Works (76)

Updated: August 21st, 2023 08:59

2023 journal article

A nanophotonic interferometer

NANOTECHNOLOGY, 34(18).

By: A. Ghaffari n, S. Kashani n, K. Do n, K. Weninger n & R. Riehn n

co-author countries: United States of America 🇺🇸
author keywords: zero mode waveguide; sub-wavelength aperture; interferometer
Sources: Web Of Science, ORCID
Added: January 19, 2023

2023 journal article

Ex vivo analysis of ultraviolet radiation transmission through ocular media and retina in select species

Experimental Eye Research, 233, 109550.

By: N. Himebaugh n, J. Robertson n, K. Weninger n, B. Gilger n, B. Ekesten* & A. Oh n

co-author countries: Sweden 🇸🇪 United States of America 🇺🇸
author keywords: Ultraviolet radiation; Ocular media; Canine; Feline; Human; Vision
Sources: Web Of Science, ORCID, Crossref
Added: June 25, 2023

2023 journal article

Frustration Between Preferred States of Complementary Trinucleotide Repeat DNA Hairpins Anticorrelates with Expansion Disease Propensity

JOURNAL OF MOLECULAR BIOLOGY, 435(10).

By: P. Xu n, J. Zhang n, F. Pan n, C. Mahn n, C. Roland n, C. Sagui n, K. Weninger n

co-author countries: United States of America 🇺🇸
author keywords: single molecule FRET; hairpin slippage; molecular dynamics; kinetics; trinucleotide interrupts; Huntington's disease
MeSH headings : Humans; DNA / genetics; DNA / chemistry; DNA, Complementary; Nucleic Acid Conformation; Trinucleotide Repeat Expansion / genetics; Trinucleotide Repeats; Neurodegenerative Diseases / genetics
Sources: Web Of Science, ORCID
Added: May 22, 2023

2023 review

Illuminating Intrinsically Disordered Proteins with Integrative Structural Biology

[Review of ]. BIOMOLECULES, 13(1).

By: R. Evans n, S. Ramisetty*, P. Kulkarni* & K. Weninger n

co-author countries: United States of America 🇺🇸
author keywords: intrinsically disordered proteins; integrative structural biology; unfolded; unstructured; flexible; protein function
MeSH headings : Intrinsically Disordered Proteins / chemistry; Signal Transduction; Biology; Protein Conformation
Sources: Web Of Science, ORCID
Added: February 13, 2023

2022 article

A Nanophotonic Interferometer for small particle detection

INTERFEROMETRY XXI, Vol. 12223.

By: A. Ghaffari, K. Do n, S. Kashani n, K. Weninger n & R. Riehn n

co-author countries: United States of America 🇺🇸
author keywords: zero mode waveguide; sub-wavelength aperture; interferometer
Sources: Web Of Science, ORCID
Added: November 7, 2022

2022 journal article

A blind benchmark of analysis tools to infer kinetic rate constants from single-molecule FRET trajectories

NATURE COMMUNICATIONS, 13(1).

co-author countries: Switzerland 🇨🇭 Germany 🇩🇪 Denmark 🇩🇰 France 🇫🇷 Netherlands 🇳🇱 United States of America 🇺🇸
MeSH headings : Benchmarking; Fluorescence Resonance Energy Transfer / methods; Kinetics; Models, Theoretical
Sources: Web Of Science, ORCID
Added: October 3, 2022

2022 article

Non-ergodicity of a globular protein extending beyond its functional timescale

Li, J., Xie, J. F., Godec, A., Weninger, K. R., Liu, C., Smith, J. C., & Hong, L. (2022, August 4). CHEMICAL SCIENCE, Vol. 8.

By: J. Li*, J. Xie*, A. Godec*, K. Weninger n, C. Liu*, J. Smith*, L. Hong*

co-author countries: China 🇨🇳 Germany 🇩🇪 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 22, 2022

2021 journal article

Integrative structural dynamics probing of the conformational heterogeneity in synaptosomal-associated protein 25

CELL REPORTS PHYSICAL SCIENCE, 2(11).

By: N. Saikia*, I. Yanez-Orozco*, R. Qiu n, P. Hao n, S. Milikisiyants n, E. Ou n, G. Hamilton*, K. Weninger n ...

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: March 14, 2022

2021 review

Molecular conformations and dynamics of nucleotide repeats associated with neurodegenerative diseases: double helices and CAG hairpin loops

[Review of ]. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 19, 2819–2832.

By: F. Pan*, Y. Zhang*, P. Xu n, V. Man n, C. Roland n, K. Weninger n, C. Sagui n

co-author countries: United States of America 🇺🇸
author keywords: Trinucleotide hexanucleotide repeats; CAG; GAC; CTG; CUG; CCG; GGC; GGGGCC; GGCCCC; Hairpin loops; smFRET; Molecular dynamics
Sources: Web Of Science, ORCID
Added: August 30, 2021

2021 journal article

Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA

JOURNAL OF BIOLOGICAL CHEMISTRY, 297(3).

By: H. Pan n, P. Kaur n, R. Barnes*, A. Detwiler*, S. Sanford*, M. Liu n, P. Xu n, C. Mahn n ...

