Luke B Borst

Development and Application of Optimized Isolation Methods and Diagnostic PCR Protocols for the Detection of Pathogenic Enterococcus cecorum Isolated from Broiler Chickens

Suyemoto, M. M., Walker, G. K., Taldo, U., Diveley, K. R., & Borst, L. B. (2025, February 13). Avian Diseases, Vol. 2.

Canine uropathogenic and avian pathogenic Escherichia coli harboring conjugative plasmids exhibit augmented growth and exopolysaccharide production in response to Enterococcus faecalis

PLOS ONE, 19(11), e0312732.

Pharmacokinetics of pradofloxacin, florfenicol, and tulathromycin and response to treatment of steers experimentally infected with Mannheimia hemolytica

Foster, D. M., Halleran, J. L., Jacob, M. E., Hempstead, S., Borst, L. B., Watanabe, T. T. N., … Papich, M. G. (2024, December 10). Journal of Veterinary Internal Medicine, Vol. 39.

Draft Genome Sequences of Escherichia coli and Enterococcus faecalis Coisolated from Polymicrobial Extraintestinal Infections of Chickens and Turkeys

Microbiology Resource Announcements, 12(3).

Draft genome sequences of 12 Escherichia coli co-isolated with Enterococcus spp. from dogs with polybacterial bacteriuria at a veterinary hospital

Walker, G. K., Harden, L., Suyemoto, M. M., Thakur, S., Jacob, M., & Borst, L. B. (2023, August 8). Microbiology Resource Announcements, Vol. 8.

Pancreatic Torsion Resulting in Acute Pancreatic Necrosis in a Young Dog

Multani, R., Cohen, E. B., Haas, J., Borst, L., Womble, M., & Musulin, S. (2023, October 26). Journal of the American Animal Hospital Association, Vol. 59, pp. 297–301.

Allogeneic and xenogeneic lymphoid reconstitution in a RAG2−/−IL2RGy/− severe combined immunodeficient pig: A preclinical model for intrauterine hematopoietic transplantation

Sper, R. B., Proctor, J., Lascina, O., Guo, L., Polkoff, K., Kaeser, T., … Piedrahita, J. A. (2022, October 14). Frontiers in Veterinary Science, Vol. 10.

Cranial internal hemipelvectomy (iliectomy) with limb sparing for a dog with ilial chondrosarcoma: A case report

Clinical Case Reports, 10(1).

Detection of Escherichia coli and Enterococcus spp. in dogs with polymicrobial urinary tract infections: A 5‐year retrospective study

Journal of Veterinary Internal Medicine, 36(4), 1322–1329.

Pathology in Practice

Bauer, K., Murillo, D. F. B., Schreeg, M. E., Borst, L. B., & Watanabe, T. T. N. (2022, May 4). Journal of the American Veterinary Medical Association, Vol. 260, pp. 1466–1468.

A Zebrafish Model of Metastatic Colonization Pinpoints Cellular Mechanisms of Circulating Tumor Cell Extravasation

Allen, T. A., Cullen, M. M., Hawkey, N., Mochizuki, H., Nguyen, L., Schechter, E., … Somarelli, J. A. (2021, September 23). Frontiers in Oncology, Vol. 9.

Genomic Characterization of a Nalidixic Acid-Resistant Salmonella Enteritidis Strain Causing Persistent Infections in Broiler Chickens

Walker, G. K., Suyemoto, M. M., Hull, D. M., Gall, S., Jimenez, F., Chen, L. R., … Borst, L. B. (2021, September 1). Frontiers in Veterinary Science, Vol. 9.

Creation of a Continent Urinary Bladder Reservoir Vascularized by Omentum as a Possible Surgical Option for Canine Trigonal/Urethral Urothelial Carcinoma

Journal of Investigative Surgery, 35(3), 481–495.

Development of a Genome-Wide Oligonucleotide Microarray Platform for Detection of DNA Copy Number Aberrations in Feline Cancers

Thomas, R., Pontius, J. U., Borst, L. B., & Breen, M. (2020, July 7). Veterinary Sciences, Vol. 7.

