Works (43)

Updated: December 2nd, 2023 05:01

2023 journal article

Antimicrobial Properties of Equine Stromal Cells and Platelets and Future Directions

VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE, 39(3), 565โ€“578.

By: L. Pezzanite, L. Chow, S. Dow, L. Goodrich, J. Gilbertie & L. Schnabel

author keywords: Horse; Antimicrobial; Regenerative; Biologic; Therapies; Mesenchymal stromal cells; Platelets
Source: Web Of Science
Added: November 27, 2023

2023 article

Considerations for the Use of Biologic and Regenerative Therapies in Equine Practice

Schnabel, L. V. (2023, December). VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE, Vol. 39, pp. XIII-XIV.

By: L. Schnabel n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Source: Web Of Science
Added: November 27, 2023

2023 article

Effect of gentamicin on CD3+T-lymphocyte proliferation for treatment of equine recurrent uveitis: An in vitro study

Smith, H. L., Berglund, A. K., Robertson, J. B., Schnabel, L. V., McMullen, R. J., Gilger, B. C., & Oh, A. (2023, April 28). VETERINARY OPHTHALMOLOGY, Vol. 4.

By: H. Smithโ€‰ n, A. Berglund n, J. Robertson nโ€‰, L. Schnabel n, R. McMullenโ€‰*, B. Gilger nโ€‰, A. Oh nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: autoimmune disease; equine recurrent uveitis; gentamicin; horse; immunology; intravitreal injection
Sources: Web Of Science, ORCID
Added: April 29, 2023

2023 journal article

Pneumatic compression therapy using the EQ Press accelerates lymphatic flow in healthy equine forelimbs as determined by lymphoscintigraphy

AMERICAN JOURNAL OF VETERINARY RESEARCH, 84(4).

By: D. Koch n, L. Schnabel n, J. Reynolds n & C. Berry n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Horses; Animals; Lymphoscintigraphy / veterinary; Technetium Tc 99m Sulfur Colloid; Lymph Nodes; Lymphedema / diagnostic imaging; Lymphedema / therapy; Lymphedema / veterinary; Forelimb / diagnostic imaging; Radiopharmaceuticals; Horse Diseases / pathology
Source: Web Of Science
Added: May 22, 2023

2022 journal article

A Platelet-Rich Plasma-Derived Biologic Clears Staphylococcus aureus Biofilms While Mitigating Cartilage Degeneration and Joint Inflammation in a Clinically Relevant Large Animal Infectious Arthritis Model

Frontiers in Cellular and Infection Microbiology, 12.

By: J. Gilbertie n, T. Schaer*, J. Engilesโ€‰*, G. Seiler n, B. Deddens n, A. Schubert n, M. Jacob n, D. Stefanovskiโ€‰* ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: infectious arthritis; S; aureus; biofilm; antimicrobial; platelets; cartilage; synovium; synovial fluid
MeSH headings : Amikacin; Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Arthritis, Infectious / drug therapy; Biofilms; Biological Products; Disease Models, Animal; Horses; Inflammation; Platelet-Rich Plasma; Staphylococcal Infections / drug therapy; Staphylococcal Infections / veterinary; Staphylococcus aureus
Sources: Web Of Science, Crossref, ORCID
Added: June 20, 2022

2022 article

Alterations to the synovial invaginations of the navicular bone are associated with pathology of both the navicular apparatus and distal interphalangeal joint when evaluated using high field MRI

McParland, T. J., Horne, C. R., Robertson, J. B., Schnabel, L. V., & Nelson, N. C. (2022, August 15). VETERINARY RADIOLOGY & ULTRASOUND, Vol. 8.

By: T. McParland n, C. Horne n, J. Robertson nโ€‰, L. Schnabel n & N. Nelson n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: distal sesamoid bone; foot; horse; imaging
MeSH headings : Animals; Horses; Retrospective Studies; Joints; Tarsal Bones / diagnostic imaging; Magnetic Resonance Imaging / veterinary; Foot; Horse Diseases
Sources: Web Of Science, ORCID
Added: August 22, 2022

2022 journal article

Interleukin-1 beta in tendon injury enhances reparative gene and protein expression in mesenchymal stem cells

FRONTIERS IN VETERINARY SCIENCE, 9.