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
MeSH headings : Cell Adhesion Molecules / metabolism; Cell Adhesion Molecules / physiology; DNA / metabolism; DNA-Binding Proteins / metabolism; Humans; Microscopy, Atomic Force / methods; Models, Molecular; Multiprotein Complexes / metabolism; Protein Binding; Protein Isoforms / metabolism; Shelterin Complex / metabolism; Shelterin Complex / physiology; Telomere / metabolism; Telomere-Binding Proteins / metabolism; Telomere-Binding Proteins / physiology; Telomeric Repeat Binding Protein 1 / metabolism; Telomeric Repeat Binding Protein 1 / physiology; Telomeric Repeat Binding Protein 2 / metabolism; Telomeric Repeat Binding Protein 2 / physiology
Sources: Web Of Science, ORCID
Added: October 26, 2021

2020 journal article

Dynamic human MutS alpha-MutL alpha complexes compact mismatched DNA

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117(28), 16302–16312.

By: K. Bradford*, H. Wilkins*, P. Hao n, Z. Li*, B. Wang*, D. Burke*, D. Wu*, A. Smith* ...

co-author countries: United States of America 🇺🇸
author keywords: DNA repair; AFM; MutS; MutL; DREEM
MeSH headings : Adenosine Triphosphate / metabolism; DNA / chemistry; DNA / genetics; DNA / metabolism; DNA Mismatch Repair; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / metabolism; Humans; Multiprotein Complexes / metabolism; MutL Proteins / chemistry; MutL Proteins / metabolism; MutS Homolog 2 Protein / chemistry; MutS Homolog 2 Protein / metabolism; Nucleic Acid Conformation; Nucleosomes / metabolism; Protein Folding; Protein Multimerization
Sources: Web Of Science, ORCID
Added: August 17, 2020

2020 journal article

Dynamics of strand slippage in DNA hairpins formed by CAG repeats: roles of sequence parity and trinucleotide interrupts

Nucleic Acids Research, 1.

By: P. Xu n, F. Pan n, C. Roland n, C. Sagui n & K. Weninger n

co-author countries: United States of America 🇺🇸
MeSH headings : Base Pairing; DNA / chemistry; Fluorescence Resonance Energy Transfer; Inverted Repeat Sequences; Kinetics; Molecular Dynamics Simulation; Nucleic Acid Conformation; Single Molecule Imaging; Thermodynamics; Trinucleotide Repeats
Source: ORCID
Added: September 2, 2021

2020 journal article

How Membrane Geometry Regulates Protein Sorting Independently of Mean Curvature

ACS CENTRAL SCIENCE, 6(7), 1159–1168.

By: J. Larsen*, K. Rosholm*, C. Kennard*, S. Pedersen*, H. Munch*, V. Tkach*, J. Sakon n, T. Bjornholm* ...

co-author countries: Denmark 🇩🇰 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 24, 2020

2020 journal article

Recurrent mismatch binding by MutS mobile clamps on DNA localizes repair complexes nearby

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117(30), 17775–17784.

By: P. Hao n, S. LeBlanc n, B. Case*, T. Elston*, M. Hingorani*, D. Erie*, K. Weninger n

co-author countries: United States of America 🇺🇸
author keywords: smFRET; MMR; mismatch repair; MutS
MeSH headings : Adenosine Triphosphatases / metabolism; Adenosine Triphosphate / metabolism; Base Pair Mismatch; DNA / chemistry; DNA / genetics; DNA / metabolism; DNA Mismatch Repair; Hydrolysis; Models, Molecular; Multiprotein Complexes / metabolism; MutL Proteins / chemistry; MutL Proteins / metabolism; MutS DNA Mismatch-Binding Protein / chemistry; MutS DNA Mismatch-Binding Protein / metabolism; Structure-Activity Relationship
Sources: Web Of Science, ORCID
Added: August 17, 2020

2019 journal article

Investigating the Function of Mutl Conformational Changes in Mismatch Repair using smFRET

Biophysical Journal, 116(3), 49a–50a.

By: S. LeBlanc*, P. Hao n, M. Hinds*, A. Morgan*, K. Gbozah*, K. Weninger n, D. Erie*

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2019 review

Spontaneous Switching among Conformational Ensembles in Intrinsically Disordered Proteins

[Review of ]. BIOMOLECULES, 9(3).

By: U. Choi*, H. Sanabria*, T. Smirnova n, M. Bowen* & K. Weninger n

co-author countries: United States of America 🇺🇸
author keywords: dynamic configuration; free energy landscape; intrinsically disordered protein; IDP
MeSH headings : Humans; Intrinsically Disordered Proteins / chemistry; Protein Conformation
Sources: Web Of Science, ORCID
Added: April 29, 2019

2019 journal article

Structural and Dynamical Order of a Disordered Protein: Molecular Insights into Conformational Switching of PAGE4 at the Systems Level

Biomolecules, 9(2), 77.

By: X. Lin*, P. Kulkarni*, F. Bocci*, N. Schafer*, S. Roy*, M. Tsai*, Y. He*, Y. Chen* ...

co-author countries: Canada 🇨🇦 China 🇨🇳 India 🇮🇳 Russian Federation 🇷🇺 Taiwan, Province of China 🇹🇼 United States of America 🇺🇸
author keywords: PAGE4; intrinsically disordered proteins; conformational plasticity; order-disorder transition; phosphorylation
MeSH headings : Antigens, Neoplasm / chemistry; Antigens, Neoplasm / metabolism; Humans; Intrinsically Disordered Proteins / chemistry; Intrinsically Disordered Proteins / metabolism; Molecular Dynamics Simulation; Protein Conformation
Sources: Web Of Science, ORCID, Crossref
Added: March 25, 2019

2019 journal article

TIN2 is an Architectural Protein Stabilizing TRF1 at Telomere

Biophysical Journal, 116(3), 211a–212a.

