Linda Martin

White, S. R., Martin, L. D., Stern, R., Laxman, B., & Marroquin, B. A. (2010). Expression of IL-4/IL-13 receptors in differentiating human airway epithelial cells. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 299(5), L681–L693. https://doi.org/10.1152/ajplung.00422.2009

Manzo, N. D., Slade, R., Richards, J. H., McGee, J. K., Martin, L. D., & Dye, J. A. (2010). Susceptibility of Inflamed Alveolar and Airway Epithelial Cells to Injury Induced by Diesel Exhaust Particles of Varying Organic Carbon Content. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 73(8), 565–580. https://doi.org/10.1080/15287390903566625

White, S. R., Martin, L. D., Abe, M. K., Marroquin, B. A., Stern, R., & Fu, X. (2009). Insulin receptor substrate-1/2 mediates IL-4-induced migration of human airway epithelial cells. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 297(1), L164–L173. https://doi.org/10.1152/ajplung.90453.2008

Booth, B. W., Sandifer, T., Martin, E. L., & Martin, L. D. (2007). IL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17. Respiratory Research, 8.

Li, Y.-H., Martin, L. D., & Adler, K. B. (2007). Method and compositions for altering mucus secretion. Washington, DC: U.S. Patent and Trademark Office.

Chorley, B. N., Crews, A. L., Li, Y. H., Adler, K. B., Minnicozzi, M., & Martin, L. D. (2006). Differential Muc2 and Muc5ac secretion by stimulated guinea pig tracheal epithelial cells in vitro. Respiratory Research, 7, 35.

Takashi, S., Parikh, I., Adler, K. B., Martin, L. D., & Y., L. (2006). Methods for regulating inflammatory mediators and peptides useful therein. Washington, DC: U.S. Patent and Trademark Office.

Mexas, A. M., Hess, R. S., Hawkins, E. C., & Martin, L. D. (2006). Pulmonary lesions in cats with diabetes mellitus. JOURNAL OF VETERINARY INTERNAL MEDICINE, 20(1), 47–51. https://doi.org/10.1892/0891-6640(2006)20[47:PLICWD]2.0.CO;2

Martin, L. D., Adler, K. B., Macchione, M., Akley, N. J., & McKane, S. A. (2005). Culture system for mouse tracheal epithelial cells. Washington, DC: U.S. Patent and Trademark Office.

Fischer, B. M., Cuellar, J. G., Byrd, A. S., Rice, A. B., Bonner, J. C., Martin, L. D., & Voynow, J. A. (2005). ErbB2 activity is required for airway epithelial repair following neutrophil elastase exposure. FASEB Journal, 19(7).

Park, J. A., He, F., Martin, L. D., Li, Y. H., Chorley, B. N., & Adler, K. B. (2005). Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C delta-mediated mechanism. AMERICAN JOURNAL OF PATHOLOGY, 167(3), 651–661. https://doi.org/10.1016/S0002-9440(10)62040-8

Deshmukh, H. S., Case, L. M., Wesselkamper, S. C., Borchers, M. T., Martin, L. D., Shertzer, H. G., … Leikauf, G. G. D. (2005). Metalloproteinases mediate mucin 5AC expression by epidermal growth factor receptor activation. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 171(4), 305–314. https://doi.org/10.1164/rccm.200408-1003OC

Lankford, S. M., Macchione, M., Crews, A. L., McKane, S. A., Akley, N. J., & Martin, L. D. (2005). Modeling the airway epithelium in allergic asthma: Interleukin-13-induced effects in differentiated murine tracheal epithelial cells. In Vitro Cellular & Developmental Biology. Animal, 41(7), 217–224.

Willens, S., Stoskopf, M. K., Martin, L. D., & Lewbart, G. A. (2005). Viability of glycerol-preserved and cryopreserved anuran skin. In Vitro Cellular & Developmental Biology. Animal, 41(09-Aug), 258–263.

Singer, M., Martin, L. D., Vargaftig, B. B., Park, J., Gruber, A. D., Li, Y. H., & Adler, K. B. (2004). A MARCKS-related peptide blocks mucus hypersecretion in a mouse model of asthma. NATURE MEDICINE, 10(2), 193–196. https://doi.org/10.1038/nm983

Martin, L. D., Adler, K. B., & Li, Y. (2004). Blocking peptide for inflammatory cell secretion. Washington, DC: U.S. Patent and Trademark Office.