By: D. Koch n, A. Berglund n, K. Messenger n, J. Gilbertie n, I. Ellis n & L. Schnabel n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: tendon; cytokine; ultrafiltration probe; mesenchymal stem cell; licensing
Source: Web Of Science
Added: December 12, 2022

2022 article

Leveraging MRI characterization of longitudinal tears of the deep digital flexor tendon in horses using machine learning

ELKhamary, A. N., Keenihan, E. K., Schnabel, L. V., Redding, W. R., & Schumacher, J. (2022, April 12). VETERINARY RADIOLOGY & ULTRASOUND.

By: A. ELKhamary*, E. Keenihan n, L. Schnabel n, W. Redding n & J. Schumacher*

co-author countries: Egypt ๐Ÿ‡ช๐Ÿ‡ฌ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: equine; feature extraction; longitudinal tear grading; machine learning classifier; tenoscopy
MeSH headings : Animals; Horse Diseases / diagnosis; Horses; Machine Learning; Magnetic Resonance Imaging / veterinary; Retrospective Studies; Tendons / diagnostic imaging
Source: Web Of Science
Added: April 25, 2022

2022 article

Non-steroidal anti-inflammatory drugs in equine orthopaedics

Jacobs, C. C., Schnabel, L. V., McIlwraith, C. W., & Blikslager, A. T. (2022, February 10). EQUINE VETERINARY JOURNAL, Vol. 2.

By: C. Jacobs n, L. Schnabel n, C. McIlwraithโ€‰* & A. Blikslager nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: horse; non-steroidal anti-inflammatory drug; orthopaedics; osteoarthritis
Sources: Web Of Science, ORCID
Added: February 28, 2022

2022 journal article

Potent Activity of Ertapenem Plus Cefazolin Within Staphylococcal Biofilms: A Contributing Factor in the Treatment of Methicillin-Susceptible Staphylococcus aureus Endocarditis

OPEN FORUM INFECTIOUS DISEASES, 9(5).

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: cefazolin; ertapenem; endocarditis; Staphylococcus aureus
Source: Web Of Science
Added: May 10, 2022

2022 journal article

TGF-beta 2 enhances expression of equine bone marrow-derived mesenchymal stem cell paracrine factors with known associations to tendon healing

STEM CELL RESEARCH & THERAPY, 13(1).

By: D. Koch n, L. Schnabel n, I. Ellis n, R. Bates n & A. Berglund n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Mesenchymal stem cell; Tenocyte; TGF-beta 2; Equine; Tendon; RNA-sequencing; Paracrine factors; Extracellular matrix
MeSH headings : Animals; Bone Marrow / metabolism; Collagen Type I / metabolism; Cytokines / metabolism; Horses; Mesenchymal Stem Cells / metabolism; Paracrine Communication; RNA / metabolism; Tenascin / genetics; Tenascin / metabolism; Tendons / metabolism; Transforming Growth Factor beta2 / genetics; Transforming Growth Factors / metabolism
Source: Web Of Science
Added: September 26, 2022

2022 article

TLR-activated mesenchymal stromal cell therapy and antibiotics to treat multi-drug resistant Staphylococcal septic arthritis in an equine model

Pezzanite, L. M., Chow, L., Phillips, J., Griffenhagen, G. M., Moore, A. R., Schaer, T. P., โ€ฆ Goodrich, L. R. (2022, September 23). ANNALS OF TRANSLATIONAL MEDICINE.

By: L. Pezzanite, L. Chow, J. Phillips, G. Griffenhagen, A. Moore, T. Schaer, J. Engiles, N. Werpy ...

author keywords: Antibiotic resistance; infectious arthritis; mesenchymal stromal cell (MSC)
Source: Web Of Science
Added: November 28, 2022

2022 article

Tendon sheath masses - What are the differential diagnoses and what diagnostics are needed?

Schnabel, L. V., Horne, C. R., & Jacobs, C. C. (2022, June 13). EQUINE VETERINARY EDUCATION.

