Works (48)

Updated: February 16th, 2024 05:00

2024 journal article

Myeloid cell MHC I expression drives CD8+ T cell activation in nonalcoholic steatohepatitis

FRONTIERS IN IMMUNOLOGY, 14.

By: V. Adams n, L. Collins n, T. Williams n, J. Holmes n, P. Hess n, H. Atkins n, G. Scheidemantle n, X. Liu n ...

co-author countries: United States of America 🇺🇸

Contributors: T. Williams n, V. Adams n, L. Collins n, J. Holmes n, P. Hess n, H. Atkins n, G. Scheidemantle n, X. Liu n ...

Ed(s): T. Williams n, L. Collins n & A. Kennedy n

author keywords: liver; NASH; fibrosis; H2Kb; CD8(+) T cells; immunopeptidome
Sources: Web Of Science, ORCID
Added: January 28, 2024

2023 article

A bottom-up proteomics workflow for a system containing multiple organisms

Bai, H., Collins, L. B. B., Andre, M. R., Breitschwerdt, E. B. B., & Williams, T. I. (2023, January 3). RAPID COMMUNICATIONS IN MASS SPECTROMETRY, Vol. 1.

By: H. Bai n, L. Collins n, M. Andre n, E. Breitschwerdt n & T. Williams n

co-author countries: United States of America 🇺🇸

Contributors: H. Bai n, L. Collins n, M. André n, E. Breitschwerdt n & T. Williams n

Sources: Web Of Science, ORCID
Added: November 25, 2022

2023 article

Discovery Proteomics and Absolute Protein Quantification Can Be Performed Simultaneously on an Orbitrap-Based Mass Spectrometer

Williams, T. I., Kowalchyk, C., Collins, L. B., & Reading, B. J. (2023, March 22). ACS OMEGA, Vol. 3.

By: T. Williams n, C. Kowalchyk*, L. Collins n & B. Reading n

co-author countries: United States of America 🇺🇸

Contributors: T. Williams n, C. Kowalchyk*, L. Collins n & B. Reading n

Sources: Web Of Science, ORCID
Added: March 23, 2023

2023 article

Discovery of a Hybrid System for Photocatalytic CO2 Reduction via Attachment of a Molecular Cobalt-Quaterpyridine Complex to a Crystalline Carbon Nitride

McGuigan, S., Tereniak, S. J., Donley, C. L., Smith, A., Jeon, S., Zhao, F., … Maggard, P. A. (2023, October 12). ACS APPLIED ENERGY MATERIALS, Vol. 10.

By: S. McGuigan n, S. Tereniak*, C. Donley*, A. Smith n, S. Jeon*, F. Zhao*, R. Sampaio*, M. Pauly n ...

co-author countries: United States of America 🇺🇸
author keywords: hybrid materials; photocatalysis; carbon nitride; CO2 reduction
Sources: Web Of Science, ORCID
Added: November 20, 2023

2023 journal article

Improving therapeutic protein secretion in the probiotic yeast Saccharomyces boulardii using a multifactorial engineering approach

MICROBIAL CELL FACTORIES, 22(1).

co-author countries: Denmark 🇩🇰 United States of America 🇺🇸
MeSH headings : Saccharomyces cerevisiae / genetics; Saccharomyces cerevisiae / metabolism; Saccharomyces boulardii / genetics; Saccharomyces boulardii / metabolism; Saccharomyces / genetics; Saccharomyces / metabolism; Probiotics / metabolism; Endopeptidases / metabolism
Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 journal article

Pseudo-affinity capture of K. phaffii host cell proteins in flow-through mode: Purification of protein therapeutics and proteomic study

SEPARATION AND PURIFICATION TECHNOLOGY, 326.

By: S. Sripada n, D. Elhanafi*, L. Collins n, T. Williams n, M. Linova*, J. Woodley*, C. Boi, S. Menegatti n

co-author countries: Denmark 🇩🇰 Italy 🇮🇹 United States of America 🇺🇸

Contributors: S. Sripada n, D. Elhanafi*, L. Collins n, T. Williams n, M. Linova*, J. Woodley*, C. Boi, S. Menegatti n

author keywords: Komagataella phaffii; Chromatography; Protein purification; Monoclonal antibodies; Antibody fragment; Proteomics
Sources: Web Of Science, ORCID
Added: October 23, 2023

2023 journal article

Salinity-induced ionoregulatory changes in the gill proteome of the mayfly, Neocloeon triangulifer

ENVIRONMENTAL POLLUTION, 316.

