Intravenous and sublingual buprenorphine in horses: pharmacokinetics and influence of sampling site. Veterinary Anaesthesia and Analgesia.

Davis, J. L., Messenger, K. M., Lafevers, D. H., Barlow, B. M., & Posner, L. P. (2011). Pharmacokinetics of intravenous and intramuscular buprenorphine in the horse. Journal of Veterinary Pharmacology and Therapeutics, 35(1), 52–58. https://doi.org/10.1111/j.1365-2885.2011.01284.x