Vargaftig, B., Singer, M., Martin, L. D., Li, Y., & Adler, K. B. (2003). A myristoylated peptide directed against the N-terminal region of MARCKS protein inhibits mucin secretion in ovalbumin sensitized/challenged mice in vivo. American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A17.

Chorley, B. N., Martin, L. D., Crews, A. C., Li, Y., & Adler, K. B. (2003). Differential effects of albuterol isomers on normal human bronchial epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A205.

Krunkosky, T. M., Martin, L. D., Fischer, B. M., Voynow, J. A., & Adler, K. B. (2003). Effects of TNF alpha on expression of ICAM-1 in human airway epithelial cells in vitro: Oxidant-mediated pathways and transcription factors. FREE RADICAL BIOLOGY AND MEDICINE, 35(9), 1158–1167. https://doi.org/10.1016/S0891-5849(03)00498-2

Park, J. A., He, F., Li, Y., Martin, L. D., & Adler, K. B. (2003). Human neutrophil elastase provokes release of MUC5B mucin from normal bronchial epithelial cells in vitro via a PKC-dependent mechanism. American Journal of Respiratory and Critical Care Medicine, Vol. 167, p. A203.

Little, D., Dean, R. A., Young, K. M., McKane, S. A., Martin, L. D., Jones, S. L., & Blikslager, A. T. (2003). PI3K signaling is required for prostaglandin-induced  mucosal recovery in ischemia-injured porcine ileum. American Journal of Physiology-Gastrointestinal and Liver Physiology, 284(1), G46–G56. https://doi.org/10.1152/ajpgi.00121.2002

Booth, B. W., Newcomb, D. C., McKane, S. A., Crews, A. L., Adler, K. B., Bonner, J. C., & Martin, L. D. (2003, March). Proliferation of the airway epithelium in asthma - Are inflammatory cells required? CHEST, Vol. 123, pp. 384S–385S. https://doi.org/10.1378/chest.123.3_suppl.384S

Booth, B. W., Adler, K. B., & Martin, L. D. (2002). IL-13 induces intracellular translocation and release of TGF? in human bronchial epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 165, p. A814.

Martin, L. D., Adler, K. B., Akley, N. J., Crews, A., & Sharova, L. (2002). Secretion-competent mouse tracheal epithelial cell culture from the genetically altered mouse - Pathway analysis via gene array. Chest, 121(3), 79S. https://doi.org/10.1016/S0012-3692(15)35478-7

Booth, B., Bonner, J. C., Adler, K. B., & Martin, L. D. (2001). Autocrine production of TGFa mediates interleukin 13-induced proliferation of human airway epithelial cells during development of a mucous phenotype in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 163, p. A738.

Macchione, M., Akley, N. J., Adler, K. B., & Martin, L. D. (2001). Differentiation of murine tracheal epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 163, p. A225.

Marinakos, S. M., Anderson, M. F., Ryan, J. A., Martin, L. D., & Feldheim, D. L. (2001). Encapsulation, permeability, and cellular uptake characteristics of hollow nanometer-sized conductive polymer capsules. JOURNAL OF PHYSICAL CHEMISTRY B, 105(37), 8872–8876. https://doi.org/10.1021/jp010820d

Li, Y. H., Martin, L. D., Minnicozzi, M., Greenfeder, S., Fine, J., Pettersen, C. A., … Adler, K. B. (2001). Enhanced expression of mucin genes in a guinea pig model of allergic asthma. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 25(5), 644–651. https://doi.org/10.1165/ajrcmb.25.5.4485

Martin, L. D., Macchione, M., Bonner, J. C., Booth, B. W., Akley, N. J., & Adler, K. B. (2001). Interleukin-13 induced mucous cell hyperplasia in airway epithelium. In Cilia and mucus: from development to respiratory disease. (pp. 253–263).

Booth, B. W., Adler, K. B., Bonner, J. C., Tournier, F., & Martin, L. D. (2001). Interleukin-13 induces proliferation of human airway epithelial cells in vitro via a mechanism mediated by transforming growth factor-alpha. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 25(6), 739–743. https://doi.org/10.1165/ajrcmb.25.6.4659

Booth, B., Bonner, J., Akley, N., Macchione, M., Adler, K., & Martin, L. D. (2001, July). Interleukin-13, a mediator of subepithelial fibrosis, enhances growth factor production and proliferation in human airway epithelial cells. CHEST, Vol. 120, pp. 15S–15S. https://doi.org/10.1378/chest.120.1_suppl.S15

Li, Y., Pettersen, C. A., Martin, L. D., & Adler, K. B. (2001). MARCKS protein interaction with the cellular contractile machinery may regulate mucin secretion by human airway epithelium. American Journal of Respiratory and Critical Care Medicine, Vol. 163, p. A225.