By: S. Orr n, L. Collins n, D. Jima n & D. Buchwalter n

co-author countries: United States of America 🇺🇸
author keywords: Proteomics; Salinity; Mayfly; Gill biology; Ion transport; Osmoregulation
MeSH headings : Animals; Ephemeroptera; Gills / metabolism; Salinity; Proteome / metabolism; Sodium Chloride / metabolism; Proteomics; Calcium Chloride; Water Pollutants, Chemical / metabolism; Aquatic Organisms / metabolism; Sodium-Potassium-Exchanging ATPase / metabolism; Ions / metabolism; Water / metabolism
Sources: Web Of Science, ORCID
Added: January 30, 2023

2022 article

Improving Therapeutic Protein Secretion in the Probiotic YeastSaccharomyces boulardiiusing a Multifactorial Engineering Approach

Durmusoglu, D., Al’Abri, I., Williams, T. I., Collins, L. B., Martínez, J. L., & Crook, N. (2022, December 31). BioRxiv.

co-author countries: Denmark 🇩🇰 United States of America 🇺🇸

Contributors: D. Durmusoglu n, I. Al'Abri n, T. Williams n, L. Collins n, J. Martínez* & N. Crook n

Source: ORCID
Added: January 1, 2023

2022 journal article

Self-sacrificial tyrosine cleavage by an Fe:Mn oxygenase for the biosynthesis of para-aminobenzoate in Chlamydia trachomatis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(39).

By: O. Manley n, H. Phan n, A. Stewart n, D. Mosley n, S. Xue*, L. Cha n, H. Bai n, V. Lightfoot* ...

co-author countries: United States of America 🇺🇸

Contributors: T. Williams n

author keywords: folate biosynthesis; radical transfer; spectroscopy; heterobinuclear cluster
MeSH headings : Bacterial Proteins / metabolism; Chlamydia trachomatis / enzymology; Folic Acid; Iron / metabolism; Manganese / metabolism; Oxygen / metabolism; Oxygenases / metabolism; Tyrosine / metabolism; para-Aminobenzoates / metabolism
Sources: Web Of Science, ORCID
Added: September 21, 2022

2022 article

Towards a standardized multi-tissue decellularization protocol for the derivation of extracellular matrix materials

Biehl, A., Martins, A. M. G. M., Davis, Z. G. G., Sze, D., Collins, L., Mora-Navarro, C., … Freytes, D. O. O. (2022, December 12). BIOMATERIALS SCIENCE, Vol. 12.

co-author countries: Puerto Rico 🇵🇷 United States of America 🇺🇸
MeSH headings : Tissue Engineering / methods; Proteomics; Extracellular Matrix / chemistry; Hydrogels / chemistry; Biocompatible Materials / analysis; Tissue Scaffolds
Sources: Web Of Science, ORCID
Added: January 3, 2023

2022 journal article

Using Proteomic Approaches to Unravel the Response of Ctenocephalides felis felis to Blood Feeding and Infection With Bartonella henselae

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 12.

By: M. Andre n, P. Neupane n, M. Lappin*, B. Herrin*, V. Smith*, T. Williams n, L. Collins n, H. Bai n ...

co-author countries: Brazil 🇧🇷 United States of America 🇺🇸

Contributors: M. André n, P. Neupane n, M. Lappin*, B. Herrin*, V. Smith*, T. Williams n, L. Collins n, H. Bai n ...

author keywords: bartonellosis; cat flea; cat scratch disease; flea-pathogen interface; proteome
MeSH headings : Animals; Bartonella henselae / genetics; Cat Diseases; Cats; Ctenocephalides; Felis; Proteomics; Siphonaptera
Sources: Web Of Science, ORCID
Added: January 29, 2022

2021 journal article

PFOS dominates PFAS composition in ambient fine particulate matter (PM2.5) collected across North Carolina nearly 20 years after the end of its US production

ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS, 23(4), 580–587.

By: J. Zhou*, K. Baumann*, R. Mead*, S. Skrabal*, R. Kieber*, G. Avery*, M. Shimizu*, J. DeWitt* ...

co-author countries: Spain 🇪🇸 United States of America 🇺🇸
MeSH headings : Alkanesulfonic Acids / analysis; Canada; Europe; Fluorocarbons / analysis; North Carolina; Particulate Matter; Tandem Mass Spectrometry
Sources: Web Of Science, ORCID
Added: June 10, 2021

2018 journal article

Coordinated regulation of intracellular pH by two glucose-sensing pathways in yeast

Journal of Biological Chemistry, 293(7), 2318–2329.

By: D. Isom*, S. Page*, L. Collins*, N. Kapolka*, G. Taghon* & H. Dohlman*

co-author countries: United States of America 🇺🇸
MeSH headings : Cytoplasm / chemistry; Cytoplasm / metabolism; Gene Expression Regulation, Fungal; Glucose / metabolism; Hydrogen-Ion Concentration; Monosaccharide Transport Proteins / genetics; Monosaccharide Transport Proteins / metabolism; Proton-Translocating ATPases / genetics; Proton-Translocating ATPases / metabolism; Saccharomyces cerevisiae / chemistry; Saccharomyces cerevisiae / genetics; Saccharomyces cerevisiae / metabolism; Saccharomyces cerevisiae Proteins / genetics; Saccharomyces cerevisiae Proteins / metabolism
Sources: Crossref, ORCID
Added: September 5, 2021

2018 journal article

Development of a hydrophilic interaction liquid chromatography (HILIC) method for the chemical characterization of water-soluble isoprene epoxydiol (IEPOX)-derived secondary organic aerosol

Environmental Science: Processes & Impacts, 20(11), 1524–1536.

co-author countries: Brazil 🇧🇷 United States of America 🇺🇸
MeSH headings : Aerosols / chemistry; Butadienes / chemistry; Catalysis; Chromatography, Liquid / methods; Epoxy Compounds / chemistry; Hemiterpenes / chemistry; Hydrophobic and Hydrophilic Interactions; Isomerism; Particulate Matter / chemistry; Sulfates / chemistry
Sources: Crossref, ORCID
Added: September 5, 2021

2017 journal article

A purified MAA-based ELISA is a useful tool for determining anti-MAA antibody titer with high sensitivity

PLOS ONE, 12(2), e0172172.

