@article{halleran_yau_paegelow_streeter_foster_2021, title={Mycobacterial Cell Wall Stimulant in the Treatment of Squamous Cell Carcinoma: A Case Series Regarding Treatment in Equine, Bovine and Caprine Patients}, volume={8}, ISSN={["2297-1769"]}, DOI={10.3389/fvets.2021.635800}, abstractNote={Squamous cell carcinoma (SCC) is a common dermatological neoplasia found in large animal species. Treatment options, such as surgery and cryotherapy may be difficult or not feasible. Alternative therapies, such as immunomodulating drugs, can potentially be used for companion large animals. The hypothesis of the following retrospective study is: following multiple intravenous and intralesional injections of a mycobacterial cell wall stimulant (MCW) regression of SCC in equine, bovine and caprine patients will be observed. In this observational-retrospective case series, patients included are 2 bovine, 2 caprine and 3 equine patients. The medical records at two different teaching veterinary hospitals were searched for cases with a positive histopathological diagnosis of squamous cell carcinoma that were subsequently treated with MCW, as either the sole therapy, or in conjunction with other therapies. Seven cases were included in this retrospective study. The median duration of therapy was 56.5 days, with 3 of the 7 patients being euthanized. Significant complications were seen in 3/7 patients. Repeated injections of a MCW may lead to reduction in lesion size of SCC in some cases, but long-term resolution is unlikely and the risk of significant complications is high; due to limited sample size and the variety in species, it is difficult to conclude if MCW is an effective therapy for SCC.}, journal={FRONTIERS IN VETERINARY SCIENCE}, author={Halleran, Jennifer and Yau, Katie and Paegelow, Jillian and Streeter, Robert and Foster, Derek}, year={2021}, month={Aug} }
 @article{yau_halleran_boileau_foster_2021, title={Retrospective study on the use of lidocaine constant rate infusions for the treatment of ileus in ruminants and camelids}, volume={9}, ISSN={["1939-1676"]}, DOI={10.1111/jvim.16262}, abstractNote={AbstractLimited knowledge exists regarding the use of lidocaine as a prokinetic in ruminants and camelids to treat gastrointestinal ileus. In this retrospective study, ruminant and camelid cases diagnosed with ileus and treated with a lidocaine constant rate of infusion were assessed for adverse reactions and medical outcomes. A review of medical records was performed to identify cases in which lidocaine was administered as a prokinetic. Ten cases were identified consisting of 8 cattle, 1 goat, and 1 alpaca. Nine animals improved with a lidocaine treatment. No adverse effects were reported during lidocaine administration. Nine animals were discharged, and 1 was euthanized.}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Yau, Katie and Halleran, Jennifer and Boileau, Melanie and Foster, Derek}, year={2021}, month={Sep} }