Lide Cha

Phan, H. N., Manley, O. M., Skirboll, S. S., Cha, L., Hilovsky, D., Chang, W.-chen, … Makris, T. M. (2023). Excision of a Protein-Derived Amine for <i>p</i>-Aminobenzoate Assembly by the Self-Sacrificial Heterobimetallic Protein CADD. BIOCHEMISTRY, 62(22), 3276–3282. https://doi.org/10.1021/acs.biochem.3c00406

Ushimaru, R., Cha, L., Shimo, S., Li, X., Paris, J. C., Mori, T., … Abe, I. (2023). Mechanistic Analysis of Stereodivergent Nitroalkane Cyclopropanation Catalyzed by Nonheme Iron Enzymes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 145(44), 24210–24217. https://doi.org/10.1021/jacs.3c08413

Cha, L., Paris, J. C., Zanella, B., Spletzer, M., Yao, A., Guo, Y., & Chang, W.-chen. (2023, March 13). Mechanistic Studies of Aziridine Formation Catalyzed by Mononuclear Non-Heme Iron Enzymes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol. 3. https://doi.org/10.1021/jacs.2c12664

Wang, B., Lu, Y., Cha, L., Chen, T.-Y., Palacios, P. M., Li, L., … Chen, C. (2023, September 6). Repurposing Iron- and 2-Oxoglutarate-Dependent Oxygenases to Catalyze Olefin Hydration. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, Vol. 9. https://doi.org/10.1002/anie.202311099

Chen, T.-Y., Zheng, Z., Zhang, X., Chen, J., Cha, L., Tang, Y., … Chang, W.-chen. (2022). Deciphering the Reaction Pathway of Mononuclear Iron Enzyme-Catalyzed N C Triple Bond Formation in Isocyanide Lipopeptide and Polyketide Biosynthesis. ACS CATALYSIS, 12(4), 2270–2279. https://doi.org/10.1021/acscatal.1c04869

Kim, W., Chen, T.-Y., Cha, L., Zhou, G., Xing, K., Canty, N. K., … Chang, W.-C. (2022). Elucidation of divergent desaturation pathways in the formation of vinyl isonitrile and isocyanoacrylate. NATURE COMMUNICATIONS, 13(1). https://doi.org/10.1038/s41467-022-32870-4

Manley, O. M., Phan, H. N., Stewart, A. K., Mosley, D. A., Xue, S., Cha, L., … Makris, T. M. (2022). Self-sacrificial tyrosine cleavage by an Fe:Mn oxygenase for the biosynthesis of para-aminobenzoate in Chlamydia trachomatis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(39). https://doi.org/10.1073/pnas.2210908119

Cha, L., Milikisiyants, S., Davidson, M., Xue, S., Smirnova, T. I., Smirnov, A. I., … Chang, W.-C. (2020). Alternative Reactivity of Leucine 5-Hydroxylase Using an Olefin-Containing Substrate to Construct a Substituted Piperidine Ring. BIOCHEMISTRY, 59(21), 1961–1965. https://doi.org/10.1021/acs.biochem.0c00289

Cha, L., & Chang, W.-chen. (2020, December). An Effective Strategy to Introduce Carbon Isotopes by Simple Swaps of CO2. TRENDS IN CHEMISTRY, Vol. 2, pp. 1040–1042. https://doi.org/10.1016/j.trechm.2020.10.004

Li, J., Liao, H.-J., Tang, Y., Huang, J.-L., Cha, L., Lin, T.-S., … Guo, Y. (2020). Epoxidation Catalyzed by the Nonheme Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, AsqJ: Mechanistic Elucidation of Oxygen Atom Transfer by a Ferryl Intermediate. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 142(13), 6268–6284. https://doi.org/10.1021/jacs.0c00484

Yu, C.-P., Tang, Y., Cha, L., Milikisiyants, S., Smirnova, T. I., Smirnov, A. I., … Chang, W.-chen. (2018). Elucidating the Reaction Pathway of Decarboxylation-Assisted Olefination Catalyzed by a Mononuclear Non-Heme Iron Enzyme. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 140(45), 15190–15193. https://doi.org/10.1021/jacs.8b10077