Works (129)
Updated: August 16th, 2024 13:38
2024 article
Clinical and imaging findings in dogs with nerve root signature associated with cervical intervertebral disc herniation
Schachar, J., Bocage, A., Nelson, N. C., Early, P. J., Mariani, C. L., Olby, N. J., & Munana, K. R. (2024, January 12). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 1.
author keywords: cervical radiculopathy; intraforaminal disc herniation; magnetic resonance imaging; thoracic limb lameness
TL;DR:
NRS is most prevalent with C6‐C7 intervertebral disc involvement, suggesting that there might be unique anatomic factors that contribute to development of NRS at this site, but can be a clinical manifestation of IVDH occurring anywhere along the cervical spine.
(via Semantic Scholar)
open access via onlinelibrary.wiley.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 13, 2024
2024 article
Pharmacokinetics of subcutaneous ketamine administration via the Omnipod® system in dogs
Colon, C., Early, P., Munana, K., Olby, N., Mariani, C., Mancini, S., … Messenger, K. (2024, March 27). JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, Vol. 3.
author keywords: analgesia; canine; ketamine; novel; veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 8, 2024
2023 article
ACVIM Consensus Statement on the management of status epilepticus and cluster seizures in dogs and cats
Charalambous, M., Munana, K., Patterson, E. E., Platt, S. R., & Volk, H. A. (2023, November 3). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 11.
author keywords: cat; dog; emergency seizure disorders; treatment
TL;DR:
Successful management of seizure emergencies should include an early, rapid, and stage‐based treatment approach consisting of interventions with moderate to preferably high ACVIM recommendations; management of complications and underlying causes related to seizure emergencies should accompany antiseizure medications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 4, 2023
2023 journal article
Comparison of caregivers' assessments of clinical outcome in dogs with idiopathic epilepsy administered levetiracetam, zonisamide, or phenobarbital monotherapy
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 261(7), 1020–1027.
TL;DR:
Most caregivers reported a favorable outcome with administration of LEV, ZNS, or PB monotherapy to dogs with IE, and Phenobarbital is associated with the highest prevalence of AEs but no difference in quality of life score.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 23, 2023
2023 journal article
Effects of alfaxalone, propofol and isoflurane on cerebral blood flow and cerebrovascular reactivity to carbon dioxide in dogs: A pilot study
VETERINARY JOURNAL, 291.
author keywords: Alfaxalone; Cerebral blood flow; Intracranial pressure; Isoflurane; Propofol
MeSH headings : Dogs; Animals; Isoflurane / pharmacology; Propofol / pharmacology; Carbon Dioxide / pharmacology; Carbon Dioxide / physiology; Pilot Projects; Anesthetics, Inhalation / pharmacology; Cerebrovascular Circulation / physiology
TL;DR:
The hypothesis was that alfaxalone would not be significantly different to propofol, while isoflurane would increase cerebral blood flow and decrease cerebrovascular reactivity to CO2.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: January 23, 2023
2023 journal article
Magnetic resonance imaging characteristics of atlanto-axial subluxation in 42 dogs: Analysis of joint cavity size, subluxation distance, and craniocervical junction anomalies
OPEN VETERINARY JOURNAL, 13(9), 1091–1098.
author keywords: Canine; Cervical; Congenital; Malformation; Myelopathy
TL;DR:
Dogs with clinical signs of AA subluxation were significantly more likely to have intramedullary hyperintensity at the level of compression, an increased AA joint cavity size, and increased spinal cord compression at thelevel of dens and mid-body C2, according to MRI characteristics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 16, 2024
2023 article
Presumed pituitary apoplexy in 26 dogs: Clinical findings, treatments, and outcomes
Woelfel, C. W., Mariani, C. L., Nolan, M. W., Keenihan, E. K., Topulos, S. P., Early, P. J., … Olby, N. J. (2023, April 21). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 4.
author keywords: adenoma; carcinoma; endocrionopathy; hemorrhage; magnetic resonance imaging; suprasellar; survival
MeSH headings : Dogs; Animals; Pituitary Apoplexy / therapy; Pituitary Apoplexy / veterinary; Pituitary Apoplexy / diagnosis; Pituitary Neoplasms / complications; Pituitary Neoplasms / diagnostic imaging; Pituitary Neoplasms / therapy; Pituitary Neoplasms / veterinary; Retrospective Studies; Hydrocephalus / veterinary; Infarction / veterinary; Magnetic Resonance Imaging / veterinary; Dog Diseases / diagnostic imaging; Dog Diseases / therapy
TL;DR:
Dogs with pituitary apoplexy present with a variety of acute signs of neurological disease and inconsistent endocrine dysfunction and dogs that survive to discharge can have a favorable outcome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: April 22, 2023
2022 journal article
Novel subcutaneous cytarabine infusion with the Omnipod system in dogs with meningoencephalomyelitis of unknown etiology
AMERICAN JOURNAL OF VETERINARY RESEARCH, 83(9).
MeSH headings : Animals; Area Under Curve; Chromatography, High Pressure Liquid / veterinary; Cytarabine / therapeutic use; Dogs; Half-Life; Humans; Infusions, Intravenous / veterinary; North Carolina
TL;DR:
An SC continuous-rate infusion of cytarabine via the Omnipod system is feasible in dogs and was able to achieve a steady-state concentration of more than 1 μg/mL 4 to 10 hours postinitiation of cyTarabine and a Cmax of 7,510 ng/mL, comparable to values reported previously with IV continuous- rate infusion administration in healthy research Beagles and dogs with meningoencephalomyelitis of unknown etiology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 1, 2022
2021 journal article
Outcomes and prognostic indicators in 59 paraplegic medium to large breed dogs with extensive epidural hemorrhage secondary to thoracolumbar disc extrusion
VETERINARY SURGERY, 50(3), 527–536.
MeSH headings : Animals; Cohort Studies; Dog Diseases / diagnosis; Dog Diseases / surgery; Dogs; Female; Hematoma, Epidural, Spinal / complications; Hematoma, Epidural, Spinal / surgery; Hematoma, Epidural, Spinal / veterinary; Intervertebral Disc Degeneration / complications; Intervertebral Disc Degeneration / surgery; Intervertebral Disc Degeneration / veterinary; Laminectomy / statistics & numerical data; Laminectomy / veterinary; Male; Paraplegia / diagnosis; Paraplegia / surgery; Paraplegia / veterinary; Prognosis; Recovery of Function; Retrospective Studies; Species Specificity; Treatment Outcome; Walking
TL;DR:
Paraplegic medium to large breed dogs with DEEH have a less favorable outcome after surgical decompression than paraplegic dogs with TL-IVDE, and loss of pain perception and increased HASTEi are associated with a poor outcome, while more extensive decompression improves outcome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 8, 2021
2021 article
Understanding the impacts of feline epilepsy on cats and their owners
Henning, J., Nielson, T., Nettifee, J., Munana, K., & Hazel, S. (2021, August 23). VETERINARY RECORD, Vol. 8.
author keywords: burden of care; cat; cat owner relationship; feline epilepsy; human-animal interaction
MeSH headings : Animals; Cat Diseases / drug therapy; Cats; Emotions; Epilepsy / drug therapy; Epilepsy / veterinary; Quality of Life; Seizures / epidemiology; Seizures / veterinary; Surveys and Questionnaires
TL;DR:
Adequate seizure control and close cat-owner relationships may play an important role in mitigating the impact of epilepsy on cats and their owners.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 30, 2021
2021 article
Vascular endothelial growth factor concentrations in the cerebrospinal fluid of dogs with neoplastic or inflammatory central nervous system disorders
Mariani, C. L., Niman, Z. E., Boozer, L. B., Ruterbories, L. K., Early, P. J., Munana, K. R., & Olby, N. J. (2021, June 9). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 6.
author keywords: biomarker; brain tumor; meningoencephalitis; meningomyelitis
MeSH headings : Animals; Case-Control Studies; Central Nervous System Diseases / veterinary; Cerebrospinal Fluid; Dog Diseases; Dogs; Hospitals, Animal; Hospitals, Teaching; Vascular Endothelial Growth Factor A
TL;DR:
Concentrations of VEGF in CSF are higher in dogs with central nervous system (CNS) neoplasia compared to those with meningoencephalomyelitis and other neurologic disorders and may serve as a marker of neoplastic and inflammatory CNS disorders relative to other conditions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 10, 2021
2020 journal article
Association between anesthesia duration and outcome in dogs with surgically treated acute severe spinal cord injury caused by thoracolumbar intervertebral disk herniation
Journal of Veterinary Internal Medicine.
author keywords: canine; extrusion; hemilaminectomy; prognosis; surgery
MeSH headings : Anesthesia / adverse effects; Anesthesia / veterinary; Animals; Cohort Studies; Dog Diseases / surgery; Dogs; Female; Intervertebral Disc Degeneration / veterinary; Intervertebral Disc Displacement / veterinary; Laminectomy / veterinary; Male; Operative Time; Pain / veterinary; Paraplegia / rehabilitation; Paraplegia / surgery; Paraplegia / veterinary; Retrospective Studies; Spinal Cord Injuries / surgery; Spinal Cord Injuries / veterinary; Treatment Outcome; Walking
TL;DR:
A negative association between increased duration of anesthesia and outcome in dogs with absent pain perception treated surgically for acute thoracolumbar intervertebral disk herniation is supported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: ORCID, Crossref, NC State University Libraries
Added: May 18, 2020
2020 journal article
Cerebrospinal fluid lactate concentrations in dogs with seizure disorders
Journal of Veterinary Internal Medicine.
author keywords: acute repetitive seizures; biomarker; cluster seizures; epilepsy; status epilepticus
MeSH headings : Animals; Dog Diseases; Dogs; Epilepsy / veterinary; Humans; Lactic Acid; Seizures / veterinary; Status Epilepticus / veterinary
TL;DR:
Cerebrospinal fluid lactate concentration is minimally affected by seizure activity in dogs and increased concentrations are more likely associated with the underlying disease process.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: November 3, 2020
2020 journal article
Continuous rate infusion of midazolam as emergent treatment for seizures in dogs
Journal of Veterinary Internal Medicine.
author keywords: acute repetitive seizures; anticonvulsant; benzodiazepine; canine; cluster seizures; epilepsy; status epilepticus
MeSH headings : Animals; Anticonvulsants / adverse effects; Dog Diseases / drug therapy; Dogs; Hospitals, Animal; Hospitals, Teaching; Midazolam / therapeutic use; Retrospective Studies; Seizures / drug therapy; Seizures / veterinary
TL;DR:
Midazolam CRI is apparently safe and might be an effective treatment in dogs with CS or SE, and dogs with idiopathic/unknown epilepsy were more likely to survive than those with structural epilepsy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: December 17, 2020
2020 journal article
Evaluation of a collar‐mounted accelerometer for detecting seizure activity in dogs
Journal of Veterinary Internal Medicine, 34(3), 1239–1247.
author keywords: activity monitor; canine; clinical trial; idiopathic epilepsy
TL;DR:
Generalized seizures in dogs can be detected with a collar‐mounted accelerometer, but the overall sensitivity is low.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: April 16, 2020
2020 journal article
Evaluation of fecal Lactobacillus populations in dogs with idiopathic epilepsy: a pilot study
Animal Microbiome, 2(1).
