Leonard Collins
Adams, V. R., Collins, L. B., Williams, T. I., Holmes, J., Hess, P., Atkins, H. M., … Kennedy, A. (2024). Myeloid cell MHC I expression drives CD8+ T cell activation in nonalcoholic steatohepatitis. FRONTIERS IN IMMUNOLOGY, 14. https://doi.org/10.3389/fimmu.2023.1302006
Bai, H., Collins, L. B. B., Andre, M. R., Breitschwerdt, E. B. B., & Williams, T. I. (2023, January 3). A bottom-up proteomics workflow for a system containing multiple organisms. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, Vol. 1. https://doi.org/10.1002/rcm.9431
Williams, T. I., Kowalchyk, C., Collins, L. B., & Reading, B. J. (2023, March 22). Discovery Proteomics and Absolute Protein Quantification Can Be Performed Simultaneously on an Orbitrap-Based Mass Spectrometer. ACS OMEGA, Vol. 3. https://doi.org/10.1021/acsomega.2c07614
McGuigan, S., Tereniak, S. J., Donley, C. L., Smith, A., Jeon, S., Zhao, F., … Maggard, P. A. (2023, October 12). Discovery of a Hybrid System for Photocatalytic CO2 Reduction via Attachment of a Molecular Cobalt-Quaterpyridine Complex to a Crystalline Carbon Nitride. ACS APPLIED ENERGY MATERIALS, Vol. 10. https://doi.org/10.1021/acsaem.3c01670
Durmusoglu, D., Al'Abri, I., Li, Z., Islam Williams, T., Collins, L. B., Martinez, J. L., & Crook, N. (2023). Improving therapeutic protein secretion in the probiotic yeast Saccharomyces boulardii using a multifactorial engineering approach. MICROBIAL CELL FACTORIES, 22(1). https://doi.org/10.1186/s12934-023-02117-y
Sripada, S. A., Elhanafi, D., Collins, L. B., Williams, T. I., Linova, M. Y., Woodley, J. M., … Menegatti, S. (2023). Pseudo-affinity capture of K. phaffii host cell proteins in flow-through mode: Purification of protein therapeutics and proteomic study. SEPARATION AND PURIFICATION TECHNOLOGY, 326. https://doi.org/10.1016/j.seppur.2023.124777
Orr, S. E., Collins, L. B., Jima, D. D., & Buchwalter, D. B. (2023). Salinity-induced ionoregulatory changes in the gill proteome of the mayfly, Neocloeon triangulifer. ENVIRONMENTAL POLLUTION, 316. https://doi.org/10.1016/j.envpol.2022.120609
Durmusoglu, D., Al’Abri, I., Williams, T. I., Collins, L. B., Martínez, J. L., & Crook, N. (2022, December 31). Improving Therapeutic Protein Secretion in the Probiotic YeastSaccharomyces boulardiiusing a Multifactorial Engineering Approach. BioRxiv. https://doi.org/10.1101/2022.12.30.522352
Manley, O. M., Phan, H. N., Stewart, A. K., Mosley, D. A., Xue, S., Cha, L., … Makris, T. M. (2022). Self-sacrificial tyrosine cleavage by an Fe:Mn oxygenase for the biosynthesis of para-aminobenzoate in Chlamydia trachomatis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(39). https://doi.org/10.1073/pnas.2210908119
Biehl, A., Martins, A. M. G. M., Davis, Z. G. G., Sze, D., Collins, L., Mora-Navarro, C., … Freytes, D. O. O. (2022, December 12). Towards a standardized multi-tissue decellularization protocol for the derivation of extracellular matrix materials. BIOMATERIALS SCIENCE, Vol. 12. https://doi.org/10.1039/d2bm01012g
Andre, M. R., Neupane, P., Lappin, M., Herrin, B., Smith, V., Williams, T. I., … Breitschwerdt, E. B. (2022). Using Proteomic Approaches to Unravel the Response of Ctenocephalides felis felis to Blood Feeding and Infection With Bartonella henselae. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 12. https://doi.org/10.3389/fcimb.2022.828082