By: T. Shimomoto*, L. Collins*, X. Yi*, D. Holley*, Z. Zhang*, X. Tian*, K. Uchida*, C. Wang* ...

co-author countries: Finland 🇫🇮 Japan 🇯🇵 United States of America 🇺🇸

Ed(s): C. Hagemeyer

MeSH headings : Acetaldehyde / immunology; Animals; Autoantibodies / blood; Autoantibodies / immunology; Enzyme-Linked Immunosorbent Assay / methods; Female; Magnetic Resonance Spectroscopy; Malondialdehyde / immunology; Mice; Mice, Inbred C57BL; Sensitivity and Specificity
Sources: Crossref, ORCID
Added: September 5, 2021

2017 journal article

DNA Product Formation in Female Sprague–Dawley Rats Following Polyhalogenated Aromatic Hydrocarbon (PHAH) Exposure

Chemical Research in Toxicology, 30(3), 794–803.

By: L. Gao, E. Mutlu*, L. Collins*, N. Walker*, H. Hartwell, J. Olson*, W. Sun, A. Gold, L. Ball, J. Swenberg

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; DNA / drug effects; Female; Polycyclic Aromatic Hydrocarbons / toxicity; Rats; Rats, Sprague-Dawley
Sources: Crossref, ORCID
Added: September 5, 2021

2017 journal article

Evidence that endogenous formaldehyde produces immunogenic and atherogenic adduct epitopes

Scientific Reports, 7(1).

By: J. Nakamura*, T. Shimomoto*, L. Collins*, D. Holley*, Z. Zhang*, J. Barbee*, V. Sharma*, X. Tian* ...

co-author countries: Japan 🇯🇵 United States of America 🇺🇸
MeSH headings : Animals; Apolipoproteins E / deficiency; Atherosclerosis / immunology; Atherosclerosis / metabolism; Chromatography, Liquid; Epitopes / immunology; Formaldehyde / chemistry; Formaldehyde / metabolism; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Mice, Knockout; Molecular Structure; Peroxidase / metabolism; Plaque, Atherosclerotic / immunology; Plaque, Atherosclerotic / metabolism
Sources: Crossref, ORCID
Added: September 5, 2021

2017 journal article

Nontarget Analysis Reveals a Bacterial Metabolite of Pyrene Implicated in the Genotoxicity of Contaminated Soil after Bioremediation

Environmental Science & Technology, 51(12), 7091–7100.

By: Z. Tian*, A. Gold*, J. Nakamura*, Z. Zhang*, J. Vila*, D. Singleton*, L. Collins*, M. Aitken*

co-author countries: United States of America 🇺🇸
MeSH headings : Biodegradation, Environmental; Polycyclic Aromatic Hydrocarbons; Pyrenes; Soil; Soil Microbiology; Soil Pollutants
Sources: Crossref, ORCID
Added: September 5, 2021

2017 journal article

Time-matched analysis of DNA adduct formation and early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats

Archives of Toxicology, 91(10), 3427–3438.

By: V. Klaus*, H. Bastek*, K. Damme*, L. Collins*, R. Frötschl*, N. Benda*, D. Lutter*, H. Ellinger-Ziegelbauer* ...

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: Methylazoxymethanol acetate; DNA adducts; Kidney cancer; Eker rat; Biomarkers of effect; Biomarkers of exposure
MeSH headings : Animals; Cell Proliferation / drug effects; Cell Transformation, Neoplastic / drug effects; Cell Transformation, Neoplastic / pathology; DNA Adducts / analysis; DNA Damage / drug effects; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Guanine / analogs & derivatives; Guanine / metabolism; Kidney / drug effects; Kidney / metabolism; Kidney / pathology; Male; Methylazoxymethanol Acetate / administration & dosage; Methylazoxymethanol Acetate / toxicity; Rats, Mutant Strains; Time Factors
Sources: Crossref, ORCID
Added: September 5, 2021

2016 journal article

Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations

Oncotarget, 7(18), 25377–25390.

By: V. Sharma*, L. Collins*, T. Chen*, N. Herr*, S. Takeda*, W. Sun*, J. Swenberg*, J. Nakamura*

co-author countries: Japan 🇯🇵 United States of America 🇺🇸
author keywords: oxidative stress; NHEJ; mutations; clustered DNA lesions; double strand breaks
MeSH headings : Animals; Cell Line; Chickens; DNA Damage / physiology; DNA End-Joining Repair / physiology; Hydrogen Peroxide / toxicity; Mutagenesis / physiology; Oxidants / toxicity; Oxidative Stress / physiology
Sources: Crossref, ORCID
Added: September 5, 2021

2016 journal article

Polychlorinated Biphenyls Induce Oxidative DNA Adducts in Female Sprague–Dawley Rats

Chemical Research in Toxicology, 29(8), 1335–1344.