By: L. Schnabel n, C. Horne n & C. Jacobs n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Source: Web Of Science
Added: June 27, 2022

2021 journal article

Adeno-Associated Virus-Mediated Overexpression of Interleukin-10 Affects the Immunomodulatory Properties of Equine Bone Marrow-Derived Mesenchymal Stem Cells

HUMAN GENE THERAPY, 32(17-18), 907โ€“918.

By: A. Cameron*, K. Even*, R. Linardi*, A. Berglund n, L. Schnabel n, J. Engilesโ€‰*, K. Ortvedโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: osteoarthritis; PTOA; immunomodulation; mesenchymal stem cell; IL-10; AAV
MeSH headings : Animals; Bone Marrow; Cells, Cultured; Dependovirus / genetics; Horses; Interleukin-10 / genetics; Mesenchymal Stem Cells
Source: Web Of Science
Added: May 24, 2021

2021 journal article

Cross-matching of allogeneic mesenchymal stromal cells eliminates recipient immune targeting

STEM CELLS TRANSLATIONAL MEDICINE, 10(5), 694โ€“710.

By: A. Rowland*, D. Millerโ€‰*, A. Berglund n, L. Schnabel n, G. Levine*, D. Antczak*, A. Watts*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: allogeneic; alloimmunization; antibody; autologous; cross‐ match; humoral; innate; intra‐ articular; major histocompatibility complex (MHC); MSC
MeSH headings : Adaptive Immunity; Allografts; Animals; Chemokine CXCL12; Histocompatibility Testing / veterinary; Horses; Immunity, Innate; Major Histocompatibility Complex; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Synovial Fluid / immunology; Transplantation, Autologous
Source: Web Of Science
Added: January 11, 2021

2021 article

Effects of continuous passage on the immunomodulator properties of equine bone marrow-derived mesenchymal stem cells in vitro (vol 234, 110203, 2021)

Connard, S. S., Linardi, R. L., Even, K. M., Berglund, A. K., Schnabel, L. V., & Ortved, K. F. (2021, December). VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, Vol. 242.

By: S. Connardโ€‰*, R. Linardi*, K. Even*, A. Berglund n, L. Schnabel n & K. Ortvedโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Source: Web Of Science
Added: March 7, 2022

2021 journal article

Effects of continuous passage on the immunomodulatory properties of equine bone marrow-derived mesenchymal stem cells in vitro

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 234.

By: S. Connardโ€‰*, R. Linardi*, K. Even*, A. Berglund n, L. Schnabel n & K. Ortvedโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Horse; Mesenchymal stem cells; Continuous passage; Immunomodulation
MeSH headings : Animals; Bone Marrow Cells / drug effects; Bone Marrow Cells / immunology; Bone Marrow Cells / physiology; Cell Differentiation / drug effects; Cell Differentiation / immunology; Cell Proliferation / drug effects; Cells, Cultured; Cytokines / analysis; Cytokines / biosynthesis; Cytokines / immunology; Female; Horses; Immunomodulation; In Vitro Techniques; Interferon-gamma / pharmacology; Lymphocyte Activation / drug effects; Lymphocyte Activation / immunology; Male; Mesenchymal Stem Cells / immunology; Mesenchymal Stem Cells / physiology
Source: Web Of Science
Added: October 12, 2021

2021 journal article

Pathology in Practice

Journal of the American Veterinary Medical Association, 258(9), 961โ€“964.

By: A. DiDomenico n, A. Fowler n, C. Horne n, P. Bizikova n, L. Schnabel n & D. Stowe nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals
Sources: Web Of Science, Crossref, ORCID
Added: June 10, 2021

2021 journal article

TGF-beta 2 Reduces the Cell-Mediated Immunogenicity of Equine MHC-Mismatched Bone Marrow-Derived Mesenchymal Stem Cells Without Altering Immunomodulatory Properties

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 9.

