Works (51)

2021 chapter

Fast-Scan for In Vivo Measurements of Neurochemical Dynamics

In M. Fakhoury (Ed.), The Brain Reward System (pp. 93–123).

By: C. Meunier & L. Sombers

Ed(s): M. Fakhoury

Sources: Crossref, ORCID
Added: February 6, 2021

2020 journal article

Carbon-Fiber Nanoelectrodes for Real-Time Discrimination of Vesicle Cargo in the Native Cellular Environment

ACS Nano, 14(3), 2917–2926.

By: J. Roberts, E. Mitchell, L. Dunaway, G. McCarty & L. Sombers

Sources: Crossref, ORCID
Added: January 18, 2021

2020 journal article

Interpreting Dynamic Interfacial Changes at Carbon Fiber Microelectrodes Using Electrochemical Impedance Spectroscopy

Langmuir, 36(15), 4214–4223.

By: C. Meunier, J. Denison, G. McCarty & L. Sombers

Sources: Web Of Science, ORCID, Crossref
Added: May 8, 2020

2020 article

Simultaneous voltammetric detection of glucose and lactate fluctuations in rat striatum evoked by electrical stimulation of the midbrain

ANALYTICAL AND BIOANALYTICAL CHEMISTRY.

By: A. Forderhase, H. Styers, C. Lee & L. Sombers

Sources: Web Of Science, ORCID
Added: August 3, 2020

2019 journal article

Drift Subtraction for Fast-Scan Cyclic Voltammetry Using Double-Waveform Partial-Least-Squares Regression

Analytical Chemistry, 91(11), 7319–7327.

By: C. Meunier, G. McCarty & L. Sombers

Sources: Web Of Science, ORCID, Crossref
Added: June 24, 2019

2018 journal article

Carbon-Fiber Microbiosensor for Monitoring Rapid Lactate Fluctuations in Brain Tissue Using Fast-Scan Cyclic Voltammetry

Analytical Chemistry, 90(21), 12994–12999.

By: S. Smith, S. Gosrani, C. Lee, G. McCarty & L. Sombers

Sources: NC State University Libraries, ORCID, Crossref
Added: November 26, 2018

2018 journal article

Characterization of a Multiple-Scan-Rate Voltammetric Waveform for Real-Time Detection of Met-Enkephalin

ACS Chemical Neuroscience, 10(4), 2022–2032.

By: S. Calhoun, C. Meunier, C. Lee, G. McCarty & L. Sombers

Sources: Web Of Science, ORCID, Crossref
Added: May 6, 2019

2018 journal article

Electrochemical Selectivity Achieved Using a Double Voltammetric Waveform and Partial Least Squares Regression: Differentiating Endogenous Hydrogen Peroxide Fluctuations from Shifts in pH

Analytical Chemistry, 90(3), 1767–1776.

By: C. Meunier, E. Mitchell, J. Roberts, J. Toups, G. McCarty & L. Sombers

Sources: Crossref, ORCID
Added: December 11, 2020

2018 article

Fast-scan cyclic voltammetry: Chemical sensing in the brain and beyond

Analytical Chemistry, Vol. 90, pp. 490–504.

By: J. Roberts & L. Sombers

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2018 journal article

Local μ-Opioid Receptor Antagonism Blunts Evoked Phasic Dopamine Release in the Nucleus Accumbens of Rats

ACS Chemical Neuroscience, 10(4), 1935–1940.

By: A. Gómez-A, T. Shnitko, H. Barefoot, E. Brightbill, L. Sombers, S. Nicola, D. Robinson

Sources: Web Of Science, ORCID, Crossref
Added: May 6, 2019

2018 journal article

NMDA Receptor-Dependent Cholinergic Modulation of Mesolimbic Dopamine Cell Bodies: Neurochemical and Behavioral Studies

ACS Chemical Neuroscience, 10(3), 1497–1505.