Zhou, J., Baumann, K., Mead, R. N., Skrabal, S. A., Kieber, R. J., Avery, G. B., … Turpin, B. J. (2021). PFOS dominates PFAS composition in ambient fine particulate matter (PM2.5) collected across North Carolina nearly 20 years after the end of its US production. ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS, 23(4), 580–587. https://doi.org/10.1039/d0em00497a
Isom, D. G., Page, S. C., Collins, L. B., Kapolka, N. J., Taghon, G. J., & Dohlman, H. G. (2018). Coordinated regulation of intracellular pH by two glucose-sensing pathways in yeast. Journal of Biological Chemistry, 293(7), 2318–2329. https://doi.org/10.1074/jbc.ra117.000422
Cui, T., Zeng, Z., dos Santos, E. O., Zhang, Z., Chen, Y., Zhang, Y., … Surratt, J. D. (2018). Development of a hydrophilic interaction liquid chromatography (HILIC) method for the chemical characterization of water-soluble isoprene epoxydiol (IEPOX)-derived secondary organic aerosol. Environmental Science: Processes & Impacts, 20(11), 1524–1536. https://doi.org/10.1039/c8em00308d
Shimomoto, T., Collins, L. B., Yi, X., Holley, D. W., Zhang, Z., Tian, X., … Nakamura, J. (2017). A purified MAA-based ELISA is a useful tool for determining anti-MAA antibody titer with high sensitivity. PLOS ONE, 12(2), e0172172. https://doi.org/10.1371/journal.pone.0172172
Gao, L., Mutlu, E., Collins, L. B., Walker, N. J., Hartwell, H. J., Olson, J. R., … Swenberg, J. A. (2017). DNA Product Formation in Female Sprague–Dawley Rats Following Polyhalogenated Aromatic Hydrocarbon (PHAH) Exposure. Chemical Research in Toxicology, 30(3), 794–803. https://doi.org/10.1021/acs.chemrestox.6b00368
Nakamura, J., Shimomoto, T., Collins, L. B., Holley, D. W., Zhang, Z., Barbee, J. M., … Bultman, S. J. (2017). Evidence that endogenous formaldehyde produces immunogenic and atherogenic adduct epitopes. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-11289-8
Tian, Z., Gold, A., Nakamura, J., Zhang, Z., Vila, J., Singleton, D. R., … Aitken, M. D. (2017). Nontarget Analysis Reveals a Bacterial Metabolite of Pyrene Implicated in the Genotoxicity of Contaminated Soil after Bioremediation. Environmental Science & Technology, 51(12), 7091–7100. https://doi.org/10.1021/acs.est.7b01172
Klaus, V., Bastek, H., Damme, K., Collins, L. B., Frötschl, R., Benda, N., … Stemmer, K. (2017). Time-matched analysis of DNA adduct formation and early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats. Archives of Toxicology, 91(10), 3427–3438. https://doi.org/10.1007/s00204-017-1953-6
Sharma, V., Collins, L. B., Chen, T.-huei, Herr, N., Takeda, S., Sun, W., … Nakamura, J. (2016). Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations. Oncotarget, 7(18), 25377–25390. https://doi.org/10.18632/oncotarget.8298
Mutlu, E., Gao, L., Collins, L. B., Walker, N. J., Hartwell, H. J., Olson, J. R., … Swenberg, J. A. (2016). Polychlorinated Biphenyls Induce Oxidative DNA Adducts in Female Sprague–Dawley Rats. Chemical Research in Toxicology, 29(8), 1335–1344. https://doi.org/10.1021/acs.chemrestox.6b00146
