2022 article

Optimizing the First Response to Sepsis: An Electronic Health Record-Based Markov Decision Process Model

Rosenstrom, E., Meshkinfam, S., Ivy, J. S., Goodarzi, S. H., Capan, M., Huddleston, J., & Romero-Brufau, S. (2022, July 22). DECISION ANALYSIS, Vol. 7.

author keywords: clinical decision support; sepsis treatment; electronic health records; continuous-time Markov decision process; optimal stopping problem
TL;DR: A continuous-time Markov decision process (MDP) optimal stopping model is developed that identifies the optimal first intervention action (anti-infective, fluid, or wait) and an easily interpretable initial treatment heuristic that considers a patient’s organ dysfunction, location, and septic shock status is defined. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 8, 2022

2021 journal article

Proximity of Cellular and Physiological Response Failures in Sepsis

IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS, 25(11), 4089–4097.

By: A. Jazayeri*, M. Capan*, J. Ivy n, R. Arnold* & C. Yang*

author keywords: Physiology; Blood pressure; Biological systems; Statistics; Sociology; Predictive models; Hospitals; Sepsis prediction; proximate failures; sepsis feature selection
MeSH headings : Hospitalization; Humans; Machine Learning; Prognosis; Sepsis / diagnosis
TL;DR: This study identifies the dependency patterns of significant proximate sepsis-related failures of cellular and physiological responses using data from 12,223 adult patients hospitalized between July 2013 and December 2015 and reveals the few significant proxies that play the major roles in predicting patients’ outcomes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: November 23, 2021

2019 review

Objective measures of workload in healthcare: a narrative review

[Review of ]. INTERNATIONAL JOURNAL OF HEALTH CARE QUALITY ASSURANCE, 33(1), 1–17.

By: D. Fishbein*, S. Nambiar n, K. McKenzie n, M. Mayorga n, K. Miller*, K. Tran*, L. Schubel*, J. Agor*, T. Kim*, M. Capan*

Contributors: D. Fishbein*, S. Nambiar n, K. McKenzie n, M. Mayorga n, K. Miller*, K. Tran*, L. Schubel*, J. Agor*, T. Kim*, M. Capan*

author keywords: Workload; Care delivery needs of patients; Clinician performance; Objective workload; Task demand
MeSH headings : Electronic Health Records; Health Personnel / statistics & numerical data; Humans; Qualitative Research; Quality of Health Care; Tertiary Healthcare; Workload / classification; Workload / statistics & numerical data
TL;DR: An overview of objective measures of workload associated with direct care delivery in tertiary healthcare settings with a focus on measures that can be obtained from electronic records to inform operationalization of workload measurement is provided. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 21, 2020

2019 journal article

The value of missing information in severity of illness score development

JOURNAL OF BIOMEDICAL INFORMATICS, 97.

By: J. Agor*, O. Ozaltin*, J. Ivy*, M. Capan*, R. Arnold & S. Romero

Contributors: J. Agor*, O. Özaltın*, J. Ivy*, M. Capan*, R. Arnold & S. Romero

author keywords: Severity of illness scores; Sepsis; Missing data; Prediction models; Electronic health records
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Area Under Curve; Computational Biology / methods; Data Interpretation, Statistical; Electronic Health Records / statistics & numerical data; Female; Hospital Mortality; Humans; Intensive Care Units; Logistic Models; Male; Middle Aged; Models, Statistical; Outcome Assessment, Health Care / statistics & numerical data; Sepsis / mortality; Severity of Illness Index; Support Vector Machine; Young Adult
TL;DR: When developing prediction models using longitudinal EHR data, researchers should explore the incorporation of indicators for missing variables along with appropriate imputation to improve the performance of severity of illness scoring systems. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 27, 2020

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