author keywords: Seizures; Clinical study; Canine; Gut-brain-axis; Gut microbiota; Dysbiosis; Antiepileptic drugs
TL;DR:
Fecal Lactobacilli populations in dogs with idiopathic epilepsy compared to healthy dogs were evaluated and were not killed or inhibited from growing when exposed to phenobarbital, potassium bromide, zonisamide or levetiracetam, suggesting that antiepileptic drug administration is less likely to be a confounding factor in future studies evaluating the role of LactOBacillus in epilepsy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: May 12, 2020
2020 journal article
Influence of Duration of Injury on Diffusion Tensor Imaging in Acute Canine Spinal Cord Injury
JOURNAL OF NEUROTRAUMA, 37(21), 2261–2267.
author keywords: dog; fractional anisotropy; imaging biomarker; intervertebral disc herniation; mean diffusivity
MeSH headings : Animals; Diffusion Tensor Imaging / methods; Dogs; Intervertebral Disc Displacement / diagnostic imaging; Intervertebral Disc Displacement / pathology; Intervertebral Disc Displacement / veterinary; Spinal Cord Injuries / diagnostic imaging; Spinal Cord Injuries / pathology; Spinal Cord Injuries / veterinary; Time Factors
TL;DR:
Investigating the impact of duration of injury on DTI indices in dogs with acute, spontaneous SCI due to thoracolumbar intervertebral disc herniation and explore associations with clinical severity found MD might differentiate injury severity in the acute setting and be worthy of development as an imaging biomarker.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 31, 2020
2020 journal article
Traumatic skull fractures in dogs and cats: A comparative analysis of neurological and computed tomographic features
JOURNAL OF VETERINARY INTERNAL MEDICINE, 34(5), 1975–1985.
author keywords: canine; computed tomography; feline; skull fractures
MeSH headings : Animals; Cat Diseases / diagnostic imaging; Cats; Dog Diseases / diagnostic imaging; Dogs; Retrospective Studies; Skull / diagnostic imaging; Skull Fractures / diagnostic imaging; Skull Fractures / veterinary; Tomography, X-Ray Computed / veterinary
TL;DR:
The cranial vault fractures were associated with neurological deficits and worse survival, and the presence of TSF alone should not be considered a negative prognostic factor because most affected animals survived the first week.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 3, 2020
2019 journal article
Cerebrospinal fluid lactate in dogs with inflammatory central nervous system disorders
Journal of Veterinary Internal Medicine, 33(6), 2701–2708.
author keywords: canine; encephalitis; meningitis; meningo; meningoencephalitis; myelitis
MeSH headings : Animals; Dog Diseases / cerebrospinal fluid; Dogs; Inflammation / cerebrospinal fluid; Inflammation / veterinary; Lactic Acid / cerebrospinal fluid; Meningoencephalitis / cerebrospinal fluid; Meningoencephalitis / drug therapy; Meningoencephalitis / pathology; Meningoencephalitis / veterinary; Reference Values; Retrospective Studies; Steroids / therapeutic use
TL;DR:
Cerebrospinal fluid lactate concentrations could serve as a rapid biomarker of inflammatory CNS disease in dogs as well as humans with inflammatory central nervous system disorders.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 25, 2019
2019 journal article
Clinical characteristics, breed differences, and quality of life in North American dogs with acute steroid‐responsive meningitis‐arteritis
Journal of Veterinary Internal Medicine, 33(4), 1719–1727.
author keywords: aseptic meningitis; CSF analysis; immune-mediated disease; treatment response
MeSH headings : Animals; Arteritis / cerebrospinal fluid; Arteritis / drug therapy; Arteritis / veterinary; Canada / epidemiology; Dog Diseases / cerebrospinal fluid; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Female; Genetic Predisposition to Disease; Male; Meningitis / cerebrospinal fluid; Meningitis / drug therapy; Meningitis / veterinary; Neutrophils; Quality of Life; Recurrence; Retrospective Studies; Steroids / administration & dosage; Steroids / adverse effects; Steroids / therapeutic use; Surveys and Questionnaires; United States / epidemiology
TL;DR:
Golden Retrievers and Wirehaired Pointing Griffons should be considered among the breeds recognized to develop SRMA, and treatment with higher corticosteroid dosages is correlated with more severe adverse effects and worse QoL.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: June 8, 2019
2019 journal article
Comparison of cerebrospinal fluid parameters from the cerebellomedullary and lumbar cisterns in 54 dogs
Canadian Veterinary Journal, 60, 885–888.
Source: NC State University Libraries
Added: September 13, 2019
2019 journal article
Nutritional management of idiopathic epilepsy in dogs
Today’s Veterinary Practice.
Source: NC State University Libraries
Added: October 4, 2020
2019 journal article
Presence of cerebrospinal fluid antibodies associated with autoimmune encephalitis of humans in dogs with neurologic disease
Journal of Veterinary Internal Medicine, 33(5), 2175–2182.
author keywords: immunofluorescent assay; meningoencephalitis; MUE; NMDA receptor encephalitis
MeSH headings : Animals; Autoantibodies / cerebrospinal fluid; Central Nervous System Diseases / cerebrospinal fluid; Central Nervous System Diseases / immunology; Central Nervous System Diseases / veterinary; Dog Diseases / cerebrospinal fluid; Dog Diseases / immunology; Dogs; Female; Fluorescent Antibody Technique, Indirect / veterinary; Humans; Male; Meningoencephalitis / cerebrospinal fluid; Meningoencephalitis / immunology; Meningoencephalitis / therapy; Neurons / immunology; Receptors, N-Methyl-D-Aspartate / immunology
TL;DR:
Defining antigenic targets associated with encephalitis in dogs might allow diagnostic categorization of MUE antemortem and further evaluation of the prevalence and clinical relevance of CSF and serum antibodies to neuronal cell surface antigens is warranted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 9, 2019
2019 journal article
Risk factors associated with progressive myelomalacia in dogs with complete sensorimotor loss following intervertebral disc extrusion: a retrospective case-control study
BMC Veterinary Research, 15(1).
author keywords: Ascending-descending myelomalacia; Spinal cord injury; Intervertebral disk disease; Paraplegia
MeSH headings : Animals; Case-Control Studies; Dog Diseases / etiology; Dog Diseases / pathology; Dog Diseases / physiopathology; Dogs; Female; Intervertebral Disc Displacement / complications; Intervertebral Disc Displacement / veterinary; Logistic Models; Male; Multivariate Analysis; Paraplegia / etiology; Paraplegia / physiopathology; Paraplegia / veterinary; Retrospective Studies; Risk Factors; Spinal Cord Diseases / etiology; Spinal Cord Diseases / pathology; Spinal Cord Diseases / physiopathology; Spinal Cord Diseases / veterinary
TL;DR:
Dogs with lumbar intumescence IVDE are at increased risk of progressive myelomalacia and timing of surgery and corticosteroid use warrant further investigations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: February 10, 2020
2019 journal article
Time course and prognostic value of serum GFAP, pNFH, and S100β concentrations in dogs with complete spinal cord injury because of intervertebral disc extrusion
Journal of Veterinary Internal Medicine, 33(2), 726–734.
author keywords: biomarker; intervertebral disc disease; myelomalacia; prognosis
MeSH headings : Animals; Biomarkers / blood; Dogs / blood; Dogs / injuries; Glial Fibrillary Acidic Protein / blood; Intermediate Filaments / metabolism; Intervertebral Disc Degeneration / veterinary; Intervertebral Disc Displacement / veterinary; Paralysis / blood; Paralysis / veterinary; Phosphorylation; Prognosis; Prospective Studies; S100 Calcium Binding Protein beta Subunit / blood; Spinal Cord Injuries / blood; Time Factors
TL;DR:
Serum GFAP concentrations can be used to predict outcome in clinically complete SCI with an accuracy of 76.7%‐89% depending on sample timing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: February 20, 2019
2018 journal article
A randomized, blinded, prospective clinical trial of postoperative rehabilitation in dogs after surgical decompression of acute thoracolumbar intervertebral disc herniation
Journal of Veterinary Internal Medicine, 32(3), 1133–1144.
author keywords: ataxia; gait training; locomotion; plasticity; spinal cord injury
MeSH headings : Animals; Decompression, Surgical / methods; Decompression, Surgical / veterinary; Dog Diseases / surgery; Dogs; Female; Intervertebral Disc Displacement / rehabilitation; Intervertebral Disc Displacement / surgery; Intervertebral Disc Displacement / veterinary; Lumbar Vertebrae / surgery; Male; Postoperative Care / veterinary; Recovery of Function; Thoracic Vertebrae / surgery
TL;DR:
Early postoperative rehabilitation after surgery for TL‐IVDH is safe but doesn't improve rate or level of recovery in dogs with incomplete SCI.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2018 journal article
Population pharmacokinetics of extended-release levetiracetam in epileptic dogs when administered alone, with phenobarbital or zonisamide
Journal of Veterinary Internal Medicine, 32(5), 1677–1683.
author keywords: antiepileptic drug; canine; drug disposition; drug interactions; seizures
MeSH headings : Animals; Anticonvulsants / administration & dosage; Anticonvulsants / pharmacokinetics; Anticonvulsants / therapeutic use; Delayed-Action Preparations; Dog Diseases / blood; Dog Diseases / drug therapy; Dogs; Drug Interactions; Epilepsy / drug therapy; Epilepsy / veterinary; Levetiracetam / administration & dosage; Levetiracetam / pharmacokinetics; Levetiracetam / therapeutic use; Phenobarbital / administration & dosage; Phenobarbital / pharmacokinetics; Phenobarbital / therapeutic use; Zonisamide / administration & dosage; Zonisamide / pharmacokinetics; Zonisamide / therapeutic use
TL;DR:
Considerable variation exists in the pharmacokinetics of LEV‐XR in dogs with epilepsy being treated with a common dose regimen, and drug monitoring may be beneficial to determine the most appropriate dose of levetiracetam in individual dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: November 5, 2018
2018 journal article
The Effect of Electromagnetic Fields on Post-Operative Pain and Locomotor Recovery in Dogs with Acute, Severe Thoracolumbar Intervertebral Disc Extrusion: A Randomized Placebo-Controlled, Prospective Clinical Trial
Journal of Neurotrauma, 35(15), 1726–1736.
Contributors: N. Zidan n, J. Fenn *, E. Griffith n, P. Early n, C. Mariani n , n , J. Guevar n, N. Olby n
author keywords: biomarker; GFAP; hemilaminectomy; pain; spinal cord injury
MeSH headings : Animals; Decompression, Surgical; Dog Diseases / therapy; Dogs; Female; Intervertebral Disc Displacement / complications; Intervertebral Disc Displacement / surgery; Lumbar Vertebrae; Magnetic Field Therapy / methods; Male; Pain, Postoperative / etiology; Pain, Postoperative / therapy; Random Allocation; Recovery of Function / radiation effects; Spinal Cord Injuries / etiology; Spinal Cord Injuries / therapy; Thoracic Vertebrae
TL;DR:
It is concluded that PEMF reduced incision-associated pain in dogs post-surgery for IVDE and may reduce extent of SCI and enhance proprioceptive placing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2018 journal article
The pharmacokinetics of cytarabine administered subcutaneously, combined with prednisone, in dogs with meningoencephalomyelitis of unknown etiology
Journal of Veterinary Pharmacology & Therapeutics, 41(5), 638–643.