Li, Y. H., Martin, L. D., Spizz, G., & Adler, K. B. (2001). MARCKS protein is a key molecule regulating mucin secretion by human airway epithelial cells in vitro. JOURNAL OF BIOLOGICAL CHEMISTRY, 276(44), 40982–40990. https://doi.org/10.1074/jbc.M105614200

Li, Y., Martin, L. D., & Adler, K. B. (2001). MARCKS protein: a potential modulator of airway mucin secretion. In Cilia and mucus: from development to respiratory disease. (pp. 179–193).

Zhang, L. M., Rice, A. B., Adler, K., Sannes, P., Martin, L., Gladwell, W., … Bonner, J. C. (2001). Vanadium stimulates human bronchial epithelial cells to produce heparin-binding epidermal growth factor-like growth factor - A mitogen for lung fibroblasts. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 24(2), 123–131. https://doi.org/10.1165/ajrcmb.24.2.4096

He, F., Adler, K. B., Akley, N. J., Fischer, B. M., Jiang, N., Krunkosky, T. M., & Martin, L. D. (2000). Air-liquid interface culture systems for exposure of differentiated cells to oxidant stress. In Models and methods in cell signaling and gene expression applications to oxidative stress research. (pp. 15–30).

Martin, L. D., Krunkosky, T. M., & Adler, K. B. (2000). Differential generation of intracellular oxidants by TNF? and exogenous superoxide affords distinct expression of IL-6 in human airway epithelium in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A152.

Krunkosky, T. M., Fischer, B. M., Martin, L. D., Jones, N., Akley, N. J., & Adler, K. B. (2000). Effects of TNF-alpha on expression of ICAM-1 in human airway epithelial cells in vitro - Signaling pathways controlling surface and gene expression. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 22(6), 685–692. https://doi.org/10.1165/ajrcmb.22.6.3925

Bonner, J. C., Zhang, L., Sannes, P., Martin, L., Gladwell, W., Koo, J.-S., … Adler, K. (2000). Induction of heparin-binding epidermal growth factor (HB-EGF) mRNA in normal human bronchial epithelial cells by metal-induced oxidative stress. American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A149.

Martin, L. D., Bonner, J. C., Macchione, M., Booth, B., Akley, N., & Adler, K. B. (2000). Interaction of TGF? and EGF receptor mediates IL-13 induced mucous cell hyperplasia in human airway epithelium in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A779.

Li, Y., Martin, L. D., & Adler, K. B. (2000). MARCKS protein: a key intracellular molecule controlling mucin secretion by human airway goblet cells. American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A259.

He, F., Martin, L. D., & Adler, K. B. (2000). Mechanisms of human neutrophil elastase-induced mucin hypersecretion by human airway epithelial cells in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 161, p. A155.

Adler, K. B., Li, Y., & Martin, L. D. (2000). Myristoylated alanine-rich C-kinase substrate protein: A major intracellular regulatory molecule controlling secretion of mucin by human airway goblet cells. Chest, Vol. 117, pp. 266S–267S.

Jiang, N. F., Dreher, K. L., Dye, J. A., Li, Y. H., Richards, J. H., Martin, L. D., & Adler, K. B. (2000). Residual oil fly ash induces cytotoxicity and mucin secretion by guinea pig tracheal epithelial cells via an oxidant-mediated mechanism. TOXICOLOGY AND APPLIED PHARMACOLOGY, 163(3), 221–230. https://doi.org/10.1006/taap.1999.8886

Martin, L. D., Norford, D., Voynow, J., & Adler, K. B. (2000, May). Response of human airway epithelium in vitro to inflammatory mediators - Dependence on the state of cellular differentiation. CHEST, Vol. 117, pp. 267S–267S. https://doi.org/10.1378/chest.117.5_suppl_1.267s

Li, Y., Greenfeder, S., Martin, L. D., Minnicozzi, M., Voynow, J. A., & Adler, K. B. (1999). Cloning and expression of guinea pig MUC2 and MUC5AC genes. American Journal of Respiratory and Critical Care Medicine, Vol. 159, p. A852.