Personalized‐induced neural stem cell therapy: Generation, transplant, and safety in a large animal model

Bomba, H. N., Sheets, K. T., Valdivia, A., Khagi, S., Ruterbories, L., Mariani, C. L., … Hingtgen, S. D. (2020, July 1). Bioengineering & Translational Medicine.

Plasma metabolomic profiling of healthy pregnant mares and mares with experimentally induced placentitis

Equine Veterinary Journal, 53(1), 85–93.

Research Note: Repetitive element–based polymerase chain reaction genotyping improves efficiency of Salmonella surveillance in a model broiler production system

Poultry Science, 99(5), 2684–2689.

The role of Enterococcus faecalis during co-infection with avian pathogenic Escherichia coli in avian colibacillosis

Avian Pathology, 49(6), 589–599.

Allantoic Metabolites, Progesterone, and Estradiol-17β Remain Unchanged After Infection in an Experimental Model of Equine Ascending Placentitis

Journal of Equine Veterinary Science., 2. http://europepmc.org/abstract/AGR/IND606255595

Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma

Megquier, K., Turner-Maier, J., Swofford, R., Kim, J.-H., Sarver, A. L., Wang, C., … Lindblad-Toh, K. (2019, September 30). Molecular Cancer Research, Vol. 17, pp. 2410–2421.

Genomic analysis reveals shared genes and pathways in human and canine angiosarcoma

Megquier, K., Turner-Maier, J., Swofford, R., Kim, J.-H., Sarver, A. L., Wang, C., … Lindblad-Toh, K. (2019, March 8).

Immune dysregulation and osteosarcoma: Staphylococcus aureus downregulates TGF‐β and heightens the inflammatory signature in human and canine macrophages suppressed by osteosarcoma

Tuohy, J. L., Somarelli, J. A., Borst, L. B., Eward, W. C., Lascelles, B. D. X., & Fogle, J. E. (2019, August 17). Veterinary and Comparative Oncology, Vol. 8.

Sensitization of Vascular Endothelial Cells to Ionizing Radiation Promotes the Development of Delayed Intestinal Injury in Mice

Lee, C.-L., Daniel, A. R., Holbrook, M., Brownstein, J., Campos, L. D. S., Hasapis, S., … Kirsch, D. G. (2019, July 2). Radiation Research, Vol. 7.

Temporal characterization of wooden breast myopathy (“woody breast”) severity and correlation with growth rate and lymphocytic phlebitis in three commercial broiler strains and a random-bred broiler strain

Chen, L. R., Suyemoto, M. M., Sarsour, A. H., Cordova, H. A., Oviedo-Rondón, E. O., Wineland, M., … Borst, L. B. (2019, March 27). Avian Pathology.

Wooden Breast in Commercial Broilers Associated with Mortality, Dorsal Recumbency, and Pulmonary Disease

Gall, S., Suyemoto, M. M., Sather, H. M. L., Sharpton, A. R., Barnes, H. J., & Borst, L. B. (2019, April 29). Avian Diseases, Vol. 63, pp. 514–519.

A Review ofEnterococcus cecorumInfection in Poultry

Jung, A., Chen, L. R., Suyemoto, M. M., Barnes, H. J., & Borst, L. B. (2018, September 1). Avian Diseases, Vol. 9.

Allantoic Metabolites, Progesterone, and Estradiol-17β Remain Unchanged After Infection in an Experimental Model of Equine Ascending Placentitis

Beachler, T., Gracz, H., Long, N. M., Borst, L., Morgan, D., Nebel, A., … Bailey, C. S. (2018, November 29). Journal of Equine Veterinary Science, Vol. 73, pp. 95–105.

Assessment of a novel nanoparticle hyperthermia therapy in a murine model of osteosarcoma

Vet Surg, 47(8), 1021–1030.

Coinfection with Eimeria spp. decreases bacteremia and spinal lesions caused by pathogenic Enterococcus cecorum

Animal Feed Science and Technology, 250, 59–68.

Gross Morphometry, Histomorphometry, and Immunohistochemistry Confirm Early and Persistent Jejunal Crypt Hyperplasia in Poults with Enteritis and Depressed Growth

Avian Diseases, 62(2), 163–170.