Contributors: B. Pastina n, P. Early n, R. Bergman*, J. Nettifee n , A. Maller*, K. Bray *, R. Waldron*, A. Castel *
author keywords: canine; cytarabine; MUE; Pharmacokinetics; sparse sampling; subcutaneous; canine; cytarabine; MUE; pharmacokinetics; sparse sampling; subcutaneous
MeSH headings : Animals; Antimetabolites, Antineoplastic / administration & dosage; Antimetabolites, Antineoplastic / blood; Antimetabolites, Antineoplastic / pharmacokinetics; Antimetabolites, Antineoplastic / therapeutic use; Cytarabine / administration & dosage; Cytarabine / blood; Cytarabine / pharmacokinetics; Cytarabine / therapeutic use; Dog Diseases / drug therapy; Dogs; Drug Combinations; Encephalomyelitis / drug therapy; Encephalomyelitis / veterinary; Female; Immunosuppressive Agents / administration & dosage; Immunosuppressive Agents / blood; Immunosuppressive Agents / pharmacokinetics; Immunosuppressive Agents / therapeutic use; Injections, Subcutaneous; Male; Meningoencephalitis / drug therapy; Meningoencephalitis / veterinary; Prednisone / administration & dosage; Prednisone / blood; Prednisone / pharmacokinetics; Prednisone / therapeutic use
TL;DR:
The pharmacokinetics of CA in dogs with MUE after a single 50 mg/m2 SC injection in dogs was similar to what has been previously reported in healthy beagles; there was moderate variability in the population estimates in this clinical population of dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 19, 2018
2017 journal article
Associations Between Anesthetic Variables and Functional Outcome in Dogs With Thoracolumbar Intervertebral Disk Extrusion Undergoing Decompressive Hemilaminectomy
Journal of Veterinary Internal Medicine, 31(3), 814–824.
Contributors: J. Fenn *, E. Laber n, K. Williams n, C. Rousse n, P. Early n, C. Mariani n , n , S. De Decker *, H. Volk *, N. Olby n
author keywords: Anesthesia; Canine; Intervertebral disk extrusion; Prognosis; Spinal cord injury
MeSH headings : Anesthesia, General / adverse effects; Anesthesia, General / methods; Anesthesia, General / veterinary; Animals; Bradycardia / chemically induced; Bradycardia / veterinary; Decompression, Surgical / methods; Decompression, Surgical / veterinary; Dog Diseases / surgery; Dogs; Female; Hypotension / chemically induced; Hypotension / veterinary; Intervertebral Disc Displacement / surgery; Intervertebral Disc Displacement / veterinary; Laminectomy / methods; Laminectomy / veterinary; Male; Retrospective Studies; Thoracic Vertebrae / surgery; Treatment Outcome
TL;DR:
Across all outcome measures, regression tree analysis highlighted functional grade at presentation as the primary determining factor, and among pain perception negative dogs, there was a possible association between increased duration of surgery and poorer outcome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2017 journal article
Clinical Characteristics of Dogs with Progressive Myelomalacia Following Acute Intervertebral Disc Extrusion
Journal of Veterinary Internal Medicine, 31(6), 1782–1789.
Contributors: A. Castel n, N. Olby n , C. Mariani n , n & P. Early n
author keywords: Ascending-descending myelomalacia; Intervertebral disc disease; Spinal cord injury
MeSH headings : Animals; Disease Progression; Dog Diseases / diagnostic imaging; Dog Diseases / pathology; Dogs; Female; Intervertebral Disc Degeneration / diagnostic imaging; Intervertebral Disc Degeneration / pathology; Intervertebral Disc Degeneration / veterinary; Intervertebral Disc Displacement / diagnostic imaging; Intervertebral Disc Displacement / pathology; Intervertebral Disc Displacement / veterinary; Magnetic Resonance Imaging / veterinary; Male; Myelography / veterinary; Retrospective Studies; Spinal Cord Diseases / mortality; Spinal Cord Diseases / pathology; Spinal Cord Diseases / veterinary; Tomography, X-Ray Computed / veterinary
TL;DR:
The majority of dogs developed PMM within 2 days of presentation and was euthanized within another 3 days, however, onset can be delayed up to 5 days after presentation with progression to euthanasia taking as long as 2 weeks.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2017 journal article
Evaluation of the Impacts of Epilepsy in Dogs on Their Caregivers
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 53(3), 143–149.
Contributors: J. Nettifee n, n & E. Griffith n
MeSH headings : Animals; Anticonvulsants / economics; Anticonvulsants / therapeutic use; Caregivers; Data Collection; Dog Diseases / drug therapy; Dog Diseases / economics; Dogs; Epilepsy / drug therapy; Epilepsy / economics; Epilepsy / veterinary; Humans; Quality of Life; Surveys and Questionnaires
TL;DR:
The majority of respondents reported positive scores for overallquality of life, although scores were significantly lower for dogs with poorly controlled epilepsy and medication-related adverse effects, and monthly medication cost was not associated with quality of life score.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2017 chapter
Seizures
In S. J. Ettinger, E. C. Feldman, & E. Cote (Eds.), Textbook of Veterinary Internal Medicine (8th ed., pp. 142–145). Elsevier.
Ed(s): S. Ettinger, E. Feldman & E. Cote
Source: NC State University Libraries
Added: October 4, 2020
2017 journal article
Using a modified bookmark procedure to help identify reasonable consequences for academic integrity violations
Journal of Veterinary Medical Education, 45(1), 43–50.
author keywords: academic affairs; assessment; curriculum; educational methods; outcomes; psychology; SKAs; student affairs
MeSH headings : Deception; Education, Veterinary / ethics; Education, Veterinary / standards; Educational Measurement / standards; Humans; Organizational Policy; Psychometrics / methods; Social Control, Formal
TL;DR:
A novel method is introduced for more objectively determining reasonable sanctions for several academic misconduct offenses of varying degrees of severity by utilizing a variation of the Bookmark procedure, a popular standard-setting technique used primarily by psychometricians in high-stakes testing environments.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
16. Peace, Justice and Strong Institutions
(OpenAlex)
Source: ORCID
Added: February 11, 2019
2016 journal article
2015 ACVIM Small Animal Consensus Statement on Seizure Management in Dogs
Journal of Veterinary Internal Medicine, 30(2), 477–490.
Contributors: M. Podell*, H. Volk *, M. Berendt *, W. Löscher *, n , E. Patterson*, S. Platt *
MeSH headings : Acupuncture Therapy / veterinary; Animals; Anticonvulsants / administration & dosage; Anticonvulsants / therapeutic use; Dog Diseases / therapy; Dogs; Epilepsy / therapy; Epilepsy / veterinary; Homeopathy; Practice Guidelines as Topic; Quality of Life; Vagus Nerve Stimulation / veterinary; Veterinary Medicine / standards
TL;DR:
The goal was to establish guidelines for a predetermined, concise, and logical sequential approach to chronic seizure management starting with seizure identification and diagnosis, and reviewing decision‐making, treatment strategies, and guidelines to enhance patient response and quality of life.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Clinical and Diagnostic Imaging Features of Brain Herniation in Dogs and Cats
Journal of Veterinary Internal Medicine, 30(5), 1672–1680.
MeSH headings : Animals; Body Size; Brain / diagnostic imaging; Brain / pathology; Cat Diseases / diagnostic imaging; Cat Diseases / pathology; Cats; Dog Diseases / diagnostic imaging; Dog Diseases / pathology; Dogs; Magnetic Resonance Imaging / veterinary; Retrospective Studies
TL;DR:
Brain herniation can be quantified on MRI and more severe CTH based on TTX is associated with a worse short‐term outcome, compared with more severe foramen magnum based on FMH.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: NC State University Libraries, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018
2016 journal article
Effect of Cranberry Extract on the Frequency of Bacteriuria in Dogs with Acute Thoracolumbar Disk Herniation: A Randomized Controlled Clinical Trial
Journal of Veterinary Internal Medicine, 31(1), 60–68.
Contributors: N. Olby n , S. Vaden n, K. Williams n, E. Griffith n, T. Harris n, C. Mariani n , n , P. Early n
author keywords: Escherichia coli; Incontinence; Proanthocyanidins; Spinal cord injury
MeSH headings : Administration, Oral; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / therapeutic use; Bacteriuria / complications; Bacteriuria / drug therapy; Bacteriuria / urine; Bacteriuria / veterinary; Dog Diseases / drug therapy; Dogs; Female; Intervertebral Disc Displacement / complications; Intervertebral Disc Displacement / veterinary; Male; Plant Extracts / administration & dosage; Plant Extracts / therapeutic use; Prospective Studies; Single-Blind Method; Thoracic Vertebrae; Treatment Outcome; Urinary Tract Infections / complications; Urinary Tract Infections / drug therapy; Urinary Tract Infections / urine; Urinary Tract Infections / veterinary; Vaccinium macrocarpon
TL;DR:
This clinical trial did not show a benefit of oral cranberry extract but had low power, but a possible association between urine AAA and lower risk of E. coli bacteriuria was identified.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2016 journal article
Eosinophilic meningomyelitis associated with T-cell lymphoma in a cat
VETERINARY CLINICAL PATHOLOGY, 45(4), 698–702.
Contributors: K. Bray n, n , K. Meichner n, L. White n & G. Seiler n
author keywords: Cerebrospinal fluid; eosinophilic pleocytosis; feline; neoplasia; tetraparesis
MeSH headings : Animals; CD3 Complex / immunology; Cat Diseases / cerebrospinal fluid; Cat Diseases / diagnostic imaging; Cat Diseases / pathology; Cats; Cervical Cord / diagnostic imaging; Cervical Cord / pathology; Eosinophils / pathology; Inflammation / veterinary; Leukocytosis / diagnosis; Leukocytosis / pathology; Leukocytosis / veterinary; Lymphoma, T-Cell / cerebrospinal fluid; Lymphoma, T-Cell / diagnostic imaging; Lymphoma, T-Cell / pathology; Lymphoma, T-Cell / veterinary; Magnetic Resonance Imaging / veterinary; Male
TL;DR:
Necropsy revealed an asymmetric infiltration predominantly of the white matter, meninges, and nerve roots of the C4-C6 spinal cord segments by an unencapsulated, poorly demarcated neoplasm composed of atypical lymphocytes admixed with eosinophils, causing perivascular hemorrhage and lytic necrosis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Epilepsy today - Summary of the consensus statements for definition, classification and terminology of epilepsy in companion animals as well as genetic origin in purebred dogs
Kleintier-Praxis, 61(8), 425–435.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Epilepsy today: Summary of the IVETF "Consensus Proposal: Medical treatment of canine epilepsy in Europe"
Kleintier-Praxis, 61(10), 529-.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Epilepsy today: Summary of the IVETF "Consensus proposal: Diagnostic Approach to Epilepsy in Dogs"
Kleintier-Praxis, 61(9), 477–487.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Plasma and serum concentrations of cytarabine administered via continuous intravenous infusion to dogs with meningoencephalomyelitis of unknown etiology
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 40(4), 411–414.