By: H. Pan n, S. Dangi n, P. Kaur n, P. Hao n, K. Weninger n, R. Riehn n, P. Opresko*, H. Wang n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: January 25, 2020

2019 journal article

Toward Single Molecule FRET Studies of DNA Mismatch Repair in Live Bacteria

Biophysical Journal, 116(3), 139a.

By: P. Xu n, A. Hensley n, E. Chan n & K. Weninger n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2019 journal article

Untangling DNA Mismatch Repair Complexes with smFRET and Tethered Particle Motion Analysis

Biophysical Journal, 116(3), 77a.

By: P. Hao n, S. LeBlanc, D. Erie & K. Weninger n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2018 journal article

Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS

NUCLEIC ACIDS RESEARCH, 46(20), 10782–10795.

By: S. LeBlanc n, J. Gauer*, P. Hao n, B. Case*, M. Hingorani*, K. Weninger n, D. Erie*

co-author countries: United States of America 🇺🇸
MeSH headings : Base Pair Mismatch / genetics; Base Pairing / physiology; DNA / chemistry; DNA Mismatch Repair / genetics; Escherichia coli; Fluorescence Resonance Energy Transfer; Genomic Instability / genetics; Models, Molecular; MutS DNA Mismatch-Binding Protein / chemistry; MutS DNA Mismatch-Binding Protein / genetics; MutS DNA Mismatch-Binding Protein / metabolism; Mutant Proteins / chemistry; Mutant Proteins / metabolism; Nucleic Acid Conformation; Protein Binding / physiology; Protein Conformation; Protein Domains / genetics; Protein Isoforms / chemistry; Protein Isoforms / genetics; Protein Isoforms / metabolism
Sources: Web Of Science, ORCID
Added: February 11, 2019

2018 journal article

Motor-like DNA motion due to an ATP-hydrolyzing protein under nanoconfinement

Scientific Reports, 8(1).

By: M. Roushan n, Z. Azad n, S. Movahed n, P. Ray n, G. Livshits n, S. Lim n, K. Weninger n, R. Riehn n

co-author countries: Japan 🇯🇵 United States of America 🇺🇸
MeSH headings : Adenosine Triphosphate / metabolism; DNA / metabolism; DNA Ligases / metabolism; DNA Ligases / physiology; DNA-Binding Proteins / genetics; Diffusion; Escherichia coli / genetics; Escherichia coli / metabolism; Escherichia coli Proteins / metabolism; Escherichia coli Proteins / physiology; Motion; MutS DNA Mismatch-Binding Protein / metabolism; MutS DNA Mismatch-Binding Protein / physiology; NAD / metabolism
Sources: Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2018 journal article

PAGE4 and Conformational Switching: Insights from Molecular Dynamics Simulations and Implications for Prostate Cancer

Journal of Molecular Biology, 430(16), 2422–2438.

By: X. Lin*, S. Roy*, M. Jolly*, F. Bocci*, N. Schafer*, M. Tsai*, Y. Chen*, Y. He* ...

co-author countries: India 🇮🇳 United States of America 🇺🇸

Contributors: X. Lin*, S. Roy*, M. Jolly*, F. Bocci*, N. Schafer*, M. Tsai*, Y. Chen*, Y. He* ...

author keywords: intrinsically disordered protein; PAGE4; AWSEM; order-disorder transition; non-genetic heterogeneity
MeSH headings : Antigens, Neoplasm / chemistry; Antigens, Neoplasm / metabolism; Fluorescence Resonance Energy Transfer; Humans; Male; Models, Molecular; Models, Theoretical; Molecular Dynamics Simulation; Phosphorylation; Prostatic Neoplasms / metabolism; Protein Conformation; Protein Serine-Threonine Kinases / metabolism; Protein-Tyrosine Kinases / metabolism; Receptors, Androgen / metabolism; Scattering, Small Angle; Signal Transduction; Single Molecule Imaging; Transcription Factor AP-1 / metabolism; X-Ray Diffraction
Sources: Crossref, ORCID
Added: February 5, 2020

2018 review

Phenotypic Plasticity, Bet-Hedging, and Androgen Independence in Prostate Cancer: Role of Non-Genetic Heterogeneity

[Review of ]. FRONTIERS IN ONCOLOGY, 8.

co-author countries: United States of America 🇺🇸
author keywords: bet-hedging; stochasticity; androgen independence; non-genetic heterogeneity; phenotypic plasticity; intermittent androgen therapy
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study

NATURE METHODS, 15(9), 669-+.

By: B. Hellenkamp*, S. Schmid*, O. Doroshenko*, O. Opanasyuk*, R. Kuehnemuth, S. Adariani*, B. Ambrose*, M. Aznauryan* ...

co-author countries: Belgium 🇧🇪 Switzerland 🇨🇭 Germany 🇩🇪 Denmark 🇩🇰 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Korea (Republic of) 🇰🇷 Netherlands 🇳🇱 United States of America 🇺🇸
MeSH headings : Fluorescence Resonance Energy Transfer / methods; Laboratories / standards; Reproducibility of Results
Sources: Web Of Science, ORCID
Added: October 19, 2018

2018 review

Prostate-Associated Gene 4 (PAGE4): Leveraging the Conformational Dynamics of a Dancing Protein Cloud as a Therapeutic Target

[Review of ]. JOURNAL OF CLINICAL MEDICINE, 7(6).