By: A. Berglund n, J. Long n, J. Robertson nโ€‰ & L. Schnabel n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: mesenchymal stem cell; TGF-β 2; cytotoxicity; immunogenicity; major histocompatibility complex; allogeneic
Sources: Web Of Science, ORCID
Added: March 8, 2021

2021 journal article

The combination of mitogenic stimulation and DNA damage induces chondrocyte senescence

OSTEOARTHRITIS AND CARTILAGE, 29(3), 402โ€“412.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: SA-beta-gal; DNA damage; Osteoarthritis; Aging; TGF- beta 1; bFGF
MeSH headings : Animals; Ankle Joint; Cartilage, Articular / cytology; Cartilage, Articular / drug effects; Cartilage, Articular / metabolism; Cellular Senescence / drug effects; Cellular Senescence / genetics; Chemokine CCL2 / drug effects; Chemokine CCL2 / genetics; Chondrocytes / drug effects; Chondrocytes / metabolism; Cyclin-Dependent Kinase Inhibitor p16 / drug effects; Cyclin-Dependent Kinase Inhibitor p16 / metabolism; DNA Damage / genetics; Fibroblast Growth Factor 2 / pharmacology; Gene Expression / drug effects; Histones / drug effects; Histones / metabolism; Horses; Humans; In Vitro Techniques; Inflammation / genetics; Insulin-Like Growth Factor Binding Protein 3 / drug effects; Insulin-Like Growth Factor Binding Protein 3 / genetics; Interleukin-6 / genetics; Matrix Metalloproteinase 13 / drug effects; Matrix Metalloproteinase 13 / genetics; Mitogens / pharmacology; Stifle; Transforming Growth Factor beta1 / pharmacology; beta-Galactosidase / drug effects; beta-Galactosidase / metabolism
Source: Web Of Science
Added: March 29, 2021

2020 journal article

Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

NATURE COMMUNICATIONS, 11(1).

By: P. Dinh n, D. Paudel n, H. Brochu n, K. Popowski nโ€‰, M. Gracieux n, J. Cores n, K. Huang nโ€‰, M. Hensley n ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Administration, Inhalation; Alveolar Epithelial Cells / drug effects; Alveolar Epithelial Cells / metabolism; Alveolar Epithelial Cells / pathology; Animals; Apoptosis / drug effects; Bleomycin / toxicity; Cell Proliferation; Disease Models, Animal; Exosomes / metabolism; Exosomes / transplantation; Humans; Idiopathic Pulmonary Fibrosis / chemically induced; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Idiopathic Pulmonary Fibrosis / therapy; Lung / cytology; Lung / metabolism; Lung Injury / chemically induced; Lung Injury / metabolism; Lung Injury / pathology; Lung Injury / therapy; Mesenchymal Stem Cells / metabolism; Mice; Myofibroblasts / cytology; Proteomics; Silicon Dioxide / toxicity; Spheroids, Cellular / metabolism
Sources: Web Of Science, ORCID
Added: March 23, 2020

2020 journal article

One health in regenerative medicine: report on the second Havemeyer symposium on regenerative medicine in horses

REGENERATIVE MEDICINE, 15(6), 1775โ€“1787.

By: L. Fortierโ€‰*, L. Goodrichโ€‰*, I. Ribitsch, L. Schnabel n, D. Shepard*, A. Watts*, R. Smithโ€‰*

co-author countries: United Kingdom of Great Britain and Northern Ireland ๐Ÿ‡ฌ๐Ÿ‡ง United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: animal model; bone marrow concentrate; horse; interleukin-1 receptor antagonist protein; mesenchymal stem cell; platelet rich plasma; stem cell
MeSH headings : Animals; Cell Differentiation; Congresses as Topic; Horse Diseases / therapy; Horses; Mesenchymal Stem Cell Transplantation / methods; Mesenchymal Stem Cells / cytology; One Health; Regenerative Medicine
Source: Web Of Science
Added: August 31, 2020

2020 journal article

Platelet-rich plasma lysate displays antibiofilm properties and restores antimicrobial activity against synovial fluid biofilms in vitro

JOURNAL OF ORTHOPAEDIC RESEARCH, 38(6), 1365โ€“1374.

By: J. Gilbertie n, T. Schaerโ€‰*, A. Schubert n, M. Jacob n, S. Menegatti nโ€‰, R. Lavoie n, L. Schnabel n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: biofilms; equine model; infectious arthritis; platelet-rich plasma; Staphylococcus aureus
MeSH headings : Aminoglycosides / pharmacology; Animals; Anti-Bacterial Agents / pharmacology; Arthritis, Infectious / drug therapy; Biofilms / drug effects; Female; Horses; Male; Molecular Weight; Platelet-Rich Plasma; Synovial Fluid / microbiology
Sources: Web Of Science, ORCID
Added: January 27, 2020

2019 article

5-Benzylidene-4-Oxazolidinones Are Synergistic with Antibiotics for the Treatment of Staphylococcus aureus Biofilms

CHEMBIOCHEM, Vol. 12.