By: E. Mutlu*, L. Gao*, L. Collins*, N. Walker*, H. Hartwell*, J. Olson*, W. Sun*, A. Gold*, L. Ball*, J. Swenberg*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Chromatography, Liquid; DNA Adducts / metabolism; Female; Oxidative Stress / drug effects; Polychlorinated Biphenyls / toxicity; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry
Sources: Crossref, ORCID
Added: September 5, 2021

2015 journal article

Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung

Cancer Research, 75(15), 3108–3117.

By: S. Leng*, G. Wu*, L. Collins*, C. Thomas*, C. Tellez*, A. Jauregui*, M. Picchi*, X. Zhang* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Base Sequence; Chromosomes, Human, Pair 15 / genetics; DNA Methylation; DNA Modification Methylases / genetics; DNA Modification Methylases / metabolism; DNA Repair Enzymes / genetics; DNA Repair Enzymes / metabolism; Epithelial Cells / drug effects; Female; Gene Expression Regulation; Genetic Predisposition to Disease; Genome-Wide Association Study; Guanine / analogs & derivatives; Guanine / metabolism; Humans; Longitudinal Studies; Lung Neoplasms / genetics; Male; Methylation; Methylnitrosourea / pharmacology; Molecular Sequence Data; Polymorphism, Single Nucleotide; Smoking / genetics; Tumor Suppressor Proteins / genetics; Tumor Suppressor Proteins / metabolism; Ubiquitin-Protein Ligases / genetics
Sources: Crossref, ORCID
Added: September 5, 2021

2014 journal article

A Gnotobiotic Mouse Model Demonstrates That Dietary Fiber Protects against Colorectal Tumorigenesis in a Microbiota- and Butyrate-Dependent Manner

Cancer Discovery, 4(12), 1387–1397.

By: D. Donohoe*, D. Holley*, L. Collins*, S. Montgomery n, A. Whitmore*, A. Hillhouse*, K. Curry*, S. Renner* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Butyrates / metabolism; Carcinogens / administration & dosage; Cell Transformation, Neoplastic; Colorectal Neoplasms / etiology; Colorectal Neoplasms / pathology; Dietary Fiber; Disease Models, Animal; Germ-Free Life; Humans; Intestinal Mucosa / pathology; Mice; Microbiota; Neoplasm Grading
Sources: Crossref, ORCID
Added: September 5, 2021

2014 journal article

Comparative Analysis of the Relationship Between Trichloroethylene Metabolism and Tissue-Specific Toxicity Among Inbred Mouse Strains: Kidney Effects

Journal of Toxicology and Environmental Health, Part A, 78(1), 32–49.

By: H. Yoo*, B. Bradford*, O. Kosyk*, T. Uehara*, S. Shymonyak*, L. Collins*, W. Bodnar*, L. Ball*, A. Gold*, I. Rusyn*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Carcinogens / pharmacokinetics; Carcinogens / toxicity; Cell Proliferation / drug effects; Cysteine / analogs & derivatives; Cysteine / metabolism; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; Dichloroacetic Acid / metabolism; Ethylene Chlorohydrin / analogs & derivatives; Ethylene Chlorohydrin / metabolism; Glutathione / analogs & derivatives; Glutathione / metabolism; Hepatitis A Virus Cellular Receptor 1; Kidney / cytology; Kidney / drug effects; Kidney / metabolism; Male; Membrane Proteins / genetics; Membrane Proteins / metabolism; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Oxidation-Reduction / drug effects; PPAR alpha / genetics; PPAR alpha / metabolism; Trichloroacetic Acid / metabolism; Trichloroethylene / pharmacokinetics; Trichloroethylene / toxicity
Sources: Crossref, ORCID
Added: September 5, 2021

2014 journal article

Comparative Analysis of the Relationship Between Trichloroethylene Metabolism and Tissue-Specific Toxicity Among Inbred Mouse Strains: Liver Effects

Journal of Toxicology and Environmental Health, Part A, 78(1), 15–31.

By: H. Yoo*, B. Bradford*, O. Kosyk*, S. Shymonyak*, T. Uehara*, L. Collins*, W. Bodnar*, L. Ball*, A. Gold*, I. Rusyn*

co-author countries: United States of America 🇺🇸
MeSH headings : Administration, Oral; Animals; Carcinogens / pharmacokinetics; Carcinogens / toxicity; Cell Proliferation; Cysteine / analogs & derivatives; Cysteine / blood; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; Dichloroacetic Acid / blood; Dose-Response Relationship, Drug; Ethylene Chlorohydrin / analogs & derivatives; Ethylene Chlorohydrin / metabolism; Gene Expression; Glutathione / analogs & derivatives; Glutathione / blood; Hepatocytes / drug effects; Hepatocytes / metabolism; Liver / cytology; Liver / drug effects; Liver / metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Oxidation-Reduction / drug effects; Oxidative Stress / drug effects; Real-Time Polymerase Chain Reaction; Solvents / pharmacokinetics; Solvents / toxicity; Trichloroacetic Acid / blood; Trichloroethylene / pharmacokinetics; Trichloroethylene / toxicity
Sources: Crossref, ORCID
Added: September 5, 2021

2014 journal article

Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication

Scientific Reports, 4(1).