Leng, S., Wu, G., Collins, L. B., Thomas, C. L., Tellez, C. S., Jauregui, A. R., … Belinsky, S. A. (2015). Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung. Cancer Research, 75(15), 3108–3117. https://doi.org/10.1158/0008-5472.can-15-0243
Donohoe, D. R., Holley, D., Collins, L. B., Montgomery, S. A., Whitmore, A. C., Hillhouse, A., … Bultman, S. J. (2014). A Gnotobiotic Mouse Model Demonstrates That Dietary Fiber Protects against Colorectal Tumorigenesis in a Microbiota- and Butyrate-Dependent Manner. Cancer Discovery, 4(12), 1387–1397. https://doi.org/10.1158/2159-8290.cd-14-0501
Yoo, H. S., Bradford, B. U., Kosyk, O., Uehara, T., Shymonyak, S., Collins, L. B., … Rusyn, I. (2014). Comparative Analysis of the Relationship Between Trichloroethylene Metabolism and Tissue-Specific Toxicity Among Inbred Mouse Strains: Kidney Effects. Journal of Toxicology and Environmental Health, Part A, 78(1), 32–49. https://doi.org/10.1080/15287394.2015.958418
Yoo, H. S., Bradford, B. U., Kosyk, O., Shymonyak, S., Uehara, T., Collins, L. B., … Rusyn, I. (2014). Comparative Analysis of the Relationship Between Trichloroethylene Metabolism and Tissue-Specific Toxicity Among Inbred Mouse Strains: Liver Effects. Journal of Toxicology and Environmental Health, Part A, 78(1), 15–31. https://doi.org/10.1080/15287394.2015.958417
Shibutani, T., Ito, S., Toda, M., Kanao, R., Collins, L. B., Shibata, M., … Kuraoka, I. (2014). Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication. Scientific Reports, 4(1). https://doi.org/10.1038/srep05220
Sharma, V., Collins, L. B., Clement, J. M., Zhang, Z., Nakamura, J., & Swenberg, J. A. (2014). Molecular Dosimetry of Endogenous and Exogenous O6-Methyl-dG and N7-Methyl-G Adducts Following Low Dose [D3]-Methylnitrosourea Exposures in Cultured Human Cells. Chemical Research in Toxicology, 27(4), 480–482. https://doi.org/10.1021/tx5000602
Nakamura, J., Mutlu, E., Sharma, V., Collins, L., Bodnar, W., Yu, R., … Swenberg, J. (2014). The endogenous exposome. DNA Repair, 19, 3–13. https://doi.org/10.1016/j.dnarep.2014.03.031
Mutlu, E., Jeong, Y.-C., Collins, L. B., Ham, A.-J. L., Upton, P. B., Hatch, G., … Swenberg, J. A. (2012). A New LC-MS/MS Method for the Quantification of Endogenous and Vinyl Chloride-Induced 7-(2-Oxoethyl)Guanine in Sprague–Dawley Rats. Chemical Research in Toxicology, 25(2), 391–399. https://doi.org/10.1021/tx200447w
Donohoe, D. R., Collins, L. B., Wali, A., Bigler, R., Sun, W., & Bultman, S. J. (2012). The Warburg Effect Dictates the Mechanism of Butyrate-Mediated Histone Acetylation and Cell Proliferation. Molecular Cell, 48(4), 612–626. https://doi.org/10.1016/j.molcel.2012.08.033
King, C. L., Ramachandran, S., Chaney, S. G., Collins, L., Swenberg, J. A., deKrafft, K. E., … Barbier, M. (2011). Debio 0507 primarily forms diaminocyclohexane-Pt-d(GpG) and -d(ApG) DNA adducts in HCT116 cells. Cancer Chemotherapy and Pharmacology, 69(3), 665–677. https://doi.org/10.1007/s00280-011-1744-3
Mutlu, E., Collins, L., Stout, M., Upton, P., Daye, L., Winsett, D., … Swenberg, J. (2011, June). Pseudo-SRM Conditions Improve Detection of N 2,3-ethenoguanine in DNA. Poster presented at the 59th American Society for Mass Spectrometry Conference, Denver, CO.