By: M. Spanos, X. Xie, J. Gras-Najjar, S. White & L. Sombers

Sources: Web Of Science, ORCID, Crossref
Added: April 9, 2019

2018 journal article

Quantitative Comparison of Enzyme Immobilization Strategies for Glucose Biosensing in Real-Time Using Fast-Scan Cyclic Voltammetry Coupled with Carbon-Fiber Microelectrodes

ChemPhysChem, 19(10), 1197–1204.

By: S. Smith, L. Lugo-Morales, C. Tang, S. Gosrani, C. Lee, J. Roberts, S. Morton, G. McCarty, S. Khan, L. Sombers

Sources: Crossref, ORCID
Added: December 11, 2020

2018 journal article

Reducing Data Density in Fast-Scan Cyclic Voltammetry Measurements of Dopamine Dynamics

Journal of The Electrochemical Society, 165(12), G3042–G3050.

By: C. Lee, L. Qi, A. Amos, K. Blanton, G. McCarty & L. Sombers

Sources: Crossref, ORCID
Added: January 18, 2021

2017 journal article

Background signal as an in situ predictor of dopamine oxidation potential: Improving interpretation of fast-scan cyclic voltammetry data

ACS Chemical Neuroscience, 8(2), 411–419.

By: C. Meunier, J. Roberts, G. McCarty & L. Sombers

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

Selective and Mechanically Robust Sensors for Electrochemical Measurements of Real-Time Hydrogen Peroxide Dynamics in Vivo

Analytical Chemistry, 90(1), 888–895.

By: L. Wilson, S. Panda, A. Schmidt & L. Sombers

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Simultaneous Voltammetric Measurements of Glucose and Dopamine Demonstrate the Coupling of Glucose Availability with Increased Metabolic Demand in the Rat Striatum

ACS Chemical Neuroscience, 8(2), 272–280.

By: S. Smith, C. Lee, M. Dausch, B. Horman, H. Patisaul, G. McCarty, L. Sombers

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Spectroelectrochemical Characterization of the Dynamic Carbon-Fiber Surface in Response to Electrochemical Conditioning

Langmuir, 33(32), 7838–7846.

By: E. Mitchell, L. Dunaway, G. McCarty & L. Sombers

Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2016 journal article

The Hydroxyl radical is a critical intermediate in the voltammetric detection of hydrogen peroxide

Journal of the American Chemical Society, 138(8), 2516–2519.

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Unmasking the effects of L-DOPA on rapid dopamine signaling with an improved approach for nafion coating carbon-fiber microelectrodes

Analytical Chemistry, 88(16), 8129–8136.

By: L. Qi, E. Thomas, S. White, S. Smith, C. Lee, L. Wilson, L. Sombers

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2015 journal article

Enzyme-based microbiosensors for selective quantification of rapid molecular fluctuations in brain tissue

Compendium of In Vivo Monitoring in Real-Time Molecular Neuroscience, Vol 1: Fundamentals and Applications, 137–160.

By: L. Lugo-Morales & L. Sombers

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Multiple scan rate voltammetry for selective quantification of real-time enkephalin dynamics

Analytical Chemistry, 86(15), 7806–7812.

By: A. Schmidt, L. Dunaway, J. Roberts, G. McCarty & L. Sombers

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Peroxygenase and oxidase activities of dehaloperoxidase-hemoglobin from Amphitrite ornata

Journal of the American Chemical Society, 136(22), 7914–7925.

By: D. Barrios, J. D'Antonio, N. McCombs, J. Zhao, S. Franzen, A. Schmidt, L. Sombers, R. Ghiladi

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Reducing the sampling rate of biochemical measurements using fast-scan cyclic voltammetry for in vivo applications

IEEE Sensors Journal, 14(9), 2975–2980.

By: A. Amos, J. Roberts, L. Qi, L. Sombers & G. McCarty

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2013 journal article

Carbon nanotube yarn electrodes for enhanced detection of neurotransmitter dynamics in live brain tissue

ACS Nano, 7(9), 7864–7873.

