Lloyd Fleisher

Goralska, M., Fleisher, L. N., & McGahan, M. C. (2017). Vitreous Humor Changes Expression of Iron-Handling Proteins in Lens Epithelial Cells. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 58(2). https://doi.org/10.1167/iovs.16-20610

Goralska, M., Fleisher, L. N., & McGahan, M. C. (2014). Hypoxia induced changes in expression of proteins involved in iron uptake and storage in cultured lens epithelial cells. EXPERIMENTAL EYE RESEARCH, 125, 135–141. https://doi.org/10.1016/j.exer.2014.05.010

Goralska, M., Nagar, S., Fleisher, L. N., Mzyk, P., & McGahan, M. C. (2013). Source-Dependent Intracellular Distribution of Iron in Lens Epithelial Cells Cultured Under Normoxic and Hypoxic Conditions. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 54(12), 7666–7673. https://doi.org/10.1167/iovs.13-12868

Harned, J., Ferrell, J., Nagar, S., Goralska, M., Fleisher, L. N., & McGahan, M. C. (2012). Ceruloplasmin alters intracellular iron regulated proteins and pathways: Ferritin, transferrin receptor, glutamate and hypoxia-inducible factor-1α. Experimental Eye Research, 97(1), 90–97. https://doi.org/10.1016/j.exer.2012.02.001

Harned, J., Ferrell, J., Lall, M. M., Fleisher, L. N., Nagar, S., Goralska, M., & McGahan, M. C. (2010). Altered Ferritin Subunit Composition: Change in Iron Metabolism in Lens Epithelial Cells and Downstream Effects on Glutathione Levels and VEGF Secretion. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 51(9), 4437–4446. https://doi.org/10.1167/iovs.09-3861

Goralska, M., Nagar, S., Colitz, C. M. H., Fleisher, L. N., & McGahan, M. C. (2009). Changes in Ferritin H- and L-Chains in Canine Lenses with Age-Related Nuclear Cataract. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 50(1), 305–310. https://doi.org/10.1167/iovs.08-2230

Goralska, M., Nagar, S., Fleisher, L. N., & McGahan, M. C. (2009). Distribution of ferritin chains in canine lenses with and without age-related nuclear cataracts. Molecular Vision, 15(256-59), 2404–2410.

Goralska, M., Ferrell, J., Harned, J., Lall, M., Nagar, S., Fleisher, L. N., & McGahan, M. C. (2009). Iron metabolism in the eye: A review. Experimental Eye Research, 88(2), 204–215. https://doi.org/10.1016/j.exer.2008.10.026

Lall, M. M., Ferrell, J., Nagar, S., Fleisher, L. N., & McGahan, M. C. (2008). Iron regulates L-cystine uptake and glutathione levels in lens epithelial and retinal pigment epithelial cells by its effect on cytosolic aconitase. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 49(1), 310–319. https://doi.org/10.1167/iovs.07-1041

Goralska, M., Fleisher, L. N., & McGahan, M. C. (2007). Ferritin H- and L-chains in fiber cell canine and human lenses of different ages. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 48(9), 3968–3975. https://doi.org/10.1167/iovs.07-0130

Harned, J., Fleisher, L. N., & McGahan, M. C. (2006). Lens epithelial cells synthesize and secrete ceruloplasmin: Effects of ceruloplasmin and transferrin on iron efflux and intracellular iron dynamics. EXPERIMENTAL EYE RESEARCH, 83(4), 721–727. https://doi.org/10.1016/j.exer.2006.01.018

Goralska, M., Nagar, S., Fleisher, L. N., & McGahan, M. C. (2005). Differential degradation of ferritin H- and L-chains: Accumulation of L-chain-rich ferritin in lens epithelial cells. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 46(10), 3521–3529. https://doi.org/10.1167/iovs.05-0358

McGahan, M. C., Harned, J., Mukunnemkeril, M., Goralska, M., Fleisher, L., & Ferrell, J. B. (2005). Iron alters glutamate secretion by regulating cytosolic aconitase activity. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 288(5), C1117–C1124. https://doi.org/10.1152/ajpcell.00444.2004

Fleisher, L. N., McGahan, M. C., & Ferrell, J. B. (2000). Rabbit pigmented ciliary epithelium produces interleukin-6 in response to inflammatory cytokines. EXPERIMENTAL EYE RESEARCH, 70(3), 271–279. https://doi.org/10.1006/exer.1999.0787

Goralska, M., Harned, J., Fleisher, L. N., & McGahan, M. C. (1998). The effect of ascorbic acid and ferric ammonium citrate on iron uptake and storage in lens epithelial cells. EXPERIMENTAL EYE RESEARCH, 66(6), 687–697. https://doi.org/10.1006/exer.1997.0466