By: B. Frohock n, J. Gilbertie n, J. Daiker n, L. Schnabel n & J. Pierce nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Acinetobacter baumannii / drug effects; Anti-Bacterial Agents / pharmacology; Benzylidene Compounds / pharmacology; Biofilms / drug effects; Drug Synergism; Methicillin-Resistant Staphylococcus aureus / drug effects; Microbial Sensitivity Tests; Oxazolidinones / pharmacology; Staphylococcus aureus / physiology; Structure-Activity Relationship
Sources: Web Of Science, ORCID
Added: January 13, 2020

2019 journal article

Effects of acellular equine amniotic allografts on the healing of experimentally induced full-thickness distal limb wounds in horses

VETERINARY SURGERY, 48(8), 1416โ€“1428.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Allografts; Amnion; Animals; Bandages / veterinary; Granulation Tissue / physiology; Horse Diseases / therapy; Horses / injuries; Prospective Studies; Skin / injuries; Skin / pathology; Wound Healing / physiology; Wounds and Injuries / therapy; Wounds and Injuries / veterinary
Source: Web Of Science
Added: August 26, 2019

2019 journal article

Equine or porcine synovial fluid as a novel ex vivo model for the study of bacterial free-floating biofilms that form in human joint infections

PLOS ONE, 14(8).

By: J. Gilbertie, L. Schnabel*, N. Hickok, M. Jacob*, B. Conlon, I. Shapiro, J. Parvizi, T. Schaer

MeSH headings : Animals; Arthritis / microbiology; Arthritis / pathology; Biofilms / growth & development; Disease Models, Animal; Horses; Humans; Staphylococcal Infections / microbiology; Staphylococcal Infections / pathology; Staphylococcus aureus / physiology; Swine; Synovial Fluid / microbiology
Source: Web Of Science
Added: September 30, 2019

2019 journal article

Oral reserpine administration in horses results in low plasma concentrations that alter platelet biology

EQUINE VETERINARY JOURNAL, 51(4), 537โ€“543.

By: J. Gilbertieโ€‰ n, J. Davis*, G. Davidson n, A. McDonald n, J. Schirmer n & L. Schnabel n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: horse; reserpine; pharmacokinetics; tranquilisation; platelets; hypercoagulability
MeSH headings : Administration, Oral; Adrenergic Uptake Inhibitors / administration & dosage; Adrenergic Uptake Inhibitors / blood; Adrenergic Uptake Inhibitors / pharmacokinetics; Adrenergic Uptake Inhibitors / pharmacology; Animals; Area Under Curve; Blood Platelets / drug effects; Female; Half-Life; Horses / blood; Male; Reserpine / administration & dosage; Reserpine / blood; Reserpine / pharmacokinetics; Reserpine / pharmacology
Source: Web Of Science
Added: July 22, 2019

2018 review

Diagnosis and management of proximal sesamoid bone fractures in the horse

[Review of ]. EQUINE VETERINARY EDUCATION, 30(8), 450โ€“455.

By: L. Schnabel n & W. Redding n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: horse; proximal sesamoid bone; fracture; arthroscopy
Source: Web Of Science
Added: August 6, 2018

2018 journal article

Gram-negative multi-drug resistant bacteria influence survival to discharge for horses with septic synovial structures: 206 Cases (2010-2015)

VETERINARY MICROBIOLOGY, 226, 64โ€“73.