By: A. Schmidt, X. Wang, Y. Zhu & L. Sombers

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2013 journal article

Enzyme-modified carbon-fiber microelectrode for the quantification of dynamic fluctuations of nonelectroactive analytes using fast-scan cyclic voltammetry

Analytical Chemistry, 85(18), 8780–8786.

By: L. Lugo-Morales, P. Loziuk, A. Corder, J. Toups, J. Roberts, K. McCaffrey, L. Sombers

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2013 journal article

In situ electrode calibration strategy for voltammetric measurements in vivo

Analytical Chemistry, 85(23), 11568–11575.

By: J. Roberts, J. Toups, E. Eyualem, G. McCarty & L. Sombers

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2013 journal article

Quantitation of hydrogen peroxide fluctuations and their modulation of dopamine dynamics in the rat dorsal striatum using fast-scan cyclic voltammetry

ACS Chemical Neuroscience, 4(5), 782–789.

By: M. Spanos, J. Gras-Najjar, J. Letchworth, A. Sanford, J. Toups & L. Sombers

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2012 chapter

Real-Time Chemical Measurements of Dopamine Release in the Brain

In Methods in Molecular Biology (pp. 275–294).

By: J. Roberts, L. Lugo-Morales, P. Loziuk & L. Sombers

Sources: Crossref, ORCID
Added: February 5, 2021

2012 journal article

Sources contributing to the average extracellular concentration of dopamine in the nucleus accumbens

Journal of Neurochemistry, 121(2), 252–262.

By: C. Owesson-White, M. Roitman, L. Sombers, A. Belle, R. Keithley, J. Peele, R. Carelli, R. Wightman

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2012 journal article

Trace metal complexation by the triscatecholate siderophore protochelin: structure and stability

Biometals, 25(2), 393–412.

By: J. Harrington, J. Bargar, A. Jarzecki, J. Roberts, L. Sombers & O. Duckworth

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2011 journal article

Comparison of electrode materials for the detection of rapid hydrogen peroxide fluctuations using background-subtracted fast scan cyclic voltammetry

The Analyst, 136(17), 3550.

By: J. Roberts, K. Hamilton & L. Sombers

Sources: NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2010 conference paper

Application of Fast-Scan Cyclic Voltammetry to Monitoring Endogenous Hydrogen Peroxide Fluctuations In Vivo

In B. Westerink, R. Clinckers, I. Smolders, S. Sarre, & Y. Michotte (Eds.), Monitoring Molecules in Neuroscience (pp. 89–91). Brussels, Belgium: Vrije Universiteit.

By: A. Sanford, J. Letchworth & L. Sombers

Ed(s): B. Westerink, R. Clinckers, I. Smolders, S. Sarre & Y. Michotte

Event: 13th International Conference on In Vivo Methods at Brussels, Belgium on September 12-16, 2010

Source: NC State University Libraries
Added: February 12, 2021

2010 journal article

Specific oxygen-containing functional groups on the carbon surface underlie an enhanced sensitivity to dopamine at electrochemically pretreated carbon fiber microelectrodes

Langmuir, 26(11), 9116–9122.

By: J. Roberts, B. Moody, G. McCarty & L. Sombers

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2010 journal article

Voltammetric detection of hydrogen peroxide at carbon fiber microelectrodes

Analytical Chemistry, 82(12), 5205–5210.

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2009 journal article

Synaptic Overflow of Dopamine in the Nucleus Accumbens Arises from Neuronal Activity in the Ventral Tegmental Area

Journal of Neuroscience, 29(6), 1735–1742.

By: L. Sombers, M. Beyene, R. Carelli & R. Mark Wightman

Sources: Crossref, ORCID
Added: February 6, 2021

2008 journal article

Dopamine Detection with Fast-Scan Cyclic Voltammetry Used with Analog Background Subtraction

Analytical Chemistry, 80(11), 4040–4048.