By: T. Shibutani*, S. Ito*, M. Toda*, R. Kanao*, L. Collins*, M. Shibata*, M. Urabe*, H. Koseki* ...

co-author countries: Japan 🇯🇵 United States of America 🇺🇸
MeSH headings : 5-Methylcytosine / metabolism; Base Pairing / genetics; Cell Proliferation / genetics; Cytosine / analogs & derivatives; Cytosine / metabolism; DNA / genetics; DNA Mismatch Repair / genetics; DNA Replication / genetics; Epigenesis, Genetic / genetics; Guanine / metabolism; Humans; Thymine DNA Glycosylase / metabolism
Sources: Crossref, ORCID
Added: September 5, 2021

2014 journal article

Molecular Dosimetry of Endogenous and Exogenous O6-Methyl-dG and N7-Methyl-G Adducts Following Low Dose [D3]-Methylnitrosourea Exposures in Cultured Human Cells

Chemical Research in Toxicology, 27(4), 480–482.

By: V. Sharma*, L. Collins*, J. Clement*, Z. Zhang*, J. Nakamura* & J. Swenberg*

co-author countries: United States of America 🇺🇸
MeSH headings : Cells, Cultured; Deoxyguanosine / analogs & derivatives; Deoxyguanosine / metabolism; Dose-Response Relationship, Drug; Guanine / analogs & derivatives; Guanine / metabolism; Humans; Methylnitrosourea / administration & dosage; Methylnitrosourea / pharmacology
Sources: Crossref, ORCID
Added: September 5, 2021

2014 journal article

The endogenous exposome

DNA Repair, 19, 3–13.

By: J. Nakamura*, E. Mutlu*, V. Sharma*, L. Collins*, W. Bodnar*, R. Yu*, Y. Lai*, B. Moeller*, K. Lu*, J. Swenberg*

co-author countries: United States of America 🇺🇸
author keywords: Endogenous exposome; DNA damage; Stable isotopes; Mutagenesis; Risk assessment
MeSH headings : Animals; Antioxidant Response Elements / genetics; DNA Adducts / drug effects; DNA Adducts / genetics; DNA Damage / drug effects; DNA Damage / genetics; Dose-Response Relationship, Drug; Isotope Labeling; Mutagenesis / drug effects; Mutagenesis / genetics
Sources: Crossref, ORCID
Added: September 5, 2021

2012 journal article

A New LC-MS/MS Method for the Quantification of Endogenous and Vinyl Chloride-Induced 7-(2-Oxoethyl)Guanine in Sprague–Dawley Rats

Chemical Research in Toxicology, 25(2), 391–399.

By: E. Mutlu, Y. Jeong, L. Collins*, A. Ham*, P. Upton, G. Hatch*, D. Winsett*, P. Evansky*, J. Swenberg

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Brain / metabolism; Chromatography, Liquid; DNA Adducts / analysis; DNA Adducts / metabolism; Guanine / analogs & derivatives; Guanine / analysis; Guanine / metabolism; Kidney / metabolism; Liver / metabolism; Lung / metabolism; Male; Rats; Rats, Sprague-Dawley; Spleen / metabolism; Tandem Mass Spectrometry; Testis / metabolism; Vinyl Chloride / pharmacokinetics
Sources: Crossref, ORCID
Added: September 5, 2021

2012 journal article

The Warburg Effect Dictates the Mechanism of Butyrate-Mediated Histone Acetylation and Cell Proliferation

Molecular Cell, 48(4), 612–626.

By: D. Donohoe*, L. Collins*, A. Wali*, R. Bigler*, W. Sun* & S. Bultman*

co-author countries: United States of America 🇺🇸
MeSH headings : Acetylation; Butyrates / metabolism; Cell Proliferation; HCT116 Cells; HT29 Cells; Histones / metabolism; Humans; Models, Biological; Tumor Cells, Cultured
Sources: Crossref, ORCID
Added: September 5, 2021

2011 journal article

Debio 0507 primarily forms diaminocyclohexane-Pt-d(GpG) and -d(ApG) DNA adducts in HCT116 cells

Cancer Chemotherapy and Pharmacology, 69(3), 665–677.

By: C. King*, S. Ramachandran*, S. Chaney*, L. Collins*, J. Swenberg*, K. deKrafft*, W. Lin*, L. Cicurel*, M. Barbier*

co-author countries: Switzerland 🇨🇭 United States of America 🇺🇸
author keywords: Debio 0507; Oxaliplatin; DNA adducts; LC/MS; UPLC/MS/MS
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / metabolism; Antineoplastic Agents / pharmacology; Cell Culture Techniques; Chromatography, High Pressure Liquid; DNA Adducts / chemistry; DNA Adducts / metabolism; Deoxyadenine Nucleotides / chemistry; Deoxyadenine Nucleotides / metabolism; Deoxyguanosine / chemistry; Deoxyguanosine / metabolism; Dinucleoside Phosphates / chemistry; Dinucleoside Phosphates / metabolism; HCT116 Cells; Humans; Organoplatinum Compounds / chemistry; Organoplatinum Compounds / metabolism; Organoplatinum Compounds / pharmacology; Oxaliplatin; Tandem Mass Spectrometry
Sources: Crossref, ORCID
Added: September 5, 2021

2011 conference paper

Pseudo-SRM Conditions Improve Detection of N 2,3-ethenoguanine in DNA

Mutlu, E., Collins, L., Stout, M., Upton, P., Daye, L., Winsett, D., … Swenberg, J. (2011, June). Poster presented at the 59th American Society for Mass Spectrometry Conference, Denver, CO.