By: J. Gilbertie, L. Schnabel n, D. Stefanovski, D. Kelly, M. Jacob n & T. Schaer

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Septic synovitis; Infectious arthritis; Equine; Multi-drug resistance (MDR); Fluoroquinolones; Gram-negative bacteria
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Arthritis, Infectious / microbiology; Arthritis, Infectious / veterinary; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae / drug effects; Enterobacteriaceae Infections / mortality; Enterobacteriaceae Infections / veterinary; Gram-Negative Bacteria / drug effects; Gram-Negative Bacterial Infections / mortality; Gram-Negative Bacterial Infections / veterinary; Horse Diseases / microbiology; Horse Diseases / mortality; Horses; Hospitals, Animal; Microbial Sensitivity Tests; Patient Discharge / statistics & numerical data; Pseudomonas aeruginosa / drug effects; Staphylococcus / drug effects; Synovial Fluid / cytology; Synovial Fluid / microbiology; Synovitis / microbiology; Synovitis / veterinary
Source: Web Of Science
Added: December 3, 2018

2018 journal article

Inflammatory licensed equine MSCs are chondroprotective and exhibit enhanced immunomodulation in an inflammatory environment

STEM CELL RESEARCH & THERAPY, 9.

By: J. Cassanoโ€‰*, L. Schnabel n, M. Goodale* & L. Fortierโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Mesenchymal stem cells; Immunomodulation; Inflammatory licensing; Licensing; Polarization; Regenerative medicine
MeSH headings : Animals; Cells, Cultured; Chondrocytes / metabolism; Cytokines / genetics; Cytokines / metabolism; Extracellular Matrix Proteins / genetics; Extracellular Matrix Proteins / metabolism; Female; Histocompatibility Antigens Class I / genetics; Histocompatibility Antigens Class I / metabolism; Histocompatibility Antigens Class II / genetics; Histocompatibility Antigens Class II / metabolism; Horses; Immunomodulation; Macrophages / immunology; Male; Mesenchymal Stem Cells / immunology
Source: Web Of Science
Added: August 6, 2018

2018 journal article

Pooled Platelet-Rich Plasma Lysate Therapy Increases Synoviocyte Proliferation and Hyaluronic Acid Production While Protecting Chondrocytes From Synoviocyte-Derived Inflammatory Mediators

FRONTIERS IN VETERINARY SCIENCE, 5.

By: J. Gilbertieโ€‰ n, J. Long n, A. Schubert n, A. Berglund n, T. Schaerโ€‰* & L. Schnabel n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: platelet-rich plasma lysate; osteoarthritis; IL-1 beta; LPS; HA; collagen type II; aggrecan; MMP-13
Source: Web Of Science
Added: December 17, 2018

2018 journal article

The immunomodulatory function of equine MSCs is enhanced by priming through an inflammatory microenvironment or TLR3 ligand

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 195, 33โ€“39.

By: J. Cassanoโ€‰*, L. Schnabel n, M. Goodale* & L. Fortierโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Mesenchymal stem cells; MSC; Immunomodulation; TLR; Polarization; Regenerative medicine
MeSH headings : Animals; Coculture Techniques / veterinary; Female; Gene Expression Regulation; Horses / immunology; Immunomodulation / immunology; Immunomodulation / physiology; Inflammation / immunology; Inflammation / physiopathology; Inflammation / veterinary; Lymphocytes / immunology; Lymphocytes / physiology; Macrophages / immunology; Macrophages / physiology; Male; Mesenchymal Stem Cells / immunology; Mesenchymal Stem Cells / physiology; T-Lymphocytes / immunology; T-Lymphocytes / physiology; Toll-Like Receptor 3 / physiology
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Allogeneic major histocompatibility complex-mismatched equine bone marrow-derived mesenchymal stem cells are targeted for death by cytotoxic anti-major histocompatibility complex antibodies

EQUINE VETERINARY JOURNAL, 49(4), 539โ€“544.

By: A. Berglund n & L. Schnabel n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: horse; mesenchymal stem cell; allogeneic; major histocompatibility complex-mismatched; antibody response; complement-dependent cytotoxicity
MeSH headings : Animals; Antibodies / immunology; Antibody Formation / immunology; Bone Marrow; Bone Marrow Cells / cytology; Bone Marrow Cells / immunology; Horses; Major Histocompatibility Complex / immunology; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / immunology
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Effect of bone marrow-derived mesenchymal stem cells and stem cell supernatant on equine corneal wound healing in vitro

Stem Cell Research & Therapy, 8(1).