By: R. Salgia*, M. Jolly*, T. Dorff*, C. Lau*, K. Weninger n, J. Orban*, P. Kulkarni*

co-author countries: United States of America 🇺🇸
author keywords: PAGE4; prostate cancer; symptomatic BPH; Cancer/Testis Antigen; ADT; IAD
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Publisher Correction: Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study

Nature Methods, 15(11), 984–984.

By: B. Hellenkamp*, S. Schmid*, O. Doroshenko*, O. Opanasyuk*, R. Kühnemuth*, S. Adariani*, B. Ambrose*, M. Aznauryan* ...

co-author countries: Belgium 🇧🇪 Switzerland 🇨🇭 Germany 🇩🇪 Denmark 🇩🇰 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Korea (Republic of) 🇰🇷 Netherlands 🇳🇱 United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2018 journal article

Single Molecule Experiments Reveal Molecular Level Details of MutS-MutL Interactions in DNA Mismatch Activated Sliding Clamp

Biophysical Journal, 114(3), 85a.

By: P. Hao n, S. LeBlanc*, D. Erie* & K. Weninger n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2018 journal article

Single Molecule FRET Observations of Folding for DNA Hairpins Containing Trinucleotide Repeats

Biophysical Journal, 114(3), 599a.

By: P. Xu n & K. Weninger n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2018 review

Single Molecule FRET: A Powerful Tool to Study Intrinsically Disordered Proteins

[Review of ]. BIOMOLECULES, 8(4).

By: S. LeBlanc n, P. Kulkarni* & K. Weninger n

co-author countries: United States of America 🇺🇸
author keywords: single molecule biophysics; FRET; intrinsically disordered protein; IDP
MeSH headings : Fluorescence Resonance Energy Transfer; Intrinsically Disordered Proteins / chemistry; Intrinsically Disordered Proteins / metabolism; Phosphorylation; Single Molecule Imaging
Sources: Web Of Science, ORCID
Added: January 14, 2019

2017 journal article

Dynamic Studies of MutS-MutL-DNA Complexes in Mismatch Repair

Biophysical Journal, 112(3), 516a–517a.

By: S. LeBlanc*, J. Gauer*, P. Hao n, T. Walser n, K. Weninger n & D. Erie*

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2017 journal article

Mismatch Repair on the Go: Extending the Mechanical Model of DNA Mismatch Repair through Single Molecule Study

Biophysical Journal, 112(3), 514a–515a.

By: P. Hao n, R. Qiu*, D. Erie* & K. Weninger n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2017 journal article

Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(13), E2644–E2653.

By: P. Kulkarni*, M. Jolly*, D. Jia*, S. Mooney*, A. Bhargava, L. Kagohara*, Y. Chen*, P. Hao n ...

co-author countries: Canada 🇨🇦 United States of America 🇺🇸
author keywords: intrinsic disorder; androgen resistance; prostate cancer; PAGE-4; phenotypic heterogeneity
MeSH headings : Antigens, Neoplasm / chemistry; Antigens, Neoplasm / metabolism; Humans; Intrinsically Disordered Proteins / chemistry; Intrinsically Disordered Proteins / metabolism; Models, Molecular; Phenotype; Phosphorylation; Protein Conformation; Protein Serine-Threonine Kinases / genetics; Protein Serine-Threonine Kinases / metabolism; Protein Serine-Threonine Kinases / physiology; Protein-Tyrosine Kinases / genetics; Protein-Tyrosine Kinases / metabolism; Protein-Tyrosine Kinases / physiology; Proteome
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Single Molecule Fluorescence and Atomic Force Microscopy Studies of DNA Repair

Biophysical Journal, 112(3), 7a.

By: D. Erie*, K. Bradford*, H. Wilkins*, J. Bower*, Z. Wang*, J. Gauer*, M. Satusky*, R. Qiu n ...

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2016 review

Prostate-associated gene 4 (PAGE4), an intrinsically disordered cancer/testis antigen, is a novel therapeutic target for prostate cancer

[Review of ]. ASIAN JOURNAL OF ANDROLOGY, 18(5), 695–703.

By: P. Kulkarni*, A. Dunker*, K. Weninger* & J. Orban n

co-author countries: United States of America 🇺🇸
author keywords: prostate-associated Gene 4; cancer/testis antigen; intrinsically disordered protein; prostate cancer; c-Jun; AP-1; protein interaction networks; homeodomain-interacting protein 1
MeSH headings : Antigens, Neoplasm / metabolism; Antineoplastic Agents / therapeutic use; Humans; Intrinsically Disordered Proteins / metabolism; Male; Phosphorylation; Prostate / metabolism; Prostate / pathology; Prostatic Neoplasms / drug therapy; Prostatic Neoplasms / metabolism; Prostatic Neoplasms / pathology; Protein Conformation
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Single-molecule FRET to measure conformational dynamics of DNA mismatch repair proteins

Single-Molecule Enzymology: Fluorescence-Based and High-Throughput Methods, 581, 285–315.

By: J. Gauer, S. LeBlanc, P. Hao, R. Qiu, B. Case, M. Sakato, M. Hingorani, D. Erie, K. Weninger

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Venoms from Centruroides sp. Scorpions Cleave SNARE Proteins

Toxicon, 117, 109.