By: A. Hermans, R. Keithley, J. Kita, L. Sombers & R. Wightman

Sources: Crossref, ORCID
Added: August 28, 2020

2007 journal article

Dopamine release is heterogeneous within microenvironments of the rat nucleus accumbens

European Journal of Neuroscience, 26(7), 2046–2054.

By: R. Wightman, M. Heien, K. Wassum, L. Sombers, B. Aragona, A. Khan, J. Ariansen, J. Cheer, P. Phillips, R. Carelli

Sources: Crossref, ORCID
Added: February 6, 2021

2007 journal article

High Osmolarity andL-DOPA Augment Release via the Fusion Pore in PC12 Cells

ChemPhysChem, 8(17), 2471–2477.

By: L. Sombers, N. Wittenberg, M. Maxson, K. Adams & A. Ewing

Sources: Crossref, ORCID
Added: August 28, 2020

2007 journal article

Multicore Vesicles: Hyperosmolarity and l-DOPA Induce Homotypic Fusion of Dense Core Vesicles

Cellular and Molecular Neurobiology, 27(5), 681–685.

By: L. Sombers, M. Maxson & A. Ewing

Sources: Crossref, ORCID
Added: August 28, 2020

2007 journal article

Phasic Dopamine Release Evoked by Abused Substances Requires Cannabinoid Receptor Activation

Journal of Neuroscience, 27(4), 791–795.

By: J. Cheer, K. Wassum, L. Sombers, M. Heien, J. Ariansen, B. Aragona, P. Phillips, R. Wightman

Sources: Crossref, ORCID
Added: February 6, 2021

2006 conference paper

Burst Firing of Midbrain Dopamine Neurons Contributes to Transient Dopamine Fluctuations Time-Locked to Behavioral Responses in the Nucleus Accumbens of Freely-Moving Rats

In G. Di Chiara, E. Carboni, V. Valentini, E. Acquas, V. Bassareo, & C. Cadoni (Eds.), Monitoring molecules in neuroscience: proceeding of the 11.th International conference on in Vivo Methods 2006 : University of Cagliari, Italy (pp. 560–562). Italy: Grafiche Sainas.

By: L. Sombers, M. Beyene, J. Ariansen, C. Owesson White, J. Cheer & R. Wightman

Ed(s): G. Di Chiara, E. Carboni, V. Valentini, E. Acquas, V. Bassareo & C. Cadoni

Event: 11th International Conference on In Vivo Methods at Cagliari, Sardinia, Italy on May 19-22, 2006

Source: NC State University Libraries
Added: February 12, 2021

2005 journal article

Correlation between Vesicle Quantal Size and Fusion Pore Release in Chromaffin Cell Exocytosis

Biophysical Journal, 88(6), 4411–4420.

By: C. Amatore, S. Arbault, I. Bonifas, Y. Bouret, M. Erard, A. Ewing, L. Sombers

Sources: Crossref, ORCID
Added: February 5, 2021

2005 journal article

Loaded dopamine is preferentially stored in the halo portion of PC12 cell dense core vesicles

Journal of Neurochemistry, 93(5), 1122–1131.

By: L. Sombers, M. Maxson & A. Ewing

Sources: Crossref, ORCID
Added: February 6, 2021

2004 journal article

The Effects of Vesicular Volume on Secretion through the Fusion Pore in Exocytotic Release from PC12 Cells

Journal of Neuroscience, 24(2), 303–309.

By: L. Sombers

Sources: Crossref, ORCID
Added: February 5, 2021

2004 chapter

The Modulation of Vesicular Volume and its Effect on Neurotransmitter Secretion through the Fusion Pore in PC12 Cells

In R. Borges & L. Gandia (Eds.), Cell Biology of the Chromaffin Cell (pp. 43–46). Spain: Instituto Teófilo Hernando.

