Works (130)

Updated: March 3rd, 2026 21:07

2026 article

Intramedullary Threaded Nail Versus Dorsal Plate and Screw Fixation of Comminuted Metacarpal Shaft Fractures: A Cadaveric Biomechanical Study

Allen, A. D., Jeffs, A. D., Zhang, Y., Himmelberg, S. M., Zaidi, Z. S., Adams, N. C., … Draeger, R. W. (2026, January 12). Journal of Hand Surgery Global Online.

By: A. Allen*, A. Jeffs*, Y. Zhang n, S. Himmelberg*, Z. Zaidi*, N. Adams*, B. Lauck*, M. Fisher n, J. Patterson*, R. Draeger*

topics (OpenAlex): Orthopedic Surgery and Rehabilitation; Foot and Ankle Surgery; Elbow and Forearm Trauma Treatment; Peripheral Nerve Disorders
Source: NC State University Libraries
Added: January 29, 2026

2025 conference paper

A Larger ACL Graft Provides Better Initial Joint Stability and Graft Function in an Early Adolescent Porcine Model

Annual Meeting of the Orthopaedic Research Society. Poster presented at the Annual Meeting of the Orthopaedic Research Society, Phoenix, AZ.

By: Y. Zhang, K. Gurbuz, J. Chavez-Arellano, J. Spang & M. Fisher

Source: NC State University Libraries
Added: November 15, 2025

2025 article

Age-Related Increases in Graft Tendon Size and Stiffness During Skeletal Growth Enhance Anterior Cruciate Ligament Graft Function and Joint Stability in an Early Adolescent Porcine Model

Zhang, Y., Gurbuz, K., Chavez-Arellano, J., Opperman, L., Spang, J. T., & Fisher, M. B. (2025, December 12). Journal of Biomechanical Engineering, Vol. 12.

MeSH headings : Animals; Swine; Tendons / transplantation; Tendons / physiology; Anterior Cruciate Ligament / physiology; Anterior Cruciate Ligament / surgery; Biomechanical Phenomena; Mechanical Phenomena; Aging / physiology; Anterior Cruciate Ligament Reconstruction
topics (OpenAlex): Knee injuries and reconstruction techniques; Tendon Structure and Treatment; Total Knee Arthroplasty Outcomes
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: December 13, 2025

2025 conference paper

Impact of Sex Hormones on Size, Organization, and Mechanics of the Adolescent Porcine Anterior Cruciate Ligament and Potential Mechanisms Through Estrogen Receptors

2025 ASME SB3C Summer Bioengineering Conference. Presented at the 2025 ASME SB3C Summer Bioengineering Conference, Santa Ana Pueblo, NM.

By: J. Thompson & M. Fisher

Source: NC State University Libraries
Added: November 15, 2025

2025 conference paper

Intramedullary Threaded Nail Versus Plate And Screw Fixation Of Comminuted Metacarpal Shaft Fractures: A Biomechanical Study

80th American Society for Surgery of the Hand Annual Meeting. Poster presented at the 80th American Society for Surgery of the Hand Annual Meeting, Vancouver, Canada.

By: A. Allen, A. Jeffs, Y. Zhang, Z. Zaidi, N. Adams, B. Lauck, J. Patterson, R. Draeger, M. Fisher

Source: NC State University Libraries
Added: November 15, 2025

2025 journal article

Noninvasive Fibrin Targeting Colloid‐Mediated Intra‐Articular Repair

Journal of Biomedical Materials Research Part A, 113(4).

By: G. Scull n, J. Thompson n, M. Osareh n, Y. Rey n, A. Aligwekwe n, S. Finkelstein n, L. Schnabel n, M. Fisher n, A. Brown n

author keywords: ACL injury; biomaterials; clotting; fibrin; microgels; synovial fluid; synthetic platelets
MeSH headings : Fibrin / chemistry; Fibrin / metabolism; Synovial Fluid / metabolism; Tissue Scaffolds / chemistry; Colloids / chemistry; Humans; Animals; Wound Healing / drug effects; Viscosity
topics (OpenAlex): Peripheral Artery Disease Management; Vascular Procedures and Complications; Reconstructive Surgery and Microvascular Techniques
Sources: Web Of Science, Crossref, NC State University Libraries
Added: April 7, 2025

2025 journal article

Physeal-sparing anterior cruciate ligament reconstruction in an early adolescent porcine model provides better anterior stability but similar tissue function compared to a juvenile porcine model

Clinical Biomechanics, 130, 106667.

By: K. Gurbuz*, Y. Zhang n, L. Opperman n, J. Spang* & M. Fisher n

author keywords: Knee; ACL; Pediatrics; Physeal-sparing; Robotic testing
topics (OpenAlex): Knee injuries and reconstruction techniques; Tendon Structure and Treatment; Sports injuries and prevention
Sources: Web Of Science, NC State University Libraries, Crossref
Added: October 13, 2025

2025 journal article

Physeal‐sparing anterior cruciate ligament reconstruction provides better initial joint biomechanics than complete transphyseal reconstruction in an early adolescent porcine model

Journal of Experimental Orthopaedics, 12(4).

By: Y. Zhang n, K. Gurbuz n, L. Opperman n, J. Spang* & M. Fisher n

author keywords: ACL reconstruction; biomechanics; knee; paediatrics; robotics
topics (OpenAlex): Knee injuries and reconstruction techniques; Total Knee Arthroplasty Outcomes; Tendon Structure and Treatment
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: October 7, 2025

2025 conference paper

Regional Changes to the Knee Meniscus Occur Earlier Than Whole Tissue Changes After Anterior Cruciate Ligament Injury in a Juvenile Porcine Model

2025 ASME SB3C Summer Bioengineering Conference. Presented at the 2025 ASME SB3C Summer Bioengineering Conference, Santa Ana Pueblo, NM.

By: M. Easson, J. Thompson, D. Howe, R. Morris, E. Keeley, L. Schnabel, J. Spang, M. Fisher

Source: NC State University Libraries
Added: November 15, 2025

2025 conference paper

Regional Size and Biochemical Changes in the Meniscus after ACL Injury in a Skeletally Immature Porcine Model

Annual Meeting of the Orthopaedic Research Society. Presented at the Annual Meeting of the Orthopaedic Research Society, Phoenix, AZ.

By: M. Easson, R. Morris, E. Keeley, L. Schnabel, J. Spang & M. Fisher

Source: NC State University Libraries
Added: November 15, 2025

2025 journal article

Soaking in Povidone-Iodine, Chlorhexidine, Teicoplanin, Vancomycin, and Saline Solution Differentially Alters Porcine Flexor Tendon Size and Biomechanical Properties

Arthroscopy, Sports Medicine, and Rehabilitation, 7(4), 101168.

By: K. Gurbuz n, Y. Zhang n, L. Opperman n & M. Fisher n

topics (OpenAlex): Orthopedic Surgery and Rehabilitation; Tendon Structure and Treatment; Orthopedic Infections and Treatments
Sources: ORCID, Crossref, NC State University Libraries
Added: June 12, 2025

2025 conference paper

The Anterior Cruciate Ligament in Pre-pubescent Pigs has Greater Collagen Gene Expression and Estrogen Receptor Protein Expression than n Post-pubescent Pigs

Annual Meeting of the Orthopaedic Research Society. Poster presented at the Annual Meeting of the Orthopaedic Research Society, Phoenix, AZ.

By: J. Thompson & M. Fisher

Source: NC State University Libraries
Added: November 15, 2025

2024 journal article

3D melt blowing of Elastollan thermoplastic polyurethane for tissue engineering applications: A pilot study

Manufacturing Letters, 41, 357–363.

By: A. Pawar n, B. Anderson n, B. Pourdeyhimi n, A. McNulty*, M. Fisher n & R. Shirwaiker n

author keywords: tissue engineering; nonwoven; meltblowing; musculoskeletal; scaffolds; thermoplastic polyurethane; Elastollan
topics (OpenAlex): Electrospun Nanofibers in Biomedical Applications; Bone Tissue Engineering Materials; Additive Manufacturing and 3D Printing Technologies
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: January 27, 2025

2024 journal article

A Systems Approach to Biomechanics, Mechanobiology, and Biotransport

Journal of Biomechanical Engineering, 146(4).

MeSH headings : Humans; Biomechanical Phenomena; Bioengineering; Biophysics; Systems Analysis
topics (OpenAlex): Cellular Mechanics and Interactions; 3D Printing in Biomedical Research; Muscle Physiology and Disorders
Sources: Web Of Science, NC State University Libraries, Crossref
Added: April 1, 2024

2024 conference paper

Changes In Tibial Plateau Geometry With Skeletal Maturation In A Porcine Model

Annual Meeting of the Orthopaedic Research Society. Poster presented at the Annual Meeting of the Orthopaedic Research Society, Long Beach, CA.

By: G. Ahrendt, L. Mattar, T. Chen, M. Fisher, V. Musahl & R. Debski

Event: Annual Meeting of the Orthopaedic Research Society at Long Beach, CA on February 2-6, 2024

Source: NC State University Libraries
Added: November 15, 2025

2024 conference paper

Complete Transphyseal, Partial Transphyseal, And Physeal-Sparing ACL Reconstruction Provides Similar Initial Joint Stability And Function In Early Juvenile Porcine Model

Annual Meeting of the Orthopaedic Research Society. Poster presented at the Annual Meeting of the Orthopaedic Research Society, Long Beach, CA.

By: Y. Zhang, K. Gurbuz, J. Spang & M. Fisher

Event: Annual Meeting of the Orthopaedic Research Society at Long Beach, CA on February 2-6, 2024

Source: NC State University Libraries
Added: November 15, 2025

2024 journal article

Controlled Stiffness of Direct-Write, Near-Field Electrospun Gelatin Fibers Generates Differences in Tenocyte Morphology and Gene Expression

Journal of Biomechanical Engineering, 146(9).

By: Z. Davis n, D. Koch n, S. Watson n, G. Scull n, A. Brown n, L. Schnabel n, M. Fisher n

MeSH headings : Gelatin / chemistry; Animals; Horses; Tenocytes / cytology; Tenocytes / metabolism; Tissue Scaffolds / chemistry; Mechanical Phenomena; Gene Expression Regulation; Cell Shape; Biomechanical Phenomena
topics (OpenAlex): Tendon Structure and Treatment; Sports injuries and prevention; Shoulder Injury and Treatment
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: May 17, 2024

2024 conference paper

Differential Effects Of Four Antimicrobial Agents On The Size And Biomechanics Of Tendon Grafts

Annual Meeting of the Orthopaedic Research Society. Poster presented at the Annual Meeting of the Orthopaedic Research Society, Long Beach, CA.

By: K. Gurbuz, Y. Zhang & M. Fisher

Event: Annual Meeting of the Orthopaedic Research Society at Long Beach, CA on February 2-6, 2024

Source: NC State University Libraries
Added: November 15, 2025

2024 journal article

Early degenerative changes are different between partial and complete anterior cruciate ligament injury and associate with joint instability in a skeletally immature porcine model

Osteoarthritis and Cartilage, 33(2), 302–312.

By: D. Howe*, J. Thompson*, S. Teeter n, M. Easson*, O. Barlow n, E. Griffith n, L. Schnabel*, J. Spang*, M. Fisher*

author keywords: Anterior cruciate ligament; Osteoarthritis; Biomechanics; Pediatrics; Orthopedics
MeSH headings : Animals; Joint Instability / physiopathology; Joint Instability / pathology; Anterior Cruciate Ligament Injuries / complications; Anterior Cruciate Ligament Injuries / pathology; Swine; Disease Models, Animal; Magnetic Resonance Imaging; Cartilage, Articular / pathology; Cartilage, Articular / diagnostic imaging; Cartilage, Articular / injuries; Biomechanical Phenomena; Female; Menisci, Tibial / surgery; Menisci, Tibial / pathology
topics (OpenAlex): Knee injuries and reconstruction techniques; Total Knee Arthroplasty Outcomes; Orthopedic Surgery and Rehabilitation
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: February 10, 2025

2024 conference paper

Estrogen Receptor Expression is Greater than Progesterone Receptor Expression in the Porcine Anterior Cruciate Ligament and Varies Across Age and Animal

2024 Summer Biomechanics, Bioengineering and Biotransport Conference. Presented at the 2024 Summer Biomechanics, Bioengineering and Biotransport Conference, Lake Geneva, WI.