By: P. Fletcher*, M. Fletcher*, K. Weninger n & B. Martin*

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2016 journal article

smFRET and DEER Distance Measurements as Applied to Disordered and Structured Proteins

Biophysical Journal, 110(3), 559a.

By: K. Weninger n, R. Qiu n, E. Ou n, S. Milikisiyants n, H. Sanabria* & T. Smirnova n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2016 journal article

tN-Ras, Synaptotagmin1 C2Ab, Annexinb12 and Amphiphysin NBAR can Discriminate Spherical from Cylindrical Membrane Curvature

Biophysical Journal, 110(3), 357a.

By: A. Breuer*, J. Larsen*, K. Røskva Rosholm, S. Pedersenb*, H. Munch*, V. Tkach*, J. Sakon*, T. Bjørnholm* ...

co-author countries: Denmark 🇩🇰 United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2016 journal article

“Metalloproteases in new world scorpion venoms cleave intracellular membrane fusion SNARE proteins VAMP2 and VAMP8”

“Metalloproteases in new world scorpion venoms cleave intracellular membrane fusion SNARE proteins VAMP2 and VAMP8.” Toxicon, 117, 104.

By: P. Fletcher*, M. Fletcher* & K. Weninger n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2015 journal article

MutL traps MutS at a DNA mismatch

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(35), 10914–10919.

By: R. Qiu n, M. Sakato*, E. Sacho n, H. Wilkins*, X. Zhang*, P. Modrichd, M. Hingorani*, D. Erie*, K. Weninger n

co-author countries: United States of America 🇺🇸
author keywords: DNA mismatch repair; MutS; MutL; FRET
MeSH headings : Bacterial Proteins / genetics; Base Pair Mismatch; Genes, Bacterial; Thermus / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Phosphorylation-induced Conformational Ensemble Switching in an Intrinsically Disordered Cancer/Testis Antigen

JOURNAL OF BIOLOGICAL CHEMISTRY, 290(41), 25090–25102.

By: Y. He*, Y. Chen*, S. Mooney*, K. Rajagopalan*, A. Bhargava, E. Sacho n, keith, P. Bryan* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Antigens, Neoplasm / chemistry; Antigens, Neoplasm / metabolism; Cell Line, Tumor; Humans; Male; Models, Molecular; Molecular Sequence Data; Phosphorylation; Prostatic Neoplasms / pathology; Protein Conformation
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Toward Adding Complexity in Single Molecule FRET Studies of DNA Mismatch Repair

Biophysical Journal, 108(2), 69a–70a.

By: k. weninger n, P. Hao n, Y. Yang n, E. Sacho n & R. Qiu n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: February 5, 2020

2014 journal article

Cancer/Testis Antigen PAGE4, a Regulator of c-Jun Transactivation, Is Phosphorylated by Homeodomain-Interacting Protein Kinase 1, a Component of the Stress-Response Pathway

BIOCHEMISTRY, 53(10), 1670–1679.

By: S. Mooney, R. Qiu n, J. Kim*, E. Sacho n, K. Rajagopalan, D. Johng*, T. Shiraishi, P. Kulkarni, K. Weninger n

co-author countries: United States of America 🇺🇸
MeSH headings : Amino Acid Motifs; Antigens, Neoplasm / chemistry; Antigens, Neoplasm / genetics; Antigens, Neoplasm / metabolism; Cell Line, Tumor; Humans; Male; Phosphorylation; Prostatic Neoplasms / enzymology; Prostatic Neoplasms / genetics; Prostatic Neoplasms / metabolism; Prostatic Neoplasms / physiopathology; Protein Binding; Protein Serine-Threonine Kinases / genetics; Protein Serine-Threonine Kinases / metabolism; Proto-Oncogene Proteins c-jun / genetics; Proto-Oncogene Proteins c-jun / metabolism; Signal Transduction; Stress, Physiological; Testis / metabolism; Transcriptional Activation
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Dynamics of MutS-Mismatched DNA Complexes Are Predictive of Their Repair Phenotypes

BIOCHEMISTRY, 53(12), 2043–2052.

By: V. DeRocco*, L. Sass, R. Qiu n, K. Weninger n & D. Erie

co-author countries: United States of America 🇺🇸
MeSH headings : Bacterial Proteins / chemistry; Bacterial Proteins / genetics; DNA Repair / genetics; Fluorescence Resonance Energy Transfer; INDEL Mutation; MutS DNA Mismatch-Binding Protein / chemistry; MutS DNA Mismatch-Binding Protein / genetics; Phenotype; Predictive Value of Tests; Signal Transduction / genetics; Thermus / enzymology; Thermus / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Investigation of Calcein for Reporting Content Mixing During Viral Membrane Fusion Experiments

Biophysical Journal, 106(2), 707a.

By: L. Wessels* & K. Weninger n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: September 8, 2020

2014 journal article

Single molecule studies of DNA mismatch repair

DNA REPAIR, 20, 71–81.

By: D. Erie* & K. Weninger n

co-author countries: United States of America 🇺🇸
author keywords: Mismatch repair; One-dimensional diffusion; Single-molecule fluorescence; FRET; Atomic force microscopy; AFM; Single particle tracking; Protein-DNA interactions
MeSH headings : Amino Acid Sequence; Animals; DNA Mismatch Repair; DNA Repair Enzymes / chemistry; Fluorescence Resonance Energy Transfer / methods; Humans; Microscopy, Atomic Force / methods; Molecular Sequence Data; Optical Tweezers
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

The Stress-response protein prostate-associated gene 4, interacts with c-Jun and potentiates its transactivation

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1842(2), 154–163.