By: E. Mutlu, L. Collins, M. Stout, P. Upton, L. Daye, D. Winsett, G. Hatch, P. Evansky, J. Swenberg

Event: 59th American Society for Mass Spectrometry Conference at Denver, CO on June 5-9, 2011

Source: NC State University Libraries
Added: September 9, 2021

2011 journal article

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

Science, 333(6047), 1300–1303.

By: S. Ito*, L. Shen*, Q. Dai*, S. Wu*, L. Collins*, J. Swenberg*, C. He*, Y. Zhang*

co-author countries: United States of America 🇺🇸
MeSH headings : 5-Methylcytosine / metabolism; Animals; Cell Line; Cytosine / analogs & derivatives; Cytosine / metabolism; DNA / metabolism; DNA Methylation; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Dioxygenases; Embryonic Stem Cells / metabolism; Humans; Mice; Oxidation-Reduction; Proto-Oncogene Proteins / genetics; Proto-Oncogene Proteins / metabolism; Recombinant Fusion Proteins / metabolism
Sources: Crossref, ORCID
Added: September 5, 2021

2010 journal article

Analysis of 8-oxo-7,8-dihydro-2′-deoxyguanosine by ultra high pressure liquid chromatography–heat assisted electrospray ionization–tandem mass spectrometry

Journal of Chromatography B, 878(3-4), 375–380.

By: G. Boysen*, L. Collins*, S. Liao*, A. Luke*, B. Pachkowski*, J. Watters*, J. Swenberg*

co-author countries: United States of America 🇺🇸
author keywords: 8-Oxo-7,8-dihydro-2 '-deoxyguanosine; Oxidative stress; LC-MS
MeSH headings : 8-Hydroxy-2'-Deoxyguanosine; Adult; Animals; Chromatography, High Pressure Liquid / methods; DNA / metabolism; Deoxyguanosine / analogs & derivatives; Deoxyguanosine / analysis; Freezing; HeLa Cells; Hot Temperature; Humans; Hydrogen Peroxide / pharmacology; Lymphocytes / drug effects; Lymphocytes / metabolism; Middle Aged; Rats; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization / methods; Tandem Mass Spectrometry / methods; Young Adult
Sources: Crossref, ORCID
Added: September 5, 2021

2010 journal article

Development and Application of an LC-MS/MS Method for the Detection of the Vinyl Chloride-Induced DNA Adduct N2,3-Ethenoguanine in Tissues of Adult and Weanling Rats Following Exposure to [13C2]-VC

Chemical Research in Toxicology, 23(9), 1485–1491.

By: E. Mutlu*, L. Collins*, M. Stout*, P. Upton*, L. Daye*, D. Winsett*, G. Hatch*, P. Evansky*, J. Swenberg*

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: September 5, 2021

2010 journal article

Distribution of DNA Adducts Caused by Inhaled Formaldehyde Is Consistent with Induction of Nasal Carcinoma but Not Leukemia

Toxicological Sciences, 116(2), 441–451.

By: K. Lu, L. Collins*, H. Ru*, E. Bermudez* & J. Swenberg

co-author countries: United States of America 🇺🇸
author keywords: formaldehyde; DNA adduct; DNA-DNA cross-link; cancer; leukemia
MeSH headings : Animals; Chromatography, High Pressure Liquid; DNA Adducts / analysis; Formaldehyde / metabolism; Formaldehyde / toxicity; Inhalation Exposure; Leukemia / chemically induced; Male; Nose Neoplasms / chemically induced; Rats; Rats, Inbred F344; Spectrometry, Mass, Electrospray Ionization
Sources: Crossref, ORCID
Added: September 5, 2021

2010 journal article

Structural Characterization of Formaldehyde-Induced Cross-Links Between Amino Acids and Deoxynucleosides and Their Oligomers

Journal of the American Chemical Society, 132(10), 3388–3399.

By: K. Lu*, W. Ye*, L. Zhou*, L. Collins*, X. Chen*, A. Gold*, L. Ball*, J. Swenberg*

co-author countries: United States of America 🇺🇸
MeSH headings : Amino Acids / chemistry; Chromatography, High Pressure Liquid; Cross-Linking Reagents / chemistry; Deoxyadenosines / chemistry; Deoxycytidine / chemistry; Deoxyguanosine / chemistry; Formaldehyde / chemistry; Formic Acid Esters / chemistry; Nuclear Magnetic Resonance, Biomolecular / methods; Nucleosides / chemistry; Oligonucleotides / chemistry; Oligopeptides / chemistry; Spectroscopy, Fourier Transform Infrared; Tandem Mass Spectrometry / methods; Thymidine / chemistry
Sources: Crossref, ORCID
Added: September 5, 2021

2009 journal article

Accurate quantitation of standard peptides used for quantitative proteomics

Proteomics, 9(15), 3939–3944.