Contributors: P. Early n, K. Crook, L. Williams *, E. Davis *, n , M. Papich n , K. Messenger n
MeSH headings : Animals; Area Under Curve; Cytarabine / administration & dosage; Cytarabine / pharmacokinetics; Dog Diseases / blood; Dog Diseases / drug therapy; Dogs; Encephalomyelitis / blood; Encephalomyelitis / drug therapy; Encephalomyelitis / veterinary; Infusions, Intravenous / veterinary
TL;DR:
The steady-state achieved with cytarabine CRI produces a consistent and prolonged exposure in plasma and serum, which is likely to produce equilibrium between blood and the central nervous system in dogs with a clinical diagnosis of MUE.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
Prohibiting students from asking questions during exams: A guideline for promoting fairness and preserving score validity
Journal of Veterinary Medical Education, 44(2), 343–345.
author keywords: academic affairs; assessment; curriculum; disabilities; educational methods; SKAs; student affairs
MeSH headings : Behavior; Education, Veterinary; Educational Measurement / standards; Guidelines as Topic; Humans; North Carolina; Reproducibility of Results; Schools, Veterinary; Students, Medical
TL;DR:
The rationale behind policies that prohibit students from asking questions during examinations are presented and why these policies may help promote fairness and preserve score validity are discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
Source: ORCID
Added: February 11, 2019
2016 journal article
Recovery of stepping and coordination in dogs following acute thoracolumbar intervertebral disc herniations
The Veterinary Journal, 213, 59–63.
Contributors: C. Rousse n, N. Olby n , K. Williams n, T. Harris n, E. Griffith n, C. Mariani n , n , P. Early n
author keywords: Canine; Gait; Locomotion; Paralysis; Spinal cord injury
MeSH headings : Acute Disease; Animals; Dog Diseases / etiology; Dog Diseases / surgery; Dogs; Female; Forelimb / physiology; Hindlimb / physiology; Intervertebral Disc / pathology; Intervertebral Disc / surgery; Intervertebral Disc Displacement / etiology; Intervertebral Disc Displacement / surgery; Intervertebral Disc Displacement / veterinary; Male; Prospective Studies; Spinal Cord Injuries / etiology; Spinal Cord Injuries / surgery; Spinal Cord Injuries / veterinary; Walking
TL;DR:
Recovery of coordination was incomplete in dogs that showed good recovery of stepping in the 6 weeks following surgical decompression of dogs with TL-IVDH.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
A Placebo-Controlled, Prospective, Randomized Clinical Trial of Polyethylene Glycol and Methylprednisolone Sodium Succinate in Dogs with Intervertebral Disk Herniation
JOURNAL OF VETERINARY INTERNAL MEDICINE, 30(1), 206–214.
Contributors: N. Olby n , A. Muguet-Chanoit n, J. Lim n, M. Davidian n , C. Mariani n , A. Freeman*, S. Platt *, J. Humphrey n
author keywords: Neuroprotection; Paraplegia; Secondary injury; Spinal cord injury
MeSH headings : Animals; Anti-Inflammatory Agents / administration & dosage; Anti-Inflammatory Agents / therapeutic use; Dog Diseases / drug therapy; Dogs; Female; Intervertebral Disc Displacement / drug therapy; Intervertebral Disc Displacement / veterinary; Male; Methylprednisolone Hemisuccinate / administration & dosage; Methylprednisolone Hemisuccinate / therapeutic use; Nociception / drug effects; Polyethylene Glycols / administration & dosage; Polyethylene Glycols / therapeutic use
TL;DR:
This clinical trial did not show a benefit of either MPSS or PEG in the treatment of acute, severe thoracolumbar IVDH when used as adjunctive medical treatment administered to dogs presenting within 24 hours of onset of paralysis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 book review
Book review: Seizures in Dogs and Cats
[Review of Seizures in Dogs and Cats, by S. Sanders]. Journal of the American Veterinary Medical Association, 247, 619–620.
Source: NC State University Libraries
Added: March 4, 2021
2015 journal article
Effect of Chronic Administration of Phenobarbital, or Bromide, on Pharmacokinetics of Levetiracetam in Dogs with Epilepsy
JOURNAL OF VETERINARY INTERNAL MEDICINE, 29(2), 614–619.
Contributors: n , J. Nettifee-Osborne n & M. Papich n
author keywords: Antiepileptic drug; Canine; Drug disposition; Drug interactions; Seizures
MeSH headings : Animals; Anticonvulsants / administration & dosage; Anticonvulsants / pharmacokinetics; Anticonvulsants / therapeutic use; Area Under Curve; Bromides / administration & dosage; Bromides / therapeutic use; Dog Diseases / blood; Dog Diseases / drug therapy; Dog Diseases / metabolism; Dogs; Epilepsy / blood; Epilepsy / drug therapy; Epilepsy / veterinary; Half-Life; Levetiracetam; Phenobarbital / administration & dosage; Phenobarbital / therapeutic use; Piracetam / administration & dosage; Piracetam / analogs & derivatives; Piracetam / pharmacokinetics; Piracetam / therapeutic use
TL;DR:
Significant Dosage increases might be indicated when utilizing LEV as add‐on treatment with phenobarbital in dogs when administered concurrently with conventional AEDs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 chapter
Feline Hyperesthesia Syndrome
In L. P. Tilley & F. W. K. Smith (Eds.), Blackwell's 5-Minute Veterinary Consult, Canine and Feline (6th ed., p. 497). Wiley-Blackwell.
Ed(s): L. Tilley & F. Smith
Source: NC State University Libraries
Added: October 4, 2020
2015 journal article
International Veterinary Epilepsy Task Force consensus proposal: medical treatment of canine epilepsy in Europe
BMC Veterinary Research, 11(1).
Contributors: S. Bhatti *, L. De Risio *, n , J. Penderis, V. Stein *, A. Tipold *, M. Berendt *, R. Farquhar*
author keywords: Dog; Epileptic seizure; Epilepsy; Treatment
MeSH headings : Animals; Anticonvulsants / adverse effects; Anticonvulsants / therapeutic use; Dog Diseases / drug therapy; Dog Diseases / epidemiology; Dogs; Epilepsy / drug therapy; Epilepsy / epidemiology; Epilepsy / veterinary; Europe / epidemiology; Internationality; Practice Guidelines as Topic; Veterinary Medicine / organization & administration; Veterinary Medicine / standards
TL;DR:
This consensus proposal for drug treatment protocols is based on current published evidence-based literature, considers the current legal framework of the cascade regulation for the prescription of veterinary drugs in Europe, and reflects the authors’ experience.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
International Veterinary Epilepsy Task Force recommendations for a veterinary epilepsy-specific MRI protocol
BMC Veterinary Research, 11(1).
Contributors: C. Rusbridge, S. Long *, J. Jovanovik, M. Milne *, M. Berendt *, S. Bhatti*, L. De Risio *, R. Farqhuar*
author keywords: Canine; Feline; Seizure; Imaging; Hippocampus
MeSH headings : Animals; Brain / diagnostic imaging; Brain / pathology; Dog Diseases / diagnosis; Dog Diseases / pathology; Dogs; Epilepsy / diagnosis; Epilepsy / pathology; Epilepsy / veterinary; Internationality; Magnetic Resonance Imaging / methods; Magnetic Resonance Imaging / veterinary; Radiography; Veterinary Medicine / organization & administration
TL;DR:
There is a need for a standardized veterinary epilepsy-specific MRI protocol which will facilitate more detailed examination of areas susceptible to generating and perpetuating seizures, is cost efficient, simple to perform and can be adapted for both low and high field scanners.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
International veterinary epilepsy task force consensus proposal: diagnostic approach to epilepsy in dogs
BMC VETERINARY RESEARCH, 11(1).
Contributors: L. De Risio *, S. Bhatti *, n , J. Penderis, V. Stein *, A. Tipold *, M. Berendt *, R. Farqhuar*
author keywords: Dog; Seizure; Epilepsy; Idiopathic epilepsy; Diagnosis
MeSH headings : Animals; Dog Diseases / diagnosis; Dogs; Epilepsy / diagnosis; Epilepsy / veterinary; Genetic Predisposition to Disease; Internationality; Practice Guidelines as Topic; Veterinary Medicine / organization & administration
TL;DR:
This consensus article represents the basis for a more standardised diagnostic approach to the seizure patient and will evolve over time with advances in neuroimaging, electroencephalography, and molecular genetics of canine epilepsy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
International veterinary epilepsy task force consensus proposal: outcome of therapeutic interventions in canine and feline epilepsy
BMC Veterinary Research, 11(1).
Contributors: H. Potschka *, A. Fischer *, W. Löscher *, N. Patterson*, S. Bhatti *, M. Berendt *, L. De Risio *, R. Farquhar*
author keywords: Dog; Epileptic seizure; Epilepsy; Treatment
MeSH headings : Animals; Anticonvulsants / therapeutic use; Cat Diseases / drug therapy; Cats; Dog Diseases / drug therapy; Dogs; Internationality; Treatment Outcome; Veterinary Medicine / organization & administration
TL;DR:
The definition of drug resistance and partial therapeutic success in canine patients with epilepsy is provided and a list of factors and aspects of outcome, which should be considered in addition to the impact on seizures, are suggested.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
10. Reduced Inequalities
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
International veterinary epilepsy task force consensus report on epilepsy definition, classification and terminology in companion animals
BMC Veterinary Research, 11(1).
Contributors: M. Berendt *, R. Farquhar*, P. Mandigers *, A. Pakozdy*, S. Bhatti *, L. De Risio *, A. Fischer *, S. Long *
author keywords: Epilepsy; Seizures; Dog; Classification; Semiology
MeSH headings : Animals; Dog Diseases / classification; Dog Diseases / diagnosis; Dogs; Epilepsy / classification; Epilepsy / diagnosis; Epilepsy / veterinary; Internationality; Pets; Terminology as Topic; Veterinary Medicine / organization & administration
TL;DR:
The International Veterinary Epilepsy Task Force (IVETF) discusses current understanding of canine epilepsy and presents the 2015 proposal for terminology and classification of epilepsy and epileptic seizures, which reflects new thoughts from the human ILAE but also roots in former well accepted terminology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
International veterinary epilepsy task force recommendations for systematic sampling and processing of brains from epileptic dogs and cats
BMC Veterinary Research, 11(1).
Contributors: K. Matiasek *, M. Batlle, M. Rosati *, F. Fernández-Flores, A. Fischer *, E. Wagner *, M. Berendt *, S. Bhatti *
author keywords: Canine; Feline; Seizures; Hippocampus; Ictogenic; Epileptogenic; Processing; Neuropathology
MeSH headings : Animals; Brain / pathology; Cat Diseases / pathology; Cats; Dog Diseases / pathology; Dogs; Epilepsy / pathology; Epilepsy / veterinary; Specimen Handling / veterinary
TL;DR:
Brain dissection protocols of two neuropathological centres with research focus in epilepsy have been optimised with regards to their diagnostic yield and accuracy, their practicability and their feasibility concerning clinical research requirements.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2015 chapter
Nystagmus
In L. P. Tilley & F. W. K. Smith (Eds.), Blackwell's 5-Minute Veterinary Consult, Canine and Feline (6th ed., pp. 957–958). Wiley-Blackwell.
Ed(s): L. Tilley & F. Smith
Source: NC State University Libraries
Added: October 4, 2020
2013 journal article
Assessment of the prevalence and clinical features of cryptogenic epilepsy in dogs: 45 cases (2003-2011)
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 242(5), 651–657.
Contributors: M. Schwartz n, n & J. Nettifee-Osborne n
MeSH headings : Animals; Dog Diseases / diagnosis; Dogs; Epilepsy / diagnosis; Epilepsy / veterinary; Female; Longevity; Male; Retrospective Studies
TL;DR:
Cryptogenic epilepsy was diagnosed in a substantial proportion of dogs with an onset of epileptic seizures at ≥ 7 years of age and was considered acceptable in most dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2013 chapter
Head tilt and nystagmus
In BSAVA Manual of Canine and Feline Neurology (pp. 195–212).
