Works (1)
Updated: July 5th, 2023 14:22
2021 journal article
Modeling the synergistic properties of drugs in hormonal treatment for prostate cancer
JOURNAL OF THEORETICAL BIOLOGY, 514.
author keywords: Prostate cancer modeling; Hormonal therapy; Intermittent androgen deprivation therapy; Adaptive therapy; Optimal treatment schedule; Drug effects; Androgen dynamics; Pharmacokinetics
MeSH headings : Androgen Antagonists / therapeutic use; Androgens; Antineoplastic Agents, Hormonal / therapeutic use; Humans; Male; Neoplasm Recurrence, Local; Pharmaceutical Preparations; Prostate-Specific Antigen; Prostatic Neoplasms / drug therapy
TL;DR:
This paper describes the first mathematical model that explicitly incorporates the synergistic effects of two drugs used to inhibit androgen production in hormonal therapy, and shows that the proposed model can capture the dynamics of serum androgen levels during intermittent hormonal therapy better than previously published models.
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UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: March 15, 2021
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