By: J. Thompson & M. Fisher

Event: 2024 Summer Biomechanics, Bioengineering and Biotransport Conference at Lake Geneva, WI on June 11-14, 2024

Source: NC State University Libraries
Added: November 15, 2025

2024 conference paper

Injectable Synthetic Platelet-Based Therapy Enhances Clot Formation in Synovial Fluid Joint Injury Model

Society for Biomaterials. Presented at the Society for Biomaterials, Northeastern University, Boston MA.

By: M. Osareh, O. Obasuyi, G. Scull, J. Thompson, A. Brown & M. Fisher

Event: Society for Biomaterials at Northeastern University, Boston MA on September 19-20, 2024

Source: NC State University Libraries
Added: November 15, 2025

2024 conference paper

Injectable Synthetic Platelet-Based Therapy Enhances Clot Formation in Synovial Fluid Joint Injury Model

2024 Summer Biomechanics, Bioengineering and Biotransport Conference. Presented at the 2024 Summer Biomechanics, Bioengineering and Biotransport Conference, Lake Geneva, WI.

By: M. Osareh, G. Scull, J. Thompson, A. Brown & M. Fisher

Event: 2024 Summer Biomechanics, Bioengineering and Biotransport Conference at Lake Geneva, WI on June 11-14, 2024

Source: NC State University Libraries
Added: November 15, 2025

2024 conference paper

Injectable Synthetic Platelet-Based Therapy Enhances Clot Formation in Synovial Fluid Joint Injury Model

Society for Biomaterials, North Carolina State University Chapter. Presented at the Society for Biomaterials, North Carolina State University Chapter, Raleigh NC.

By: M. Osareh, G. Scull, J. Thompson, A. Brown & M. Fisher

Event: Society for Biomaterials, North Carolina State University Chapter at Raleigh NC

Source: NC State University Libraries
Added: November 15, 2025

2024 conference paper

Meniscus Cellular Responses Are Similar On Different Aged Meniscus-derived Matrix Scaffolds

Annual Meeting of the Orthopaedic Research Society. Poster presented at the Annual Meeting of the Orthopaedic Research Society, Long Beach, CA.

By: S. Firoozi, R. Shirwaiker, M. Fisher & A. McNulty

Event: Annual Meeting of the Orthopaedic Research Society at Long Beach, CA on February 2-6, 2024

Source: NC State University Libraries
Added: November 15, 2025

2024 conference paper

Meniscus Remodeling After ACL Injury Is Region-Specific In A Skeletally Immature Porcine Model

Annual Meeting of the Orthopaedic Research Society. Poster presented at the Annual Meeting of the Orthopaedic Research Society, Long Beach, CA.

By: M. Easson, J. Thompson, R. Morris, E. Keeley, L. Schnabel, J. Spang, M. Fisher

Event: Annual Meeting of the Orthopaedic Research Society at Long Beach, CA on February 2-6, 2024

Source: NC State University Libraries
Added: November 15, 2025

2024 conference paper

Meniscus Remodeling after ACL Injury is Region-Specific in a Skeletally Immature Porcine Model

Biomedical Engineering Society Annual Meeting. Presented at the Biomedical Engineering Society Annual Meeting, Baltimore, MD.

By: M. Easson, J. Thompson, R. Morris, E. Keeley, L. Schnabel, J. Spang, M. Fisher

Event: Biomedical Engineering Society Annual Meeting at Baltimore, MD on October 23-26, 2024

Source: NC State University Libraries
Added: November 15, 2025

2024 conference paper

Physeal-Sparing ACL Reconstruction Provides Better Initial Joint Stability and Function than Complete Transphyseal ACL Reconstruction in an Early Adolescent Porcine Model

2024 Summer Biomechanics, Bioengineering and Biotransport Conference. Presented at the 2024 Summer Biomechanics, Bioengineering and Biotransport Conference, Lake Geneva, WI.

By: Y. Zhang, K. Gurbuz, J. Spang & M. Fisher

Event: 2024 Summer Biomechanics, Bioengineering and Biotransport Conference at Lake Geneva, WI on June 11-14, 2024

Source: NC State University Libraries
Added: November 15, 2025

2024 conference paper

Regional Mechanical Properties on the Macroscale and Microscale are not Associated for the Equine Superficial Digital Flexor Tendon

2024 Summer Biomechanics, Bioengineering and Biotransport Conference. Poster presented at the 2024 Summer Biomechanics, Bioengineering and Biotransport Conference, Lake Geneva, WI.

By: S. Watson, Z. Davis, S. Connard, L. Schnabel & M. Fisher

Event: 2024 Summer Biomechanics, Bioengineering and Biotransport Conference at Lake Geneva, WI on June 11-14, 2024

Source: NC State University Libraries
Added: November 15, 2025

2024 conference paper

Selective Bundle ACL Reconstruction Does Not Initially Restore the Normal ACL Force Distribution in an Adolescent Porcine Model: Implications for Treatment of Partial ACL Injuries

Biomedical Engineering Society Annual Meeting. Presented at the Biomedical Engineering Society Annual Meeting, Baltimore, MD.

By: Y. Zhang, K. Gurbuz, J. Spang & M. Fisher

Event: Biomedical Engineering Society Annual Meeting at Baltimore, MD on October 23-26, 2024

Source: NC State University Libraries
Added: November 15, 2025

2024 conference paper

Selective Bundle ACL Reconstruction Does Not Initially Restore the Normal ACL Force Distribution in an Adolescent Porcine Model: Implications for Treatment of Partial ACL Injuries

2024 Summer Biomechanics, Bioengineering and Biotransport Conference. Poster presented at the 2024 Summer Biomechanics, Bioengineering and Biotransport Conference, Lake Geneva, WI.

By: Y. Zhang, K. Gurbuz, J. Spang & M. Fisher

Event: 2024 Summer Biomechanics, Bioengineering and Biotransport Conference at Lake Geneva, WI on June 11-14, 2024

Source: NC State University Libraries
Added: November 15, 2025

2024 conference paper

The Pediatric Anterior Cruciate Ligament: Role of Sex and Age, Impact of Injury, and Other Insights from a Preclinical Model

Orthopaedic Research Society Annual Meeting. Presented at the Orthopaedic Research Society Annual Meeting, Long Beach, CA.

By: M. Fisher

Event: Orthopaedic Research Society Annual Meeting at Long Beach, CA on February 2-6, 2024

Source: NC State University Libraries
Added: November 15, 2025

2023 conference paper

A multi-enzyme protocol provides greater amino acid sequence coverage of collagen and elastin in extracellular matrices

71st ASMS Conference on Mass Spectrometry and Allied Topics. Poster presented at the 71st ASMS Conference on Mass Spectrometry and Allied Topics, Houston, TX.

By: L. Collins, T. Williams, A. Biehl, A. Martins, Z. Davis, D. Sze, C. Mora-Navarro, M. Fisher, D. Freytes

Event: 71st ASMS Conference on Mass Spectrometry and Allied Topics at Houston, TX on June 4-8, 2023

Source: NC State University Libraries
Added: November 15, 2025

2023 conference paper

ACL Injury And Joint Instability Leads To Meniscal Hypertrophy In A Skeletally Immature Porcine Model

2023 Summer Biomechanics, Bioengineering and Biotransport Conference. Presented at the 2023 Summer Biomechanics, Bioengineering and Biotransport Conference, Vail, CO.

By: J. Thompson, M. Easson, D. Howe, L. Schnabel, J. Spang, B. Pietrosimone, M. Fisher

Event: 2023 Summer Biomechanics, Bioengineering and Biotransport Conference at Vail, CO on June 4-8, 2023

Source: NC State University Libraries
Added: November 15, 2025

2023 conference paper

Crosslinking Method of Aligned Direct-Write Near-Field Electrospun Gelatin Fibers Alters Stiffness, Cytocompatibility, and Tenocyte Morphology

Annual Meeting of the Orthopaedic Research Society. Poster presented at the Annual Meeting of the Orthopaedic Research Society, Dallas, TX.

By: Z. Davis, G. Scull, D. Koch, L. Schnabel, A. Brown & M. Fisher

Event: Annual Meeting of the Orthopaedic Research Society at Dallas, TX on February 10-14, 2023

Source: NC State University Libraries
Added: November 21, 2025

2023 conference paper

Enhanced Clotting in Synovial Fluid with Colloidal-Composite Gels for Partial Anterior Cruciate Ligament Tears

Annual Meeting of the Orthopaedic Research Society. Poster presented at the Annual Meeting of the Orthopaedic Research Society, Dallas, TX.

By: J. Thompson, G. Scull, L. Schnabel, M. Fisher & A. Brown

Event: Annual Meeting of the Orthopaedic Research Society at Dallas, TX on February 10-14, 2023

Source: NC State University Libraries
Added: November 15, 2025

2023 conference paper

M.B.* Age-Specific Size and Biomechanical Properties of Deep Digital Flexor Tendon During Skeletal Growth in a Porcine Model: Implications for ACL Reconstruction

Annual Meeting of the Orthopaedic Research Society. Poster presented at the Annual Meeting of the Orthopaedic Research Society, Dallas, TX.

By: Y. Zhang & J. Spang

Event: Annual Meeting of the Orthopaedic Research Society at Dallas, TX on February 10-14, 2023

Source: NC State University Libraries
Added: November 21, 2025

2023 conference paper

M.B.* Degenerative Changes Are Associated with Joint Instability after Partial and Complete ACL Injury in a Skeletally Immature Porcine Model

Annual Meeting of the Orthopaedic Research Society. Presented at the Annual Meeting of the Orthopaedic Research Society, Dallas, TX.

By: D. Howe, J. Thompson, L. Schnabel, J. Spang & M. Fisher

Event: Annual Meeting of the Orthopaedic Research Society at Dallas, TX on February 10-14, 2023

Source: NC State University Libraries
Added: November 15, 2025

2023 conference paper

Mechanical Properties of the Equine Superficial Digital Flexor Tendon Are Not Strongly Associated Across Macroscopic and Microscopic Scales

Biomedical Engineering Society Annual Meeting. Presented at the Biomedical Engineering Society Annual Meeting, Seattle, WA.

By: S. Watson, Z. Davis, D. Koch, L. Schnabel & M. Fisher

Event: Biomedical Engineering Society Annual Meeting at Seattle, WA on October 11-14, 2023

Source: NC State University Libraries
Added: November 15, 2025

2023 journal article

Neo-Natal Castration Leads to Subtle Differences in Porcine Anterior Cruciate Ligament Morphology and Function in Adolescence

Journal of Biomechanical Engineering, 146(1).

MeSH headings : Humans; Adolescent; Male; Animals; Swine; Female; Anterior Cruciate Ligament / physiology; Anterior Cruciate Ligament / surgery; Anterior Cruciate Ligament Injuries; Knee Injuries; Castration; Testosterone; Knee Joint / physiology
topics (OpenAlex): Knee injuries and reconstruction techniques; Sports injuries and prevention; Cardiovascular Effects of Exercise
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: October 23, 2025

2023 article

Neo-natal castration leads to subtle differences in porcine anterior cruciate ligament morphology and function in adolescence

Thompson, J. D., Howe, D., Griffith, E. H., Schnabel, L. V., & Fisher, M. B. (2023, January 25).

By: J. Thompson n, D. Howe n, E. Griffith n, L. Schnabel & M. Fisher n

topics (OpenAlex): Knee injuries and reconstruction techniques; Sports Performance and Training; Adhesion, Friction, and Surface Interactions
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: December 13, 2024

2023 conference paper

Optimizing Decellularization of Meniscus Tissue for Meniscus Tissue Engineering Applications

Annual Meeting of the Orthopaedic Research Society. Poster presented at the Annual Meeting of the Orthopaedic Research Society, Dallas, TX.