TL;DR:
This chapter looks at clinical signs, lesion localization, pathophysiology, differential diagnosis, neurodiagnostic investigation, peripheral vestibular diseases, central vestIBular diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: November 16, 2019
2013 review
Management of Refractory Epilepsy
[Review of ]. TOPICS IN COMPANION ANIMAL MEDICINE, 28(2), 67–71.
author keywords: seizures; pharmacoresistance; antiepileptic drug; alternative therapy; vagal nerve stimulation; diet
MeSH headings : Animals; Anticonvulsants / adverse effects; Anticonvulsants / therapeutic use; Cat Diseases / drug therapy; Cats; Dog Diseases / drug therapy; Dogs; Epilepsy / drug therapy; Epilepsy / veterinary
TL;DR:
The 2 alternative forms of therapy that have shown the most promise in humans with epilepsy are electrical stimulation of the brain and dietary modification, both of which have also been evaluated in dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2013 journal article
Update Seizure Management in Small Animal Practice
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE, 43(5), 1127-+.
author keywords: Epilepsy; Antiepileptic drug; Pharmacology; Dog; Cat
MeSH headings : Algorithms; Animals; Anticonvulsants / therapeutic use; Cat Diseases / drug therapy; Cats; Dog Diseases / drug therapy; Dogs; Epilepsy / drug therapy; Epilepsy / veterinary; Seizures / drug therapy; Seizures / veterinary
TL;DR:
Recommendations for emergency care of seizures at home should be provided for patients with seizures that are not controlled with maintenance antiepileptic therapy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
Association between ABCB1 Genotype and Seizure Outcome in Collies with Epilepsy
Journal of Veterinary Internal Medicine, 26(6), 1358–1364.
Contributors: n , J. Nettifee-Osborne n, R. Bergman n & K. Mealey *
author keywords: Antiepileptic drug; Canine; Drug resistance; MDR1; P-glycoprotein
MeSH headings : ATP Binding Cassette Transporter, Subfamily B, Member 1 / genetics; Animals; Anticonvulsants / therapeutic use; Bromides / therapeutic use; Dog Diseases / drug therapy; Dog Diseases / genetics; Dogs; Epilepsy / drug therapy; Epilepsy / genetics; Epilepsy / veterinary; Gene Expression Regulation; Genetic Predisposition to Disease; Genotype; Phenobarbital / therapeutic use
TL;DR:
ABCB1 genotype is associated with seizure outcome in Collies with epilepsy, but this cannot be attributed to differences in PGP function, but might be because of intrinsic variations in seizure severity among phenotypes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: February 20, 2019
2012 journal article
Evaluation of Levetiracetam as Adjunctive Treatment for Refractory Canine Epilepsy: A Randomized, Placebo-Controlled, Crossover Trial
JOURNAL OF VETERINARY INTERNAL MEDICINE, 26(2), 341–348.
Contributors: n , W. Thomas*, K. Inzana*, J. Nettifee-Osborne n, K. McLucas*, N. Olby n , C. Mariani n , P. Early n
author keywords: Clinical pharmacology; CNS disorders; Dog; Epilepsy; Neurology; Seizures
MeSH headings : Animals; Anticonvulsants / administration & dosage; Anticonvulsants / adverse effects; Anticonvulsants / blood; Cross-Over Studies; Dog Diseases / blood; Dog Diseases / drug therapy; Dogs; Double-Blind Method; Epilepsy / blood; Epilepsy / drug therapy; Epilepsy / veterinary; Female; Levetiracetam; Male; Piracetam / administration & dosage; Piracetam / adverse effects; Piracetam / analogs & derivatives; Piracetam / blood; Quality of Life; Seizures / blood; Seizures / drug therapy; Seizures / veterinary; Statistics, Nonparametric
TL;DR:
Adjunctive treatment with LEV appears safe in epileptic dogs and effectiveness over placebo was not demonstrated, although the power of the study was limited.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
The pharmacokinetics of cytarabine in dogs when administered via subcutaneous and continuous intravenous infusion routes
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 36(4), 408–411.
Contributors: K. Crook n, P. Early n, K. Messenger n, n , R. Gallagher n & M. Papich n
MeSH headings : Animals; Antimetabolites, Antineoplastic / administration & dosage; Antimetabolites, Antineoplastic / blood; Antimetabolites, Antineoplastic / pharmacokinetics; Area Under Curve; Cross-Over Studies; Cytarabine / administration & dosage; Cytarabine / blood; Cytarabine / pharmacokinetics; Dogs / blood; Dogs / metabolism; Half-Life; Infusions, Intravenous / veterinary; Injections, Subcutaneous / veterinary
TL;DR:
The steady state achieved with the cyTarabine CRI may produce a more prolonged exposure of cytarabine at cytotoxic levels in plasma compared to the concentrations after SC administration, as these are two routes of administration commonly employed in the treatment of meningitis of unknown etiology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2012 journal article
The pharmacokinetics of midazolam after intravenous, intramuscular, and rectal administration in healthy dogs
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 36(5), 471–477.
Contributors: M. Schwartz n, n , J. Nettifee-Osborne n, K. Messenger n & M. Papich n
MeSH headings : Administration, Rectal; Animals; Anticonvulsants / administration & dosage; Anticonvulsants / blood; Anticonvulsants / pharmacokinetics; Chromatography, High Pressure Liquid; Dogs; Female; Injections, Intramuscular / veterinary; Injections, Intravenous / veterinary; Male; Midazolam / administration & dosage; Midazolam / blood; Midazolam / pharmacokinetics
TL;DR:
It is suggested that IM midazolam might be useful in treating seizures in dogs when venous access is unavailable, but higher doses may be needed to account for intermediate bioavailability.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2011 chapter
Feline Hyperesthesia Syndrome
In L. P. Tilley & F. W. K. Smith (Eds.), Blackwell's 5-Minute Veterinary Consult, Canine and Feline (5th ed., p. 463). Wiley-Blackwell.
Ed(s): L. Tilley & F. Smith
Source: NC State University Libraries
Added: October 4, 2020
2011 chapter
Nystagmus
In L. P. Tilley & F. W. K. Smith (Eds.), Blackwell's 5-Minute Veterinary Consult, Canine and Feline (5th ed., pp. 897–898,). Wiley-Blackwell.
Ed(s): L. Tilley & F. Smith
Source: NC State University Libraries
Added: October 4, 2020
2011 journal article
Possible Drug-Induced Hepatopathy in a Dog Receiving Zonisamide Monotherapy for Treatment of Cryptogenic Epilepsy
JOURNAL OF VETERINARY MEDICAL SCIENCE, 73(11), 1505–1508.
Contributors: M. Schwartz n, n & N. Olby n
author keywords: antiepileptic drug; canine; idiosyncratic drug reaction; liver; seizure
MeSH headings : Animals; Anticonvulsants / adverse effects; Anticonvulsants / therapeutic use; Chemical and Drug Induced Liver Injury / diagnosis; Chemical and Drug Induced Liver Injury / veterinary; Dog Diseases / chemically induced; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dogs; Epilepsy / drug therapy; Epilepsy / veterinary; Female; Isoxazoles / adverse effects; Isoxazoles / therapeutic use; Zonisamide
TL;DR:
If signs of hepatotoxicity are recognised early and zonisamide is discontinued, complete recovery is possible and Veterinary practitioners and owners should be educated about the potential for an idiosyncratic drug reaction to Zonisamide.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2011 journal article
The Cutaneous Trunci Muscle Reflex: A Predictor of Recovery in Dogs with Acute Thoracolumbar Myelopathies Caused by Intervertebral Disc Extrusions
Veterinary Surgery, 41(2), 200–206.
Contributors: A. Muguet-Chanoit n, N. Olby n , J. Lim n, R. Gallagher, Z. Niman*, S. Dillard*, J. Campbell n, P. Early n
MeSH headings : Animals; Cohort Studies; Dog Diseases / physiopathology; Dogs; Female; Intervertebral Disc Degeneration / veterinary; Intervertebral Disc Displacement / veterinary; Male; Muscle, Skeletal / physiology; Muscular Diseases / physiopathology; Muscular Diseases / veterinary; Predictive Value of Tests; Reflex / physiology
TL;DR:
Postoperative changes of the caudal border of the CTM reflex are an early indicator of outcome in dogs with severe acute IVDE and cranial movement of theCTM reflex is significantly associated with improvement, but not associated with a long-term successful outcome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2010 journal article
Levetiracetam pharmacokinetics in healthy dogs following oral administration of single and multiple doses
AMERICAN JOURNAL OF VETERINARY RESEARCH, 71(3), 337–341.
Contributors: S. Moore n, * , M. Papich* & J. Nettifee-Osborne
MeSH headings : Administration, Oral; Animals; Anticonvulsants / administration & dosage; Anticonvulsants / blood; Anticonvulsants / pharmacokinetics; Area Under Curve; Chromatography, High Pressure Liquid; Dogs; Half-Life; Kinetics; Levetiracetam; Metabolic Clearance Rate; Piracetam / administration & dosage; Piracetam / analogs & derivatives; Piracetam / blood; Piracetam / pharmacokinetics
TL;DR:
Results indicated that the pharmacokinetics of LEV did not change appreciably after administration of multiple doses over 7 days, within the therapeutic range established for LEV in humans.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2010 journal article
Prevalence of urinary tract infection in dogs after surgery for thoracolumbar intervertebral disc extrusion
Journal of Veterinary Internal Medicine, 24(5), 1106–1111.
Contributors: N. Olby n , E. MacKillop, S. Cerda-Gonzalez *, S. Moore *, n , M. Grafinger*, J. Osborne, S. Vaden n
author keywords: Incontinence; Micturition; Spinal cord injury
MeSH headings : Animals; Dog Diseases / etiology; Dogs; Female; Intervertebral Disc Displacement / surgery; Intervertebral Disc Displacement / veterinary; Male; Risk Factors; Surgical Procedures, Operative / adverse effects; Surgical Procedures, Operative / veterinary; Urinary Tract Infections / etiology; Urinary Tract Infections / veterinary
TL;DR:
There is a high prevalence of UTIs, many of which are occult, in the 3 months after surgery for thoracolumbar IVDE, and these dogs should be routinely monitored for UTI with urine culture regardless of urinalysis results.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: ORCID, NC State University Libraries, Web Of Science, NC State University Libraries
Added: August 6, 2018
2010 journal article
The pharmacokinetics of levetiracetam in healthy dogs concurrently receiving phenobarbital
Journal of Veterinary Pharmacology and Therapeutics, 34(1), 31–34.
Contributors: S. Moore n, n , M. Papich n & J. Nettifee-Osborne n
MeSH headings : Absorption; Animals; Anticonvulsants / blood; Anticonvulsants / pharmacokinetics; Area Under Curve; Dogs / blood; Drug Interactions; Half-Life; Levetiracetam; Phenobarbital / pharmacokinetics; Piracetam / analogs & derivatives; Piracetam / blood; Piracetam / pharmacokinetics
TL;DR:
Conurrent PB administration significantly alters the pharmacokinetics of LEV in the dog, indicating that dosage adjustments might be necessary when the drug is administered with PB.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2009 chapter
Brainstem Auditory Evoked Response
In S. Vaden, J. Knoll, L. P. Tilley, & F. W. K. Smith Jr. (Eds.), Blackwell's Five-Minute Veterinary Consult: Laboratory Tests and Diagnostic Procedures: Canine and Feline (pp. 129–131). Blackwell Publishing.