Allen, J. B., Davidson, M. G., Nasisse, M. P., Fleisher, L. N., & McGahan, M. C. (1998). The lens influences aqueous humor levels of transforming growth factor-beta 2. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 236(4), 305–311. https://doi.org/10.1007/s004170050083

Goralska, M., Harned, J., Grimes, A. M., Fleisher, L. N., & McGahan, M. C. (1997). Mechanisms by which ascorbic acid increases ferritin levels in cultured lens epithelial cells. EXPERIMENTAL EYE RESEARCH, 64(3), 413–421. https://doi.org/10.1006/exer.1996.0227

Allen, J. B., McGahan, M. C., Fleisher, L. N., Jaffe, G. J., & Privalle, C. T. (1997). Nitric oxide in ocular inflammation. In Advances in ocular toxicology (pp. 121–131). https://doi.org/10.1007/978-1-4615-5937-5_16

McGahan, M. C., Grimes, A. M., & Fleisher, L. N. (1996). Hemoglobin exacerbates the ocular inflammatory response to endotoxin. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 234(10), 643–647. https://doi.org/10.1007/BF00185299

Fleisher, L. N., McGahan, M. C., Ferrell, J. B., & Pagan, I. (1996). Interleukin-1 beta increases prostaglandin E(2)-stimulated adenosine 3',5'-cyclic monophosphate production in rabbit pigmented ciliary epithelium. EXPERIMENTAL EYE RESEARCH, 63(1), 91–104. https://doi.org/10.1006/exer.1996.0095

Allen, J. B., McGahan, M. C., Ogawa, Y., Sellon, D. C., Clark, B. D., & Fleisher, L. N. (1996). Intravitreal transforming growth factor-beta 2 decreases cellular infiltration in endotoxin-induced ocular inflammation in rabbits. CURRENT EYE RESEARCH, 15(1), 95–103. https://doi.org/10.3109/02713689609017616

Allen, J. B., McGahan, M. C., Ferrell, J. B., Adler, K. B., & Fleisher, L. N. (1996). Nitric oxide synthase inhibitors exert differential time-dependent effects on LPS-induced uveitis. EXPERIMENTAL EYE RESEARCH, 62(1), 21–28. https://doi.org/10.1006/exer.1996.0003

FLEISHER, L. N., FERRELL, J. B., & MCGAHAN, M. C. (1995). INFLAMMATION-INDUCED CHANGES IN ADENOSINE 3',5'-CYCLIC-MONOPHOSPHATE PRODUCTION BY CILIARY EPITHELIAL-CELL BILAYERS. EXPERIMENTAL EYE RESEARCH, 60(2), 165–171. https://doi.org/10.1016/S0014-4835(95)80007-7

MCGAHAN, M. C., GRIMES, A. M., NASISSE, M. P., & FLEISHER, L. N. (1995). IRON UPTAKE BY CULTURED LENS EPITHELIAL-CELLS. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 233(6), 354–359. https://doi.org/10.1007/BF00200484

FLEISHER, L., FERRELL, J., & MCGAHAN, C. (1995). MEDIATORS OF THE OCULAR INFLAMMATORY RESPONSE TO INTERLEUKIN-1-BETA PLUS TUMOR-NECROSIS-FACTOR-ALPHA. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 233(2), 94–100. https://doi.org/10.1007/BF00241479

MCGAHAN, M. C., HARNED, J., GORALSKA, M., SHERRY, B., & FLEISHER, L. N. (1995). TRANSFERRIN SECRETION BY LENS EPITHELIAL-CELLS IN CULTURE. EXPERIMENTAL EYE RESEARCH, 60(6), 667–673. https://doi.org/10.1016/S0014-4835(05)80008-9

ECHELMAN, D. A., NASISSE, M. P., SHIELDS, M. B., MCGAHAN, M. C., & FLEISHER, L. N. (1994). INFLUENCE OF EXPOSURE TIME ON INFLAMMATORY RESPONSE TO NEODYMIUM - YAG CYCLOPHOTOCOAGULATION IN RABBITS. ARCHIVES OF OPHTHALMOLOGY, 112(7), 977–981. https://doi.org/10.1001/archopht.1994.01090190125032

MCGAHAN, M. C., HARNED, J., GRIMES, A. M., & FLEISHER, L. N. (1994). REGULATION OF FERRITIN LEVELS IN CULTURED LENS EPITHELIAL-CELLS. EXPERIMENTAL EYE RESEARCH, 59(5), 551–555. https://doi.org/10.1006/exer.1994.1140

MCGAHAN, M. C., GRIMES, A. M., & FLEISHER, L. N. (1994, April). TRANSFERRIN INHIBITS THE OCULAR INFLAMMATORY RESPONSE. https://doi.org/10.1006/exer.1994.1044

MCGAHAN, M. C., & FLEISHER, L. N. (1992). CELLULAR-RESPONSE TO INTRAVITREAL INJECTION OF ENDOTOXIN AND XANTHINE-OXIDASE IN RABBITS. GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 230(5), 463–467. https://doi.org/10.1007/BF00175935

Ferrell, J. B., Fleisher, L. N., Smith, M. G., & McGahan, M. C. (1992). Effects of copper loading and depletion on rabbit superoxide dismutase activity. Trace Elements in Medicine, 9, 55–58.