By: S. Firoozi, R. Shirwaiker, M. Fisher & A. McNulty

Event: Annual Meeting of the Orthopaedic Research Society at Dallas, TX on February 10-14, 2023

Source: NC State University Libraries
Added: November 21, 2025

2023 journal article

Preclinical tendon and ligament models: Beyond the 3Rs (replacement, reduction, and refinement) to 5W1H (why, who, what, where, when, how)

Journal of Orthopaedic Research, 41(10), 2133–2162.

MeSH headings : Animals; Tendons; Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament / surgery; Tendon Injuries; Rotator Cuff Injuries
topics (OpenAlex): Tendon Structure and Treatment; Shoulder Injury and Treatment; Knee injuries and reconstruction techniques
Sources: ORCID, Crossref, NC State University Libraries
Added: February 8, 2025

2023 conference paper

Stiffness Of Direct-Write Near-Field Electrospun Gelatin Fibers Generates Differences In Tenocyte Gene Expression

2023 Summer Biomechanics, Bioengineering and Biotransport Conference. Presented at the 2023 Summer Biomechanics, Bioengineering and Biotransport Conference, Vail, CO.

By: Z. Davis, D. Koch, G. Scull, A. Brown, L. Schnabel & M. Fisher

Event: 2023 Summer Biomechanics, Bioengineering and Biotransport Conference at Vail, CO on June 4-8, 2023

Source: NC State University Libraries
Added: November 15, 2025

2023 journal article

Tendon Extracellular Matrix Promotes Myotendinous Junction Protein Expression in Engineered Muscle Tissue under Both Static and Mechanically Stimulated Culture Conditions

Journal of Tissue Engineering and Regenerative Medicine, 2023, 1–13.

By: L. Gaffney n, M. Fisher n & D. Freytes n

Ed(s): C. Kuo

MeSH headings : Animals; Tendons / metabolism; Tissue Engineering / methods; Extracellular Matrix / metabolism; Mice; Cell Line; Hydrogels / chemistry; Bioreactors; Myoblasts / cytology; Myoblasts / metabolism; Paxillin / metabolism; Myotendinous Junction
topics (OpenAlex): Tendon Structure and Treatment; Tissue Engineering and Regenerative Medicine; Knee injuries and reconstruction techniques
TL;DR: This research combined a relevant microenvironment to study muscle and tendon interactions with a novel bioreactor to apply mechanical strain, an important regulator of the formation and maintenance of the native MTJ. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: September 18, 2023

2023 conference paper

Using Team Science to Study Musculoskeletal Tissue Engineering

Comparative Medicine Institute Annual Summit. Presented at the Comparative Medicine Institute Annual Summit, NC State University, Raleigh, NC.

By: M. Fisher

Event: Comparative Medicine Institute Annual Summit at NC State University, Raleigh, NC on August 17, 2023

Source: NC State University Libraries
Added: November 21, 2025

2022 conference paper

ACL During Growth and Development: Basic Science and Implications for Prevention and Treatment of Injuries

ACL Research Retreat IX. Keynote presented at the ACL Research Retreat IX, High Point, NC.

By: M. Fisher

Event: ACL Research Retreat IX at High Point, NC on March 17-19, 2022

Source: NC State University Libraries
Added: November 21, 2025

2022 conference paper

ACL Injury Impacts Long-Term Knee Function And Meniscus Remodeling In A Skeletally Immature Porcine Model

Annual Meeting of the Orthopaedic Research Society. Presented at the Annual Meeting of the Orthopaedic Research Society, Tampa, FL.

By: D. Howe, J. Thompson, A. Bautista, L. Schnabel, J. Spang, B. Pietrosimone, M. Fisher

Event: Annual Meeting of the Orthopaedic Research Society at Tampa, FL on February 4-8, 2022

Source: NC State University Libraries
Added: November 21, 2025

2022 conference paper

Changes in Serum, But Not Synovial Fluid, Levels of Inflammatory Biomarker MCP-1 are Correlated with Cartilage T2* Relaxation Times after ACL Injury in a Juvenile Porcine Model

Annual Meeting of the Orthopaedic Research Society. Poster presented at the Annual Meeting of the Orthopaedic Research Society, Tampa, FL.

By: D. Howe, J. Thompson, H. Willcockson, L. Schnabel, L. Longobardi, J. Spang, B. Pietrosimone, M. Fisher

Event: Annual Meeting of the Orthopaedic Research Society at Tampa, FL on February 4-8, 2022

Source: NC State University Libraries
Added: November 21, 2025

2022 conference paper

Characterization of 3D Porosity and Biomechanical Properties of 3D-Melt Blown Scaffolds for Tissue Engineering

IISE Annual Conference & Expo. Presented at the IISE Annual Conference & Expo.

By: K. Schuchard, A. Pawar, B. Anderson, B. Pourdeyhimi, M. Fisher & R. Shirwaiker

Event: IISE Annual Conference & Expo on May 21-25, 2022

Source: NC State University Libraries
Added: November 21, 2025

2022 article

Degenerative changes are associated with severity of anterior cruciate ligament injury within the skeletally immature joint

Howe, D., Thompson, J. D., Teeter, S. D., Easson, M., Barlow, O., Griffith, E. H., … Fisher, M. B. (2022, November 13).

By: D. Howe n, J. Thompson n, S. Teeter n, M. Easson, O. Barlow n, E. Griffith n, L. Schnabel n, J. Spang*, M. Fisher n

topics (OpenAlex): Knee injuries and reconstruction techniques; Sports injuries and prevention; Cardiovascular Effects of Exercise
TL;DR: A skeletally immature preclinical porcine model is used to evaluate joint biomechanics and degeneration after partial (isolated anteromedial (AM) or posterolateral (PL) bundle) or complete ACL injury and indicates the importance of considering joint laxity as a factor when treating young patients, particularly those with partial ACL injuries. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: November 14, 2022

2022 journal article

Differences in Gait Biomechanics Between Adolescents and Young Adults With Anterior Cruciate Ligament Reconstruction

Journal of Athletic Training, 57(9-10), 921–928.

author keywords: knee; age; pediatric; youth
MeSH headings : Humans; Female; Young Adult; Adolescent; Adult; Biomechanical Phenomena; Case-Control Studies; Cross-Sectional Studies; Anterior Cruciate Ligament Injuries / surgery; Gait; Knee Joint / surgery; Anterior Cruciate Ligament Reconstruction / methods
topics (OpenAlex): Knee injuries and reconstruction techniques; Sports injuries and prevention; Total Knee Arthroplasty Outcomes
TL;DR: Adolescents and adults demonstrated different gait patterns post-ACLR, suggesting that age may play a role in altered gait biomechanics. (via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: March 6, 2023

2022 conference paper

Differences in Porcine ACL Morphology and Function are Minor Between Boars And Barrows at Early Adolescence

Summer Biomechanics, Bioengineering and Biotransport Conference. Presented at the Summer Biomechanics, Bioengineering and Biotransport Conference, Eastern Shore, Maryland.

By: J. Thompson, D. Howe, L. Schnabel & M. Fisher

Event: Summer Biomechanics, Bioengineering and Biotransport Conference at Eastern Shore, Maryland on June 20-23, 2022

Source: NC State University Libraries
Added: November 21, 2025

2022 conference paper

Dynamic Provisional Matrix Colloidal-Composite Scaffolds for Partial Anterior Cruciate Ligament Tears

Society for Biomaterials Annual Meeting. Presented at the Society for Biomaterials Annual Meeting.

By: G. Scull, J. Thompson, S. Nandi, L. Schnabel, M. Fisher & A. Brown

Event: Society for Biomaterials Annual Meeting on April 27-30, 2022

Source: NC State University Libraries
Added: November 21, 2025

2022 journal article

Effect of epitendinous suture augmentation to a double Krackow suture pattern for canine gastrocnemius tendon repair

American Journal of Veterinary Research, 83(7).

By: A. Downey n, D. Duffy n, Y. Chang n, M. Fisher n & G. Moore*

MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dog Diseases / surgery; Dogs; Suture Techniques / veterinary; Sutures / veterinary; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tendons / surgery; Tensile Strength
topics (OpenAlex): Tendon Structure and Treatment; Orthopedic Surgery and Rehabilitation; Shoulder Injury and Treatment
TL;DR: Augmentation of a primary DK repair with an ES significantly improved construct strength in canine GT constructs while increasing loads required to cause 1- and 3-mm gap formation, respectively. (via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: June 27, 2022

2022 journal article

Elucidating the combinatorial effect of substrate stiffness and surface viscoelasticity on cellular phenotype

Journal of Biomedical Materials Research Part A, 110(6), 1224–1237.

By: D. Chester n, V. Lee n, P. Wagner n, M. Nordberg n, M. Fisher n & A. Brown n

author keywords: loss tangent; mechanotransduction; microgel; viscoelasticity
MeSH headings : Biocompatible Materials / chemistry; Hydrogels / chemistry; Hydrogels / pharmacology; Mechanotransduction, Cellular / physiology; Phenotype; Viscosity
topics (OpenAlex): Cellular Mechanics and Interactions; Blood properties and coagulation; 3D Printing in Biomedical Research
TL;DR: A novel composite hydrogel system capable of decoupling and individually controlling both the bulk stiffness and surface viscoelasticity of the material by combining polyacrylamide gels with microgel thin films is characterized, allowing for a greater understanding of cellular mechanotransduction mechanisms than previously possible through current model material platforms. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: February 7, 2022

2022 conference paper

Elucidating the combinatorial effect of substrate stiffness and surface viscoelasticity on cellular phenotype

Society for Biomaterials Annual Meeting. Presented at the Society for Biomaterials Annual Meeting.

By: D. Chester, V. Lee, P. Wagner, M. Nordberg, M. Fisher & A. Brown

Event: Society for Biomaterials Annual Meeting on April 27-30, 2022

Source: NC State University Libraries
Added: November 21, 2025

2022 conference paper

Exploring Nonwovens Fabrication of Elastollan Thermoplastic Polyurethane for Biomedical Applications

IISE Annual Conference & Expo. Presented at the IISE Annual Conference & Expo.

By: A. Pawar, B. Anderson, M. Fisher, B. Pourdeyhimi & R. Shirwaiker

Event: IISE Annual Conference & Expo on May 21-25, 2022

Source: NC State University Libraries
Added: November 21, 2025

2022 conference paper

Optimization of ECM/Gelatin Solution in a Near Field Electrospinning System for Engineering Tendon

Summer Biomechanics, Bioengineering and Biotransport Conference. Poster presented at the Summer Biomechanics, Bioengineering and Biotransport Conference, Eastern Shore, Maryland.

By: A. Hussain, Z. Davis & M. Fisher

Event: Summer Biomechanics, Bioengineering and Biotransport Conference at Eastern Shore, Maryland on June 20-23, 2022

Source: NC State University Libraries
Added: November 21, 2025

2022 conference paper

Optimizing Decellularization of Meniscus Tissue for Meniscus Tissue Engineering Applications

Triangle Regeneration Biology Symposium. Poster presented at the Triangle Regeneration Biology Symposium, Durham, NC.

By: S. Firoozi, R. Shirwaiker, M. Fisher & A. McNulty

Event: Triangle Regeneration Biology Symposium at Durham, NC

Source: NC State University Libraries
Added: November 21, 2025

2022 conference paper

Partial ACL Injury Location Impacts Biomechanics and Tissue Remodeling in a Skeletally Immature Porcine Model

2022 Summer Biomechanics, Bioengineering and Biotransport Conference. Presented at the 2022 Summer Biomechanics, Bioengineering and Biotransport Conference, Eastern Shore, Maryland.

By: D. Howe, J. Thompson, A. Bautista, L. Schnabel, J. Spang & M. Fisher

Event: 2022 Summer Biomechanics, Bioengineering and Biotransport Conference at Eastern Shore, Maryland on June 20-23, 2022

Source: NC State University Libraries
Added: November 21, 2025

2022 conference paper

Stance Phase Gait Biomechanics Differ Between Adolescents and Adults after ACLR

ACL Research Retreat IX. Presented at the ACL Research Retreat IX, High Point, NC.