Ed(s): S. Vaden, J. Knoll, L. Tilley & F. Smith
Source: NC State University Libraries
Added: October 4, 2020
2009 chapter
Cerebrospinal Fluid Tap
In S. Vaden, J. Knoll, L. P. Tilley, & F. W. K. Smith Jr. (Eds.), Blackwell's Five-Minute Veterinary Consult: Laboratory Tests and Diagnostic Procedures: Canine and Feline (pp. 168–171). Blackwell Publishing.
Ed(s): S. Vaden, J. Knoll, L. Tilley & F. Smith
Source: NC State University Libraries
Added: October 4, 2020
2009 chapter
Feline Hyperesthesia Syndrome
In L. P. Tilley, F. W. K. Smith, S. L. Vaden, & J. S. Knoll (Eds.), Blackwell's Five-Minute Veterinary Consult: Laboratory Tests and Diagnostic Procedures: Canine and Feline (4th ed., pp. 480–481). New York: Wiley.
Ed(s): L. Tilley, F. Smith, S. Vaden & J. Knoll
Source: NC State University Libraries
Added: October 4, 2020
2009 book review
Large Animal Neurology
[Review of Large Animal Neurology, by J. Mayhew]. Journal of the American Veterinary Medical Association, 235, 700.
Source: NC State University Libraries
Added: October 4, 2020
2009 journal article
Medical Management of Refractory Canine Epilepsy
Veterinary Medicine, 104, 342–347.
Source: NC State University Libraries
Added: July 11, 2019
2009 journal article
Newer options for medically managing refractory canine epilepsy
Veterinary Medicine, 104(7), 342–347. http://www.scopus.com/inward/record.url?eid=2-s2.0-77249153182&partnerID=MN8TOARS
Source: ORCID
Added: February 20, 2019
2009 chapter
Nystagmus
In L. P. Tilley, F. W. K. Smith, S. L. Vaden, & J. S. Knoll (Eds.), Blackwell's Five-Minute Veterinary Consult: Laboratory Tests and Diagnostic Procedures: Canine and Feline (4th ed., pp. 980–981). New York: Wiley.
Ed(s): L. Tilley, F. Smith, S. Vaden & J. Knoll
Source: NC State University Libraries
Added: March 4, 2021
2009 journal article
Pharmacogenetic association study of 30 genes with phenobarbital drug response in epileptic dogs
Pharmacogenetics and Genomics, 19(12), 911–922.
Contributors: E. Kennerly n, Y. Idaghdour*, N. Olby n , n & G. Gibson*
author keywords: canine epilepsy; drug response; epoxide hydrolase; GABRA2; KCNQ3; pharmacogenetics; phenobarbital; SCN2A2
MeSH headings : Animals; Anticonvulsants / metabolism; Anticonvulsants / therapeutic use; Case-Control Studies; Dog Diseases / drug therapy; Dogs; Drug Resistance; Epilepsy / drug therapy; Epilepsy / veterinary; Pharmacogenetics; Phenobarbital / metabolism; Phenobarbital / therapeutic use; Polymorphism, Single Nucleotide
TL;DR:
Further replication and assessment of breed specificity is required before these markers can be considered as predictive of responsiveness to phenobarbital in dogs, but on functional grounds may tag strong candidate genes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2009 journal article
Placebo Effect in Canine Epilepsy Trials
JOURNAL OF VETERINARY INTERNAL MEDICINE, 24(1), 166–170.
Contributors: n , D. Zhang n & E. Patterson*
author keywords: Clinical trials; Dog; Epilepsy; Statistical modeling
MeSH headings : Animals; Anticonvulsants / therapeutic use; Bromides / therapeutic use; Diet / veterinary; Dog Diseases / diet therapy; Dog Diseases / drug therapy; Dogs; Epilepsy / diet therapy; Epilepsy / drug therapy; Epilepsy / veterinary; Linear Models; Phenobarbital / therapeutic use; Placebo Effect; Potassium Compounds / therapeutic use
TL;DR:
A positive response to placebo administration, manifesting as a decrease in seizure frequency, can be observed in epileptic dogs, of importance when evaluating open label studies in dogs that aim to assess efficacy of antiepileptic drugs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2007 journal article
Beta-2-microglobulin levels in the cerebrospinal fluid of normal dogs and dogs with neurological disease
VETERINARY CLINICAL PATHOLOGY, 36(2), 173–178.
Contributors: n , M. Saito n & F. Hoshi n
author keywords: beta-2-microglobulin; cerebrospinal fluid; dog; ELISA; inflammatory CNS disease
MeSH headings : Animals; Dog Diseases / cerebrospinal fluid; Dogs; Encephalitis / cerebrospinal fluid; Encephalitis / veterinary; Meningitis / cerebrospinal fluid; Meningitis / veterinary; Myelitis / cerebrospinal fluid; Myelitis / veterinary; Reference Values; beta 2-Microglobulin / cerebrospinal fluid
TL;DR:
CSF (beta2m concentration is higher in dogs with IVDD and inflammatory CNS disease, with highest values seen with inflammatory disease, may reflect intrathecal immune activation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2007 chapter
Brain, spinal cord, and nerve disorders
In Merck/Merial manual for pet health. Whitehouse Station, NJ : Merck & Co.
Source: NC State University Libraries
Added: August 6, 2018
2007 journal article
Imaging diagnosis-synchronous primary brain tumors in a dog
VETERINARY RADIOLOGY & ULTRASOUND, 48(6), 550–553.
Contributors: E. MacKillop n, D. Thrall n, R. Ranck n, K. Linder n & n
MeSH headings : Animals; Astrocytoma / pathology; Astrocytoma / veterinary; Cerebellar Neoplasms / pathology; Cerebellar Neoplasms / veterinary; Diagnosis, Differential; Dog Diseases / cerebrospinal fluid; Dog Diseases / pathology; Dogs; Magnetic Resonance Imaging / veterinary; Male; Medulloblastoma / pathology; Medulloblastoma / veterinary; Neoplasms, Multiple Primary / pathology; Neoplasms, Multiple Primary / veterinary; Thalamic Diseases / pathology; Thalamic Diseases / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
4. Quality Education
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2007 chapter
Meningitis and encephalitis in dogs, cats and horses
In The Merck-Merial Manual of Pet Health (pp. 210–211, 466–467, 722–723,).
Source: NC State University Libraries
Added: October 4, 2020
2007 article
Vertebral stabilization using positively threaded profile pins and polymethylmethacrylate, with or without laminectomy, for spinal canal stenosis and vertebral instability caused by congenital thoracic vertebral anomalies
Aikawa, T., Kanazono, S., Yoshigae, Y., Sharp, N. J. H., & Munana, K. R. (2007, July). VETERINARY SURGERY, Vol. 36, pp. 432–441.
Contributors: T. Aikawa n, S. Kanazono n, Y. Yoshigae n, N. Sharp n & n
MeSH headings : Animals; Bone Nails / veterinary; Constriction, Pathologic / veterinary; Decompression, Surgical / methods; Decompression, Surgical / veterinary; Dog Diseases / congenital; Dog Diseases / surgery; Dogs; Female; Laminectomy / methods; Laminectomy / veterinary; Male; Neurosurgical Procedures / methods; Neurosurgical Procedures / veterinary; Quality of Life; Retrospective Studies; Spinal Canal / surgery; Spinal Cord Diseases / surgery; Spinal Cord Diseases / veterinary; Spinal Fusion / methods; Spinal Fusion / veterinary; Surveys and Questionnaires; Thoracic Vertebrae / abnormalities; Thoracic Vertebrae / surgery; Treatment Outcome
TL;DR:
Vertebral stabilization using positively threaded profile pins and polymethylmethacrylate with or without laminectomy is an effective treatment for spinal canal stenosis and vertebral instability secondary to congenital thoracic vertebral anomalies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2006 journal article
Leading Edge - Management of refractory canine epilepsy
Veterinary Forum, 23, 42–46.
Source: NC State University Libraries
Added: July 28, 2019
2005 chapter
Meningitis and Encephalitis
In C. M. Kahn & S. Line (Eds.), Merck veterinary manual. Whitehouse Station, N.J. : Merck.
Ed(s): C. Kahn & S. Line
Source: NC State University Libraries
Added: August 6, 2018
2004 book review
Book review: Neurology for the Small Animal Practitioner
[Review of Neurology for the Small Animal Practitioner, by C. Chrisman, C. Mariani, & R. Clemmons]. Journal of the American Veterinary Medical Association, 224(6), 856.
Source: NC State University Libraries
Added: March 14, 2021
2004 journal article
Clinicopathological abnormalities and treatment response in 24 dogs seroreactive to Bartonella vinsonii (berkhoffii) antigens
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 40(2), 92–101.
Contributors: E. Breitschwerdt n , K. Blann n, M. Stebbins n, n , M. Davidson n, H. Jackson n, M. Willard n
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Antigens, Bacterial / cerebrospinal fluid; Antigens, Bacterial / immunology; Bartonella / immunology; Bartonella Infections / diagnosis; Bartonella Infections / drug therapy; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Diagnosis, Differential; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Female; Male; Retrospective Studies; Treatment Outcome
TL;DR:
It is indicated that a diverse spectrum of disease manifestations and clinicopathological abnormalities can be detected in dogs that are seroreactive to B. vinsonii (berkhoffii) antigens.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2004 chapter
Feline Hyperesthesia Syndrome
In L. P. Tilley & F. W. K. Smith (Eds.), The 5-minute veterinary consult : canine and feline (3rd ed., pp. 454–455). Baltimore, MD: Lippincott Williams & Wilkins.
Ed(s): L. Tilley & F. Smith
Source: NC State University Libraries
Added: March 14, 2021
2004 chapter
Head tilt and nystagmus
In S. R. Platt & N. J. Olby (Eds.), BSAVA Manual of Canine and Feline Neurology (3rd ed., pp. 155–171). British Small Animal Veterinary Association.
Ed(s): S. Platt & N. Olby
Source: NC State University Libraries
Added: October 4, 2020
2004 journal article
Lumbosacral disc disease in a cat
Veterinary and Comparative Orthopaedics and Traumatology, 17(2), 104–106.
TL;DR:
An eight-year-old male castrated domestic shorthair admitted with a two-day history of acute back pain, flaccid tail, and urinary and faecal incontinence is the first case report of a cat with documented lumbosacral disc disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2004 chapter
Nystagmus
In L. P. Tilley & F. W. K. Smith (Eds.), The 5-minute veterinary consult: canine and feline (3rd ed., pp. 924–925). Baltimore, MD: Lippincott Williams & Wilkins.
Ed(s): L. Tilley & F. Smith
Source: NC State University Libraries
Added: March 14, 2021
2004 journal article
Recovery of pelvic limb function in dogs following acute intervertebral disc herniations
JOURNAL OF NEUROTRAUMA, 21(1), 49–59.
author keywords: dog; disc herniation; functional recovery; spinal cord compression; spinal cord trauma
MeSH headings : Animals; Disease Models, Animal; Dogs; Hindlimb / physiopathology; Intervertebral Disc Displacement / complications; Intervertebral Disc Displacement / physiopathology; Lumbosacral Region / physiopathology; Pelvis / pathology; Recovery of Function; Spinal Cord Injuries / etiology; Spinal Cord Injuries / physiopathology; Thoracic Vertebrae / physiopathology
TL;DR:
It is concluded that dogs with spontaneous disc herniations provide a useful model of acute spinal cord injury for clinical trials and are suitable for use in clinical trials on neuroprotective drugs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2004 magazine article
Taking a practical approach to the management of seizures in dogs
DVM In Focus: A Supplement to DVM Newsmagazine, 21–24.
