Li Zhang

Works (4)

Updated: July 5th, 2023 15:55

2009 article

Association Test for X-Linked QTL in Family-Based Designs

Zhang, L., Martin, E. R., Morris, R. W., & Li, Y.-J. (2009, April 1). The American Journal of Human Genetics.

By: L. Zhang n, E. Martin *, R. Morris * & Y. Li *

MeSH headings : Age of Onset; Algorithms; Female; Gene Dosage; Genes, X-Linked; Genetic Techniques; Genotype; Haplotypes; Humans; Likelihood Functions; Male; Models, Genetic; Monoamine Oxidase / genetics; Nuclear Family; Parkinson Disease / enzymology; Parkinson Disease / genetics; Phenotype; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Software; X Chromosome Inactivation
topics (OpenAlex): Genetic Mapping and Diversity in Plants and Animals; Genetic and phenotypic traits in livestock; Genomics and Chromatin Dynamics
TL;DR: A family-based association test for quantitative traits, named XQTL, which uses X-linked markers in a nuclear family design, and can perform allelic and two-locus haplotypic association tests and can provide estimates of additive genetic effects and variance components. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

FMR1 CGG repeat length predicts motor dysfunction in premutation carriers

Neurology (Minneapolis, Minn.), 70(16), 1397–1402.

By: M. Leehey, E. Berry-Kravis, C. Goetz, L. Zhang, D. Hall, L. Li, C. Rice, R. Lara ...

Source: NC State University Libraries
Added: August 6, 2018

2008 article

X‐LRT: a likelihood approach to estimate genetic risks and test association with X‐linked markers using a case‐parents design

Zhang, L., Martin, E. R., Chung, R. H., Li, Y. J., & Morris, R. W. (2008, February 15). Genetic Epidemiology.

By: L. Zhang n, E. Martin*, R. Chung*, Y. Li * & R. Morris *

author keywords: sex linked; maximum-likelihood estimation; confidence interval; hypothesis test; family-based design
MeSH headings : Algorithms; Biometry; Computer Simulation; Confidence Intervals; Epidemiologic Methods; Female; Genes, X-Linked; Genetic Diseases, X-Linked / epidemiology; Genetic Diseases, X-Linked / genetics; Genetic Markers; Haplotypes; Humans; Likelihood Functions; Male; Models, Genetic; Monoamine Oxidase / genetics; Parents; Parkinson Disease / enzymology; Parkinson Disease / genetics; Penetrance; Risk Factors; Siblings
topics (OpenAlex): Genetic Associations and Epidemiology; T-cell and Retrovirus Studies; Nuclear Receptors and Signaling
TL;DR: A likelihood approach to estimate disease‐related marker relative risks and test genotype association using a case‐parents design and shows how efficiency with missing parental information can be improved with additional sibling genotype information. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2006 article

X-APL: An Improved Family-Based Test of Association in the Presence of Linkage for the X Chromosome

Chung, R.-H., Morris, R. W., Zhang, L., Li, Y.-J., & Martin, E. R. (2006, December 12). The American Journal of Human Genetics.

By: R. Chung n, R. Morris, L. Zhang n, Y. Li  n & E. Martin  n

MeSH headings : Chromosomes, Human, X / genetics; Family; Female; Genetic Diseases, X-Linked / genetics; Genetic Markers; Humans; Linkage Disequilibrium; Male; Monoamine Oxidase / genetics; Parkinson Disease / genetics; Pedigree; Siblings
topics (OpenAlex): Genetic Associations and Epidemiology; Genetics and Neurodevelopmental Disorders; Nuclear Receptors and Signaling
TL;DR: A novel family-based test of association, X-APL, a modification of the test for association in the presence of linkage (APL) test that can use singleton or multiplex families and properly infers missing parental genotypes in linkage regions by considering identity-by-descent parameters for affected siblings. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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