By: C. Lisee, W. Horton, E. Bjornsen, H. Davis-Wilson, J. Blackburn, M. Fisher, B. Pietrosimone

Event: ACL Research Retreat IX at High Point, NC on March 7-9, 2022

Source: NC State University Libraries
Added: November 21, 2025

2022 journal article

Towards a standardized multi-tissue decellularization protocol for the derivation of extracellular matrix materials

Biomaterials Science, 11(2), 641–654.

MeSH headings : Tissue Engineering / methods; Proteomics; Extracellular Matrix / chemistry; Hydrogels / chemistry; Biocompatible Materials / analysis; Tissue Scaffolds
topics (OpenAlex): Tissue Engineering and Regenerative Medicine; Electrospun Nanofibers in Biomedical Applications; Bone Tissue Engineering Materials
TL;DR: The present study is the first proof-of-concept towards the development of a standardized protocol that can be used to derive multiple ECM biomaterials via a previously established automated system and showed gelation and rheological properties consistent with previous ECM hydrogels. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: January 3, 2023

2022 conference paper

Variable stiffness of direct-written gelatin fibers with crosslinking technique: Toward a tendon tissue-on-a-chip model

Society for Biomaterials Annual Meeting. Presented at the Society for Biomaterials Annual Meeting.

By: Z. Davis, G. Scull, A. Brown & M. Fisher

Event: Society for Biomaterials Annual Meeting on April 27-30, 2022

Source: NC State University Libraries
Added: November 21, 2025

2021 journal article

A Direct Comparison of Node and Element-Based Finite Element Modeling Approaches to Study Tissue Growth

Journal of Biomechanical Engineering, 144(1).

By: D. Howe n, N. Dixit n, K. Saul n & M. Fisher n

MeSH headings : Bone and Bones; Finite Element Analysis; Models, Biological
topics (OpenAlex): Cellular Mechanics and Interactions; Elasticity and Material Modeling; Bone health and osteoporosis research
TL;DR: The importance of the choice of implementation approach for modeling growth is illustrated, a framework for converting models between implementation approaches is provided, and important considerations for comparing results in prior work and developing new models of tissue growth are highlighted. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: January 3, 2022

2021 journal article

Age- and Sex-Specific Joint Biomechanics in Response to Partial and Complete Anterior Cruciate Ligament Injury in the Porcine Model

Journal of Athletic Training, 57(9-10), 978–989.

By: D. Howe n, S. Cone n, J. Piedrahita n, J. Spang* & M. Fisher n

author keywords: knee; transection studies; sex factors
MeSH headings : Male; Female; Humans; Animals; Swine; Anterior Cruciate Ligament Injuries / surgery; Anterior Cruciate Ligament / surgery; Anterior Cruciate Ligament / physiology; Biomechanical Phenomena; Joint Instability; Knee Joint; Cadaver
topics (OpenAlex): Knee injuries and reconstruction techniques; Sports injuries and prevention; Shoulder Injury and Treatment
TL;DR: Increased forces in the MCL and medial meniscus after ACL transection suggest that rehabilitation protocols may need to focus on protecting these tissues, and operative treatment should be considered in active, late adolescent patients. (via Semantic Scholar)
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3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: March 6, 2023

2021 journal article

Age‐ and sex‐specific differences in ACL and ACL bundle size during adolescent growth

Journal of Orthopaedic Research, 40(7), 1613–1620.

author keywords: ACL; bundles; growth; MRI; pediatrics
MeSH headings : Adolescent; Animals; Anterior Cruciate Ligament / diagnostic imaging; Anterior Cruciate Ligament Injuries; Child; Female; Humans; Magnetic Resonance Imaging / methods; Male; Models, Animal; Retrospective Studies
topics (OpenAlex): Knee injuries and reconstruction techniques; Sports injuries and prevention; Shoulder Injury and Treatment
TL;DR: Findings in the length and cross‐sectional area (CSA) of the ACL and its primary bundles in adolescent human subjects may point toward biomechanical changes in the adolescent human ACL. (via Semantic Scholar)
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3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: November 15, 2021

2021 journal article

Biomechanical analysis of accessory tendon graft augmentation for primary gastrocnemius tendon reconstruction in dogs

Veterinary Surgery, 50(5), 1147–1156.

By: D. Duffy n, Y. Chang n, M. Fisher n & G. Moore*

MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dog Diseases / surgery; Dogs; Hindlimb; Muscle, Skeletal / surgery; Orthopedic Procedures / veterinary; Plastic Surgery Procedures / veterinary; Suture Techniques / veterinary; Sutures / veterinary; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tendons / surgery; Tensile Strength; Transplantation, Autologous / veterinary
topics (OpenAlex): Tendon Structure and Treatment; Orthopedic Surgery and Rehabilitation; Shoulder Injury and Treatment
TL;DR: Autologous ATG augmentation as an adjunct to primary GT repair increased yield, peak and failure forces by approximately 1.6% and 2.1% respectively, which justify studies to determine the effect of ATG on clinical function following graft harvest in dogs. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: May 24, 2021

2021 journal article

Biomechanical evaluation of a novel barbed suture pattern with epitendinous suture augmentation in a canine flexor tendon model

Veterinary Surgery, 50(5), 1128–1136.

By: D. Duffy n, Y. Chang n, M. Fisher n & G. Moore*

MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dog Diseases / surgery; Dogs; Forelimb; Plastic Surgery Procedures / veterinary; Suture Techniques / veterinary; Sutures; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tendons / surgery; Tenotomy / veterinary; Tensile Strength
topics (OpenAlex): Surgical Sutures and Adhesives; Orthopedic Surgery and Rehabilitation; Dupuytren's Contracture and Treatments
TL;DR: The NBSP repair tested here may be advantageous over monofilament suture repair as it uses a similar-sized barbed core suture but eliminates the requirement for knot tying. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: May 17, 2021

2021 journal article

Effect of epitendinous suture caliber on the tensile strength of repaired canine flexor tendons

American Journal of Veterinary Research, 82(6), 510–515.

MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dog Diseases; Dogs; Suture Techniques / veterinary; Sutures / veterinary; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tendons / surgery; Tensile Strength
topics (OpenAlex): Orthopedic Surgery and Rehabilitation; Veterinary Orthopedics and Neurology; Surgical Sutures and Adhesives
Sources: Crossref, NC State University Libraries
Added: October 30, 2025

2021 journal article

Evaluation of a continuous locking novel epitendinous suture pattern with and without a core locking-loop suture on the biomechanical properties of tenorrhaphy constructs in an ex vivo model of canine superficial digital flexor tendon laceration

American Journal of Veterinary Research, 82(4), 302–309.

MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dog Diseases; Dogs; Lacerations / surgery; Lacerations / veterinary; Suture Techniques / veterinary; Sutures / veterinary; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tendons / surgery; Tensile Strength
topics (OpenAlex): Orthopedic Surgery and Rehabilitation; Veterinary Orthopedics and Neurology; Surgical Sutures and Adhesives
Sources: Crossref, NC State University Libraries
Added: October 23, 2025

2021 journal article

Ex vivo evaluation of novel core tenorrhaphy patterns in dogs

Veterinary Surgery, 50(6), 1316–1325.

By: K. Chiu n, D. Duffy n, Y. Chang n, L. Gaffney n & M. Fisher n

MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dog Diseases; Dogs; Random Allocation; Suture Techniques / veterinary; Sutures / veterinary; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tensile Strength
topics (OpenAlex): Orthopedic Surgery and Rehabilitation; Tendon Structure and Treatment; Veterinary Orthopedics and Neurology
TL;DR: Use of novel patterns ExDCrL, EmDCrl, and MTang improved resistance to loads and gap formation and were biomechanically superior compared to 3LP in healthy canine tendon repairs in dogs. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref
Added: July 12, 2021

2021 journal article

Extracellular Matrix Hydrogels Promote Expression of Muscle-Tendon Junction Proteins

Tissue Engineering Part A, 28(5-6), 270–282.

By: L. Gaffney n, Z. Davis n, C. Mora-Navarro n, M. Fisher n & D. Freytes n

author keywords: extracellular matrix; engineered tissues; myotendinous junction; paxillin
MeSH headings : Collagen / metabolism; Collagen Type I / metabolism; Culture Media, Conditioned; Extracellular Matrix / metabolism; Hydrogels; Muscles; Paxillin / metabolism; Tendons / metabolism
topics (OpenAlex): Tendon Structure and Treatment; Tissue Engineering and Regenerative Medicine; Sports injuries and prevention
Sources: Web Of Science, Crossref, NC State University Libraries
Added: November 15, 2021

2021 article

Extracellular Matrix Hydrogels Promote Expression of Muscle-Tendon Junction Proteins

Gaffney, L. S., Davis, Z. G., Mora-Navarro, C., Fisher, M. B., & Freytes, D. O. (2021, March 25). (Vol. 3). Vol. 3.

By: L. Gaffney n, Z. Davis n, C. Mora-Navarro n, M. Fisher n & D. Freytes n

topics (OpenAlex): Tendon Structure and Treatment; Tissue Engineering and Regenerative Medicine; Sports injuries and prevention; Osteoarthritis Treatment and Mechanisms; Shoulder Injury and Treatment
TL;DR: Tissue specific extracellular matrix (ECM) derived from muscle and tendon is used to determine how cells of each tissue interact with the microenvironment of the opposite tissue resulting in junction specific features and markers that should be included in tissue models of the muscletendon unit. (via Semantic Scholar)
Source: ORCID
Added: August 27, 2021

2021 journal article

Processing variables of direct-write, near-field electrospinning impact size and morphology of gelatin fibers

Biomedical Materials, 16(4), 045017.

By: Z. Davis n, A. Hussain* & M. Fisher n

author keywords: tissue engineering; gelatin; additive manufacturing; direct-write electrospinning; parametric control
MeSH headings : Biopolymers / chemistry; Electrochemical Techniques / methods; Gelatin / chemistry; Nanofibers / chemistry; Nanotechnology; Tissue Engineering; Tissue Scaffolds / chemistry
topics (OpenAlex): Electrospun Nanofibers in Biomedical Applications; 3D Printing in Biomedical Research; Additive Manufacturing and 3D Printing Technologies
TL;DR: This system is capable of replicating the fibrous structure of musculoskeletal tissues with biologically relevant materials which will provide a durable platform for the analysis of single cell-fiber interactions to help better understand the impact scaffold materials and dimensions have on cell behavior. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: May 24, 2021

2021 article

Sex-Specific Function and Morphology of the Anterior Cruciate Ligament During Skeletal Growth in a Porcine Model

Howe, D., Cone, S. G., Piedrahita, J. A., Collins, B., Fordham, L. A., Griffith, E. H., … Fisher, M. B. (2021, May 10). (Vol. 5). Vol. 5.

topics (OpenAlex): Knee injuries and reconstruction techniques; Sports injuries and prevention; Total Knee Arthroplasty Outcomes
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3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: October 22, 2025

2021 journal article

Sex‐specific biomechanics and morphology of the anterior cruciate ligament during skeletal growth in a porcine model

Journal of Orthopaedic Research, 40(8), 1853–1864.

author keywords: anterior cruciate ligament; knee; porcine model; skeletal growth
MeSH headings : Adolescent; Aged; Animals; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Biomechanical Phenomena; Child; Female; Humans; Joint Instability; Knee Joint; Male; Swine; Tibia
topics (OpenAlex): Knee injuries and reconstruction techniques; Sports injuries and prevention; Total Knee Arthroplasty Outcomes
TL;DR: A porcine model is used to investigate the sex-specific morphology and biomechanics of the ACL and its bundles throughout skeletal growth and has implications for age and sex‐specific surgical intervention strategies and suggests the need for human studies. (via Semantic Scholar)
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3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: November 15, 2021

2021 conference paper

Structure-Function Characterization of Nonwoven Scaffolds Fabricated Via High Throughput 3D Melt Blowing

2021 International Conference on Biofabrication. Poster presented at the 2021 International Conference on Biofabrication.

By: K. Schuchard, A. Pawar, B. Anderson, B. Pourdeyhimi, M. Fisher & R. Shirwaiker

Event: 2021 International Conference on Biofabrication on September 27-29, 2021

Source: NC State University Libraries
Added: November 21, 2025

2020 journal article

Assessment of skin staples for augmentation of core tenorrhaphy in an ex vivo model of canine superficial digital flexor tendon laceration

American Journal of Veterinary Research, 81(8), 681–688.

MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dog Diseases; Dogs; Lacerations / surgery; Lacerations / veterinary; Suture Techniques / veterinary; Sutures; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tendons / surgery; Tensile Strength
topics (OpenAlex): Orthopedic Surgery and Rehabilitation; Surgical Sutures and Adhesives; Veterinary Orthopedics and Neurology
Sources: Crossref, NC State University Libraries
Added: October 23, 2025

2020 journal article

Biomechanical evaluation of an autologous flexor digitorum lateralis graft to augment the surgical repair of gastrocnemius tendon laceration in a canine ex vivo model

Veterinary Surgery, 49(8), 1545–1554.

By: D. Duffy n, C. Curcillo n, Y. Chang n, L. Gaffney n, M. Fisher n & G. Moore*

MeSH headings : Animals; Autografts / physiology; Biomechanical Phenomena; Cadaver; Dogs / injuries; Dogs / surgery; Lacerations / surgery; Lacerations / veterinary; Muscle, Skeletal / surgery; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tendons / transplantation; Transplantation, Autologous / veterinary
topics (OpenAlex): Tendon Structure and Treatment; Orthopedic Surgery and Rehabilitation; Shoulder Injury and Treatment
TL;DR: Use of FDL tendon augmentation for GT laceration may increase repair site strength and resist gap formation better than 3LP core suture use alone and increase yield, peak, and failure forces by twofold, 2.3-fold and 2.2-fold compared with core 3LP alone while preventing the occurrence of gap formation. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: November 24, 2020

2020 journal article

Effect of partial vs complete circumferential epitendinous suture placement on the biomechanical properties and gap formation of canine cadaveric tendons

Veterinary Surgery, 49(8), 1571–1579.

By: D. Duffy n, Y. Chang n, M. Fisher n & G. Moore*

MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dogs / injuries; Dogs / surgery; Plastic Surgery Procedures / veterinary; Suture Techniques / veterinary; Sutures / veterinary; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tendons / surgery; Tensile Strength
topics (OpenAlex): Orthopedic Surgery and Rehabilitation; Surgical Sutures and Adhesives; Tendon Structure and Treatment
TL;DR: Addition of a complete circumferential ES with a single or double knotting technique increased the biomechanical strength of normal tendon repairs while reducing gap formation compared with partial ES placement alone. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref
Added: September 7, 2020

2020 journal article

Fibrin‐based biomaterial systems to enhance anterior cruciate ligament healing

MEDICAL DEVICES & SENSORS, 4(1).

By: G. Scull n, M. Fisher n & A. Brown n

topics (OpenAlex): Knee injuries and reconstruction techniques; Periodontal Regeneration and Treatments; Tendon Structure and Treatment
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3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: May 17, 2024

2020 journal article

High-Throughput Manufacture of 3D Fiber Scaffolds for Regenerative Medicine

Tissue Engineering Part C: Methods, 26(7), 364–374.

By: R. Shirwaiker n, M. Fisher n, B. Anderson n, K. Schuchard n, P. Warren n, B. Maze n, P. Grondin n, F. Ligler n, B. Pourdeyhimi n

Contributors: R. Shirwaiker n, M. Fisher n, B. Anderson n, K. Schuchard n, P. Warren n, B. Maze n, P. Grondin n, F. Ligler n, B. Pourdeyhimi n

author keywords: 3D printing; melt blowing; fibers; scaffolds
MeSH headings : Animals; Biocompatible Materials / chemistry; Dogs; Hernia / therapy; Herniorrhaphy / methods; Polymers / chemistry; Printing, Three-Dimensional / instrumentation; Regenerative Medicine; Tissue Engineering / methods; Tissue Scaffolds / chemistry
topics (OpenAlex): Electrospun Nanofibers in Biomedical Applications; Tissue Engineering and Regenerative Medicine; Additive Manufacturing and 3D Printing Technologies
TL;DR: The 3DMB system described in this study is modified from larger nonwovens manufacturing machinery to accommodate the lower volume, high-cost polymers used for tissue engineering and implantable biomedical devices and has a fiber collection component that uses adaptable robotics to create scaffolds with predetermined geometries. (via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: August 10, 2020

2020 journal article

Influence of barbed epitendinous sutures combined with a core locking‐loop suture to repair experimental flexor tendon lacerations

Veterinary Surgery, 49(8), 1590–1599.

By: A. Eby n, D. Duffy n, Y. Chang n, L. Gaffney n, M. Fisher n & G. Moore*

MeSH headings : Animals; Cadaver; Dogs / injuries; Dogs / surgery; Lacerations / surgery; Lacerations / veterinary; Plastic Surgery Procedures / veterinary; Suture Techniques / veterinary; Sutures / veterinary; Tendon Injuries / surgery; Tendon Injuries / veterinary; Tendons / surgery; Tensile Strength
topics (OpenAlex): Surgical Sutures and Adhesives; Orthopedic Surgery and Rehabilitation; Tendon Structure and Treatment
TL;DR: Investigating the influence of barbed epitendinous sutures on the biomechanical properties and gap formation of repaired canine tendons found Stratafix barbed suture performed better as an ES compared with other barbedSutures and similarly to monofilament suture. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries
Added: September 28, 2020

2020 journal article

Integrated iterative musculoskeletal modeling predicts bone morphology following brachial plexus birth injury (BPBI)

Journal of Biomechanics, 103, 109658.

By: N. Dixit n, D. McFarland n, M. Fisher n, J. Cole n & K. Saul n

Contributors: N. Dixit n, D. McFarland n, M. Fisher n, J. Cole n & K. Saul n

author keywords: Brachial plexus birth injury; Preganglionic; Postganglionic; Finite element; Computational model; Bone growth; Musculoskeletal
MeSH headings : Birth Injuries; Brachial Plexus / injuries; Brachial Plexus Neuropathies; Child; Humans; Scapula; Shoulder Joint
topics (OpenAlex): Nerve Injury and Rehabilitation; Cardiac Structural Anomalies and Repair; Spinal Fractures and Fixation Techniques
TL;DR: Differences in muscle mass and length between the pre ganglionic and postganglionic injuries are critical mechanical drivers of the altered glenohumeral joint shape. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: April 4, 2022

2020 journal article

Joint laxity varies in response to partial and complete anterior cruciate ligament injuries throughout skeletal growth

Journal of Biomechanics, 101, 109636.

author keywords: Anterior cruciate ligament; Pediatric; Injury; Joint mechanics; Animal model
MeSH headings : Animals; Anterior Cruciate Ligament Injuries / complications; Biomechanical Phenomena; Female; Joint Instability / complications; Joint Instability / physiopathology; Rotation; Stifle / growth & development; Stifle / physiopathology; Swine
topics (OpenAlex): Knee injuries and reconstruction techniques; Sports injuries and prevention; Total Knee Arthroplasty Outcomes
TL;DR: At all ages, the medial collateral ligament and the medial meniscus combined to resist the majority of applied anterior tibial load following complete ACL transection, adding to the current understanding of age-specific functional properties of both healthy and injured knees during skeletal growth. (via Semantic Scholar)
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5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: March 23, 2020

2020 article

Processing variables of direct-write, near-field electrospinning impact size and morphology of gelatin fibers

Davis, Z. G., Hussain, A. F., & Fisher, M. B. (2020, September 19). (Vol. 9). Vol. 9.

By: Z. Davis n, A. Hussain n & M. Fisher n

topics (OpenAlex): Electrospun Nanofibers in Biomedical Applications; 3D Printing in Biomedical Research; Additive Manufacturing and 3D Printing Technologies
Source: ORCID
Added: August 27, 2021

2019 article

Biomechanical Function and Size of the Anteromedial and Posterolateral Bundles of the ACL Change Differently with Skeletal Growth in the Pig Model

CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, Vol. 477, pp. 2161–2174.

By: S. Cone, E. Lambeth, H. Ru, L. Fordham, J. Piedrahita, J. Spang, M. Fisher

MeSH headings : Aging / physiology; Animals; Anterior Cruciate Ligament / physiology; Biomechanical Phenomena; Cadaver; Models, Animal; Musculoskeletal Development / physiology; Range of Motion, Articular / physiology; Rotation; Swine; Tibia / physiology; Torque
topics (OpenAlex):
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5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: February 17, 2020

2019 journal article

Effect of bite depth of an epitendinous suture on the biomechanical strength of repaired canine flexor tendons

American Journal of Veterinary Research, 80(11), 1043–1049.

By: D. Duffy n, Y. Chang n, L. Gaffney n, M. Fisher n & G. Moore*

MeSH headings : Animals; Biomechanical Phenomena; Cadaver; Dogs / surgery; Suture Techniques / veterinary; Tendon Injuries; Tendons / surgery; Tensile Strength
topics (OpenAlex): Orthopedic Surgery and Rehabilitation; Tendon Structure and Treatment; Surgical Sutures and Adhesives
TL;DR: Increasing bite depth of an epitendinous suture toward the center of the tendon substance increased repair site strength and decreased the incidence of gap formation. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: April 20, 2020

2019 journal article

In Situ Joint Stiffness Increases During Skeletal Growth but Decreases Following Partial and Complete Anterior Cruciate Ligament Injury

Journal of Biomechanical Engineering, 141(12).

By: S. Cone n, J. Piedrahita n, J. Spang* & M. Fisher n

topics (OpenAlex): Knee injuries and reconstruction techniques; Sports injuries and prevention; Cardiovascular Effects of Exercise
TL;DR: This work furthers the understanding of the interaction between joint biomechanics and ACL function throughout growth and the impact of ACL injury in the skeletally immature joint. (via Semantic Scholar)
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3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: January 27, 2020

2019 journal article

Mechanical properties of tissue formed in vivo are affected by 3D-bioplotted scaffold microarchitecture and correlate with ECM collagen fiber alignment

Connective Tissue Research, 61(2), 190–204.

By: P. Huebner n, P. Warren n, D. Chester n, J. Spang*, A. Brown n, M. Fisher n, R. Shirwaiker n

author keywords: 3D printing; atomic force microscopy; elastic modulus; tissue engineering; tissue scaffolds
MeSH headings : Animals; Bioprinting; Collagen / chemistry; Extracellular Matrix / chemistry; Male; Polyesters / chemistry; Printing, Three-Dimensional; Rats; Rats, Sprague-Dawley; Tissue Engineering; Tissue Scaffolds / chemistry
topics (OpenAlex): Electrospun Nanofibers in Biomedical Applications; Bone Tissue Engineering Materials; Tissue Engineering and Regenerative Medicine
TL;DR: The findings demonstrate the significant effects of 3D-bioplotted scaffold microarchitectures in the organization and sub-tissue-level mechanical properties of ECM in vivo. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 26, 2019

2019 journal article

Parametric control of fiber morphology and tensile mechanics in scaffolds with high aspect ratio geometry produced via melt electrowriting for musculoskeletal soft tissue engineering

Journal of the Mechanical Behavior of Biomedical Materials, 99, 153–160.

By: P. Warren n, Z. Davis n & M. Fisher n

author keywords: Musculoskeletal soft tissue; Additive manufacturing; Scaffold geometry; Tissue engineering
MeSH headings : Anisotropy; Biomimetics; Collagen / chemistry; Electrochemistry; Extracellular Matrix / metabolism; Materials Testing; Temperature; Tensile Strength; Tissue Engineering / instrumentation; Tissue Engineering / methods; Tissue Scaffolds / chemistry
topics (OpenAlex): Additive Manufacturing and 3D Printing Technologies; Electrospun Nanofibers in Biomedical Applications; 3D Printing in Biomedical Research
TL;DR: The need to tailor MEW process parameters in scaffolds with high aspect ratio geometry in order to consistently generate specific structural and mechanical properties is highlighted. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: September 30, 2019

2019 journal article

Size and Shape of the Human Anterior Cruciate Ligament and the Impact of Sex and Skeletal Growth

JBJS Reviews, 7(6), e8–e8.

