Works (5)

Updated: July 26th, 2025 05:02

2025 article

Azapeptide Atropisomers From Late-Stage N-Alkylations

Helton, M. E., Howard, C. S., Bruno, K. P., Cartrette, K. D., Bowles, M. O., Hearne, W. A., & Proulx, C. (2025, June 30). The Journal of Organic Chemistry, Vol. 90, pp. 9549–9558.

By: M. Helton n, C. Howard n, K. Bruno n, K. Cartrette n, M. Bowles n, W. Hearne*, C. Proulx n

topics (OpenAlex): Axial and Atropisomeric Chirality Synthesis; Molecular spectroscopy and chirality; Synthesis of heterocyclic compounds
Sources: Web Of Science, NC State University Libraries
Added: July 21, 2025

2025 article

Metallo-azapeptides: Controlled Metal Chelation to Peptide Backbone Nitrogen

Bowles, M. O., Willis, E. L., Trombley, M. D., Chen, C.-H., & Proulx, C. (2025, January 6). Journal of the American Chemical Society, Vol. 1.

By: M. Bowles n, E. Willis n, M. Trombley n, C. Chen* & C. Proulx n

MeSH headings : Chelating Agents / chemistry; Chelating Agents / chemical synthesis; Nitrogen / chemistry; Nickel / chemistry; Peptides / chemistry; Crystallography, X-Ray; Palladium / chemistry; Models, Molecular; Aza Compounds / chemistry; Coordination Complexes / chemistry
topics (OpenAlex): Chemical Synthesis and Analysis; Axial and Atropisomeric Chirality Synthesis; Asymmetric Synthesis and Catalysis
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Sources: Web Of Science, NC State University Libraries
Added: January 13, 2025

2022 article

Late-Stage N-Alkylation of Azapeptides

Bowles, M. O., & Proulx, C. (2022, February 28). Organic Letters, Vol. 3.

By: M. Bowles n & C. Proulx n

MeSH headings : Alkylation; Amino Acids; Aza Compounds / chemistry; Nitrogen; Tandem Mass Spectrometry
topics (OpenAlex): Chemical Synthesis and Analysis; RNA and protein synthesis mechanisms; Machine Learning in Bioinformatics
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Sources: Web Of Science, NC State University Libraries
Added: April 4, 2022

2021 article

Solid phase submonomer azapeptide synthesis

Bowles, M., & Proulx, C. (2021, January 1). Methods in Enzymology on CD-ROM/Methods in Enzymology.

By: M. Bowles n & C. Proulx n

MeSH headings : Amino Acids; Aza Compounds; Peptides; Peptidomimetics; Solid-Phase Synthesis Techniques
topics (OpenAlex): Chemical Synthesis and Analysis; Biochemical and Structural Characterization; Peptidase Inhibition and Analysis
TL;DR: This chapter provides a step-by-step protocol for the solid phase submonomer synthesis of azapeptides and focuses on semicarbazone functionalization by N-alkylation with primary alkyl halides, and describes conditions for coupling onto aza-amino acids. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: November 23, 2021

2021 article

Spectroscopic and Photophysical Investigation of Model Dipyrroles Common to Bilins: Exploring Natural Design for Steering Torsion to Divergent Functions

Staheli, C. F., Barney, J., Clark, T. R., Bowles, M., Jeppesen, B., Oblinsky, D. G., … Dean, J. C. (2021, February 17). Frontiers in Chemistry.

By: C. Staheli*, J. Barney*, T. Clark*, M. Bowles n, B. Jeppesen*, D. Oblinsky*, M. Steffensen*, J. Dean*

author keywords: torsional deactivation; Z-E isomerization; light harvesting; photoreception; Bilins; Dipyrroles; Phycobiliproteins
topics (OpenAlex): Photosynthetic Processes and Mechanisms; Photoreceptor and optogenetics research; Light effects on plants
TL;DR: The large oscillator strengths of the dipyrrolic derivatives and chemically-efficient spectral tunability seen through the ∼100 nm difference in absorption spectra, validate Nature's "selection" of multi-pyrrole pigments for light capture applications. (via Semantic Scholar)
Source: Web Of Science
Added: March 22, 2021

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