By: N. Bordeerat*, N. Georgieva*, D. Klapper*, L. Collins*, T. Cross*, C. Borchers*, J. Swenberg*, G. Boysen*

co-author countries: Canada 🇨🇦 United States of America 🇺🇸
author keywords: Peptide standards; Quality control; Quantitative analysis
MeSH headings : Chromatography, Liquid / economics; Chromatography, Liquid / methods; Peptides / analysis; Proteomics / economics; Proteomics / methods; Sensitivity and Specificity; Tandem Mass Spectrometry / economics; Tandem Mass Spectrometry / methods
Sources: Crossref, ORCID
Added: September 5, 2021

2009 journal article

Comparison of three oxidative stress biomarkers in a sample of healthy adults

Biomarkers, 14(8), 587–595.

By: J. Watters*, J. Satia, K. Costa, G. Boysen, L. Collins*, J. Morrow*, G. Milne*, J. Swenberg

co-author countries: United States of America 🇺🇸
author keywords: Oxidation DNA damage; lipid peroxidation; 8-hydroxy-2-deoxyguanosine; comet assay; isoprostanes
MeSH headings : 8-Hydroxy-2'-Deoxyguanosine; Adult; Biomarkers / analysis; Biomarkers / metabolism; Comet Assay; DNA Damage; DNA-Formamidopyrimidine Glycosylase; Deoxyguanosine / analogs & derivatives; Deoxyguanosine / metabolism; F2-Isoprostanes / metabolism; Female; Humans; Lipid Peroxidation; Male; Middle Aged; Oxidative Stress
Sources: Crossref, ORCID
Added: September 5, 2021

2009 journal article

Development of an Ultraperformance Liquid Chromatography/Mass Spectrometry Method To Quantify Cisplatin 1,2 Intrastrand Guanine−Guanine Adducts

Chemical Research in Toxicology, 22(5), 905–912.

By: I. Baskerville-Abraham, G. Boysen*, J. Troutman*, E. Mutlu*, L. Collins*, K. deKrafft*, W. Lin*, C. King*, S. Chaney*, J. Swenberg*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Carboplatin / chemistry; Cattle; Cell Line, Tumor; Chromatography, High Pressure Liquid / methods; Cisplatin / chemistry; DNA / chemistry; Female; Guanine / chemistry; Mice; Mice, Inbred C57BL; Ribonucleosides / chemistry; Tandem Mass Spectrometry / methods
Sources: Crossref, ORCID
Added: September 5, 2021

2009 journal article

Liquid chromatography electrospray ionization tandem mass spectrometry analysis method for simultaneous detection of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine

Toxicology, 262(3), 230–238.

By: S. Kim*, L. Collins*, G. Boysen*, J. Swenberg*, A. Gold*, L. Ball*, B. Bradford*, I. Rusyn*

co-author countries: United States of America 🇺🇸
author keywords: Trichloroethylene metabolites; HPLC-ESI-MS/MS; Dichloroacetic acid; Trichloroacetic acid; S-(1,2-dichlorovinyl)-L-cysteine; S-(1,2-dichlorovinyl)glutathione; HILIC
MeSH headings : Animals; Chromatography, High Pressure Liquid / methods; Cysteine / analogs & derivatives; Cysteine / blood; Dichloroacetic Acid / blood; Glutathione / analogs & derivatives; Glutathione / blood; Male; Mice; Spectrometry, Mass, Electrospray Ionization / methods; Tandem Mass Spectrometry / methods; Trichloroacetic Acid / blood; Trichloroethylene / metabolism
Sources: Crossref, ORCID
Added: September 5, 2021

2009 journal article

Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: Formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-l-cysteine

Toxicology and Applied Pharmacology, 238(1), 90–99.

By: S. Kim*, D. Kim*, G. Pollack*, L. Collins* & I. Rusyn*

co-author countries: United States of America 🇺🇸
author keywords: Trichloroethylene; Metabolism; Pharmacokinetics; Trichloroacetic acid; Dichloroacetic acid; S-(1,2-dichlorovinyl)glutathione; S-(1,2-dichlorovinyl)-L-cysteine
MeSH headings : Administration, Oral; Animals; Biological Availability; Carcinogens / pharmacokinetics; Cysteine / analogs & derivatives; Cysteine / pharmacokinetics; Dichloroacetic Acid / pharmacokinetics; Glutathione / analogs & derivatives; Glutathione / metabolism; Glutathione / pharmacokinetics; Half-Life; Male; Mice; Models, Biological; Oxidation-Reduction; Risk Assessment; Time Factors; Trichloroacetic Acid / pharmacokinetics; Trichloroethylene / pharmacokinetics
Sources: Crossref, ORCID
Added: September 5, 2021

2008 journal article

A mass spectrometric method to simultaneously measure a biomarker and dilution marker in exhaled breath condensate

Rapid Communications in Mass Spectrometry, 22(5), 701–705.