By: A. Sherman n, B. Gilger nโ€‰, A. Berglund n & L. Schnabel n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Mesenchymal stem cells; Equine; Corneal wound healing; Corneal stromal cells/fibroblasts; Scratch assay; TGF-beta 1
MeSH headings : Animals; Biomarkers / metabolism; Bone Marrow Cells / cytology; Corneal Injuries / pathology; Corneal Injuries / therapy; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor / metabolism; Female; Flow Cytometry; Horses; Male; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / metabolism; Transforming Growth Factor beta1 / metabolism; Wound Healing
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2016 journal article

Navigational ultrasound imaging: A novel imaging tool for aiding interventional therapies of equine musculoskeletal injuries

EQUINE VETERINARY JOURNAL, 48(2), 195โ€“200.

By: M. Lustgarten n, W. Redding n, L. Schnabel n, T. Prange n & G. Seiler n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: horse; navigational ultrasound imaging; fusion imaging; musculoskeletal; MRI
MeSH headings : Animals; Forelimb; Hindlimb; Horse Diseases / diagnosis; Horse Diseases / diagnostic imaging; Horse Diseases / surgery; Horses; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging / veterinary; Musculoskeletal Diseases / diagnostic imaging; Musculoskeletal Diseases / pathology; Musculoskeletal Diseases / surgery; Musculoskeletal Diseases / veterinary; Tomography, X-Ray Computed / veterinary; Ultrasonography
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Equine allogeneic bone marrow-derived mesenchymal stromal cells elicit antibody responses in vivo

STEM CELL RESEARCH & THERAPY, 6.

By: L. Pezzaniteโ€‰*, L. Fortierโ€‰*, D. Antczak*, J. Cassanoโ€‰*, M. Brosnahanโ€‰*, D. Miller*, L. Schnabel n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Antibodies / immunology; Antibody Formation / immunology; Bone Marrow Cells / cytology; Bone Marrow Cells / immunology; Female; Horses; Inflammation / immunology; Major Histocompatibility Complex / immunology; Male; Mesenchymal Stem Cell Transplantation / methods; Mesenchymal Stem Cells / immunology; Transplantation, Homologous / methods
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Mesenchymal Stem Cell Therapy: Clinical Progress and Opportunities for Advancement

Current Pathobiology Reports, 3(1), 1โ€“7.

By: J. Cassanoโ€‰*, L. Schnabel n, A. Betancourt*, D. Antczak* & L. Fortierโ€‰*

co-author countries: India ๐Ÿ‡ฎ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Source: Crossref
Added: February 24, 2020

2014 journal article

Equine bone marrow-derived mesenchymal stromal cells are heterogeneous in MHC class II expression and capable of inciting an immune response in vitro

STEM CELL RESEARCH & THERAPY, 5.

By: L. Schnabel n, L. Pezzaniteโ€‰*, D. Antczak*, M. Felippe* & L. Fortierโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Cells, Cultured; Genes, MHC Class II / genetics; Genes, MHC Class II / immunology; Horses; Immunophenotyping; Interferon-gamma / pharmacology; Leukocytes / immunology; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / drug effects; Mesenchymal Stem Cells / immunology
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Induced pluripotent stem cells have similar immunogenic and more potent immunomodulatory properties compared with bone marrow-derived stromal cells in vitro

REGENERATIVE MEDICINE, 9(5), 621โ€“635.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: allogeneic stem cell therapy; immunogenicity; immunomodulatory; induced pluripotent stem cell; mesenchymal stromal cell; transplantation medicine
MeSH headings : Animals; Cell Culture Techniques; Cell Differentiation; Cytokines / metabolism; Female; Immunomodulation; Induced Pluripotent Stem Cells / immunology; Male; Mesenchymal Stem Cells / immunology; Mice; Mice, Inbred C57BL
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Therapeutic use of stem cells in horses: Which type, how, and when?

The Veterinary Journal, 197(3), 570โ€“577.

By: L. Schnabel*, L. Fortierโ€‰*, C. Wayne McIlwraithโ€‰* & K. Nobert

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Stem cells; Equine musculoskeletal disorders; Tendonitis; Osteoarthritis; FDA
MeSH headings : Animals; Horse Diseases / therapy; Horses; Stem Cell Transplantation / veterinary
Source: Crossref
Added: February 24, 2020

2012 journal article

Cell- and gene-based approaches to tendon regeneration

Journal of Shoulder and Elbow Surgery, 21(2), 278โ€“294.