By: K. Rajagopalan*, R. Qiu n, S. Mooney*, S. Rao*, T. Shiraishi*, E. Sacho n, H. Huang*, E. Shapiro* ...

co-author countries: United States of America 🇺🇸
author keywords: PAGE4; Cancer/Testis Antigen; c-Jun; smFRET; Prostate cancer; Intrinsically disordered protein
MeSH headings : 3' Untranslated Regions / genetics; Antigens, Neoplasm / chemistry; Antigens, Neoplasm / genetics; Antigens, Neoplasm / metabolism; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p27 / genetics; Cyclin-Dependent Kinase Inhibitor p27 / metabolism; Fluorescence Resonance Energy Transfer; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; MicroRNAs / genetics; MicroRNAs / metabolism; Mutation; Prostate / embryology; Prostate / growth & development; Prostate / metabolism; Prostatic Neoplasms / genetics; Prostatic Neoplasms / metabolism; Prostatic Neoplasms / pathology; Protein Binding; Protein Conformation; Proto-Oncogene Mas; Proto-Oncogene Proteins c-jun / genetics; Proto-Oncogene Proteins c-jun / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Stress, Physiological; Transcriptional Activation
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Dynamics of DNA Mismatch Repair Initiation Complex Revealed by Single Molecule Fluorescence

Biophysical Journal, 104(2), 368a.

By: R. Qiu n & K. Weninger n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: September 8, 2020

2012 journal article

Conformational Changes in MutS during Mismtach Repair Signaling Determined with Single Molecule FRET

Biophysical Journal, 102(3), 283a.

By: R. Qiu n & K. Weninger n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: September 8, 2020

2012 journal article

Cooperative All-Or-None Recruitment of Synaptotagmin C2AB on Single Vesicles Explains Why Ca2+ Regulates the Amplitude of SNARE Mediated Vesicle Fusion

Biophysical Journal, 102(3), 318a–319a.

co-author countries: Denmark 🇩🇰 United States of America 🇺🇸
Sources: Crossref, ORCID
Added: September 8, 2020

2012 journal article

Dynamics of DNA Mismatch Repair Revealed by Single Molecule FRET

Biophysical Journal, 102(3), 235a.

By: K. Weninger n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: December 27, 2020

2012 journal article

Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling

EMBO JOURNAL, 31(11), 2528–2540.

By: R. Qiu n, V. DeRocco*, C. Harris*, A. Sharma*, M. Hingorani*, D. Erie*, K. Weninger n

co-author countries: United States of America 🇺🇸
author keywords: DNA mismatch repair; MMR; MutS; protein conformational change; sliding clamp
MeSH headings : Adenosine Diphosphate / chemistry; Adenosine Triphosphate / chemistry; DNA Mismatch Repair / genetics; DNA Mismatch Repair / physiology; Fluorescence Resonance Energy Transfer; MutS DNA Mismatch-Binding Protein / chemistry; MutS DNA Mismatch-Binding Protein / genetics; MutS DNA Mismatch-Binding Protein / metabolism; Protein Conformation
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 chapter

Macromolecular Models by Single Molecule FRET

In NATO Science for Peace and Security Series B: Physics and Biophysics (pp. 1–19).

By: A. Brunger*, P. Strop*, M. Vrljic*, M. Bowen*, S. Chu* & K. Weninger n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: September 8, 2020

2012 journal article

Opacity and Transport Measurements Reveal That Dilute Plasma Models of Sonoluminescence Are Not Valid

PHYSICAL REVIEW LETTERS, 108(10).

By: S. Khalid, B. Kappus*, K. Weninger n & S. Putterman*

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Single Molecule FRET Studies of the DNA Mismatch Repair Protein MutSα using Specific Labeling with Unnatural Amino Acids

Biophysical Journal, 102(3), 282a.

By: E. Sacho n & K. Weninger n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: September 8, 2020

2011 journal article

Beyond the Random Coil: Stochastic Conformational Switching in Intrinsically Disordered Proteins

STRUCTURE, 19(4), 566–576.

By: U. Choi n, J. McCann*, K. Weninger n & M. Bowen*

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 article

Complexin arrests a neighbor

Weninger, K. R. (2011, August). NATURE STRUCTURAL & MOLECULAR BIOLOGY, Vol. 18, pp. 861–863.

By: K. Weninger n

co-author countries: United States of America 🇺🇸
MeSH headings : Adaptor Proteins, Signal Transducing / physiology; Adaptor Proteins, Vesicular Transport / chemistry; Animals; Humans; Nerve Tissue Proteins / chemistry; SNARE Proteins / chemistry; Synaptotagmins / physiology; Vesicle-Associated Membrane Protein 2 / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Single Molecule FRET Study of Nucleotide Binding Effects on Muts Proteins

Biophysical Journal, 100(3), 223a.

By: R. Qiu & K. Weninger*

Sources: Crossref, ORCID
Added: September 8, 2020

2011 journal article

Three-dimensional molecular modeling with single molecule FRET

JOURNAL OF STRUCTURAL BIOLOGY, 173(3), 497–505.