By: S. Cone n, D. Howe n & M. Fisher n

MeSH headings : Anterior Cruciate Ligament / anatomy & histology; Anterior Cruciate Ligament / physiology; Anterior Cruciate Ligament Injuries / surgery; Anterior Cruciate Ligament Reconstruction / methods; Bone Development / physiology; Decision Support Techniques; Evidence-Based Medicine / classification; Graft Survival; Humans; Qualitative Research; Sex Factors
topics (OpenAlex): Knee injuries and reconstruction techniques; Lower Extremity Biomechanics and Pathologies
TL;DR: The present study condenses measurements describing the geometry of the ACL, its individual bundles, and its insertion sites, accounting for common covariates when possible, to provide a resource to the clinical and scientific communities. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: September 3, 2019

2019 journal article

Tissue-specific changes in size and shape of the ligaments and tendons of the porcine knee during post-natal growth

PLOS ONE, 14(10), e0219637.

By: S. Cone n, H. Piercy n, E. Lambeth n, H. Ru n, J. Piedrahita n, J. Spang*, L. Fordham*, M. Fisher n

Ed(s): A. Almarza

MeSH headings : Animals; Anterior Cruciate Ligament / diagnostic imaging; Anterior Cruciate Ligament / growth & development; Female; Knee Joint / diagnostic imaging; Knee Joint / growth & development; Magnetic Resonance Imaging; Organ Specificity; Patellar Ligament / diagnostic imaging; Patellar Ligament / growth & development; Swine
topics (OpenAlex): Knee injuries and reconstruction techniques; Lower Extremity Biomechanics and Pathologies; Tendon Structure and Treatment
TL;DR: The findings suggest that musculoskeletal soft tissue morphometry can vary within tissues of similar structure and within a single joint during post-natal growth. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: June 8, 2020

2019 article

Tissue-specific changes in size and shape of the ligaments and tendons of the porcine knee during post-natal growth

Cone, S. G., Piercy, H. E., Lambeth, E. P., Ru, H., Piedrahita, J. A., Spang, J. T., … Fisher, M. B. (2019, July 1). (Vol. 7). Vol. 7.

topics (OpenAlex): Knee injuries and reconstruction techniques; Tendon Structure and Treatment; Sports injuries and prevention
Source: ORCID
Added: October 22, 2025

2018 article

Mechanical Anisotropy Assessment in Kidney Cortex Using ARFI Peak Displacement: Preclinical Validation and Pilot <italic>In Vivo</italic> Clinical Results in Kidney Allografts

Hossain, M. M., Detwiler, R. K., Chang, E. H., Caughey, M. C., Fisher, M. W., Nichols, T. C., … Gallippi, C. M. (2018, August 13). IEEE Transactions on Ultrasonics Ferroelectrics and Frequency Control, Vol. 66, pp. 551–562.

By: M. Hossain n, R. Detwiler*, E. Chang*, M. Caughey*, M. Fisher*, T. Nichols*, E. Merricks*, R. Raymer* ...

author keywords: Acoustic radiation force impulse (ARFI); anisotropy; chronic kidney disease (CKD); kidney transplant; renal rejection; shear wave elasticity imaging (SWEI); ultrasound
MeSH headings : Adult; Aged; Allografts / diagnostic imaging; Allografts / physiology; Animals; Anisotropy; Elastic Modulus / physiology; Elasticity Imaging Techniques / methods; Female; Humans; Kidney Cortex / diagnostic imaging; Kidney Cortex / physiology; Kidney Transplantation; Male; Middle Aged; Renal Insufficiency, Chronic / diagnostic imaging; Renal Insufficiency, Chronic / surgery; Swine
topics (OpenAlex): Ultrasound Imaging and Elastography; Ultrasound and Hyperthermia Applications; Electrical and Bioimpedance Tomography
TL;DR: The results of this pilot clinical study suggest the feasibility of implementing symmetrical ARF to obviate mechanical anisotropy in the kidney cortex when anisOTropy is a confounding factor and implementing asymmetric ARF in the cortex of human kidney allografts to exploit mechanical an isotropy when mechanicalAnisotropic biomarker is a potentially relevant biomarker. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 2, 2019

2017 journal article

Age-Dependent Subchondral Bone Remodeling and Cartilage Repair in a Minipig Defect Model

Tissue Engineering Part C: Methods, 23(11), 745–753.

By: C. Pfeifer*, M. Fisher*, V. Saxena*, M. Kim*, E. Henning*, D. Steinberg*, G. Dodge*, R. Mauck*

author keywords: subchondral bone; cartilage; microfracture; skeletal maturity
MeSH headings : Aging / physiology; Animals; Bone Remodeling; Cartilage, Articular / diagnostic imaging; Cartilage, Articular / pathology; Cartilage, Articular / surgery; Collagen Type II / metabolism; Disease Models, Animal; Fluoroscopy; Immunohistochemistry; Male; Proteoglycans / metabolism; Swine; Swine, Miniature; Wound Healing; X-Ray Microtomography
topics (OpenAlex): Osteoarthritis Treatment and Mechanisms; Knee injuries and reconstruction techniques; Lower Extremity Biomechanics and Pathologies
TL;DR: The significant impact of skeletal maturity on the propensity of subchondral bone to remodel as a result of chondral injury is shown to improve selection criteria for animal models for studying cartilage injury, repair, and treatment. (via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2017 journal article

Biphasic Finite Element Modeling Reconciles Mechanical Properties of Tissue-Engineered Cartilage Constructs Across Testing Platforms

Tissue Engineering Part A, 23(13-14), 663–674.

By: G. Meloni*, M. Fisher n, B. Stoeckl*, G. Dodge* & R. Mauck*

author keywords: mechanical evaluation; mesenchymal stem cells; cartilage tissue engineering
MeSH headings : Animals; Cartilage / chemistry; Cartilage / cytology; Cartilage / metabolism; Cattle; Finite Element Analysis; Tissue Engineering
topics (OpenAlex): Osteoarthritis Treatment and Mechanisms; Knee injuries and reconstruction techniques; Periodontal Regeneration and Treatments
TL;DR: Finite element (FE) models (using FEBio) of unconfined compression and indentation testing, modalities commonly used for in vitro grown samples, showed significant changes in material properties during the maturation of engineered cartilage tissue, capturing dynamic changes in functional tissue mechanics. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Macrophages' role in tissue disease and regeneration

Macrophages: Origin, Functions and Biointervention, 62, 245–271.

By: L. Gaffney, P. Warren, E. Wrona, M. Fisher & D. Freytes

Source: NC State University Libraries
Added: August 6, 2018

2017 chapter book

Macrophages’ Role in Tissue Disease and Regeneration

By: L. Gaffney n, P. Warren n, E. Wrona n, M. Fisher n & D. Freytes*

Contributors: L. Gaffney n, P. Warren n, E. Wrona n, M. Fisher n & D. Freytes*

MeSH headings : Animals; Humans; Inflammation / immunology; Macrophages / immunology; Regeneration / immunology; Regenerative Medicine; Tissue Engineering; Wound Healing / immunology
topics (OpenAlex): Macrophage Migration Inhibitory Factor; Connective tissue disorders research; Extracellular vesicles in disease
TL;DR: The role of macrophages in specific cases of injury and disease is described and enhanced therapeutic treatments can be developed that enhance the normal healing response as well as help the survival of therapeutic cells delivered to the site of injury. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 10, 2019

2017 journal article

Orientation changes in the cruciate ligaments of the knee during skeletal growth: A porcine model

Journal of Orthopaedic Research, 35(12), 2725–2732.

author keywords: anterior cruciate ligament; posterior cruciate ligament; adolescent; porcine; MRI
MeSH headings : Animals; Anterior Cruciate Ligament / diagnostic imaging; Anterior Cruciate Ligament / growth & development; Female; Magnetic Resonance Imaging; Posterior Cruciate Ligament / diagnostic imaging; Posterior Cruciate Ligament / growth & development; Swine
topics (OpenAlex): Knee injuries and reconstruction techniques; Sports injuries and prevention; Lower Extremity Biomechanics and Pathologies
TL;DR: The age‐dependent properties of the ACL and PCL in the female pig mirrored results found in female human patients, suggesting that the porcine model may provide a pre‐clinical platform to study the cruciate ligaments during skeletal growth. (via Semantic Scholar)
Sources: Web Of Science, ORCID, Crossref, NC State University Libraries
Added: August 6, 2018

2017 journal article

Rise of the Pigs: Utilization of the Porcine Model to Study Musculoskeletal Biomechanics and Tissue Engineering During Skeletal Growth

Tissue Engineering Part C: Methods, 23(11), 763–780.

By: S. Cone n, P. Warren n & M. Fisher n

author keywords: animal models; ligament and tendon; cartilage; bone; skeletal muscle
MeSH headings : Animals; Biomechanical Phenomena; Bone Development; Models, Animal; Musculoskeletal Physiological Phenomena; Regenerative Medicine; Sus scrofa; Tissue Engineering
topics (OpenAlex): Muscle Physiology and Disorders; Xenotransplantation and immune response; Tissue Engineering and Regenerative Medicine
TL;DR: This review explores the publication history of the use of pig models in biomechanics and TERM discuss interspecies comparative studies, highlight studies on the effect of skeletal growth and other biological considerations in the porcine model, and present challenges and emerging opportunities for using this model to study functional TERM. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Transforming Growth Factor-β2 Downregulates Major Histocompatibility Complex (MHC) I and MHC II Surface Expression on Equine Bone Marrow-Derived Mesenchymal Stem Cells Without Altering Other Phenotypic Cell Surface Markers

Frontiers in Veterinary Science, 4.

By: A. Berglund n, M. Fisher n, K. Cameron n, E. Poole n & L. Schnabel n

topics (OpenAlex): Mesenchymal stem cell research; Immunotherapy and Immune Responses; Immune cells in cancer
Sources: Crossref, NC State University Libraries
Added: March 10, 2025

2016 journal article

3D-Bioprinting of Polylactic Acid (PLA) Nanofiber–Alginate Hydrogel Bioink Containing Human Adipose-Derived Stem Cells

ACS Biomaterials Science & Engineering, 2(10), 1732–1742.

By: L. Narayanan n, P. Huebner n, M. Fisher n, J. Spang*, B. Starly n & R. Shirwaiker n

Contributors: L. Narayanan n, P. Huebner n, M. Fisher n, J. Spang*, B. Starly n & R. Shirwaiker n

author keywords: bioprinting; knee meniscus; alginate; nanofibers; adipose-derived stem cells; musculoskeletal soft tissue
topics (OpenAlex): 3D Printing in Biomedical Research; Bone Tissue Engineering Materials; Additive Manufacturing and 3D Printing Technologies
TL;DR: This study focuses on the development and proof-of-concept assessment of a fibrous bioink composed of alginate hydrogel, polylactic acid nanofibers, and human adipose-derived stem cells for bioprinting such tissue constructs and shows that the nanofiber-reinforced bioink allowed higher levels of cell proliferation within biopprinted strands. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Engineering 3D-Bioplotted scaffolds to induce aligned extracellular matrix deposition for musculoskeletal soft tissue replacement

Connective Tissue Research, 58(3-4), 342–354.

By: P. Warren n, P. Huebner n, J. Spang*, R. Shirwaiker n & M. Fisher n

Contributors: P. Warren n, P. Huebner n, J. Spang*, R. Shirwaiker n & M. Fisher n

author keywords: Biofabrication; meniscus; tissue engineering; scaffold; 3D printing
MeSH headings : Animals; Cell Count; Cell Shape; Collagen / metabolism; Extracellular Matrix / metabolism; Imaging, Three-Dimensional; Male; Musculoskeletal Physiological Phenomena; Rats, Sprague-Dawley; Regeneration / physiology; Sus scrofa; Tissue Engineering / methods; Tissue Scaffolds / chemistry
topics (OpenAlex): Electrospun Nanofibers in Biomedical Applications; Bone Tissue Engineering Materials; Tissue Engineering and Regenerative Medicine
TL;DR: The ability to use interstrand spacing as a means of controlling the formation of aligned collagen in vivo was demonstrated, which helps establish a design space for scaffold-based meniscus tissue engineering. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Enhanced cellular infiltration of human adipose-derived stem cells in allograft menisci using a needle-punch method

Journal of Orthopaedic Surgery and Research, 11(1).