Ito, S., Shen, L., Dai, Q., Wu, S. C., Collins, L. B., Swenberg, J. A., … Zhang, Y. (2011). Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine. Science, 333(6047), 1300–1303. https://doi.org/10.1126/science.1210597
Boysen, G., Collins, L. B., Liao, S., Luke, A. M., Pachkowski, B. F., Watters, J. L., & Swenberg, J. A. (2010). Analysis of 8-oxo-7,8-dihydro-2′-deoxyguanosine by ultra high pressure liquid chromatography–heat assisted electrospray ionization–tandem mass spectrometry. Journal of Chromatography B, 878(3-4), 375–380. https://doi.org/10.1016/j.jchromb.2009.12.004
Mutlu, E., Collins, L. B., Stout, M. D., Upton, P. B., Daye, L. R., Winsett, D., … Swenberg, J. A. (2010). Development and Application of an LC-MS/MS Method for the Detection of the Vinyl Chloride-Induced DNA Adduct N2,3-Ethenoguanine in Tissues of Adult and Weanling Rats Following Exposure to [13C2]-VC. Chemical Research in Toxicology, 23(9), 1485–1491. https://doi.org/10.1021/tx1001767
Lu, K., Collins, L. B., Ru, H., Bermudez, E., & Swenberg, J. A. (2010). Distribution of DNA Adducts Caused by Inhaled Formaldehyde Is Consistent with Induction of Nasal Carcinoma but Not Leukemia. Toxicological Sciences, 116(2), 441–451. https://doi.org/10.1093/toxsci/kfq061
Lu, K., Ye, W., Zhou, L., Collins, L. B., Chen, X., Gold, A., … Swenberg, J. A. (2010). Structural Characterization of Formaldehyde-Induced Cross-Links Between Amino Acids and Deoxynucleosides and Their Oligomers. Journal of the American Chemical Society, 132(10), 3388–3399. https://doi.org/10.1021/ja908282f
Bordeerat, N. K., Georgieva, N. I., Klapper, D. G., Collins, L. B., Cross, T. J., Borchers, C. H., … Boysen, G. (2009). Accurate quantitation of standard peptides used for quantitative proteomics. Proteomics, 9(15), 3939–3944. https://doi.org/10.1002/pmic.200900043
Watters, J. L., Satia, J. A., Costa, K.-A. da, Boysen, G., Collins, L. B., Morrow, J. D., … Swenberg, J. A. (2009). Comparison of three oxidative stress biomarkers in a sample of healthy adults. Biomarkers, 14(8), 587–595. https://doi.org/10.3109/13547500903183954
Baskerville-Abraham, I. M., Boysen, G., Troutman, J. M., Mutlu, E., Collins, L., deKrafft, K. E., … Swenberg, J. A. (2009). Development of an Ultraperformance Liquid Chromatography/Mass Spectrometry Method To Quantify Cisplatin 1,2 Intrastrand Guanine−Guanine Adducts. Chemical Research in Toxicology, 22(5), 905–912. https://doi.org/10.1021/tx800481j
Kim, S., Collins, L. B., Boysen, G., Swenberg, J. A., Gold, A., Ball, L. M., … Rusyn, I. (2009). Liquid chromatography electrospray ionization tandem mass spectrometry analysis method for simultaneous detection of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine. Toxicology, 262(3), 230–238. https://doi.org/10.1016/j.tox.2009.06.013
Kim, S., Kim, D., Pollack, G. M., Collins, L. B., & Rusyn, I. (2009). Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: Formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-l-cysteine. Toxicology and Applied Pharmacology, 238(1), 90–99. https://doi.org/10.1016/j.taap.2009.04.019
Esther, C. R., Jr, Jasin, H. M., Collins, L. B., Swenberg, J. A., & Boysen, G. (2008). A mass spectrometric method to simultaneously measure a biomarker and dilution marker in exhaled breath condensate. Rapid Communications in Mass Spectrometry, 22(5), 701–705. https://doi.org/10.1002/rcm.3408
Lu, K., Boysen, G., Gao, L., Collins, L. B., & Swenberg, J. A. (2008). Formaldehyde-Induced Histone Modifications in Vitro. Chemical Research in Toxicology, 21(8), 1586–1593. https://doi.org/10.1021/tx8000576
Collins, L. B. (2005, April 27). Use of QuEChERS for residue determination in unusual matrices. Presented at the 19th annual meeting of the Southeast Regional Section of the AOAC International, Atlanta, GA.
Saha, M., Harrison, B., & Collins, L. B. (1998, August 23). HPLC/UV method for determination of Tepraloxydim major metabolites in soil and sediment. Poster presented at the 216th American Chemical Society (ACS) National Meeting, Boston, MA.
Jones, S. R., Mickelson, G. E., Collins, L. B., Kawagoe, K. T., & Mark Wightman, R. (1994). Interference by pH and Ca2+ ions during measurements of catecholamine release in slices of rat amygdala with fast-scan cyclic voltammetry. Journal of Neuroscience Methods, 52(1), 1–10. https://doi.org/10.1016/0165-0270(94)90048-5
Garris, P. A., Collins, L. B., Jones, S. R., & Wightman, R. M. (1993). Evoked Extracellular Dopamine In Vivo in the Medial Prefrontal Cortex. Journal of Neurochemistry, 61(2), 637–647. https://doi.org/10.1111/j.1471-4159.1993.tb02168.x