Linlin Wang

2023 journal article

Comparison of Aptamer Signaling Mechanisms Reveals Disparities in Sensor Response and Strategies to Eliminate False Signals


By: O. Alkhamis n, J. Canoura n, C. Willis n, L. Wang n, J. Perry n & Y. Xiao n

MeSH headings : Aptamers, Nucleotide / chemistry; DNA; DNA, Complementary; Sensitivity and Specificity; SELEX Aptamer Technique / methods; Biosensing Techniques / methods
TL;DR: This work has developed a series of sensors using aptamers for the small-molecule drugs flunixin, fentanyl, and furanyl fentanyl and compares their performance, focusing on their specificity, and demonstrates strategies for improving the sensitivity and specificity of aptamer sensors with the development of a "hybrid beacon". (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: July 19, 2023

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