MeSH headings : Adipose Tissue / cytology; Adipose Tissue / physiology; Adipose Tissue / transplantation; Adult; Allografts / cytology; Allografts / physiology; Cell Survival / physiology; Cells, Cultured; Female; Humans; Male; Meniscus / cytology; Meniscus / physiology; Meniscus / transplantation; Middle Aged; Needles; Stem Cell Transplantation / methods; Stem Cells / physiology; Transplantation, Homologous / methods
topics (OpenAlex): Knee injuries and reconstruction techniques; Total Knee Arthroplasty Outcomes; Tendon Structure and Treatment
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2015 journal article

Development of a Large Animal Model of Osteochondritis Dissecans of the Knee

Orthopaedic Journal of Sports Medicine, 3(2).

By: C. Pfeifer*, S. Kinsella*, A. Milby*, M. Fisher*, N. Belkin*, R. Mauck*, J. Carey*

topics (OpenAlex): Knee injuries and reconstruction techniques; Osteoarthritis Treatment and Mechanisms; Total Knee Arthroplasty Outcomes
Sources: Crossref, NC State University Libraries
Added: October 23, 2025

2015 journal article

Effects of Mesenchymal Stem Cell and Growth Factor Delivery on Cartilage Repair in a Mini-Pig Model

CARTILAGE, 7(2), 174–184.

By: M. Fisher n, N. Belkin*, A. Milby*, E. Henning*, N. Söegaard*, M. Kim*, C. Pfeifer*, V. Saxena* ...

author keywords: cartilage; repair; mesenchymal stem cells; TGF-3; animal models
topics (OpenAlex): Osteoarthritis Treatment and Mechanisms; Periodontal Regeneration and Treatments; Mesenchymal stem cell research
TL;DR: At this early healing time point, treatment with TGF-β3 promoted the formation of collagen type II within the defect, while allogeneic MSCs had little benefit. (via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2015 journal article

Engineering meniscus structure and function via multi-layered mesenchymal stem cell-seeded nanofibrous scaffolds

Journal of Biomechanics, 48(8), 1412–1419.

By: M. Fisher n, E. Henning*, N. Söegaard*, M. Bostrom*, J. Esterhai* & R. Mauck*

author keywords: Tissue engineering; Meniscus; Nanofibrous scaffold; Electrospinning; Mechanical properties
MeSH headings : Animals; Cattle; Cells, Cultured; Collagen / metabolism; Elastic Modulus; Materials Testing; Menisci, Tibial / pathology; Mesenchymal Stem Cells / physiology; Nanofibers / chemistry; Polyesters / chemistry; Tissue Engineering; Tissue Scaffolds / chemistry
topics (OpenAlex): Knee injuries and reconstruction techniques; Total Knee Arthroplasty Outcomes; Polymer Surface Interaction Studies
TL;DR: This study developed multi-lamellar mesenchymal stem cell-seeded nanofibrous constructs that may serve as functional substitutes for the meniscus as well as test beds to understand the complex mechanical principles that enable meniscUS function. (via Semantic Scholar)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2015 journal article

Fibrous Scaffolds with Varied Fiber Chemistry and Growth Factor Delivery Promote Repair in a Porcine Cartilage Defect Model

Tissue Engineering Part A, 21(21-22), 2680–2690.

By: I. Kim*, C. Pfeifer*, M. Fisher*, V. Saxena*, G. Meloni*, M. Kwon*, M. Kim*, D. Steinberg*, R. Mauck*, J. Burdick*

MeSH headings : Animals; Compressive Strength; Drug Implants / administration & dosage; Equipment Failure Analysis; Fractures, Cartilage / pathology; Fractures, Cartilage / therapy; Guided Tissue Regeneration / instrumentation; Humans; Intercellular Signaling Peptides and Proteins / administration & dosage; Intercellular Signaling Peptides and Proteins / chemistry; Materials Testing; Nanofibers / chemistry; Nanofibers / ultrastructure; Prosthesis Design; Stress, Mechanical; Swine; Swine, Miniature; Tensile Strength; Tissue Scaffolds; Transforming Growth Factor beta3 / administration & dosage; Transforming Growth Factor beta3 / chemistry; Treatment Outcome
topics (OpenAlex): Osteoarthritis Treatment and Mechanisms; Periodontal Regeneration and Treatments; Electrospun Nanofibers in Biomedical Applications
Sources: Crossref, NC State University Libraries
Added: October 30, 2025

2015 journal article

Impact of guidance documents on translational large animal studies of cartilage repair

Science Translational Medicine, 7(310).

By: C. Pfeifer*, M. Fisher n, J. Carey* & R. Mauck*

MeSH headings : Animals; Cartilage / physiopathology; Models, Animal; Translational Research, Biomedical; United States; United States Food and Drug Administration
topics (OpenAlex): Osteoarthritis Treatment and Mechanisms; Delphi Technique in Research; Knee injuries and reconstruction techniques; Molecular Biology Techniques and Applications; Inflammatory mediators and NSAID effects
TL;DR: A systematic review of large animal cartilage repair studies demonstrates that few investigators attend to guidance documents published by regulatory agencies, and the availability of the documents appears to have little effect on adherence by researchers to the recommendations therein. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2015 journal article

Meniscus mechanics and mechanobiology

Journal of Biomechanics, 48(8), 1341–1342.

By: T. Donahue*, M. Fisher n & S. A. Maher*

topics (OpenAlex): Knee injuries and reconstruction techniques; Lower Extremity Biomechanics and Pathologies; Tendon Structure and Treatment
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Cartilage Repair and Subchondral Bone Remodeling in Response to Focal Lesions in a Mini-Pig Model: Implications for Tissue Engineering

Tissue Engineering Part A, 21(3-4), 850–860.

By: M. Fisher*, N. Belkin*, A. Milby*, E. Henning*, M. Bostrom*, M. Kim*, C. Pfeifer*, G. Meloni* ...

MeSH headings : Animals; Bone Remodeling / physiology; Cartilage / transplantation; Fracture Healing / physiology; Fractures, Cartilage / diagnostic imaging; Fractures, Cartilage / therapy; Radiography; Swine; Swine, Miniature; Tissue Engineering / methods; Tissue Scaffolds; Treatment Outcome
topics (OpenAlex): Osteoarthritis Treatment and Mechanisms; Knee injuries and reconstruction techniques; Periodontal Regeneration and Treatments
Sources: Crossref, NC State University Libraries
Added: October 23, 2025

2014 journal article

Repair of dense connective tissues via biomaterial-mediated matrix reprogramming of the wound interface

Biomaterials, 39, 85–94.

By: F. Qu*, M. Pintauro*, J. Haughan*, E. Henning*, J. Esterhai*, T. Schaer*, R. Mauck*, M. Fisher*

author keywords: Connective tissue; Drug delivery; ECM (extracellular matrix); In vivo test; Scaffold; Wound healing
MeSH headings : Animals; Biocompatible Materials / chemistry; Connective Tissue / physiology; Microscopy, Atomic Force; Polyethylene Glycols / chemistry; Rats; Sheep; Tissue Scaffolds / chemistry; Wound Healing / physiology
topics (OpenAlex): Wound Healing and Treatments; Tendon Structure and Treatment; Periodontal Regeneration and Treatments
TL;DR: Findings show that partial digestion of the wound interface improves repair by creating a more compliant and porous microenvironment that expedites cell migration to and/or proliferation at the wound margin. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: December 19, 2020

2013 journal article

Biomaterial-mediated delivery of degradative enzymes to improve meniscus integration and repair

Acta Biomaterialia, 9(5), 6393–6402.

By: F. Qu*, J. Lin*, J. Esterhai*, M. Fisher* & R. Mauck*

author keywords: Drug delivery; Enzyme; Meniscus tear; Nanofibrous scaffold; Wound healing
MeSH headings : Animals; Biocompatible Materials; Cattle; Enzymes / administration & dosage; Enzymes / metabolism; Knee Joint / pathology; Microscopy, Electron, Scanning
topics (OpenAlex): Knee injuries and reconstruction techniques; Tendon Structure and Treatment; Periodontal Regeneration and Treatments
TL;DR: An innovative approach to targeted enzyme delivery may aid the many patients that exhibit meniscal tears by promoting integration of the defect, thereby circumventing the pathologic consequences of partial meniscus removal, and may find widespread application in the treatment of injuries to a variety of dense connective tissues. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: December 19, 2020

2013 journal article

Functional properties of bone marrow-derived MSC-based engineered cartilage are unstable with very long-term in vitro culture

Journal of Biomechanics, 47(9), 2173–2182.

By: M. Farrell*, M. Fisher*, A. Huang*, J. Shin*, K. Farrell* & R. Mauck*

author keywords: Mesenchymal stem cells; Chondrogenesis; Three-dimensional culture; Cartilage; Mechanical properties
MeSH headings : Animals; Bone Marrow Cells / cytology; Cartilage / cytology; Cartilage / metabolism; Cattle; Cell Survival; Cells, Cultured; Chondrocytes / cytology; Chondrogenesis; Femur; Glycosaminoglycans / metabolism; Hydrogels; Mesenchymal Stem Cells / cytology; Sepharose; Tissue Engineering / methods; Tissue Scaffolds
topics (OpenAlex): Osteoarthritis Treatment and Mechanisms; Periodontal Regeneration and Treatments; Knee injuries and reconstruction techniques
TL;DR: Data suggest that, even within a controlled in vitro environment that is conducive to chondrogenesis, there may be an innate instability in the MSC phenotype that is independent of scaffold composition, and may ultimately limit their application in functional cartilage repair. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: December 19, 2020

2013 journal article

Maximizing cartilage formation and integration via a trajectory-based tissue engineering approach

Biomaterials, 35(7), 2140–2148.

By: M. Fisher*, E. Henning*, N. Söegaard*, G. Dodge*, D. Steinberg* & R. Mauck*

author keywords: Tissue engineering; Hyaluronic acid; Hydrogels; Cartilage; Integration; Maturation
MeSH headings : Animals; Cartilage / growth & development; Cattle; Tissue Engineering
topics (OpenAlex): Osteoarthritis Treatment and Mechanisms; Knee injuries and reconstruction techniques; Periodontal Regeneration and Treatments
TL;DR: It is shown that integration to cartilage in-vitro is not correlated to the maturation state of TE constructs, but rather their maturation rate, providing a proof-of-concept for the use of TB-TE to enhance treatment outcomes following cartilage injury. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: December 19, 2020

2013 journal article

Starting with Form, Emerging with Function: Nanofibrous Scaffolds for Tissue Engineering of Orthopedic Tissues

Nanomedicine, 8(4), 505–508.

By: M. Fisher* & R. Mauck*

MeSH headings : Humans; Knee Joint / surgery; Orthopedics / methods; Tissue Engineering / methods; Tissue Scaffolds
topics (OpenAlex): Electrospun Nanofibers in Biomedical Applications; Tissue Engineering and Regenerative Medicine; Connective tissue disorders research
Sources: Crossref, NC State University Libraries
Added: October 30, 2025

2012 journal article

Organized nanofibrous scaffolds that mimic the macroscopic and microscopic architecture of the knee meniscus

Acta Biomaterialia, 9(1), 4496–4504.

By: M. Fisher*, E. Henning*, N. Söegaard*, J. Esterhai* & R. Mauck*

author keywords: Tissue engineering; Meniscus; Nanofibrous scaffold; Electrospinning; Mechanical properties
MeSH headings : Materials Testing; Menisci, Tibial / anatomy & histology; Menisci, Tibial / ultrastructure; Microscopy, Electron, Scanning; Molecular Mimicry; Nanostructures; Tissue Engineering; Tissue Scaffolds
topics (OpenAlex): Knee injuries and reconstruction techniques; Electrospun Nanofibers in Biomedical Applications; Polymer Surface Interaction Studies
TL;DR: A novel electrospinning method to produce scaffolds composed of circumferentially aligned (CircAl) nanofibers, quantified their structure and mechanics, and compared them with traditional linearly aligned (LinAl) scaffolds will enable the formation of functional anatomic meniscus constructs. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: December 19, 2020

2012 journal article

Tissue Engineering and Regenerative Medicine: Recent Innovations and the Transition to Translation

Tissue Engineering Part B: Reviews, 19(1), 1–13.