By: A. Brunger*, P. Strop*, M. Vrljic*, S. Chu* & K. Weninger n

co-author countries: United States of America 🇺🇸
author keywords: Single molecule fluorescence; FRET; Molecular dynamics; Protein-protein interactions
MeSH headings : Computer Simulation; Fluorescence Resonance Energy Transfer / methods; Fluorescent Dyes / chemistry; Image Processing, Computer-Assisted; Macromolecular Substances / chemistry; Models, Molecular; Molecular Conformation
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Detecting the conformation of individual proteins in live cells

NATURE METHODS, 7(3), 203–U56.

By: J. Sakon n & K. Weninger n

co-author countries: United States of America 🇺🇸
MeSH headings : Cells, Cultured; Fluorescence Resonance Energy Transfer; Humans; Membrane Fusion; Protein Conformation; Protein Folding; SNARE Proteins / chemistry; Synaptosomal-Associated Protein 25
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Four-color single-molecule fluorescence with noncovalent dye labeling to monitor dynamic multimolecular complexes

BIOTECHNIQUES, 49(5), 807-+.

By: V. DeRocco*, T. Anderson n, J. Piehler*, D. Erie* & K. Weninger n

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: FRET; MutS; Msh2; Msh6; DNA mismatch repair; SNARE proteins; Munc-18
MeSH headings : Coloring Agents; DNA / chemistry; DNA Mismatch Repair; Energy Transfer; Fluorescence Resonance Energy Transfer / methods; Histidine; Macromolecular Substances / chemistry; MutS DNA Mismatch-Binding Protein / analysis; MutS DNA Mismatch-Binding Protein / chemistry; MutS DNA Mismatch-Binding Protein / pharmacology; Nitrilotriacetic Acid; Nucleic Acid Conformation / drug effects; Protein Conformation / drug effects; SNARE Proteins / chemistry; Tromethamine
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Optimizing Methods to Recover Absolute FRET Efficiency from Immobilized Single Molecules

BIOPHYSICAL JOURNAL, 99(3), 961–970.

By: J. McCann*, U. Choi n, L. Zheng*, K. Weninger n & M. Bowen*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Base Sequence; DNA / chemistry; DNA / genetics; Disks Large Homolog 4 Protein; Fluorescence Resonance Energy Transfer / methods; Immobilized Proteins / chemistry; Intracellular Signaling Peptides and Proteins / chemistry; Membrane Proteins / chemistry; Molecular Sequence Data; Mutant Proteins / chemistry; Photobleaching; Rats; Reference Standards
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Recovering Absolute Fret Efficiency from Single Molecules: Comparing Methods of Gamma Correction

Biophysical Journal, 98(3), 186a–187a.

By: J. McCann*, U. Choi*, L. Zheng*, K. Weninger n & M. Bowen*

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: September 8, 2020

2010 journal article

Single-Molecule FRET TACKLE Reveals Highly Dynamic Mismatched DNA-MutS Complexes

BIOCHEMISTRY, 49(14), 3174–3190.

By: L. Sass, C. Lanyi, K. Weninger n & D. Erie

co-author countries: United States of America 🇺🇸
MeSH headings : Base Pair Mismatch; DNA / chemistry; Fluorescence Resonance Energy Transfer; Kinetics; MutS DNA Mismatch-Binding Protein / chemistry; Nucleic Acid Conformation; Protein Binding; Protein Conformation
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 17(3), 318–U84.

By: U. Choi n, P. Strop*, M. Vrljic*, S. Chu*, A. Brunger* & K. Weninger n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Calcium / metabolism; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Fluorescence Resonance Energy Transfer; Protein Binding; Rats; Recombinant Fusion Proteins / chemistry; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / metabolism; SNARE Proteins / chemistry; SNARE Proteins / genetics; SNARE Proteins / metabolism; Synaptotagmin I / chemistry; Synaptotagmin I / genetics; Synaptotagmin I / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Vesicle-associated Membrane Protein (VAMP) Cleavage by a New Metalloprotease from the Brazilian Scorpion Tityus serrulatus

JOURNAL OF BIOLOGICAL CHEMISTRY, 285(10), 7405–7416.

By: P. Fletcher*, M. Fletcher*, K. Weninger n, T. Anderson n & B. Martin*

co-author countries: United States of America 🇺🇸
MeSH headings : Amino Acid Sequence; Animals; Guinea Pigs; Immunohistochemistry; Metalloproteases / metabolism; Metalloproteases / ultrastructure; Models, Molecular; Molecular Sequence Data; Pancreas, Exocrine / anatomy & histology; Pancreas, Exocrine / metabolism; Protein Conformation; Protein Isoforms / metabolism; R-SNARE Proteins / metabolism; R-SNARE Proteins / ultrastructure; SNARE Proteins / metabolism; Scorpion Venoms / enzymology; Scorpions / enzymology; Secretory Vesicles / chemistry; Secretory Vesicles / ultrastructure
Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 journal article

Fluorescence quenching effects of nanocrystalline diamond surfaces

DIAMOND AND RELATED MATERIALS, 18(1), 82–87.

By: J. Sakon, G. Ribeill, J. Garguilo*, J. Perkins, K. Weninger* & R. Nemanich*

author keywords: Nanocrystalline; Diamond film; Biocompatibility; Optical properties
Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 article

How Do Adhesion Proteins Stick?

Weninger, K. (2009, August 12). STRUCTURE, Vol. 17, pp. 1035–1036.

