Keith R. Weninger

A nanophotonic interferometer

NANOTECHNOLOGY, 34(18).

Frustration Between Preferred States of Complementary Trinucleotide Repeat DNA Hairpins Anticorrelates with Expansion Disease Propensity

JOURNAL OF MOLECULAR BIOLOGY, 435(10).

Illuminating Intrinsically Disordered Proteins with Integrative Structural Biology

[Review of ]. BIOMOLECULES, 13(1).

A Nanophotonic Interferometer for small particle detection

INTERFEROMETRY XXI, Vol. 12223.

A blind benchmark of analysis tools to infer kinetic rate constants from single-molecule FRET trajectories

NATURE COMMUNICATIONS, 13(1).

Non-ergodicity of a globular protein extending beyond its functional timescale

Li, J., Xie, J. F., Godec, A., Weninger, K. R., Liu, C., Smith, J. C., & Hong, L. (2022, August 4). CHEMICAL SCIENCE, Vol. 8.

Integrative structural dynamics probing of the conformational heterogeneity in synaptosomal-associated protein 25

CELL REPORTS PHYSICAL SCIENCE, 2(11).

Molecular conformations and dynamics of nucleotide repeats associated with neurodegenerative diseases: double helices and CAG hairpin loops

[Review of ]. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 19, 2819–2832.

Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA

JOURNAL OF BIOLOGICAL CHEMISTRY, 297(3).

Dynamic human MutS alpha-MutL alpha complexes compact mismatched DNA

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117(28), 16302–16312.

Dynamics of strand slippage in DNA hairpins formed by CAG repeats: roles of sequence parity and trinucleotide interrupts

Nucleic Acids Research, 1.

How Membrane Geometry Regulates Protein Sorting Independently of Mean Curvature

ACS CENTRAL SCIENCE, 6(7), 1159–1168.

Recurrent mismatch binding by MutS mobile clamps on DNA localizes repair complexes nearby

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117(30), 17775–17784.

Investigating the Function of Mutl Conformational Changes in Mismatch Repair using smFRET

Biophysical Journal, 116(3), 49a–50a.

Spontaneous Switching among Conformational Ensembles in Intrinsically Disordered Proteins

[Review of ]. BIOMOLECULES, 9(3).

Structural and Dynamical Order of a Disordered Protein: Molecular Insights into Conformational Switching of PAGE4 at the Systems Level

Biomolecules, 9(2), 77.

TIN2 is an Architectural Protein Stabilizing TRF1 at Telomere

Biophysical Journal, 116(3), 211a–212a.

Toward Single Molecule FRET Studies of DNA Mismatch Repair in Live Bacteria

Biophysical Journal, 116(3), 139a.

Untangling DNA Mismatch Repair Complexes with smFRET and Tethered Particle Motion Analysis

Biophysical Journal, 116(3), 77a.

Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS

NUCLEIC ACIDS RESEARCH, 46(20), 10782–10795.

Motor-like DNA motion due to an ATP-hydrolyzing protein under nanoconfinement

Scientific Reports, 8(1).

PAGE4 and Conformational Switching: Insights from Molecular Dynamics Simulations and Implications for Prostate Cancer

Journal of Molecular Biology, 430(16), 2422–2438.

Phenotypic Plasticity, Bet-Hedging, and Androgen Independence in Prostate Cancer: Role of Non-Genetic Heterogeneity

[Review of ]. FRONTIERS IN ONCOLOGY, 8.

Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study

NATURE METHODS, 15(9), 669-+.

Prostate-Associated Gene 4 (PAGE4): Leveraging the Conformational Dynamics of a Dancing Protein Cloud as a Therapeutic Target

[Review of ]. JOURNAL OF CLINICAL MEDICINE, 7(6).

Publisher Correction: Precision and accuracy of single-molecule FRET measurements—a multi-laboratory benchmark study

Nature Methods, 15(11), 984–984.