By: A. Nixon, A. Watts & L. Schnabel*

author keywords: Tendon; rotator cuff; shoulder; MSC; stem cells; gene therapy; regeneration
MeSH headings : Animals; Forecasting; Genetic Therapy / methods; Genetic Therapy / trends; Humans; Mesenchymal Stem Cell Transplantation / methods; Mesenchymal Stem Cell Transplantation / trends; Recovery of Function; Regeneration / physiology; Rotator Cuff Injuries; Tendon Injuries / therapy; Tendons / physiology; Tensile Strength; Treatment Outcome; Wound Healing / physiology
Source: Crossref
Added: February 24, 2020

2009 journal article

Mesenchymal stem cells and insulin-like growth factor-I gene-enhanced mesenchymal stem cells improve structural aspects of healing in equine flexor digitorum superficialis tendons

Journal of Orthopaedic Research, 27(10), 1392โ€“1398.

By: L. Schnabel*, M. Lynchโ€‰*, M. van der Meulenโ€‰*, A. Yeager*, M. Kornatowski* & A. Nixon*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: mesenchymal stem cells; IGF-I; gene therapy; tendinitis; in vivo
MeSH headings : ADAM Proteins / metabolism; ADAMTS4 Protein; Animals; Biomechanical Phenomena; Cell- and Tissue-Based Therapy / methods; Cell- and Tissue-Based Therapy / veterinary; Collagen Type I / metabolism; Collagen Type III / metabolism; Extracellular Matrix Proteins / metabolism; Female; Genetic Therapy / methods; Genetic Therapy / veterinary; Glycoproteins / metabolism; Horse Diseases / metabolism; Horse Diseases / pathology; Horse Diseases / therapy; Horses; Insulin-Like Growth Factor I / genetics; Insulin-Like Growth Factor I / metabolism; Male; Matrilin Proteins; Matrix Metalloproteinase 13 / metabolism; Matrix Metalloproteinase 3 / metabolism; Mesenchymal Stem Cell Transplantation / methods; Mesenchymal Stem Cell Transplantation / veterinary; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / metabolism; Procollagen N-Endopeptidase / metabolism; Tendinopathy / metabolism; Tendinopathy / therapy; Tendinopathy / veterinary; Tendons / diagnostic imaging; Tendons / metabolism; Tendons / pathology; Ultrasonography
Source: Crossref
Added: December 29, 2020

2007 journal article

Platelet rich plasma (PRP) enhances anabolic gene expression patterns in flexor digitorum superficialis tendons

Journal of Orthopaedic Research, 25(2), 230โ€“240.

By: L. Schnabel*, H. Mohammed*, B. Millerโ€‰*, W. McDermott*, M. Jacobson*, K. Santangeloโ€‰*, L. Fortierโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: platelet rich plasma (PRP); tendonitis; collagen; cartilage oligomeric matrix protein (COMP); matrix metalloproteinase (MMP)
MeSH headings : Animals; Becaplermin; Collagen / genetics; Collagen / metabolism; DNA / genetics; DNA / metabolism; Dose-Response Relationship, Drug; Extracellular Matrix Proteins / genetics; Extracellular Matrix Proteins / metabolism; Gene Expression Regulation / physiology; Glycoproteins / genetics; Glycoproteins / metabolism; Horses; Insulin-Like Growth Factor I / genetics; Insulin-Like Growth Factor I / metabolism; Matrilin Proteins; Metabolism / genetics; Metabolism / physiology; Platelet-Derived Growth Factor / genetics; Platelet-Derived Growth Factor / metabolism; Platelet-Rich Plasma / physiology; Proto-Oncogene Proteins c-sis; RNA, Messenger / genetics; RNA, Messenger / metabolism; Tendinopathy / drug therapy; Tendons / metabolism; Tissue Culture Techniques; Transforming Growth Factor beta1 / genetics; Transforming Growth Factor beta1 / metabolism
Source: Crossref
Added: February 24, 2020