Source: NC State University Libraries
Added: March 14, 2021
2003 chapter
Disorders of the Brain
In R. Morgan (Ed.), Handbook of Small Animal Practice (4th ed., pp. 233–255). Philadelphia: WB Saunders.
Ed(s): R. Morgan
Source: NC State University Libraries
Added: October 4, 2020
2003 journal article
Long-term functional outcome of dogs with severe injuries of the thoracolumbar spinal cord: 87 cases (1996–2001)
Journal of the American Veterinary Medical Association, 222(6), 762–769.
MeSH headings : Age Factors; Animals; Body Weight; Dog Diseases / physiopathology; Dog Diseases / surgery; Dogs; Female; Intervertebral Disc Displacement / physiopathology; Intervertebral Disc Displacement / surgery; Intervertebral Disc Displacement / veterinary; Laminectomy / veterinary; Lumbar Vertebrae; Male; Pain / veterinary; Paraplegia / etiology; Paraplegia / surgery; Paraplegia / veterinary; Prognosis; Recovery of Function; Retrospective Studies; Spinal Cord Injuries / physiopathology; Spinal Cord Injuries / surgery; Spinal Cord Injuries / veterinary; Thoracic Vertebrae; Treatment Outcome
TL;DR:
Results suggested that the prognosis for paraplegic dogs without DPP because of trauma was guarded, while dogs with disk herniation had a better chance of recovering motor function.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2003 journal article
Relationship among basilar artery resistance index, degree of ventriculomegaly, and clinical signs in hydrocephalic dogs
VETERINARY RADIOLOGY & ULTRASOUND, 44(6), 687–694.
Contributors: M. Saito n, N. Olby n , K. Spaulding n, n & N. Sharp n
author keywords: hydrocephalus; resistance index; ventriculomegaly; ultrasound
MeSH headings : Animals; Basilar Artery / physiopathology; Blood Flow Velocity / veterinary; Cerebrovascular Circulation; Dog Diseases / diagnostic imaging; Dog Diseases / physiopathology; Dogs; Female; Hydrocephalus / physiopathology; Hydrocephalus / veterinary; Male; Predictive Value of Tests; Pulsatile Flow; Sensitivity and Specificity; Severity of Illness Index; Ultrasonography, Doppler, Transcranial / methods; Vascular Resistance
TL;DR:
The results suggest that ultrasonographic measurement of VB ratio and basilar artery RI may allow identification of dogs with symptomatic hydrocephalus or dogs that are at risk of developing symptomatic Hydrocephalus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2003 journal article
Spinal arachnoid cysts in 17 dogs
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 39(3), 271–282.
MeSH headings : Animals; Arachnoid Cysts / epidemiology; Arachnoid Cysts / veterinary; Cervical Vertebrae; Dog Diseases / diagnostic imaging; Dog Diseases / epidemiology; Dog Diseases / etiology; Dog Diseases / pathology; Dog Diseases / surgery; Dogs; Female; Magnetic Resonance Imaging / veterinary; Male; Myelography / veterinary; North Carolina / epidemiology; Records / veterinary; Retrospective Studies; Spinal Diseases / epidemiology; Spinal Diseases / veterinary; Spinal Fusion / veterinary; Thoracic Vertebrae
TL;DR:
The medical records of 17 dogs diagnosed with spinal arachnoid cysts at North Carolina State University Veterinary Teaching Hospital were retrospectively examined to identify trends in signalment, history, neurological status, treatment, and short- and long-term prognosis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2003 article
Use of a multiplex polymerase chain reaction assay in the antemortem diagnosis of toxoplasmosis and neosporosis in the central nervous system of cats and dogs
Schatzberg, S. J., Haley, N. J., Barr, S. C., deLahunta, A., Olby, N., Munana, K., & Sharp, N. J. H. (2003, December). AMERICAN JOURNAL OF VETERINARY RESEARCH, Vol. 64, pp. 1507–1513.
Contributors: S. Schatzberg*, N. Haley, S. Barr, A. deLahunta, N. Olby* , * , N. Sharp
MeSH headings : Animals; Cats; Central Nervous System / parasitology; Coccidiosis / diagnosis; Coccidiosis / veterinary; DNA Primers; Dogs; Electrophoresis, Agar Gel; Neospora / genetics; Polymerase Chain Reaction / methods; Sequence Analysis, DNA; Toxoplasma / genetics; Toxoplasmosis, Animal / diagnosis
TL;DR:
The multiplex PCR assay with built-in control reactions could be a complementary clinical tool for the antemortem diagnosis of toxoplasmosis or neosporosis associated with the CNS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2002 journal article
CT findings of intracranial blastomycosis in a dog
VETERINARY RADIOLOGY & ULTRASOUND, 43(1), 16–21.
Contributors: M. Saito*, N. Sharp, * , B. Troan *, M. Tokuriki n & D. Thrall n
MeSH headings : Animals; Blastomycosis / diagnostic imaging; Blastomycosis / pathology; Blastomycosis / veterinary; Dog Diseases / diagnostic imaging; Dog Diseases / pathology; Dogs; Male; Tomography, X-Ray Computed
TL;DR:
Computed tomography findings in a dog with intracranial blastomycosis were marked periventricular contrast enhancement of the lateral ventricles, the 3rd ventricle, and the mesencephalic aqueduct.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2002 journal article
Cervical injury following a horse kick to the head in two dogs
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 38(4), 321–326.
Contributors: N. Olby n , n , L. De Risio n, P. Sebestyen n & B. Hansen n
MeSH headings : Animals; Brain Injuries / complications; Brain Injuries / diagnostic imaging; Brain Injuries / pathology; Brain Injuries / therapy; Brain Injuries / veterinary; Cervical Vertebrae / injuries; Diagnosis, Differential; Dogs / injuries; Emergency Treatment / veterinary; Female; Horses; Magnetic Resonance Imaging / veterinary; Male; Radiography; Respiration, Artificial / veterinary; Spinal Injuries / complications; Spinal Injuries / diagnostic imaging; Spinal Injuries / pathology; Spinal Injuries / therapy; Spinal Injuries / veterinary; Wounds, Nonpenetrating / complications; Wounds, Nonpenetrating / diagnostic imaging; Wounds, Nonpenetrating / pathology; Wounds, Nonpenetrating / therapy; Wounds, Nonpenetrating / veterinary
TL;DR:
Two dogs were presented to North Carolina State University Veterinary Teaching Hospital following blunt trauma to the head delivered by a horse kick and both had compromise to their upper airway as a result of indirect injury to the soft tissues of the neck, visible on plain radiographs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2002 journal article
Dorsal laminectomy for caudal cervical spondylomyelopathy: Postoperative recovery and long-term follow-up in 20 dogs
Veterinary Surgery, 31(5), 418–427.
Contributors: L. De Risio n, n , M. Murray n, N. Olby n , N. Sharp n & P. Cuddon n
MeSH headings : Animals; Cervical Vertebrae / surgery; Colorado / epidemiology; Dog Diseases / mortality; Dog Diseases / surgery; Dogs; Female; Follow-Up Studies; Laminectomy / veterinary; Male; Neurologic Examination / veterinary; North Carolina / epidemiology; Postoperative Complications / veterinary; Records / veterinary; Recurrence; Retrospective Studies; Spinal Osteophytosis / mortality; Spinal Osteophytosis / surgery; Spinal Osteophytosis / veterinary; Treatment Outcome
TL;DR:
Dorsal cervical laminectomy is an effective treatment for CCSM in those dogs with dorsal compression or multiple sites of involvement and long-term outcome and recurrence rates were comparable to those seen with other surgical techniques for C CSM.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018
2002 article
Use of vagal nerve stimulation as a treatment for refractory epilepsy in dogs
Munana, K. R., Vitek, S. M., Tarver, W. B., Saito, M., Skeen, T. M., Sharp, N. J. H., … Haglund, M. M. (2002, October 1). JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 221, pp. 977–983.
Contributors: n , S. Vitek n, W. Tarver n, M. Saito n, T. Skeen n, N. Sharp n, N. Olby n , M. Haglund n
MeSH headings : Animals; Cross-Over Studies; Dog Diseases / therapy; Dogs; Electric Stimulation Therapy / adverse effects; Electric Stimulation Therapy / methods; Electric Stimulation Therapy / veterinary; Epilepsy / therapy; Epilepsy / veterinary; Female; Male; Pacemaker, Artificial / veterinary; Safety; Seizures / prevention & control; Seizures / veterinary; Treatment Outcome; Vagus Nerve / physiopathology
TL;DR:
Vagal nerve stimulation is a potentially safe approach to seizure control that appears to be efficacious in certain dogs and should be considered a possible treatment option when antiepileptic medications are ineffective.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2001 journal article
Development of a functional scoring system in dogs with acute spinal cord injuries
AMERICAN JOURNAL OF VETERINARY RESEARCH, 62(10), 1624–1628.
Contributors: N. Olby n , L. De Risio n, n , M. Wosar n, T. Skeen n, N. Sharp n, B. Keene n
MeSH headings : Animals; Dog Diseases / physiopathology; Dogs; Gait / physiology; Hindlimb / physiopathology; Intervertebral Disc Displacement / physiopathology; Intervertebral Disc Displacement / veterinary; Observer Variation; Paraplegia / etiology; Paraplegia / veterinary; Reproducibility of Results; Severity of Illness Index; Spinal Cord Diseases / complications; Spinal Cord Diseases / physiopathology; Spinal Cord Diseases / veterinary; Statistics, Nonparametric; Videotape Recording
TL;DR:
Pelvic limb gait of dogs recovering from thoracolumbar spinal cord injuries can be reliably quantified, using a numeric scale, and this scale will facilitate the performance of clinical trials aimed at improving the outcome of acute spinal Cord injuries.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2001 journal article
Infection of Fetal Feline Brain Cells in Culture with Bartonella henselae
Infection and Immunity, 69(1), 564–569.
Contributors: n , S. Vitek n, B. Hegarty n, D. Kordick n & E. Breitschwerdt n
MeSH headings : Animals; Astrocytes / microbiology; Bartonella henselae / physiology; Brain / cytology; Brain / microbiology; Brain Diseases / etiology; Cats; Cells, Cultured; DNA, Bacterial / analysis; Female; Fetus / microbiology; Microglia / microbiology; Microscopy, Electron; Pregnancy
TL;DR:
A role for microglia in the pathogenesis of B. henselae-associated neurological disease is suggested, and evidence of infection was seen in Bartonella-inoculated astrocyte cultures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
2001 chapter
Inflammatory Disorders of the Central Nervous System
In J. R. August (Ed.), Consultations in Feline Internal Medicine (4th ed., pp. 425–433). Philadelphia: WB Saunders.
Ed(s): J. August
Source: NC State University Libraries
Added: October 4, 2020
2001 journal article
Intervertebral disk disease in 10 cats
JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 37(4), 384–389.
MeSH headings : Animals; Cat Diseases / diagnostic imaging; Cat Diseases / epidemiology; Cat Diseases / pathology; Cats; Female; Intervertebral Disc; Lumbar Vertebrae; Male; North Carolina / epidemiology; Radiography; Records / veterinary; Retrospective Studies; Spinal Diseases / diagnostic imaging; Spinal Diseases / epidemiology; Spinal Diseases / pathology; Spinal Diseases / veterinary
TL;DR:
The medical records of 10 cats diagnosed with intervertebral disk disease were reviewed, and all cats judged to have an excellent outcome had undergone surgical decompression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2001 article
Predictors of outcome after dorsal decompressive laminectomy for degenerative lumbosacral stenosis in dogs: 69 cases (1987-1997)
De Risio, L., Sharp, N. J. H., Olby, N. J., Munana, K. R., & Thomas, W. B. (2001, September 1). JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 219, pp. 624–628.
