Kevin Volkel

Works (5)

Updated: September 4th, 2024 05:02

2024 journal article

A primordial DNA store and compute engine

Nature Nanotechnology, 8.

By: K. Lin n, K. Volkel n, C. Cao n, P. Hook *, R. Polak n , A. Clark n, A. San Miguel n , W. Timp * ...

Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: August 25, 2024

2023 journal article

FrameD: framework for DNA-based data storage design, verification, and validation

BIOINFORMATICS, 39(10).

By: K. Volkel n, K. Lin n, P. Hook *, W. Timp *, A. Keung n  & J. Tuck n 

Ed(s): J. Kelso

TL;DR: FrameD fills a void in the tools publicly available to the DNA storage community by providing a modular and extensible framework with support for massive parallelism that will help accelerate the design process of future DNA-based storage systems. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 11, 2023

2022 journal article

DINOS: Data INspired Oligo Synthesis for DNA Data Storage

ACM JOURNAL ON EMERGING TECHNOLOGIES IN COMPUTING SYSTEMS, 18(3).

By: K. Volkel n, K. Tomek n, A. Keung n  & J. Tuck n 

author keywords: DNA information storage; DNA synthesis; DNA assembly algorithms
TL;DR: The approach offers greater density by up to 80% over a prior general purpose gene assembly technique, and in an analysis of synthesis costs, it is estimated that DINOS is as 105× cheaper than de novo synthesis. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 14, 2022

2021 journal article

Promiscuous molecules for smarter file operations in DNA-based data storage

NATURE COMMUNICATIONS, 12(1).

By: K. Tomek n, K. Volkel n, E. Indermaur n, J. Tuck n  & A. Keung n 

MeSH headings : Computer Simulation; DNA / chemistry; DNA Primers / chemistry; Databases, Nucleic Acid; High-Throughput Nucleotide Sequencing; Image Processing, Computer-Assisted / methods; Information Storage and Retrieval / methods; Real-Time Polymerase Chain Reaction / methods; Software; Temperature; Thermodynamics
TL;DR: The authors leverage thermodynamics to control the access of different subsets of data in a file and provide an argument for the substantial and practical economic benefit of this generalizable strategy to organize data. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 12, 2021

2020 journal article

Dynamic and scalable DNA-based information storage

NATURE COMMUNICATIONS, 11(1).

By: K. Lin n, K. Volkel n, J. Tuck n  & A. Keung n 

MeSH headings : Algorithms; Bacteriophage T7 / genetics; DNA / genetics; DNA, Single-Stranded / genetics; Gene Expression Regulation, Viral; Genetic Code; Models, Genetic; Promoter Regions, Genetic / genetics; Transcription, Genetic
TL;DR: It is shown that a simple architecture comprised of a T7 promoter and a single-stranded overhang domain (ss-dsDNA), can unlock dynamic DNA-based information storage with powerful capabilities and advantages. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 13, 2020

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