Kim Suzanne Bellingham-Johnstun

Works (6)

Updated: April 5th, 2024 13:39

2023 journal article

Actin-Microtubule Crosstalk Imparts Stiffness to the Contractile Ring in Fission Yeast

CELLS, 12(6).

By: K. Bellingham-Johnstun n, Z. Tyree n, J. Martinez-Baird n, A. Thorn n & C. Laplante n

author keywords: cytokinesis; mitosis; microtubules; mechanical properties; contractile ring; quantitative microscopy
MeSH headings : Actins; Schizosaccharomyces; Microtubules; Cytoskeleton; Cell Division
TL;DR: It is proposed that the post-anaphase array of microtubules exploit the contractile ring for their assembly and function during cell division, while the contractiles ring may receive no benefit from these interactions. (via Semantic Scholar)
Source: Web Of Science
Added: April 11, 2023

2023 journal article

Microtubule competition and cell growth recenter the nucleus after anaphase in fission yeast

MOLECULAR BIOLOGY OF THE CELL, 34(8).

By: K. Bellingham-Johnstun n, A. Thorn n, J. Belmonte n & C. Laplante n

TL;DR: This work underlines how intrinsic properties of microtubules differently impact nuclear positioning according to microtubule network organization and cell size. (via Semantic Scholar)
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Source: Web Of Science
Added: August 28, 2023

2022 journal article

Imp2p forms actin-dependent clusters and imparts stiffness to the contractile ring

MOLECULAR BIOLOGY OF THE CELL, 33(14).

By: K. Bellingham-Johnstun n, B. Commer n, B. Levesque n, Z. Tyree n & C. Laplante n

MeSH headings : Actin Cytoskeleton / metabolism; Actins / metabolism; Cytokinesis; Schizosaccharomyces / metabolism; Schizosaccharomyces pombe Proteins / metabolism
TL;DR: It is found that similarly to Cdc15p, Imp2p contributes to the stiffness of the contractile ring and assembles into protein clusters, indicating that the two proteins influence each other during cytokinesis, which may partially explain their similar phenotypes. (via Semantic Scholar)
Source: Web Of Science
Added: January 3, 2023

2022 journal article

Laser ablation reveals the impact of Cdc15p on the stiffness of the contractile ring

MOLECULAR BIOLOGY OF THE CELL, 33(6).

By: M. Moshtohry n, K. Bellingham-Johnstun n, M. Elting n & C. Laplante n

MeSH headings : Actin Cytoskeleton / metabolism; Cytokinesis; Laser Therapy; Schizosaccharomyces / metabolism; Schizosaccharomyces pombe Proteins / metabolism
TL;DR: This work shows that the severed constricting contractile ring recoils to a finite point leaving a gap that can heal if less than ∼1 µm, and proposes that Cdc15p impacts the stiffness of the contractiles ring more than the viscous drag. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 6, 2022

2021 journal article

Host-Pathogen Interactions of Chlamydia trachomatis in Porcine Oviduct Epithelial Cells

PATHOGENS, 10(10).

By: A. Amaral n, B. McQueen*, K. Bellingham-Johnstun n, T. Poston*, T. Darville*, U. Nagarajan*, C. Laplante n, T. Kaser n

author keywords: Chlamydia trachomatis; porcine oviduct epithelial cell; developmental cycle; innate immune response; claudin-4; tight junctions
TL;DR: It is shown that primary pOECs represent an excellent in vitro model for research into Ct pathogenesis, cell biology and immunity and induces an immune response to Ct similar to human cells. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: October 6, 2021

2021 journal article

Molecular organization of cytokinesis node predicts the constriction rate of the contractile ring

JOURNAL OF CELL BIOLOGY, 220(3).

By: K. Bellingham-Johnstun n, E. Anders n, J. Ravi n, C. Bruinsma n & C. Laplante n

MeSH headings : Acetyltransferases / metabolism; Actin Cytoskeleton / metabolism; Actins / metabolism; Cytokinesis; Models, Biological; Mutation / genetics; Schizosaccharomyces / cytology; Schizosaccharomyces / metabolism; Schizosaccharomyces pombe Proteins / genetics; Schizosaccharomyces pombe Proteins / metabolism; Time Factors
TL;DR: This work leveraged the Δmid1 contractile ring assembly mechanism to determine how two distinct molecular organizations, nodes versus strands, can yield functional contractile rings and establishes a predictive correlation between the molecular organization of nodes and the behavior of the contractiles ring. (via Semantic Scholar)
Source: Web Of Science
Added: March 29, 2021

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