By: M. Fisher* & R. Mauck*

MeSH headings : Animals; Humans; Regenerative Medicine / trends; Tissue Engineering / trends; Tissue Scaffolds / trends; Translational Research, Biomedical / trends
topics (OpenAlex): Tissue Engineering and Regenerative Medicine; Pluripotent Stem Cells Research; Electrospun Nanofibers in Biomedical Applications
Sources: Crossref, NC State University Libraries
Added: October 23, 2025

2011 journal article

Alpha1,3-galactosyltransferase knockout does not alter the properties of porcine extracellular matrix bioscaffolds

Acta Biomaterialia, 7(4), 1719–1727.

By: R. Liang*, M. Fisher*, G. Yang*, C. Hall* & S. Woo*

author keywords: Extracellular matrix; Bioscaffold; Growth factors; alpha Gal
MeSH headings : Animals; Anterior Cruciate Ligament / metabolism; Anterior Cruciate Ligament / pathology; Biomechanical Phenomena; Blotting, Western; Bromodeoxyuridine / metabolism; Cell Proliferation; Extracellular Matrix / metabolism; Extracellular Matrix / pathology; Fibroblast Growth Factor 2 / metabolism; Galactosyltransferases / deficiency; Galactosyltransferases / metabolism; Gene Knockout Techniques; Humans; Immunohistochemistry; Intestinal Mucosa / pathology; Reproducibility of Results; Sus scrofa; Tissue Scaffolds / chemistry; Transforming Growth Factor beta1 / metabolism; Urinary Bladder / pathology
topics (OpenAlex): Tissue Engineering and Regenerative Medicine; Xenotransplantation and immune response; Electrospun Nanofibers in Biomedical Applications
TL;DR: The multidisciplinary results suggest that genetic modification to eliminate the αGal epitopes in the ECM bioscaffolds had not altered the properties of these ECMBioscaffolding and, as such, they should retain their performance in tissue engineering in humans. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 7, 2021

2011 journal article

Potential of healing a transected anterior cruciate ligament with genetically modified extracellular matrix bioscaffolds in a goat model

Knee Surgery, Sports Traumatology, Arthroscopy, 20(7), 1357–1365.

By: M. Fisher*, R. Liang*, H. Jung*, K. Kim*, G. Zamarra*, A. Almarza*, P. McMahon*, S. Woo*

MeSH headings : Animals; Anterior Cruciate Ligament / surgery; Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction / methods; Biomechanical Phenomena; Extracellular Matrix; Galactosyltransferases / deficiency; Goats; Guided Tissue Regeneration; Hydrogel, Polyethylene Glycol Dimethacrylate; Materials Testing; Models, Animal; Prostheses and Implants; Swine; Tissue Engineering; Tissue Scaffolds
topics (OpenAlex): Tissue Engineering and Regenerative Medicine; Knee injuries and reconstruction techniques; Tendon Structure and Treatment
TL;DR: The application of an ECM bioscaffold and hydrogel was found to accelerate the healing of a transected ACL following suture repair in the goat model with limited tissue hypertrophy and improvement in some of its biomechanical properties. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 7, 2021

2011 journal article

Suture augmentation following ACL injury to restore the function of the ACL, MCL, and medial meniscus in the goat stifle joint

Journal of Biomechanics, 44(8), 1530–1535.

By: M. Fisher*, H. Jung*, P. McMahon* & S. Woo*

author keywords: Anterior cruciate ligament (ACL); Suture augmentation; Biomechanics; Robotic/UFS testing system
MeSH headings : Animals; Anterior Cruciate Ligament / surgery; Anterior Cruciate Ligament Injuries; Biomechanical Phenomena; Goats; Humans; Knee Injuries / pathology; Knee Injuries / surgery; Medial Collateral Ligament, Knee / injuries; Medial Collateral Ligament, Knee / surgery; Menisci, Tibial / surgery; Models, Anatomic; Robotics; Suture Techniques; Sutures; Tibia / pathology; Tibial Meniscus Injuries
topics (OpenAlex): Knee injuries and reconstruction techniques; Tendon Structure and Treatment; Shoulder Injury and Treatment
TL;DR: Suture augmentation may be helpful in combination with FTE approaches for ACL healing by providing the needed initial joint stability while lowering the loads on the MM. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 7, 2021

2011 journal article

The effects of multiple freeze-thaw cycles on the biomechanical properties of the human bone-patellar tendon-bone allograft

Journal of Orthopaedic Research, 29(8), 1193–1198.

By: H. Jung*, G. Vangipuram*, M. Fisher*, G. Yang*, S. Hsu*, J. Bianchi, C. Ronholdt, S. Woo*

author keywords: anterior cruciate ligament reconstruction; bone-patellar tendon-bone allograft; multiple freeze-thaw cycles; biomechanics
MeSH headings : Adult; Aged; Biomechanical Phenomena; Bone-Patellar Tendon-Bone Grafting; Cryopreservation; Female; Freezing; Humans; Male; Middle Aged; Patellar Ligament
topics (OpenAlex): Knee injuries and reconstruction techniques; Total Knee Arthroplasty Outcomes; Orthopedic Surgery and Rehabilitation
TL;DR: It is suggested that the BPTB allografts used for anterior cruciate ligament reconstruction could potentially be re‐frozen without a loss in their biomechanical properties, given appropriate storage and care. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 7, 2021

2010 journal article

Evaluation of bone tunnel placement for suture augmentation of an injured anterior cruciate ligament: Effects on joint stability in a goat model

Journal of Orthopaedic Research, 28(10), 1373–1379.

By: M. Fisher*, H. Jung*, P. McMahon* & S. Woo*

author keywords: anterior cruciate ligament (ACL); suture augmentation; biomechanics; robotic testing system
MeSH headings : Animals; Anterior Cruciate Ligament / physiopathology; Anterior Cruciate Ligament / surgery; Anterior Cruciate Ligament Injuries; Biomechanical Phenomena; Goats; Joint Instability / physiopathology; Joint Instability / surgery; Knee Joint / physiopathology; Knee Joint / surgery; Male; Models, Animal; Range of Motion, Articular / physiology; Suture Techniques; Treatment Outcome
topics (OpenAlex): Knee injuries and reconstruction techniques; Total Knee Arthroplasty Outcomes; Sports injuries and prevention
TL;DR: Suture augmentation, when placed close to the ACL insertion, could be helpful in providing initial joint stability to aid ACL healing in the goat model. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 7, 2021

2009 journal article

Biomechanical evaluation of using one hamstrings tendon for ACL reconstruction: a human cadaveric study

Knee Surgery, Sports Traumatology, Arthroscopy, 18(1), 11–19.

By: G. Zamarra*, M. Fisher*, S. Woo* & G. Cerulli*

author keywords: ACL; ACL reconstruction; Semitendinosus tendon; Gracilis tendon; Knee kinematics; In situ forces in the ACL
MeSH headings : Adult; Anterior Cruciate Ligament / surgery; Anterior Cruciate Ligament Injuries; Biomechanical Phenomena; Cadaver; Humans; Knee Joint / physiology; Knee Joint / surgery; Middle Aged; Muscle, Skeletal / surgery; Orthopedic Procedures / methods; Range of Motion, Articular; Tendons / surgery; Tendons / transplantation; Transplantation, Autologous
topics (OpenAlex): Knee injuries and reconstruction techniques; Sports injuries and prevention; Tendon Structure and Treatment
TL;DR: The “All-inside” technique using either the semitendinosus or gracilis tendon for ACL reconstruction could satisfactorily restore time-zero knee kinematics and the in situ forces in either graft to those for the intact ACL, supporting clinical findings. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 7, 2021

2009 journal article

Evaluation of Knee Stability with Use of a Robotic System

Journal of Bone and Joint Surgery, 91(Supplement_1), 78–84.

By: S. Woo* & M. Fisher*

MeSH headings : Anterior Cruciate Ligament / physiopathology; Anterior Cruciate Ligament Injuries; Humans; Joint Instability / diagnosis; Knee Joint; Robotics
topics (OpenAlex): Knee injuries and reconstruction techniques; Total Knee Arthroplasty Outcomes; Tendon Structure and Treatment
Sources: Crossref, NC State University Libraries
Added: October 30, 2025

2009 journal article

Future of Orthopaedic Sports Medicine and Soft Tissue Healing: The Important Role of Engineering

Cellular and Molecular Bioengineering, 2(3), 448–461.

By: S. Woo*, R. Liang* & M. Fisher*

author keywords: Orthopaedics; Ligaments; Tendons; Functional tissue engineering; Biomechanics
topics (OpenAlex): Tendon Structure and Treatment; Knee injuries and reconstruction techniques; Bone fractures and treatments
TL;DR: The history of fundamental work done to characterize their biomechanical properties is detailed and some recent advances using functional tissue engineering strategies, including the use of bioscaffolds, to improve the healing of medial collateral ligament, patellar tendon, and anterior cruciate ligament are highlighted. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 7, 2021

2009 journal article

Role of biomechanics in the understanding of normal, injured, and healing ligaments and tendons

BMC Sports Science, Medicine and Rehabilitation, 1(1).

By: H. Jung*, M. Fisher* & S. Woo*

topics (OpenAlex): Knee injuries and reconstruction techniques; Tendon Structure and Treatment; Orthopedic Surgery and Rehabilitation
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: October 23, 2025

2008 journal article

Low-Serum Media and Dynamic Deformational Loading in Tissue Engineering of Articular Cartilage

Annals of Biomedical Engineering, 36(5), 769–779.

By: T. Kelly*, M. Fisher*, E. Oswald*, T. Tai*, R. Mauck*, G. Ateshian*, C. Hung*

MeSH headings : Animals; Cartilage, Articular / cytology; Cartilage, Articular / growth & development; Cattle; Cell Culture Techniques / methods; Cells, Cultured; Chondrocytes / cytology; Chondrocytes / physiology; Chondrogenesis / physiology; Culture Media, Serum-Free / metabolism; Elasticity; Mechanotransduction, Cellular / physiology; Serum / metabolism; Stress, Mechanical; Tissue Engineering / methods
topics (OpenAlex): Osteoarthritis Treatment and Mechanisms; Knee injuries and reconstruction techniques; Periodontal Regeneration and Treatments
TL;DR: The results show that low serum/ITS supplementation does not support the same level of tissue formation as compared to high serum controls, and low-serum/ITS media produced significant enhancement in tissue properties compared to constructs grown continuously in 20%FBS. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 7, 2021

2007 journal article

Use of a bioscaffold to improve healing of a patellar tendon defect after graft harvest for ACL reconstruction: A study in rabbits

Journal of Orthopaedic Research, 26(2), 255–263.

By: S. Karaoglu*, M. B. Fisher*, S. Woo*, Y. Fu*, R. Liang* & S. Abramowitch*

MeSH headings : Animals; Anterior Cruciate Ligament / anatomy & histology; Biomechanical Phenomena; Equipment Design; Female; Intestinal Mucosa / pathology; Models, Anatomic; Patellar Ligament / anatomy & histology; Rabbits; Plastic Surgery Procedures / methods; Swine; Tendons / anatomy & histology; Tendons / physiopathology; Tensile Strength; Wound Healing
topics (OpenAlex): Knee injuries and reconstruction techniques; Tissue Engineering and Regenerative Medicine; Tendon Structure and Treatment
Sources: Crossref, NC State University Libraries
Added: October 30, 2025

Employment

Updated: March 26th, 2024 12:04

2014 - present

North Carolina State University & University of North Carolina- Chapel Hill Raleigh, NC, US
Assistant Professor Biomedical Engineering

Education

Updated: September 12th, 2018 11:08

2011 - 2013

University of Pennsylvania Philadelphia, PA, US
Post-doctoral Fellow Orthopaedic Surgery

2005 - 2010

University of Pittsburgh Pittsburgh, PA, US
Ph.D. Bioengineering

2001 - 2005

Columbia University New York, NY, US
B.S. Biomedical Engineering

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