Kent R. Gordon

Works (1)

Updated: July 5th, 2023 15:40

2015 journal article

Magnetic Alignment of Microelements Containing Cultured Neuronal Networks for High-Throughput Screening

JOURNAL OF BIOMOLECULAR SCREENING, 20(9), 1091–1100.

By: K. Gordon n, Y. Wang *, N. Allbritton n & A. Taylor n

author keywords: high-throughput screening; primary neurons; magnetic centering; microfabrication; finite element analysis; microraft arrays
MeSH headings : Animals; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinical; High-Throughput Screening Assays / instrumentation; High-Throughput Screening Assays / methods; Magnetic Phenomena; Nerve Net / cytology; Neurons / drug effects; Neurons / physiology; Rats, Sprague-Dawley
TL;DR: A magnet array plate is developed, compatible with HTS fluid-handling systems, to center microrafts within wells, finding a centering efficiency of 100%, compared with 4.35% using a flat magnet, and concluding that micRORafts could be centered after settling randomly within the well, overcoming friction. (via Semantic Scholar)
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Added: August 6, 2018

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