Fleisher, L. N., Ferrell, J. B., & McGahan, M. C. (1992). Synergistic uveitic effects of tumor necrosis factor-alpha and interleukin-1 beta. Investigative Ophthalmology and Visual Science, 33, 2120–2127.

MCGAHAN, M. C., FLEISHER, L. N., & GRIMES, A. M. (1991). EFFECTS OF COPPER DEPLETION AND D-PENICILLAMINE TREATMENT ON THE OCULAR INFLAMMATORY RESPONSE. AGENTS AND ACTIONS, 34(3-4), 405–409. https://doi.org/10.1007/bf01988736

Fleisher, L. N., Ferrell, J. B., & McGahan, M. C. (1991). Lipid mediators of TNF- induced uveitis. Investigative Ophthalmology and Visual Science, 32, 2393–2399.

FLEISHER, L. N., FERRELL, J. B., & MCGAHAN, M. C. (1990). OCULAR INFLAMMATORY EFFECTS OF INTRAVITREALLY INJECTED TUMOR NECROSIS FACTOR-ALPHA AND ENDOTOXIN. INFLAMMATION, 14(3), 325–335. https://doi.org/10.1007/BF00915816

MCGAHAN, M. C., FLEISHER, L. N., & GRIMES, A. M. (1989). CLINICAL SIGNS OF ACUTE OCULAR INFLAMMATORY RESPONSE TO ENDOTOXIN ARE NOT ALTERED BY INCREASING ANTIOXIDANT POTENCY OF INTRAOCULAR FLUIDS. INFLAMMATION, 13(4), 393–400. https://doi.org/10.1007/BF00914923

FLEISHER, L. N., FERRELL, J. B., OLSON, N. C., & MCGAHAN, M. C. (1989). DIMETHYLTHIOUREA INHIBITS THE INFLAMMATORY RESPONSE TO INTRAVITREALLY-INJECTED ENDOTOXIN. EXPERIMENTAL EYE RESEARCH, 48(4), 561–567. https://doi.org/10.1016/0014-4835(89)90038-9

McGahan, M. C., Grimes, A. M., & Fleisher, L. N. (1989). Ferroxidase activity increases dramatically in the aqueous humor during the ocular inflammatory response. Ophthalmic Research, 21, 221–225. https://doi.org/10.1159/000266811

McGahan, M. C., & Fleisher, L. N. (1988). Inflammation-induced changes in the concentration of iron and total-iron-binding capacity in the intraocular fluids of rabbits. Graefes Archive for Clinical and Experimental Ophthalmology, 226, 27–30. https://doi.org/10.1007/BF02172712

MCGAHAN, M. C., & FLEISHER, L. N. (1986). A MICROMETHOD FOR THE DETERMINATION OF IRON AND TOTAL IRON-BINDING-CAPACITY IN INTRAOCULAR FLUIDS AND PLASMA USING ELECTROTHERMAL ATOMIC-ABSORPTION SPECTROSCOPY. ANALYTICAL BIOCHEMISTRY, 156(2), 397–402. https://doi.org/10.1016/0003-2697(86)90271-X

MCGAHAN, M. C., & FLEISHER, L. N. (1986). ANTIOXIDANT ACTIVITY OF AQUEOUS AND VITREOUS-HUMOR FROM THE INFLAMED RABBIT EYE. CURRENT EYE RESEARCH, 5(9), 641–645. https://doi.org/10.3109/02713688609015131

FLEISHER, L. N., & MCGAHAN, M. C. (1986). TIME COURSE FOR PROSTAGLANDIN SYNTHESIS BY RABBIT LENS DURING ENDOTOXIN-INDUCED OCULAR INFLAMMATION. CURRENT EYE RESEARCH, 5(9), 629–634. https://doi.org/10.3109/02713688609015129

FLEISHER, L. N., & MCGAHAN, M. C. (1985). ENDOTOXIN-INDUCED OCULAR INFLAMMATION INCREASES PROSTAGLANDIN-E2 SYNTHESIS BY RABBIT LENS. EXPERIMENTAL EYE RESEARCH, 40(5), 711–719. https://doi.org/10.1016/0014-4835(85)90140-X