Single Molecule Experiments Reveal Molecular Level Details of MutS-MutL Interactions in DNA Mismatch Activated Sliding Clamp

Biophysical Journal, 114(3), 85a.

Single Molecule FRET Observations of Folding for DNA Hairpins Containing Trinucleotide Repeats

Biophysical Journal, 114(3), 599a.

Single Molecule FRET: A Powerful Tool to Study Intrinsically Disordered Proteins

[Review of ]. BIOMOLECULES, 8(4).

Dynamic Studies of MutS-MutL-DNA Complexes in Mismatch Repair

Biophysical Journal, 112(3), 516a–517a.

Mismatch Repair on the Go: Extending the Mechanical Model of DNA Mismatch Repair through Single Molecule Study

Biophysical Journal, 112(3), 514a–515a.

Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(13), E2644–E2653.

Single Molecule Fluorescence and Atomic Force Microscopy Studies of DNA Repair

Biophysical Journal, 112(3), 7a.

Prostate-associated gene 4 (PAGE4), an intrinsically disordered cancer/testis antigen, is a novel therapeutic target for prostate cancer

[Review of ]. ASIAN JOURNAL OF ANDROLOGY, 18(5), 695–703.

Single-molecule FRET to measure conformational dynamics of DNA mismatch repair proteins

Single-Molecule Enzymology: Fluorescence-Based and High-Throughput Methods, 581, 285–315.

Venoms from Centruroides sp. Scorpions Cleave SNARE Proteins

Toxicon, 117, 109.

smFRET and DEER Distance Measurements as Applied to Disordered and Structured Proteins

Biophysical Journal, 110(3), 559a.

tN-Ras, Synaptotagmin1 C2Ab, Annexinb12 and Amphiphysin NBAR can Discriminate Spherical from Cylindrical Membrane Curvature

Biophysical Journal, 110(3), 357a.

“Metalloproteases in new world scorpion venoms cleave intracellular membrane fusion SNARE proteins VAMP2 and VAMP8”

“Metalloproteases in new world scorpion venoms cleave intracellular membrane fusion SNARE proteins VAMP2 and VAMP8.” Toxicon, 117, 104.

MutL traps MutS at a DNA mismatch

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(35), 10914–10919.

Phosphorylation-induced Conformational Ensemble Switching in an Intrinsically Disordered Cancer/Testis Antigen

JOURNAL OF BIOLOGICAL CHEMISTRY, 290(41), 25090–25102.

Toward Adding Complexity in Single Molecule FRET Studies of DNA Mismatch Repair

Biophysical Journal, 108(2), 69a–70a.

Cancer/Testis Antigen PAGE4, a Regulator of c-Jun Transactivation, Is Phosphorylated by Homeodomain-Interacting Protein Kinase 1, a Component of the Stress-Response Pathway

BIOCHEMISTRY, 53(10), 1670–1679.

Dynamics of MutS-Mismatched DNA Complexes Are Predictive of Their Repair Phenotypes

BIOCHEMISTRY, 53(12), 2043–2052.

Investigation of Calcein for Reporting Content Mixing During Viral Membrane Fusion Experiments

Biophysical Journal, 106(2), 707a.

Single molecule studies of DNA mismatch repair

DNA REPAIR, 20, 71–81.

The Stress-response protein prostate-associated gene 4, interacts with c-Jun and potentiates its transactivation

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1842(2), 154–163.

Dynamics of DNA Mismatch Repair Initiation Complex Revealed by Single Molecule Fluorescence

Biophysical Journal, 104(2), 368a.

Conformational Changes in MutS during Mismtach Repair Signaling Determined with Single Molecule FRET

Biophysical Journal, 102(3), 283a.

Cooperative All-Or-None Recruitment of Synaptotagmin C2AB on Single Vesicles Explains Why Ca2+ Regulates the Amplitude of SNARE Mediated Vesicle Fusion

Biophysical Journal, 102(3), 318a–319a.