By: L. Sombers, H. Hanchar, T. Colliver, N. Wittenberg, A. Cans, S. Arbault, C. Amatore, A. Ewing

Ed(s): R. Borges & L. Gandia

Source: NC State University Libraries
Added: February 12, 2021

2003 conference paper

Amperometric Detection of Exocytosis at Cells and Artificial Cells

In J. Kehr, K. Fuxe, U. Ungerstedt, & T. Svensson (Eds.), Monitoring molecules in neuroscience : proceedings of the 10th International Conference on In Vivo Methods : Karolinska Institutet, Stockholm, Sweden June 24-27, 2003 (pp. 171–173). Stockholm, Sweden: Karolinska University Press.

By: A. Ewing, A. Cans, L. Sombers, N. Wittenberg, D. Eves, R. Karlsson, M. Karlsson, A. Karlsson, O. Orwar

Ed(s): J. Kehr, K. Fuxe, U. Ungerstedt & T. Svensson

Event: 10th International Conference on In Vivo Methods at Stockholm, Sweden on June 24-27, 2003

Source: NC State University Libraries
Added: February 12, 2021

2003 journal article

Artificial cells: Unique insights into exocytosis using liposomes and lipid nanotubes

Proceedings of the National Academy of Sciences, 100(2), 400–404.

By: A. Cans, N. Wittenberg, R. Karlsson, L. Sombers, M. Karlsson, O. Orwar, A. Ewing

Sources: Crossref, ORCID
Added: February 5, 2021

2003 conference paper

Vesicular Volume, the Fusion Pore and Potential ‘Presynaptic’ Mechanisms Modulating Neurotransmitter Release

In J. Kehr, K. Fuxe, U. Ungerstedt, & T. Svensson (Eds.), Monitoring molecules in neuroscience : proceedings of the 10th International Conference on In Vivo Methods : Karolinska Institutet, Stockholm, Sweden June 24-27, 2003 (pp. 189–191). Stockholm, Sweden: Karolinska University Press.

By: L. Sombers, M. Maxson & A. Ewing

Ed(s): J. Kehr, K. Fuxe, U. Ungerstedt & T. Svensson

Event: 10th International Conference on In Vivo Methods at Stockholm, Sweden on June 24-27, 2003

Source: NC State University Libraries
Added: February 12, 2021

2002 journal article

Differentiated PC12 Cells

Annals of the New York Academy of Sciences, 971(1), 86–88.

By: L. Sombers, T. Colliver & A. Ewing

Sources: Crossref, ORCID
Added: February 5, 2021

2002 chapter

Electrochemical Monitoring of Exocytosis from Individual PC12 Cells in Culture

In A. Brajter-Toth & J. Q. Chambers (Eds.), Electroanalytical Methods for Biological Materials (pp. 279–327).

By: L. Sombers & A. Ewing

Ed(s): A. Brajter-Toth & J. Chambers

Sources: Crossref, ORCID
Added: February 6, 2021

2001 chapter

Electrochemical or Separations-Based Sensing of Neurotransmitter Dynamics and Storage at Cells and Varicosities in Culture

In W. T. O'Connor, J. P. Lowry, J. J. O'Connor, & R. D. O'Neill (Eds.), Monitoring molecules in neuroscience : proceedings of the 9th International Conference on In Vivo Methods, June 16-19, 2001, University College Dublin, Ireland (pp. 57–58). Dublin: University College Dublin.

By: A. Ewing, L. Sombers, L. Woods, T. Colliver, M. Achalabun, K. Moran, J. Lapos, T. Paxon, A. Cans

Ed(s): W. O'Connor, J. Lowry, J. O'Connor & R. O'Neill

Event: 9th International Conference on In Vivo Methods at Dublin, Ireland on June 16-19, 2001

Source: NC State University Libraries
Added: February 12, 2021