By: K. Weninger n

co-author countries: United States of America 🇺🇸
MeSH headings : Binding Sites / genetics; Cadherins / chemistry; Cadherins / genetics; Cadherins / metabolism; Calcium / chemistry; Calcium / pharmacology; Cell Line; Fluorescence Resonance Energy Transfer; Humans; Microscopy, Atomic Force; Mutation; Protein Binding; Protein Conformation / drug effects; Protein Multimerization; Protein Structure, Tertiary; Transfection; Tryptophan / chemistry; Tryptophan / genetics; Tryptophan / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 journal article

Photoinactivation of Sindbis Virus Infectivity Without Inhibition of Membrane Fusion

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 85(3), 801–806.

By: W. Thongthai n & K. Weninger n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cells, Cultured; Cricetinae; Electrophoresis, Polyacrylamide Gel; Liposomes; Membrane Fusion; Sindbis Virus / pathogenicity; Sindbis Virus / radiation effects; Virulence / radiation effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 review

Physical Aspects of Viral Membrane Fusion

[Review of ]. THESCIENTIFICWORLDJOURNAL, 9, 764–780.

By: L. Wessels n & K. Weninger n

co-author countries: United States of America 🇺🇸
author keywords: viral membrane fusion; class I, II, and III fusion proteins; hemagluttin (HA); E1; gp64
MeSH headings : Membrane Fusion; Protein Conformation; Viral Proteins / chemistry; Virus Physiological Phenomena
Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 article

Single-Molecule Studies of the Neuronal SNARE Fusion Machinery

ANNUAL REVIEW OF BIOCHEMISTRY, Vol. 78, pp. 903–928.

By: A. Brunger*, K. Weninger n, M. Bowen* & S. Chu

co-author countries: United States of America 🇺🇸
author keywords: FRET; membrane fusion; neurotransmission; synaptic vesicle
MeSH headings : Animals; Fluorescence; Humans; Microscopy, Atomic Force; Neurons / chemistry; Neurons / metabolism; SNARE Proteins / chemistry; SNARE Proteins / metabolism; Spectrum Analysis / methods; Synaptotagmins / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Accessory proteins stabilize the acceptor complex for synaptobrevin, the 1 : 1 syntaxin/SNAP-25 complex

STRUCTURE, 16(2), 308–320.

By: K. Weninger n, M. Bowen*, U. Choi n, S. Chu* & A. Brunger*

co-author countries: United States of America 🇺🇸
MeSH headings : Fluorescence Resonance Energy Transfer; Lipid Bilayers / metabolism; Protein Structure, Tertiary; Qa-SNARE Proteins / chemistry; Qa-SNARE Proteins / metabolism; R-SNARE Proteins / metabolism; SNARE Proteins / metabolism; Synaptosomal-Associated Protein 25 / chemistry; Synaptosomal-Associated Protein 25 / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Infection of cells by Sindbis virus at low temperature

Virology, 362(2), 461–467.

By: G. Wang n, R. Hernandez n, keith & D. Brown n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Cell Fusion; Cell Line; Cricetinae; Endocytosis; Microscopy, Immunoelectron; Neutral Red / metabolism; Sindbis Virus / physiology; Temperature; Time Factors; Viral Plaque Assay; Virus Internalization
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2007 journal article

Kinetics of complexin binding to the SNARE complex: Correcting single molecule FRET measurements for hidden events

BIOPHYSICAL JOURNAL, 93(6), 2178–2187.

By: Y. Li*, G. Augustine* & K. Weninger n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Binding Sites; Biophysical Phenomena; Biophysics; Fluorescence Resonance Energy Transfer; In Vitro Techniques; Kinetics; Ligands; Liposomes; Microscopy, Fluorescence; Models, Molecular; Multiprotein Complexes; Nerve Tissue Proteins / chemistry; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; Protein Binding; Rats; Recombinant Fusion Proteins / chemistry; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / metabolism; SNARE Proteins / chemistry; SNARE Proteins / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Rapid membrane fusion of individual virus particles with supported lipid bilayers

BIOPHYSICAL JOURNAL, 93(2), 526–538.

By: L. Wessels n, M. Elting n, D. Scimeca n & K. Weninger n

co-author countries: United States of America 🇺🇸

Contributors: L. Wessels n, M. Elting n, D. Scimeca n & K. Weninger n

MeSH headings : Animals; Biophysical Phenomena; Biophysics; Chick Embryo; Cricetinae; Fluorescent Dyes; Hydrogen-Ion Concentration; In Vitro Techniques; Influenza A Virus, H3N2 Subtype / physiology; Lipid Bilayers / chemistry; Membrane Fusion / physiology; Models, Biological; Rhodamines; Sindbis Virus / physiology; Virion / physiology
Sources: Web Of Science, ORCID
Added: August 6, 2018

Funding History

Funding history based on the linked ORCID record. Updated: February 16th, 2021 12:30

grant July 25, 2019 - May 31, 2023
Molecular mechanisms of DNA mismatch repair initiation
National Institute of General Medical Sciences
grant September 15, 2017 - August 31, 2021
Fast single-molecule refractive index binding sensor
National Institute of General Medical Sciences
grant July 1, 2016 - April 30, 2021
Trinucleotide Repeats: Atypical Structures, Diseases, and Evolution
National Institute of General Medical Sciences
grant June 1, 2014 - May 31, 2019
Quantitative analysis of transient DNA repair processes in vivo
National Institute of General Medical Sciences
grant May 1, 2006 - August 31, 2009
Detecting Individual Protein Conformation in Live Cells
National Institute of General Medical Sciences

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