Lameness in a 3-year-old backyard chicken Response

Mast Cells Exert Anti-Inflammatory Effects in an IL10^−/−Model of Spontaneous Colitis

Lennon, E. M., Borst, L. B., Edwards, L. L., & Moeser, A. J. (2018, January 1). Mediators of Inflammation.

Mast Cells Play a Protective Role in Spontaneous Colitis

Journal of Immunology, 200(Supplement 1).

Mast cells exert anti-inflammatory effects in an IL10(-/-) model of spontaneous colitis

Mediators of Inflammation.

Sleep hygiene among veterinary medical students

Royal, K. D., Hunt, S. A., Borst, L. B., & Gerard, M. (2018, January 1). Journal of Education and Health Promotion.

Vaccination of breeder hens with a polyvalent killed vaccine for pathogenicEnterococcus cecorumdoes not protect offspring from enterococcal spondylitis

Borst, L. B., Suyemoto, M. M., Chen, L. R., & Barnes, H. J. (2018, October 17). Avian Pathology, Vol. 48, pp. 17–24.

What Is Your Diagnosis?

Almeida, S. M. B., Shive, H. R., Harvey, J. B., Borst, L. B., & Cohen, E. B. (2018, January 10). Journal of the American Veterinary Medical Association, Vol. 252, pp. 173–175.

Dietary Prebiotics and Arachidonic Acid (ARA) Modulate Intestinal Injury and Microbial Taxa Following Acute Dextran Sodium Sulfate Induced Colitis in Formula-Fed Piglets

The FASEB Journal, 31(1_supplement), 324–324.

Prevalence and severity of osteochondrosis of the free thoracic vertebra in three modern broiler strains and the Athens Canadian Random Bred control broiler

Avian Pathology, 47(2), 152–160.

A Comprehensive Wellness Program for Veterinary Medical Education: Design and Implementation at North Carolina State University

International Journal of Higher Education, 6(1), 74.

Alternative lengthening of telomeres does exist in various canine sarcomas

Kreilmeier, T., Sampl, S., Deloria, A. J., Walter, I., Reifinger, M., Hauck, M., … Kleiter, M. (2016, September 1). Molecular Carcinogenesis, Vol. 3.

Culture methods impact recovery of antibiotic-resistant Enterococci includingEnterococcus cecorumfrom pre- and postharvest chicken

Suyemoto, M. M., Barnes, H. J., & Borst, L. B. (2016, December 17). Letters in Applied Microbiology, Vol. 64, pp. 210–216.

Dietary Iron Deficiency and Oversupplementation Increase Intestinal Permeability, Ion Transport, and Inflammation in Pigs

Li, Y., Hansen, S. L., Borst, L. B., Spears, J. W., & Moeser, A. J. (2016, June 30). Journal of Nutrition, Vol. 146, pp. 1499–1505.

Extreme lymphocytosis with myelomonocytic morphology in a horse with diffuse large B-cell lymphoma

Veterinary Clinical Pathology, 46(1), 64–71.

Immunohistochemistry

In Tumors in Domestic Animals (pp. 44–87).

Integrated immunohistochemical and DNA copy number profiling analysis provides insight into the molecular pathogenesis of canine follicular lymphoma

Thomas, R., Demeter, Z., Kennedy, K. A., Borst, L., Singh, K., Valli, V. E., … Breen, M. (2016, May 2). Veterinary and Comparative Oncology, Vol. 15, pp. 852–867.

Pamidronate functionalized nanoconjugates for targeted therapy of focal skeletal malignant osteolysis

Yin, Q., Tang, L., Cai, K., Tong, R., Sternberg, R., Yang, X., … Fan, T. M. (2016, July 25). Proceedings of the National Academy of Sciences, Vol. 113, pp. E4601–4609.

Pathogenesis of Enterococcal Spondylitis Caused by Enterococcus cecorum in Broiler Chickens

Veterinary Pathology, 54(1), 61–73.

Pathology in Practice

Meichner, K., Montgomery, S. A., Borst, L. B., Murphy, K. M., & Grindem, C. B. (2016, October 21). Journal of the American Veterinary Medical Association, Vol. 249, pp. 1023–1026.

Scavenging nucleic acid debris to combat autoimmunity and infectious disease

Holl, E. K., Shumansky, K. L., Borst, L. B., Burnette, A. D., Sample, C. J., Ramsburg, E. A., & Sullenger, B. A. (2016, August 15). Proceedings of the National Academy of Sciences, Vol. 113, pp. 9728–9733.

Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma

Lee, C. L., Castle, K. D., Moding, E. J., Blum, J. M., Williams, N., Luo, L., … al. (2015, September 24). Nature Communications, Vol. 9.

Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma

Nature Communications, 6.

Acute Dextran Sodium Sulfate Dose-Dependently Induces Colitis in Formula-Fed Piglets

The FASEB Journal, 29(Supplement 1), 755–758.

Comparative Genomic Analysis Identifies Divergent Genomic Features of Pathogenic Enterococcus cecorum Including a Type IC CRISPR-Cas System, a Capsule Locus, an epa-Like Locus, and Putative Host Tissue Binding Proteins

Borst, L. B., Suyemoto, M. M., Scholl, E. H., Fuller, F. J., & Barnes, H. J. (2015, April 10). PLoS ONE, Vol. 10.

Cytologic Characteristics and World Health Organization Classification in 45 Dogs With Lymphoma

Veterinary Clinical Pathology, 44(4).

Early-life dietary spray-dried plasma influences immunological and intestinal injury responses to later-lifeSalmonellatyphimuriumchallenge

British Journal of Nutrition, 113(5), 783–793.

Enterococcus faecalis Gelatinase Mediates Intestinal Permeability via Protease-Activated Receptor 2

Maharshak, N., Huh, E. Y., Paiboonrungruang, C., Shanahan, M., Thurlow, L., Herzog, J., … Carroll, I. M. (2015, April 28). Infection and Immunity, Vol. 83, pp. 2762–2770.

Histiocytic Sarcoma with Central Nervous System Involvement in Dogs: 19 Cases (2006-2012)

Journal of Veterinary Internal Medicine, 29(2), 607–613.

Targeting Tumor Vasculature with Aptamer-Functionalized Doxorubicin–Polylactide Nanoconjugates for Enhanced Cancer Therapy

Tang, L., Tong, R., Coyle, V. J., Yin, Q., Pondenis, H., Borst, L. B., … Fan, T. M. (2015, May 4). ACS Nano, Vol. 9, pp. 5072–5081.

What’s your diagnosis? Purulent upper respiratory discharge in a rabbit

DVM 360. https://www.dvm360.com/view/whats-your-diagnosis-purulent-upper-respiratory-discharge-rabbit

A Chicken Embryo Lethality Assay for PathogenicEnterococcus cecorum

Borst, L. B., Suyemoto, M. M., Keelara, S., Dunningan, S. E., Guy, J. S., & Barnes, H. J. (2014, June 1). Avian Diseases, Vol. 58, pp. 244–248.

Antimicrobial resistance, virulence determinants and genetic profiles of clinical and nonclinical E nterococcus cecorum from poultry

Jackson, C. R., Kariyawasam, S., Borst, L. B., Frye, J. G., Barrett, J. B., Hiott, L. M., & Woodley, T. A. (2014, December 3). Letters in Applied Microbiology, Vol. 60, pp. 111–119.

Comparative cytogenetic characterization of primary canine melanocytic lesions using array CGH and fluorescence in situ hybridization

Poorman, K., Borst, L., Moroff, S., Roy, S., Labelle, P., Motsinger-Reif, A., & Breen, M. (2014, December 15). Chromosome Research, Vol. 23, pp. 171–186.

Dual Small-Molecule Targeting of Procaspase-3 Dramatically Enhances Zymogen Activation and Anticancer Activity

Botham, R. C., Fan, T. M., Im, I., Borst, L. B., Dirikolu, L., & Hergenrother, P. J. (2014, January 3). Journal of the American Chemical Society, Vol. 136, pp. 1312–1319.

Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma

Thomas, R., Borst, L., Rotroff, D., Motsinger-Reif, A., Lindblad-Toh, K., Modiano, J. F., & Breen, M. (2014, March 5). Chromosome Research, Vol. 22, pp. 305–319.

Innate PI3K p110δ Regulates Th1/Th17 Development and Microbiota-Dependent Colitis

Steinbach, E. C., Kobayashi, T., Russo, S. M., Sheikh, S. Z., Gipson, G. R., Kennedy, S. T., … Plevy, S. E. (2014, March 15). The Journal of Immunology, Vol. 192, pp. 3958–3968.