Contributors: L. De Risio *, N. Sharp, N. Olby* , * & W. Thomas
MeSH headings : Animals; Decompression, Surgical / veterinary; Dog Diseases / surgery; Dogs; Female; Follow-Up Studies; Laminectomy / veterinary; Lumbosacral Region / surgery; Male; Medical Records; Prognosis; Retrospective Studies; Spinal Stenosis / complications; Spinal Stenosis / surgery; Spinal Stenosis / veterinary; Surveys and Questionnaires; Treatment Outcome; Urinary Incontinence / complications; Urinary Incontinence / veterinary
TL;DR:
Decompressive laminectomy is an effective treatment for DLSS, although dogs with urinary or fecal incontinence have a worse prognosis than dogs that are continent before surgery.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2001 journal article
Risk factors for development of status epilepticus in dogs with idiopathic epilepsy and effects of status epilepticus on outcome and survival time: 32 cases (1990-1996)
JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 219(5), 618–623.
Contributors: M. Saito n, n , N. Sharp n & N. Olby n
MeSH headings : Animals; Anticonvulsants / therapeutic use; Body Weight; Dog Diseases / diagnosis; Dog Diseases / etiology; Dog Diseases / mortality; Dogs; Epilepsy / complications; Epilepsy / mortality; Epilepsy / veterinary; Female; Male; Records / veterinary; Retrospective Studies; Risk Factors; Seizures / complications; Seizures / mortality; Seizures / veterinary; Status Epilepticus / etiology; Status Epilepticus / mortality; Status Epilepticus / veterinary; Treatment Outcome
TL;DR:
Results suggest that a substantial percentage of dogs with idiopathic epilepsy will have episodes of SE, and dogs with greater body weights were more likely to have episodes, and early appropriate seizure treatment did not appear to decrease the risk that dogs would have episodes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2000 journal article
Primary irradiation of canine intracranial masses
VETERINARY RADIOLOGY & ULTRASOUND, 41(4), 377–380.
Contributors: E. Spugnini n, D. Thrall n, G. Price n, N. Sharp n, n & R. Page n
author keywords: dog; brain tumor; radiation therapy
MeSH headings : Animals; Brain Neoplasms / diagnostic imaging; Brain Neoplasms / mortality; Brain Neoplasms / radiotherapy; Brain Neoplasms / veterinary; Dog Diseases / diagnostic imaging; Dog Diseases / mortality; Dog Diseases / radiotherapy; Dogs; Female; Glioma / diagnostic imaging; Glioma / mortality; Glioma / radiotherapy; Glioma / veterinary; Male; Meningeal Neoplasms / diagnostic imaging; Meningeal Neoplasms / mortality; Meningeal Neoplasms / radiotherapy; Meningeal Neoplasms / veterinary; Radiography; Radiotherapy / veterinary
TL;DR:
Radiation therapy is superior to medical treatment of brain tumors in dogs with steroids, is useful for tumors that are not currently operable and may be preferable to surgical resection in dogs if the mass appears infiltrative, however, 22/29 (76%) dogs died of recurrent progressive neuropathy suggestive of tumor regrowth or progression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2000 journal article
Spinal cord compression due to synovial cysts in a Great Dane
Kleintier-Praxis, 45(10), 787–792.
Source: NC State University Libraries
Added: August 6, 2018
2000 journal article
Spinal cord compression due to synovial cysts in a Great Dane,Rückenmarskompression durch Synoviazysten bei einer Deutschen Dogge
Kleintierpraxis, 45(10), 787–792. http://www.scopus.com/inward/record.url?eid=2-s2.0-0346385033&partnerID=MN8TOARS
Source: ORCID
Added: February 20, 2019
2000 journal article
The computed tomographic appearance of acute thoracolumbar intervertebral disk herniations in dogs.
Veterinary Radiology Ultrasound, 41(5), 396–402.
Contributors: N. Olby n , , N. Sharp n & D. Thrall n
author keywords: intervertebral disc herniation; computed tomography; myelography; epidural hemorrhage; dog
MeSH headings : Animals; Diskectomy; Dog Diseases / diagnostic imaging; Dog Diseases / surgery; Dogs; Hematoma, Epidural, Cranial / veterinary; Intervertebral Disc Displacement / diagnostic imaging; Intervertebral Disc Displacement / surgery; Intervertebral Disc Displacement / veterinary; Myelography; Spinal Cord / pathology; Tomography, X-Ray Computed
TL;DR:
In dogs with a long standing history of disc herniations, disc material identified in the vertebral canal had a more hyperattenuating and homogeneous appearance than recently herniated disc material.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
1999 journal article
Acute-Onset Vestibular Disease
Compendium’s Standards of Care, 1(8), 1–5.
Source: NC State University Libraries
Added: July 28, 2019
1999 journal article
Chronic and Acute Compressive Spinal Cord Lesions in Dogs due to Intervertebral Disc Herniation Are Associated With Elevation in Lumbar Cerebrospinal Fluid Glutamate Concentration
Journal of Neurotrauma, 16(12), 1215–1224.
author keywords: cerebrospinal fluid; dog; excitotoxicity; glutamate; spinal-cord compression; spinal cord injury
MeSH headings : Acute Disease; Animals; Chronic Disease; Dogs; Glutamic Acid / cerebrospinal fluid; Intervertebral Disc Displacement / complications; Lumbar Vertebrae; Lumbosacral Region; Osmolar Concentration; Reference Values; Spinal Cord Injuries / cerebrospinal fluid; Spinal Cord Injuries / etiology; Thoracic Vertebrae
TL;DR:
Dogs with chronic compressive thoracolumbar lesions have a two-fold elevation of CSF glutamate concentration, suggesting that excitotoxicity may also be a component of chronic spinal cord compression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018
1998 journal article
Evaluation of prognostic factors for canine granulomatous meningoencephalomyelitis: 42 cases (1982–1996)
Journal of the American Veterinary Medical Association, 212, 1902–1906.
Source: NC State University Libraries
Added: July 11, 2019
1998 journal article
Prognostic factors for dogs with granulomatous meningoencephalomyelitis: 42 Cases (1982-1996)
Journal of the American Veterinary Medical Association, 212(12), 1902–1906. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032525387&partnerID=MN8TOARS
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
1997 chapter
Disorders of the Brain
In R. Morgan (Ed.), Handbook of Small Animal Practice (3rd ed., pp. 230–251). Philadelphia: WB Saunders.
Ed(s): R. Morgan
Source: NC State University Libraries
Added: October 4, 2020
1997 journal article
Factor X deficiency in a cat
Journal of the American Veterinary Medical Association, 211(5), 576–579.
Source: NC State University Libraries
Added: August 6, 2018
1997 journal article
Factor X deficiency in a cat
Journal of the American Veterinary Medical Association, 211(5), 576–579. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031226017&partnerID=MN8TOARS
Source: ORCID
Added: February 20, 2019
1996 journal article
Encephalitis and meningitis
Veterinary Clinics of North America - Small Animal Practice, 26(4), 857–874. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030018463&partnerID=MN8TOARS
Source: ORCID
Added: February 20, 2019
1996 journal article
Feline ocular and cerebrospinal fluid Toxoplasma gondii-specific humoral immune responses following specific and nonspecific immune stimulation
Veterinary Immunology and Immunopathology, 55(1-3), 23–31.
Contributors: M. Lappin *, M. Chavkin*, * & C. Cooper*
author keywords: Toxoplasma gondii; toxoplasmosis; ocular; central nervous system; IgG; IgM; Goldman-Witmer coefficient
MeSH headings : Adjuvants, Immunologic / administration & dosage; Animals; Antibodies, Protozoan / biosynthesis; Antibodies, Protozoan / cerebrospinal fluid; Antibody Specificity; Antigens, Protozoan / administration & dosage; Antigens, Protozoan / immunology; Aqueous Humor / immunology; Cats; Immunization / veterinary; Toxoplasma / growth & development; Toxoplasma / immunology
TL;DR:
The results of this study suggest that T. gondii-specific IgG C values of over 1 in aqueous humor or CSF do not prove active ocular or central nervous system infection in all cats.
(via Semantic Scholar)
Source: ORCID
Added: February 20, 2019
1995 journal article
LONG-TERM COMPLICATIONS OF DIABETES-MELLITUS .1. RETINOPATHY, NEPHROPATHY, NEUROPATHY
VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE, 25(3), 715–730.
MeSH headings : Animals; Cat Diseases / etiology; Cats; Diabetes Complications; Diabetes Mellitus / veterinary; Diabetic Nephropathies / etiology; Diabetic Nephropathies / veterinary; Diabetic Neuropathies / etiology; Diabetic Neuropathies / veterinary; Diabetic Retinopathy / etiology; Diabetic Retinopathy / veterinary; Dog Diseases / etiology; Dogs; Time Factors
TL;DR:
The clinical and histopathologic findings seen with these late complications of diabetes are discussed, and current treatment consists of aggressive control of the hyperglycemia, as research continues into the pathology of the late complications in attempts to find a definitive therapy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
1995 journal article
Sequential measurement of Toxoplasma gondii-specific antibodies in the cerebrospinal fluid of cats with experimentally induced toxoplasmosis
Progress in Veterinary Neurology, 6, 27–31.
Source: NC State University Libraries
Added: July 28, 2019
1994 journal article
Canine clinical peripheral neuropathy associated with pancreatic islet cell carcinoma
Progress in Veterinary Neurology, 5, 57–62.
Source: NC State University Libraries
Added: October 4, 2020
1994 journal article
Neurological Manifestations of Niemann‐Pick Disease Type C in Cats
Journal of Veterinary Internal Medicine, 8(2), 117–121.
Contributors: * , P. Luttgen*, M. Thrall*, T. Mitchell * & D. Wenger *
MeSH headings : Animals; Cat Diseases / genetics; Cat Diseases / pathology; Cats; Cerebellum / pathology; Female; Liver / pathology; Male; Neurologic Examination / veterinary; Niemann-Pick Diseases / pathology; Niemann-Pick Diseases / veterinary; Pedigree
TL;DR:
Seven Domestic shorthair cats with a lysosomal storage disorder analogous to human Niemann-Pick disease type C, from a breeding colony were studied to characterize the neurological manifestations of this disorder.
(via Semantic Scholar)
Source: ORCID
Added: February 20, 2019
1994 journal article
Toxoplasma gondii-specific antibodies in the aqueous humor of cats with toxoplasmosis.
American Journal of Veterinary Research, 55(9), 1244–1249. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028507886&partnerID=MN8TOARS
Source: ORCID
Added: February 20, 2019
1991 journal article
Clinical Challenge: Case 2
Journal of Zoo and Wildlife Medicine, 22, 505–506.
Source: NC State University Libraries
Added: October 4, 2020
1991 journal article
What is your diagnosis?
Progress in Veterinary Neurology, 2, 213–214.
Source: NC State University Libraries
Added: October 4, 2020
Employment
Updated: August 10th, 2018 11:28
1994 - present
North Carolina State University Raleigh, NC, US
Professor, Neurology
Department of Clinical Sciences
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