Li, Y., He, F., Martin, L. D., Krunkosky, T. M., Lincoln, T. M., Cornwell, T. L., & Adler, K. B. (1999). Myristoylated alanine-rich C kinase substrate (MARCKS) is produced by human airway epithelial cells and is phosphorylated by PKC and PKG. American Journal of Respiratory and Critical Care Medicine, Vol. 159, p. A723.

Adler, K. B., Martin, L. D., Voynow, J. A., & Krunkosky, T. M. (1999). TNF? effects on human airway epithelial cells in vitro: molecular mechanisms of enhanced mucin production/secretion and ICAM-I expression. 404nOtfound, Vol. 8, p. S55.

Krunkosky, T. M., Martin, L. D., Li, Y., & Adler, K. B. (1999). TNF?-induced ICAM-1 expression in airway epithelium: involvement of IkB?. American Journal of Respiratory and Critical Care Medicine, Vol. 159, p. A184.

Martin, L. D., Krunkosky, T. M., & Adler, K. B. (1999). Transcription factor activation during oxidant-regulated interleukin-6 expression in normal human bronchial epithelium in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 159, p. A447.

Adler, K. B., Fischer, B. M., Martin, L. D., & Voynow, J. A. (1998). Effects of inflammatory mediators and drugs on mucus secretion and mucociliary function. 404nOtfound, 149, 245–248.

Martin, L. D., Krunkosky, T. M., Voynow, J. A., & Adler, K. B. (1998). Intracellular reactive oxygen and nitrogen species as signaling molecules in airway epithelium. Environmental Health Perspectives, 106, 1197–1203.

Martin, L. D., Krunkosky, T. M., Voynow, J. A., & Adler, K. B. (1998). Oxidant-regulated gene expression in inflammatory lung disease. In Acute respiratory distress syndrome: cellular and molecular mechanisms and clinical management. (pp. 187–195). https://doi.org/10.1007/978-1-4419-8634-4_23

Martin, L. D., Krunkosky, T. M., Voynow, J. A., & Adler, K. B. (1998, October). The role of reactive oxygen and nitrogen species in airway epithelial gene expression. ENVIRONMENTAL HEALTH PERSPECTIVES, Vol. 106, pp. 1197–1203. https://doi.org/10.2307/3433986

Martin, L. D., Rochelle, L. G., Fischer, B. M., Krunkosky, T. M., & Adler, K. B. (1997). [Review of Airway epithelium as an effector of inflammation: molecular regulation of secondary mediators]. EUROPEAN RESPIRATORY JOURNAL, 10(9), 2139–2146. https://doi.org/10.1183/09031936.97.10092139

Krunkosky, T. M., Martin, L. D., Fischer, B. M., & Adler, K. B. (1997). Mechanisms of TNF?-induced ICAM-1 expression in airway epithelium. American Journal of Respiratory and Critical Care Medicine, Vol. 155, p. A207.

Martin, L. D., Krunkosky, T. M., Rochelle, L. G., & Adler, K. B. (1997). TNF? and oxidant-induced expression of Interleukin-6 in normal human bronchial epithelium in vitro. American Journal of Respiratory and Critical Care Medicine, Vol. 155, p. A206.

Martin, L. D., Krunkosky, T. M., Dye, J. A., Fischer, B. M., Jiang, N. F., Rochelle, L. G., … Adler, K. B. (1997, September). The role of reactive oxygen and nitrogen species in the response of airway epithelium to particulates. ENVIRONMENTAL HEALTH PERSPECTIVES, Vol. 105, pp. 1301–1307. https://doi.org/10.2307/3433551

Adler, K. B., Krunkosky, T. M., Fischer, B. M., Rochelle, L. G., Martin, L. D., Dreher, K. L., … Dye, J. (1996). Role or reactive oxygen and nitrogen species in the response of airway epithelium to particulates. Proceedings of the 6th International Meeting of the Toxicology of Natural and Man-Made Fibrous and Non-Fibrous Particles., Vol. 6, p. 139.

Krunkosky, T. M., Fischer, B. M., Martin, L. D., & Adler, K. B. (1996). Tumor necrosis factor alpha (TNF?) provokes expression of intercellular adhesion molecule-1 (ICAM-1) on human bronchial epithelial cells in primary culture. American Journal of Respiratory and Critical Care Medicine, Vol. 153, p. A27.