Works (5)

Updated: July 5th, 2023 15:43

2016 journal article

Use of RNA-seq to identify cardiac genes and gene pathways differentially expressed between dogs with and without dilated cardiomyopathy


By: S. Friedenberg n, L. Chdid n, B. Keene n, B. Sherry n, A. Motsinger-Reif n & K. Meurs n

MeSH headings : Animals; Cardiomyopathy, Dilated / genetics; Cardiomyopathy, Dilated / metabolism; Cardiomyopathy, Dilated / veterinary; Dog Diseases / genetics; Dog Diseases / metabolism; Dogs; Down-Regulation; Female; Gene Expression; Heart Ventricles; Male; Myocardium / metabolism; RNA / genetics; Up-Regulation
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Evaluation of a DLA-79 allele associated with multiple immune-mediated diseases in dogs

Immunogenetics, 68(3), 205–217.

By: S. Friedenberg n, G. Buhrman n, L. Chdid n, N. Olby n, T. Olivry n, J. Guillaumin*, T. O’Toole*, R. Goggs* ...

author keywords: Canine; Immune-mediated disease; Dog leukocyte antigen; Major histocompatibility complex class Ib
MeSH headings : Alleles; Amino Acid Substitution; Animals; Autoimmune Diseases / genetics; Autoimmune Diseases / immunology; Binding Sites; Dog Diseases / genetics; Dog Diseases / immunology; Dogs; Exons; Gene Frequency; Genetic Predisposition to Disease; Genotype; Histocompatibility Antigens Class I / chemistry; Histocompatibility Antigens Class I / genetics; Histocompatibility Antigens Class I / immunology; Immune System Diseases / veterinary; Meta-Analysis as Topic; Models, Molecular; Peptides / chemistry; Peptides / metabolism; Phenotype; Polymorphism, Single Nucleotide; Protein Conformation; Reproducibility of Results; Structure-Activity Relationship
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2015 journal article

Impact of the canine double-deletion beta 1 adrenoreceptor polymorphisms on protein structure and heart rate response to atenolol, a beta 1-selective beta-blocker


By: K. Meurs n, J. Stern n, Y. Reina-Doreste n, B. Maran n, L. Chdid n, S. Lahmers n, B. Keene n, K. Mealey n

author keywords: beta-adrenergic receptor; atenolol; beta-blocker; canine; polymorphism
MeSH headings : Adrenergic beta-1 Receptor Antagonists / administration & dosage; Adrenergic beta-1 Receptor Antagonists / pharmacology; Animals; Atenolol / administration & dosage; Atenolol / pharmacology; Dogs; Electrocardiography / veterinary; Heart Rate / drug effects; Models, Molecular; Protein Structure, Secondary; Receptors, Adrenergic, beta-1 / chemistry; Receptors, Adrenergic, beta-1 / genetics; Sequence Deletion
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 article

Polymorphisms in the canine and feline renin-angiotensin-aldosterone system genes

Meurs, K. M., Chdid, L., Reina-Doreste, Y., & Stern, J. A. (2015, April). ANIMAL GENETICS, Vol. 46, pp. 226–226.

By: K. Meurs n, L. Chdid n, Y. Reina-Doreste n & J. Stern n

MeSH headings : Animals; Cats; Dogs; Polymorphism, Genetic; Renin-Angiotensin System / genetics; Sequence Analysis, DNA
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Identification of PDE5A:E90K: A Polymorphism in the Canine Phosphodiesterase 5A Gene Affecting Basal cGMP Concentrations of Healthy Dogs


By: J. Stern n, Y. Reina-Doreste n, L. Chdid n & K. Meurs n

author keywords: Individualized medicine; Pharmacogenomics; Pulmonary hypertension; Sildenafil citrate; Single nucleotide polymorphisms
MeSH headings : Amino Acid Sequence; Animals; Cyclic GMP / metabolism; Cyclic Nucleotide Phosphodiesterases, Type 5 / genetics; Cyclic Nucleotide Phosphodiesterases, Type 5 / metabolism; DNA / chemistry; DNA / genetics; Dogs / genetics; Dogs / metabolism; Molecular Sequence Data; Polymerase Chain Reaction / veterinary; Polymorphism, Single Nucleotide / genetics; Sequence Alignment; Sequence Analysis, DNA
Sources: Web Of Science, ORCID
Added: August 6, 2018