Investigating the optimal size of anticancer nanomedicine

Tang, L., Yang, X., Yin, Q., Cai, K., Wang, H., Chaudhury, I., … Cheng, J. (2014, October 14). Proceedings of the National Academy of Sciences, Vol. 111, pp. 15344–15349.

Mo1722 Mast Cells Play a Protective Role in Spontaneous Colitis

Gastroenterology, 146(5), S-644.

NFIL3-Deficient Mice Develop Microbiota-Dependent, IL-12/23–Driven Spontaneous Colitis

Kobayashi, T., Steinbach, E. C., Russo, S. M., Matsuoka, K., Nochi, T., Maharshak, N., … Plevy, S. E. (2014, January 18). The Journal of Immunology, Vol. 192, pp. 1918–1927.

Pro-tumorigenic Effects of Transforming Growth Factor Beta 1 in Canine Osteosarcoma

Portela, R. F., Fadl-Alla, B. A., Pondenis, H. C., Byrum, M. L., Garrett, L. D., Wycislo, K. L., … Fan, T. M. (2014, March 31). Journal of Veterinary Internal Medicine, Vol. 28, pp. 894–904.

Biological behaviour of canine mandibular osteosarcoma. A retrospective study of 50 cases (1999–2007)

Coyle, V. J., Rassnick, K. M., Borst, L. B., Rodriguez, C. O., Northrup, N. C., Fan, T. M., & Garrett, L. D. (2013, February 15). Veterinary and Comparative Oncology, Vol. 13, pp. 89–97.

Bone marrow-derived cells participate in the formation of normal and neoplastic lung stroma.

Anticancer Research, 3(3), 831–836. http://europepmc.org/abstract/med/23482751

Characterization of BcaA, a Putative Classical Autotransporter Protein in Burkholderia pseudomallei

Campos, C. G., Borst, L., & Cotter, P. A. (2013, January 23). Infection and Immunity, Vol. 81, pp. 1121–1128.

Chronic Compressive Myelopathy and Progressive Neurologic Signs Associated with Melarsomine Dihydrochloride Administration in a Dog

Moore, S. A., Mariani, C. L., Wettere, A. V., & Borst, L. B. (2013, January 1). Journal of the American Animal Hospital Association, Vol. 49, pp. 389–393.

Discovery of a Bovine Enterovirus in Alpaca

McClenahan, S. D., Scherba, G., Borst, L., Fredrickson, R. L., Krause, P. R., & Uhlenhaut, C. (2013, August 12). PLoS ONE.

Distribution of K and L cells in the feline intestinal tract

Gilor, C., Gilor, S., Graves, T. K., Borst, L. B., Labelle, P., Ridge, T. K., … Dossin, O. (2013, May 18). Domestic Animal Endocrinology, Vol. 7.

Early Life Stress Triggers Persistent Colonic Barrier Dysfunction and Exacerbates Colitis in Adult IL-10−/− Mice

Lennon, E. M., Maharshak, N., Elloumi, H., Borst, L., Plevy, S. E., & Moeser, A. J. (2013, February 27). Inflammatory Bowel Diseases, Vol. 19, pp. 712–719.

Evaluation of the effects of tricaine methanesulfonate on retinal structure and function in koi carp (Cyprinus carpio)

Journal of the American Veterinary Medical Association, 242(11), 1578–1582.

Extrauterine Listeriosis in the Gravid Mouse Influences Embryonic Growth and Development

PLoS ONE, 8(8), e72601.

Extrauterine Listeriosis in the gravid mouse influences embryonic growth and development

PLoS One, 8(8).

GI-9 Mortality In Foster-Age Kittens Is Associated With A Shift From Ileum Mucosa-Associated Enterococcus Hirae to Colonization By E. Faecalis and Enteropathogenice E. Coli

Journal of Veterinary Internal Medicine, 27(3), 698.

Gene Profiling of Canine B-Cell Lymphoma Reveals Germinal Center and Postgerminal Center Subtypes with Different Survival Times, Modeling Human DLBCL

Cancer Research, 73(16), 5029–5039.