Dynamics of DNA Mismatch Repair Revealed by Single Molecule FRET

Biophysical Journal, 102(3), 235a.

Large conformational changes in MutS during DNA scanning, mismatch recognition and repair signalling

EMBO JOURNAL, 31(11), 2528–2540.

Macromolecular Models by Single Molecule FRET

In NATO Science for Peace and Security Series B: Physics and Biophysics (pp. 1–19).

Opacity and Transport Measurements Reveal That Dilute Plasma Models of Sonoluminescence Are Not Valid

PHYSICAL REVIEW LETTERS, 108(10).

Single Molecule FRET Studies of the DNA Mismatch Repair Protein MutSα using Specific Labeling with Unnatural Amino Acids

Biophysical Journal, 102(3), 282a.

Beyond the Random Coil: Stochastic Conformational Switching in Intrinsically Disordered Proteins

STRUCTURE, 19(4), 566–576.

Complexin arrests a neighbor

Weninger, K. R. (2011, August). NATURE STRUCTURAL & MOLECULAR BIOLOGY, Vol. 18, pp. 861–863.

Single Molecule FRET Study of Nucleotide Binding Effects on Muts Proteins

Biophysical Journal, 100(3), 223a.

Three-dimensional molecular modeling with single molecule FRET

JOURNAL OF STRUCTURAL BIOLOGY, 173(3), 497–505.

Detecting the conformation of individual proteins in live cells

NATURE METHODS, 7(3), 203–U56.

Four-color single-molecule fluorescence with noncovalent dye labeling to monitor dynamic multimolecular complexes

BIOTECHNIQUES, 49(5), 807-+.

Optimizing Methods to Recover Absolute FRET Efficiency from Immobilized Single Molecules

BIOPHYSICAL JOURNAL, 99(3), 961–970.

Recovering Absolute Fret Efficiency from Single Molecules: Comparing Methods of Gamma Correction

Biophysical Journal, 98(3), 186a–187a.

Single-Molecule FRET TACKLE Reveals Highly Dynamic Mismatched DNA-MutS Complexes

BIOCHEMISTRY, 49(14), 3174–3190.

Single-molecule FRET-derived model of the synaptotagmin 1-SNARE fusion complex

NATURE STRUCTURAL & MOLECULAR BIOLOGY, 17(3), 318–U84.

Vesicle-associated Membrane Protein (VAMP) Cleavage by a New Metalloprotease from the Brazilian Scorpion Tityus serrulatus

JOURNAL OF BIOLOGICAL CHEMISTRY, 285(10), 7405–7416.

Fluorescence quenching effects of nanocrystalline diamond surfaces

DIAMOND AND RELATED MATERIALS, 18(1), 82–87.

How Do Adhesion Proteins Stick?

Weninger, K. (2009, August 12). STRUCTURE, Vol. 17, pp. 1035–1036.

Photoinactivation of Sindbis Virus Infectivity Without Inhibition of Membrane Fusion

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 85(3), 801–806.

Physical Aspects of Viral Membrane Fusion

[Review of ]. THESCIENTIFICWORLDJOURNAL, 9, 764–780.

Single-Molecule Studies of the Neuronal SNARE Fusion Machinery

ANNUAL REVIEW OF BIOCHEMISTRY, Vol. 78, pp. 903–928.

Accessory proteins stabilize the acceptor complex for synaptobrevin, the 1 : 1 syntaxin/SNAP-25 complex

STRUCTURE, 16(2), 308–320.

Infection of cells by Sindbis virus at low temperature

Virology, 362(2), 461–467.

Kinetics of complexin binding to the SNARE complex: Correcting single molecule FRET measurements for hidden events

BIOPHYSICAL JOURNAL, 93(6), 2178–2187.

Rapid membrane fusion of individual virus particles with supported lipid bilayers

BIOPHYSICAL JOURNAL, 93(2), 526–538.