By: C. Esther*, H. Jasin*, L. Collins*, J. Swenberg* & G. Boysen*

co-author countries: United States of America 🇺🇸
MeSH headings : Adenosine / analysis; Adenosine / metabolism; Adenosine Monophosphate / analysis; Adenosine Monophosphate / metabolism; Biomarkers / analysis; Biomarkers / metabolism; Breath Tests / methods; Bronchi / metabolism; Child; Chromatography, High Pressure Liquid; Cystic Fibrosis / metabolism; Exhalation; Humans; Prospective Studies; Spectrometry, Mass, Electrospray Ionization / methods; Tandem Mass Spectrometry / methods; Urea / analysis; Urea / metabolism
Sources: Crossref, ORCID
Added: September 5, 2021

2008 journal article

Formaldehyde-Induced Histone Modifications in Vitro

Chemical Research in Toxicology, 21(8), 1586–1593.

By: K. Lu*, G. Boysen*, L. Gao*, L. Collins* & J. Swenberg*

co-author countries: United States of America 🇺🇸
MeSH headings : Binding Sites; Chromatography, High Pressure Liquid; Cross-Linking Reagents / chemistry; Cross-Linking Reagents / metabolism; DNA / drug effects; DNA Damage; Formaldehyde / chemistry; Formaldehyde / metabolism; Histones / chemistry; Histones / metabolism; In Vitro Techniques; Lysine / chemistry; Lysine / metabolism; Peptide Fragments / chemistry; Peptide Mapping; Protein Binding; Protein Structure, Tertiary; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tandem Mass Spectrometry
Sources: Crossref, ORCID
Added: September 5, 2021

2005 conference paper

Use of QuEChERS for residue determination in unusual matrices

Collins, L. B. (2005, April 27). Presented at the 19th annual meeting of the Southeast Regional Section of the AOAC International, Atlanta, GA.

By: L. Collins

Event: 19th annual meeting of the Southeast Regional Section of the AOAC International at Atlanta, GA on April 27, 2005

Source: NC State University Libraries
Added: September 9, 2021

1998 conference paper

HPLC/UV method for determination of Tepraloxydim major metabolites in soil and sediment

Saha, M., Harrison, B., & Collins, L. B. (1998, August 23). Poster presented at the 216th American Chemical Society (ACS) National Meeting, Boston, MA.

By: M. Saha, B. Harrison & L. Collins

Event: 216th American Chemical Society (ACS) National Meeting at Boston, MA on August 23-27, 1998

Source: NC State University Libraries
Added: September 9, 2021

1994 journal article

Interference by pH and Ca2+ ions during measurements of catecholamine release in slices of rat amygdala with fast-scan cyclic voltammetry

Journal of Neuroscience Methods, 52(1), 1–10.

By: S. Jones*, G. Mickelson*, L. Collins*, K. Kawagoe* & R. Mark Wightman*

co-author countries: United States of America 🇺🇸
author keywords: STRIATUM; BASOLATERAL AMYGDALA; DOPAMINE RELEASE; FAST-SCAN CYCLIC VOLTAMMETRY; L-DOPA; ION-SELECTIVE MICROELECTRODE; CALCIUM; PH
MeSH headings : Amygdala / metabolism; Animals; Calcium / physiology; Carbon; Catecholamines / deficiency; Catecholamines / metabolism; Caudate Nucleus / metabolism; Dopamine / pharmacology; Electrophysiology / instrumentation; Electrophysiology / methods; Hydrogen-Ion Concentration; In Vitro Techniques; Levodopa / pharmacology; Male; Microelectrodes; Rats; Rats, Sprague-Dawley; Time Factors
Sources: Crossref, ORCID
Added: September 5, 2021

1993 journal article

Evoked Extracellular Dopamine In Vivo in the Medial Prefrontal Cortex

Journal of Neurochemistry, 61(2), 637–647.

By: P. Garris*, L. Collins*, S. Jones* & R. Wightman*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Dopamine / metabolism; Electric Stimulation; Electrochemistry; Extracellular Space / metabolism; Kinetics; Male; Methyltyrosines / pharmacology; Microelectrodes; Neurons / metabolism; Norepinephrine / metabolism; Prefrontal Cortex / drug effects; Prefrontal Cortex / metabolism; Rats; Rats, Sprague-Dawley; alpha-Methyltyrosine
Sources: Crossref, ORCID
Added: September 5, 2021

Employment

Updated: April 14th, 2020 17:29

2020 - present

North Carolina State University Raleigh, North Carolina, US
Research Assistant METRIC

2006 - 2020

University of North Carolina at Chapel Hill Chapel Hill, NC, US
Research Specialist Environmental Sciences and Engineering

1999 - 2005

Mississippi State Chemical Laboratory Starkville, Mississippi, US
Research Associate

1994 - 1999

BASF Corporation Research Triangle Park, North Carolina, US
Associate Chemist Agricultural Products Unit

1993 - 1994

Magellan Laboratories, Inc. Morrisville, North Carolina, US
Analyst

Education

Updated: August 29th, 2021 11:53

2000 - 2004

Mississippi State University Starkville, MS, US
MBA

1989 - 1993

University of North Carolina at Chapel Hill Chapel Hill, North Carolina, US
BS

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